Overview
Antithrombotic Therapy in patients with Acute Coronary Syndromes
Elderly patients with Heart Disease
Biomarkers in Acute Coronary Syndromes and Atrial Fibrillation
Thrombosis and Anticoagulation and novel antithrombotic agents
Metabolomics in Cardiovascular Medicine
Current Appointments & Affiliations
Professor of Medicine
·
2021 - Present
Medicine, Cardiology,
Medicine
Member in the Duke Clinical Research Institute
·
2009 - Present
Duke Clinical Research Institute,
Institutes and Centers
Recent Publications
IVUS, OCT, or Angiography as Guidance for PCI in Complex Coronary Artery Lesions
Journal Article Jacc Cardiovascular Interventions · January 12, 2026 Background Intravascular imaging–guided percutaneous coronary intervention (PCI) reduces cardiovascular events compared with angiography-guided PCI alone. However, there is a paucity of data comparing these approaches in patients with complex coronary arte ... Full text CiteAlbiglutide and atrial fibrillation in patients with Type 2 diabetes and established cardiovascular disease: insights from the Harmony Outcomes trial.
Journal Article Eur J Prev Cardiol · January 6, 2026 AIMS: Atrial fibrillation and flutter (AF) are common in patients with Type 2 diabetes and are associated with worse outcomes. METHODS AND RESULTS: Harmony Outcomes was a multi-centre, event-driven, double-blind, placebo-controlled trial comparing the effe ... Full text Link to item CiteSacubitril/Valsartan vs Enalapril in Heart Failure Due to Chagas Disease: An Open-Label, Multicenter Randomized Clinical Trial.
Journal Article JAMA · January 6, 2026 IMPORTANCE: The efficacy and safety of guideline-recommended treatments for heart failure (HF) are uncertain in patients with Chagas disease. OBJECTIVE: To evaluate the efficacy and safety of the angiotensin receptor-neprilysin inhibitor sacubitril/valsart ... Full text Link to item CiteRecent Grants
Protocol CS12_CEC
Clinical TrialPrincipal Investigator · Awarded by Ionis Pharmaceuticals Inc · 2025 - 2029A PROGRAM OF THREE STUDIES IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS
Clinical TrialPrincipal Investigator · Awarded by Parexel International LLC · 2021 - 2029Priovant BREPO
Clinical TrialPrincipal Investigator · Awarded by Priovant Therapeutics, Inc · 2022 - 2027View All Grants
Education, Training & Certifications
Duke University, School of Medicine ·
2009
M.H.S.
Paulista Medical School, University of Sao Paulo (Brazil) ·
2006
Ph.D.
University of Santo Amaro (Brazil) ·
2001
M.D.