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Phillip Brian Smith

Samuel L. Katz Distinguished Professor of Pediatrics
Pediatrics, Neonatology
DCRI, PO Box 17969, Durham, NC 27715
800 W. Morgan St Box 17969, DC 756, Durham, NC 27701

Selected Grants


North Carolina Clinical Center for the Eunice Kennedy Shiver NICHD Cooperative Multicenter Neonatal Research Network

ResearchCollaborating Investigator · Awarded by National Institutes of Health · 2001 - 2030

Duke KURe Program

Inst. Training Prgm or CMEMentor · Awarded by National Institute of Diabetes and Digestive and Kidney Diseases · 2013 - 2028

Stimulating Access to Research in Residency (StARR) - NHLBI

Inst. Training Prgm or CMEPreceptor · Awarded by National Heart, Lung, and Blood Institute · 2018 - 2028

HEAL Clinical Coordinating Resource Center for the Pain Management Effectiveness Research Network

ResearchCo Investigator · Awarded by National Institutes of Health · 2022 - 2027

POWER: Predicting Obesity with Enhanced EHR Resources

ResearchMentor · Awarded by Eunice Kennedy Shriver National Institute of Child Health and Human Development · 2022 - 2027

UNC-Duke Collaborative Clinical Pharmacology Postdoctoral Training Program

Inst. Training Prgm or CMEMentor · Awarded by University of North Carolina - Chapel Hill · 2016 - 2026

Duke-UNC Collaborative Pediatric Clinical Pharmacology Postdoctoral Training Program

Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 2021 - 2026

Duke Center for Advancement of Child Health (CAtCH).

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2021 - 2026

ECHO IDeA States Pediatric Clinical Trials Network - 2 (U24)

ResearchCo Investigator · Awarded by University of Arkansas for Medical Sciences · 2020 - 2025

Pharmacokinetics of Clonidine Administered in the Infant Population

ResearchCo-Mentor · Awarded by Thrasher Research Fund · 2022 - 2025

Environmental influences on Child Health Outcomes (ECHO) Coordinating Center

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2023 - 2025

Duke CTSA (TL1) Year 5

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2018 - 2024

Duke Summer Training in Academic Research (Duke's STAR)

ResearchMentor · Awarded by National Institutes of Health · 2018 - 2024

Unified Program for Therapeutics in Children

Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 2019 - 2024

Bridging the Gap to Enhance Clinical Research Program (BIGGER)

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2016 - 2023

ECHO Coordinating Center Administration Core

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2016 - 2023

ECHO Administrative Supplement - Neonatal Opioid Exposures

Clinical TrialPrincipal Investigator · Awarded by National Institutes of Health · 2016 - 2023

PTN TO #41: Sildenafil II

Clinical TrialPrincipal Investigator · Awarded by National Institutes of Health · 2015 - 2022

2/5 HEAL Consortium: Establishing Innovative Approaches for the HEALthy Brain and Child Development Study

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2019 - 2022

UNC-Duke Collaborative Clinical Pharmacology Postdoctoral Training Program

Inst. Training Prgm or CMEMentor · Awarded by University of North Carolina - Chapel Hill · 2020 - 2021

Pharmacokinetics, Pharmacodynamics, and Safety of Methylprednisolone in Neonates on Cardiopulmonary Bypass

ResearchAdvisor · Awarded by National Institutes of Health · 2017 - 2020

PTN TO#37 Obesity CNS PK Trial

Clinical TrialPrincipal Investigator · Awarded by National Institute for Child Health & Human Develo · 2015 - 2020

PTN TO# 35 Furosemide II

Clinical TrialPrincipal Investigator · Awarded by National Institute for Child Health & Human Develo · 2015 - 2020

PTN Task Order 25 SCAMP Modification

ResearchCo Investigator · Awarded by National Institutes of Health · 2014 - 2019

PTN TO #25 SCAMP

ResearchCo Investigator · Awarded by National Institutes of Health · 2013 - 2019

UNC-Duke Collaborative Clinical Pharmacology Postdoctoral Training Program

Inst. Training Prgm or CMEMentor · Awarded by University of North Carolina - Chapel Hill · 2017 - 2019

Echocardiogram to Diagnose Pulmonary Hypertension in Premature Infants

ResearchPrincipal Investigator · Awarded by University of North Carolina - Chapel Hill · 2015 - 2019

PTN Task Order: Safety of Furosemide in Premature Infants

Clinical TrialPrincipal Investigator · Awarded by National Institutes of Health · 2014 - 2019

PTN Task Order: CAFFEINE

Clinical TrialPrincipal Investigator · Awarded by National Institutes of Health · 2014 - 2019

Comparative Effectiveness of Vesicoureteral Reflux Treatments in Children

ResearchMentor · Awarded by National Institutes of Health · 2014 - 2019

SOLI - Solithromycin Pediatric Development Program (Phase 2/3)- Labor & Sub Cost

Clinical TrialCo Investigator · Awarded by Cempra Pharmaceuticals, Inc. · 2016 - 2018

Growth Failure in Extremely Preterm Infants: Microbiomic and Metabolomic Analysis

ResearchCollaborator · Awarded by Gerber Foundation · 2014 - 2018

PTN TO#44 Baby Mercy Tape II (TAP03)

Clinical TrialPrincipal Investigator · Awarded by National Institutes of Health · 2016 - 2018

Gastrin-Releasing Peptide and Bronchopulmonary Dysplasia

ResearchSignificant Contributor · Awarded by National Institutes of Health · 2011 - 2018

PTN TO #21- Pharmacokinetics of Multiple Dose Methadone in Children

Clinical TrialCo Investigator · Awarded by National Institutes of Health · 2013 - 2018

Linking Safety Practices to Adverse Events and Outcomes in Hospitalized Infants

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2015 - 2018

PTN TO 23-The Effect of Obesity on the Pharmacokinetics of Pantoprazole in Children

Clinical TrialCo-Principal Investigator · Awarded by National Institutes of Health · 2013 - 2018

PTN TO #34: Program Management Support

Clinical TrialCo Investigator · Awarded by National Institute for Child Health & Human Develo · 2016 - 2017

PTN TO#14 (Mod #3) - Efficacy of sildenafil in premature infants with Pulmonary Hypertension

ResearchCo Investigator · Awarded by National Institute for Child Health & Human Develo · 2015 - 2017

PTN Task Order #13: Pharmacokinetics of Antistaphylococcal Antibiotics in Infants

Clinical TrialCo Investigator · Awarded by National Institutes of Health · 2012 - 2017

The Duke Multidisciplinary Training Program in Pediatric Lung Disease

Inst. Training Prgm or CMEFaculty Member · Awarded by National Institutes of Health · 2010 - 2016

PTN Task Order 34 - Program Management Support

ResearchCo Investigator · Awarded by National Institutes of Health · 2015 - 2016

Efficacy of Antiviral Suppression Therapy after Neonatal HSV Infection of the CNS

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2015 - 2016

PTN Task Order--Protocol Development III

Clinical TrialCo Investigator · Awarded by National Institutes of Health · 2014 - 2015

PTN Task Order #16: Pediatrix Safety Study

ResearchCo Investigator · Awarded by National Institutes of Health · 2012 - 2015

PTN TO 22-Bronchopulmonary Dysplasia (BPD) and the Use of Diuretics in the NICU

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2013 - 2015

PTN Task Order #24: Protocol Development II

ResearchCo Investigator · Awarded by National Institutes of Health · 2013 - 2014

PTN Task Order #14: Sildenafil study

Clinical TrialCo Investigator · Awarded by National Institutes of Health · 2012 - 2014

PHARMACOKINETICS OF ANTIMICROBIAL AGENTS IN HIGH RISK INFANTS

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2009 - 2013

Accelerating Adoption of Comparative Effectiveness Research in Premature Infants

ResearchPrincipal Investigator · Awarded by Department of Health and Human Services · 2010 - 2013

North Carolina Collaborative PPRU Network

Clinical TrialCo Investigator · Awarded by National Institutes of Health · 2004 - 2010

Best Pharmaceutical for Children Act (BPCA): Use of Meropenem in Infants

Clinical TrialCo Investigator · Awarded by National Institutes of Health · 2007 - 2010

External Relationships


  • BioCryst Pharmaceuticals
  • Provepharm
  • Syneos Health
  • Tellus Therapeutics, Inc.

This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.