Renato Delascio Lopes | Scholars@Duke

Renato Delascio Lopes
Professor of Medicine

Atrial Fibrillation
Antithrombotic Therapy in patients with Acute Coronary Syndromes
Elderly patients with Heart Disease
Biomarkers in Acute Coronary Syndromes and Atrial Fibrillation
Thrombosis and Anticoagulation and novel antithrombotic agents
Metabolomics in Cardiovascular Medicine

Current Appointments & Affiliations

Professor of Medicine, Medicine, Cardiology, Medicine 2021
Member in the Duke Clinical Research Institute, Duke Clinical Research Institute, Institutes and Centers 2009

Contact Information

2400 Pratt St, Durham, NC 27710
Duke Box 3850, Durham, NC 27710
renato.lopes@duke.edu (919) 668-8596

Background
Education, Training, & Certifications
- M.H.S., Duke University School of Medicine 2009
- Ph.D., Paulista Medical School, University of Sao Paulo (Brazil) 2006
- M.D., University of Santo Amaro (Brazil) 2001
Duke Appointment History
- Professor of Medicine, Medicine, Cardiology, Medicine 2016 - 2020
- Associate Professor of Medicine, Medicine, Cardiology, Medicine 2013 - 2016
- Adjunct Assistant Professor in the Department of Medicine, Medicine, Clinical Pharmacology, Medicine 2009 - 2013
Recognition
In the News
- MAR 18, 2019 Duke Health News
  
  When Less is More: Some Heart Patients Should Skip Aspirin as Part of Treatment
- MAR 15, 2019 Duke Health News
  
  Your Treatment for Heart Disease May Not Be Backed by Good Science
- AUG 28, 2017 Duke Health News
  
  Education and Monitoring Improves the Use of Stroke-Prevention Therapies
Expertise
Global Scholarship
- Expertise
  - Brazil (Country)
- Research
  - Brazil (Country)
- Teaching
  - Brazil (Country)
Research
Selected Grants
- Balancing Risks and Benefits of Direct Oral Anticoagulants in Older Ischemic Stroke Patients with Atrial Fibrillation awarded by National Institutes of Health 2020 - 2025
- PRA-Ionis ATTR-CM awarded by Ionis Pharmaceuticals Inc 2020 - 2024
- MACE COMMITTEE COLLABORATION LOI awarded by GlaxoSmithKline 2020 - 2023
- Bayer-20115-CONVERT awarded by Bayer Healthcare Pharmaceuticals Inc 2020 - 2023
- CMS Linkage awarded by Bristoll Myers Squibb 2020 - 2023
- Bayer-21170-RE-THINc awarded by Bayer Healthcare Pharmaceuticals Inc 2020 - 2023
- H9X-MC-GBGO awarded by Eli Lilly and Company 2020 - 2022
- AF Detection, Diagnosis and Drug Therapy EDucational Program (AF-4Ds) awarded by THE AAD 2021
- Integrated Biostatistical Training for CVD Research awarded by North Carolina State University 2017 - 2021
- Trial to Assess Chelation Therapy 2 (TACT2) Data Coordinating Center awarded by National Institutes of Health 2015 - 2021
- Sanofi SOTA Outcomes EFC15156 awarded by Sanofi US 2018 - 2021
- Omecamtiv Mecarbil in Heart Failure awarded by Cytokinetics, Inc. 2018 - 2021
- Trial to Assess Chelation Therapy 2 (TACT2) Data Coordinating Center awarded by National Institutes of Health 2015 - 2020
- GSK-CKD program_CEC awarded by GlaxoSmithKline 2017 - 2020
- DCRI-Stanford CEC Summit awarded by Baim Institute for Clinical Research 2018 - 2020
- DCRI-Stanford CEC Summit awarded by WIRB-Copernicus Group 2018 - 2020
- DCRI-Stanford Symposium awarded by AG Mednet 2018 - 2020
- DCRI-Stanford Symposium awarded by Language Scientific, Inc. 2018 - 2020
- A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy, Safety, PK, and PD Effects of REGN2477-1033 in Obese Patients with Type 2 Diabetes Mellitus awarded by Regeneron Pharmaceuticals, Inc. 2018 - 2020
- Lilly GPGB Diabetes Study awarded by Eli Lilly and Company 2017 - 2019
- AMG785-2015242 awarded by Amgen, Inc. 2017 - 2018
- HeartRescue Brazil (RAPIDO) awarded by Research Triangle Institute International 2016 - 2018
- CEC Adjudications for Lilly GIP_GLP1 awarded by Eli Lilly and Company 2017 - 2018
- a retrospective re-review of all negatively adjudicated events (NAE) across three (3) protocols/studies awarded by Amgen, Inc. 2018
- Educational Preceptorship Agreement awarded by Pfizer, Inc. 2017 - 2018
- Bacteremia Modification 14 awarded by National Institutes of Health 2009 - 2017
- Mod 11 for Option 3 - Staphylococcal Bacteremia Study awarded by National Institutes of Health 2009 - 2017
- Modification No 13 Staphylococcal Bacteremia Study awarded by National Institutes of Health 2009 - 2017
- GBGJ Dulaglutide_CEC awarded by Eli Lilly and Company 2016 - 2017
- Modification No. 8 - Staphylococcal Bacteremia Study awarded by National Institutes of Health 2009 - 2016
Publications & Artistic Works
Selected Publications
- Books
  - Guimarães, H. P., A. D. Zazula, R. D. Lopes, and O. Berwanger. Practical Guidance for Patients with Acute Coronary Syndrome. San Paulo: Athenu, 2014.
  - Lopes, R. D., and R. A. Harrington, eds. Understanding Clinical Trials (Portuguese). New York: McGraw-Hill, 2014.
  - Lopes, R. D., and R. A. Harrington, eds. Understanding Clinical Trials. New York: McGraw-Hill, 2013.
  - Calff, R. M., and M. Roe. Acute Coronary Syndromes: ACE Essentials. Physicians Press, 2010.
  - Calff, R. M., and M. Roe. Acute Coronary Syndromes: ACE Essentials. Physicians Press, 2010.
  - Lopes, R. D. Acid-base and Hydro-electrolytic Balance. Editora Atheneu, 2009.
  - Lopes, A. C., R. D. Lopes, and F. Freire. Ambulatory Internal Medicine. Ed Sao Paulo: Editora Manolle, 2007.
  - Guimaraes, H. P., R. D. Lopes, and A. C. Lopes. Cardio-Respiratory Arrest. Ed Sao Paulo: Editora Atheneu, 2005.
- Academic Articles
  - Carnicelli, Anthony P., Sana M. Al-Khatib, Denis Xavier, Frederik Dalgaard, Peter D. Merrill, Daniel M. Wojdyla, Basil S. Lewis, et al. “Premature permanent discontinuation of apixaban or warfarin in patients with atrial fibrillation.” Heart 107, no. 9 (May 2021): 713–20. https://doi.org/10.1136/heartjnl-2020-317229.
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  - Lopes, Renato D., Pedro Gabriel Melo de Barros E Silva, Remo H. M. Furtado, Ariane Vieira Scarlatelli Macedo, Eduardo Ramacciotti, Lucas Petri Damini, Bruna Bronhara, et al. “Randomized Clinical Trial to Evaluate a Routine Full Anticoagulation Strategy in Patients with Coronavirus Infection (SARS-CoV2) Admitted to Hospital: Rationale and Design of the ACTION (AntiCoagulaTlon cOroNavirus)-Coalition IV Trial.” Am Heart J, April 20, 2021. https://doi.org/10.1016/j.ahj.2021.04.005.
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  - Gargiulo, Giuseppe, Christopher P. Cannon, Charles Michael Gibson, Andreas Goette, Renato D. Lopes, Jonas Oldgren, Serge Korjian, et al. “Safety and efficacy of double vs. triple antithrombotic therapy in patients with atrial fibrillation with or without acute coronary syndrome undergoing percutaneous coronary intervention: a collaborative meta-analysis of non-vitamin K antagonist oral anticoagulant-based randomized clinical trials.” Eur Heart J Cardiovasc Pharmacother 7, no. FI1 (April 9, 2021): f50–60. https://doi.org/10.1093/ehjcvp/pvaa116.
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  - Fudim, Marat, Manesh R. Patel, Richard Boortz-Marx, Barry A. Borlaug, Adam D. DeVore, Arun Ganesh, Cynthia L. Green, et al. “Splanchnic Nerve Block Mediated Changes in Stressed Blood Volume in Heart Failure.” Jacc Heart Fail 9, no. 4 (April 2021): 293–300. https://doi.org/10.1016/j.jchf.2020.12.006.
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  - Hijazi, Ziad, John H. Alexander, Zhuokai Li, Daniel M. Wojdyla, Roxana Mehran, Christopher B. Granger, Alexander Parkhomenko, et al. “Apixaban or Vitamin K Antagonists and Aspirin or Placebo According to Kidney Function in Patients With Atrial Fibrillation After Acute Coronary Syndrome or Percutaneous Coronary Intervention: Insights From the AUGUSTUS Trial.” Circulation 143, no. 12 (March 23, 2021): 1215–23. https://doi.org/10.1161/CIRCULATIONAHA.120.051020.
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  - Singh, Ajay K., Allison Blackorby, Borut Cizman, Kevin Carroll, Alexander R. Cobitz, Rich Davies, Vivekanand Jha, et al. “Study design and baseline characteristics of patients on dialysis in the ASCEND-D trial.” Nephrol Dial Transplant, March 21, 2021. https://doi.org/10.1093/ndt/gfab065.
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  - Prado, Gabriela M., Felix Mahfoud, Renato D. Lopes, Dalmo A. R. Moreira, Rodolfo Staico, Lucas P. Damiani, Christian Ukena, and Luciana V. Armaganijan. “Renal denervation for the treatment of ventricular arrhythmias: A systematic review and meta-analysis.” J Cardiovasc Electrophysiol, March 16, 2021. https://doi.org/10.1111/jce.15004.
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  - Berwanger, Otavio, Helio P. Guimarães, and Renato D. Lopes. “Rivaroxaban in Patients with Atrial Fibrillation and a Bioprosthetic Mitral Valve. Reply.” N Engl J Med 384, no. 10 (March 11, 2021): 975–76. https://doi.org/10.1056/NEJMc2035891.
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  - Harskamp, Ralf E., Wim A. M. Lucassen, Renato D. Lopes, Jelle C. L. Himmelreich, Gianfranco Parati, and Henk CPM van Weert. “Risk of stroke and bleeding in relation to hypertension in anticoagulated patients with atrial fibrillation: a meta-analysis of randomised controlled trials.” Acta Cardiol, March 8, 2021, 1–6. https://doi.org/10.1080/00015385.2021.1882111.
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  - Lopes, Renato D., Laine Thomas, Manuela Di Fusco, Allison Keshishian, Xuemei Luo, Xiaoyan Li, Cristina Masseria, et al. “Clinical and Economic Outcomes Among Nonvalvular Atrial Fibrillation Patients With Coronary Artery Disease and/or Peripheral Artery Disease.” Am J Cardiol, March 3, 2021. https://doi.org/10.1016/j.amjcard.2021.02.021.
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  - Al-Khatib, Sana M., Hillary Mulder, Daniel Wojdyla, Renato D. Lopes, Lars Wallentin, John H. Alexander, Ziad Hijazi, Shinya Goto, and Christopher B. Granger. “Apixaban Versus Warfarin in Patients With Atrial Fibrillation and Left Ventricular Hypertrophy: Insights From the ARISTOTLE Trial.” Circ Arrhythm Electrophysiol 14, no. 3 (March 2021): e009614. https://doi.org/10.1161/CIRCEP.120.009614.
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  - Al-Khatib, Sana M., Hillary Mulder, Daniel Wojdyla, Renato D. Lopes, Lars Wallentin, John H. Alexander, Ziad Hijazi, Shinya Goto, and Christopher B. Granger. “Apixaban Versus Warfarin in Patients With Atrial Fibrillation and Left Ventricular Hypertrophy.” Circulation: Arrhythmia and Electrophysiology 14, no. 3 (March 2021). https://doi.org/10.1161/circep.120.009614.
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  - Carnicelli, Anthony P., Hwanhee Hong, Robert P. Giugliano, Stuart J. Connolly, John Eikelboom, Manesh R. Patel, Lars Wallentin, et al. “Individual Patient Data from the Pivotal Randomized Controlled Trials of Non-Vitamin K Antagonist Oral Anticoagulants in Patients with Atrial Fibrillation (COMBINE AF): Design and Rationale: From the COMBINE AF (A Collaboration between Multiple institutions to Better Investigate Non-vitamin K antagonist oral anticoagulant use in Atrial Fibrillation) Investigators.” Am Heart J 233 (March 2021): 48–58. https://doi.org/10.1016/j.ahj.2020.12.002.
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  - Chery, Godefroy S., Nicholas Kamp, Andrzej S. Kosinski, Gillian Sanders Schmidler, Renato D. Lopes, Manesh Patel, and Sana M. Al-Khatib. “Response to: The paradox of implantable cardioverter-defibrillator: When guidelines play against care improvement.” Am Heart J 233 (March 2021): 151–52. https://doi.org/10.1016/j.ahj.2020.11.014.
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  - Pol, Tymon, Ziad Hijazi, Johan Lindbäck, John H. Alexander, M Cecilia Bahit, Raffaele De Caterina, J. W. Eikelboom, et al. “Evaluation of the prognostic value of GDF-15, ABC-AF-bleeding score and ABC-AF-death score in patients with atrial fibrillation across different geographical areas.” Open Heart 8, no. 1 (March 2021). https://doi.org/10.1136/openhrt-2020-001471.
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  - Ronsoni, Rafael M., Tiago L. Silvestrini, Vidal Essebag, Renato D. Lopes, Marco Aurélio Lumertz Saffi, and Tiago Luiz Luz Leiria. “Association of the left common ostium with clinical outcome after pulmonary vein isolation in atrial fibrillation.” Indian Pacing Electrophysiol J 21, no. 2 (March 2021): 95–100. https://doi.org/10.1016/j.ipej.2020.11.020.
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  - Salah, Husam M., Subhi J. Al’Aref, Muhammad Shahzeb Khan, Malek Al-Hawwas, Srikanth Vallurupalli, Jawahar L. Mehta, J Paul Mounsey, et al. “Effects of sodium-glucose cotransporter 1 and 2 inhibitors on cardiovascular and kidney outcomes in type 2 diabetes: A meta-analysis update.” Am Heart J 233 (March 2021): 86–91. https://doi.org/10.1016/j.ahj.2020.12.007.
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  - Chaitman, Bernard R., Karen P. Alexander, Derek D. Cyr, Jeffrey S. Berger, Harmony R. Reynolds, Sripal Bangalore, William E. Boden, et al. “Myocardial Infarction in the ISCHEMIA Trial: Impact of Different Definitions on Incidence, Prognosis, and Treatment Comparisons.” Circulation 143, no. 8 (February 23, 2021): 790–804. https://doi.org/10.1161/CIRCULATIONAHA.120.047987.
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  - Angiolillo, Dominick J., Deepak L. Bhatt, Christopher P. Cannon, John W. Eikelboom, C Michael Gibson, Shaun G. Goodman, Christopher B. Granger, et al. “Antithrombotic Therapy in Patients With Atrial Fibrillation Treated With Oral Anticoagulation Undergoing Percutaneous Coronary Intervention: A North American Perspective: 2021 Update.” Circulation 143, no. 6 (February 9, 2021): 583–96. https://doi.org/10.1161/CIRCULATIONAHA.120.050438.
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  - Aflaki, Mona, Alexandria Flannery, João Pedro Ferreira, Matthew Pellan Cheng, Nadine Kronfli, Ariane Marelli, Faiez Zannad, et al. “Management of Renin-Angiotensin-Aldosterone System blockade in patients admitted to hospital with confirmed coronavirus disease (COVID-19) infection (The McGill RAAS-COVID- 19): A structured summary of a study protocol for a randomized controlled trial.” Trials 22, no. 1 (February 5, 2021): 115. https://doi.org/10.1186/s13063-021-05080-4.
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  - Fernandes, Fábio, Carlos Henrique Valente Moreira, Lea Campos Oliveira, Marcela Souza-Basqueira, Barbara Maria Ianni, Claudia di Lorenzo, Felix José Alvarez Ramires, et al. “Galectin-3 Associated with Severe Forms and Long-term Mortality in Patients with Chagas Disease.” Arq Bras Cardiol 116, no. 2 (February 2021): 248–56. https://doi.org/10.36660/abc.20190403.
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  - Lopes, Renato D., Amit N. Vora, and John H. Alexander. “Antithrombotic Strategies in Patients With Atrial Fibrillation and Percutaneous Coronary Intervention-Reply.” Jama Cardiol 6, no. 2 (February 1, 2021): 241. https://doi.org/10.1001/jamacardio.2020.4759.
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  - Salah, Husam M., Subhi J. Al’Aref, Muhammad Shahzeb Khan, Malek Al-Hawwas, Srikanth Vallurupalli, Jawahar L. Mehta, J Paul Mounsey, et al. “Effect of sodium-glucose cotransporter 2 inhibitors on cardiovascular and kidney outcomes-Systematic review and meta-analysis of randomized placebo-controlled trials.” Am Heart J 232 (February 2021): 10–22. https://doi.org/10.1016/j.ahj.2020.10.064.
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  - Varshney, Anubodh S., David E. Wang, Ankeet S. Bhatt, Alexander Blood, Musa A. Sharkawi, Hasan K. Siddiqi, Muthiah Vaduganathan, et al. “Characteristics of clinical trials evaluating cardiovascular therapies for Coronavirus Disease 2019 Registered on ClinicalTrials.gov: a cross sectional analysis.” Am Heart J 232 (February 2021): 105–15. https://doi.org/10.1016/j.ahj.2020.10.065.
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  - Benjamin, Emelia J., Alan S. Go, Patrice Desvigne-Nickens, Christopher D. Anderson, Barbara Casadei, Lin Y. Chen, Harry J. G. M. Crijns, et al. “Research Priorities in Atrial Fibrillation Screening: A Report From a National Heart, Lung, and Blood Institute Virtual Workshop.” Circulation 143, no. 4 (January 26, 2021): 372–88. https://doi.org/10.1161/CIRCULATIONAHA.120.047633.
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  - Veiga, Viviane C., João A. G. G. Prats, Danielle L. C. Farias, Regis G. Rosa, Leticia K. Dourado, Fernando G. Zampieri, Flávia R. Machado, et al. “Effect of tocilizumab on clinical outcomes at 15 days in patients with severe or critical coronavirus disease 2019: randomised controlled trial.” Bmj 372 (January 20, 2021): n84. https://doi.org/10.1136/bmj.n84.
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  - Lopes, Renato D., Ariane V. S. Macedo, Pedro G. M. de Barros E Silva, Renata J. Moll-Bernardes, Tiago M. Dos Santos, Lilian Mazza, André Feldman, et al. “Effect of Discontinuing vs Continuing Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers on Days Alive and Out of the Hospital in Patients Admitted With COVID-19: A Randomized Clinical Trial.” Jama 325, no. 3 (January 19, 2021): 254–64. https://doi.org/10.1001/jama.2020.25864.
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  - Nelson, Adam J., Maddalena Ardissino, Kevin Haynes, Sonali Shambhu, Zubin J. Eapen, Darren K. McGuire, Anthony Carnicelli, et al. “Gaps in Evidence-Based Therapy Use in Insured Patients in the United States With Type 2 Diabetes Mellitus and Atherosclerotic Cardiovascular Disease.” J Am Heart Assoc 10, no. 2 (January 19, 2021): e016835. https://doi.org/10.1161/JAHA.120.016835.
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  - Sarpe, A. K. P., C. D. Q. Flumignan, L. C. U. Nakano, V. F. M. Trevisani, R. D. Lopes, H. J. Guedes Neto, and R. L. G. Flumignan. “Duplex ultrasound for surveillance of lower limb revascularisation.” Cochrane Database of Systematic Reviews 2021, no. 1 (January 19, 2021). https://doi.org/10.1002/14651858.CD013852.
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  - Bhatt, Deepak L., Michael Szarek, Bertram Pitt, Christopher P. Cannon, Lawrence A. Leiter, Darren K. McGuire, Julia B. Lewis, et al. “Sotagliflozin in Patients with Diabetes and Chronic Kidney Disease.” N Engl J Med 384, no. 2 (January 14, 2021): 129–39. https://doi.org/10.1056/NEJMoa2030186.
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  - Bhatt, Deepak L., Michael Szarek, P Gabriel Steg, Christopher P. Cannon, Lawrence A. Leiter, Darren K. McGuire, Julia B. Lewis, et al. “Sotagliflozin in Patients with Diabetes and Recent Worsening Heart Failure.” N Engl J Med 384, no. 2 (January 14, 2021): 117–28. https://doi.org/10.1056/NEJMoa2030183.
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  - Fanaroff, Alexander C., and Renato D. Lopes. “Anticoagulation dosing in atherosclerotic cardiovascular disease: Is less more?” Eur J Intern Med 83 (January 2021): 8–9. https://doi.org/10.1016/j.ejim.2020.12.004.
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  - Fanaroff, Alexander C., and Renato D. Lopes. “Antithrombotic Regimens in Low-Risk Patients Undergoing Transcatheter Aortic Valve Replacement: Trials Evaluating Patient-Centered Outcomes Needed.” Circ Cardiovasc Interv 14, no. 1 (January 2021): e010331. https://doi.org/10.1161/CIRCINTERVENTIONS.120.010331.
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  - Guimarães, Helio P., Pedro G. M. de Barros E Silva, Idelzuita L. Liporace, Roney O. Sampaio, Flávio Tarasoutchi, Milena Paixão, Conrado R. Hoffmann-Filho, et al. “A randomized clinical trial to evaluate the efficacy and safety of rivaroxaban in patients with bioprosthetic mitral valve and atrial fibrillation or flutter: Rationale and design of the RIVER trial.” Am Heart J 231 (January 2021): 128–36. https://doi.org/10.1016/j.ahj.2020.10.001.
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  - Jawitz, Oliver K., Amanda S. Stebbins, Vignesh Raman, Brooke Alhanti, Sean van Diepen, Matthias Heringlake, Stephen Fremes, et al. “Association between levosimendan, postoperative AKI, and mortality in cardiac surgery: Insights from the LEVO-CTS trial.” Am Heart J 231 (January 2021): 18–24. https://doi.org/10.1016/j.ahj.2020.10.066.
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  - Jerjes-Sánchez, Carlos, David Rodriguez, Alfredo E. Farjat, Gloria Kayani, Peter MacCallum, Renato D. Lopes, Alexander G. G. Turpie, et al. “Pregnancy-Associated Venous Thromboembolism: Insights from GARFIELD-VTE.” Th Open 5, no. 1 (January 2021): e24–34. https://doi.org/10.1055/s-0040-1722611.
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  - Rosa, Regis Goulart, Caroline Cabral Robinson, Viviane Cordeiro Veiga, Alexandre Biasi Cavalcanti, Luciano César Pontes de Azevedo, Flávia Ribeiro Machado, Otavio Berwanger, et al. “Quality of life and long-term outcomes after hospitalization for COVID-19: Protocol for a prospective cohort study (Coalition VII).” Rev Bras Ter Intensiva 33, no. 1 (January 2021): 31–37. https://doi.org/10.5935/0103-507X.20210003.
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  - Silva, Pedro Gabriel Melo de Barros E., Otavio Berwanger, Dalton Bertolim Precoma, Margaret Assad Cavalcante, José Fernando Vilela-Martin, Estêvão Lanna Figueiredo, Renato Delascio Lopes, et al. “Evaluation of 1-Year Follow-up of Patients Included in the Registry of Clinical Practice in Patients at High Cardiovascular Risk (REACT).” Arq Bras Cardiol 116, no. 1 (January 2021): 108–16. https://doi.org/10.36660/abc.20190885.
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  - De Caterina, Raffaele, Giuseppe Patti, Johan Westerbergh, John Horowitz, Justin A. Ezekowitz, Basil S. Lewis, Renato D. Lopes, et al. “Heterogeneity of diabetes as a risk factor for major adverse cardiovascular events in anticoagulated patients with atrial fibrillation: an analysis of the ARISTOTLE trial.” Eur Heart J Cardiovasc Pharmacother, December 28, 2020. https://doi.org/10.1093/ehjcvp/pvaa140.
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  - Gargiulo, Giuseppe, Christopher P. Cannon, C Michael Gibson, Renato D. Lopes, Pascal Vranckx, and Marco Valgimigli. “The multiplication of loaves and fishes approach: A Critic to Double anti-thrombotics or to Double number of ischemic events?” Eur Heart J Cardiovasc Pharmacother, December 19, 2020. https://doi.org/10.1093/ehjcvp/pvaa141.
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  - Hijazi, Ziad, Lars Wallentin, Johan Lindbäck, John H. Alexander, Stuart J. Connolly, John W. Eikelboom, Michael D. Ezekowitz, et al. “Screening of Multiple Biomarkers Associated With Ischemic Stroke in Atrial Fibrillation.” J Am Heart Assoc 9, no. 24 (December 15, 2020): e018984. https://doi.org/10.1161/JAHA.120.018984.
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  - Fanaroff, Alexander C., and Renato D. Lopes. “Antithrombotic therapy for patients with atrial fibrillation undergoing percutaneous coronary intervention: balance best with double antithrombotic therapy.” Eur Heart J 41, no. 47 (December 14, 2020): 4505–7. https://doi.org/10.1093/eurheartj/ehaa683.
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  - Zimerman, André, Renato D. Lopes, André D’Ávila, Luis E. Rohde, and Leandro I. Zimerman. “COVID-19 in Brazil: the headlines should be about science.” Lancet 396, no. 10265 (December 5, 2020): 1803. https://doi.org/10.1016/S0140-6736(20)32375-8.
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  - Boriani, Giuseppe, Renate B. Schnabel, Jeff S. Healey, Renato D. Lopes, Nicole Verbiest-van Gurp, Trudie Lobban, John A. Camm, and Ben Freedman. “Consumer-led screening for atrial fibrillation using consumer-facing wearables, devices and apps: A survey of health care professionals by AF-SCREEN international collaboration.” Eur J Intern Med 82 (December 2020): 97–104. https://doi.org/10.1016/j.ejim.2020.09.005.
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  - Dalgaard, Frederik, Haolin Xu, Roland A. Matsouaka, Andrea M. Russo, Anne B. Curtis, Peter Vibe Rasmussen, Martin H. Ruwald, et al. “Management of Atrial Fibrillation in Older Patients by Morbidity Burden: Insights From Get With The Guidelines-Atrial Fibrillation.” J Am Heart Assoc 9, no. 23 (December 2020): e017024. https://doi.org/10.1161/JAHA.120.017024.
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  - Guimarães, Helio P., Renato D. Lopes, Pedro G. M. de Barros E Silva, Idelzuita L. Liporace, Roney O. Sampaio, Flávio Tarasoutchi, Conrado R. Hoffmann-Filho, et al. “Rivaroxaban in Patients with Atrial Fibrillation and a Bioprosthetic Mitral Valve.” N Engl J Med 383, no. 22 (November 26, 2020): 2117–26. https://doi.org/10.1056/NEJMoa2029603.
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  - Cavalcanti, Alexandre B., Fernando G. Zampieri, Regis G. Rosa, Luciano C. P. Azevedo, Viviane C. Veiga, Alvaro Avezum, Lucas P. Damiani, et al. “Hydroxychloroquine with or without Azithromycin in Mild-to-Moderate Covid-19.” N Engl J Med 383, no. 21 (November 19, 2020): 2041–52. https://doi.org/10.1056/NEJMoa2019014.
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  - Lopes, Renato D., Samantha E. Berger, Manuela Di Fusco, Amiee Kang, Cristina Russ, Abena Afriyie, Amy Earley, Sohan Deshpande, and Lorenzo G. Mantovani. “A review of global health technology assessments of non-VKA oral anticoagulants in non-valvular atrial fibrillation.” Int J Cardiol 319 (November 15, 2020): 85–93. https://doi.org/10.1016/j.ijcard.2020.06.061.
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  - Kamp, Nicholas J., Godefroy Chery, Andrzej S. Kosinski, Milind Y. Desai, Oussama Wazni, Gillian Sanders Schmidler, Manesh Patel, Renato D. Lopes, Daniel P. Morin, and Sana M. Al-Khatib. “Risk stratification using late gadolinium enhancement on cardiac magnetic resonance imaging in patients with hypertrophic cardiomyopathy: A systematic review and meta-analysis.” Prog Cardiovasc Dis, November 7, 2020. https://doi.org/10.1016/j.pcad.2020.11.001.
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  - Lopes, Renato D., Karen P. Alexander, Susanna R. Stevens, Harmony R. Reynolds, Gregg W. Stone, Ileana L. Piña, Frank W. Rockhold, et al. “Initial Invasive Versus Conservative Management of Stable Ischemic Heart Disease in Patients With a History of Heart Failure or Left Ventricular Dysfunction: Insights From the ISCHEMIA Trial.” Circulation 142, no. 18 (November 3, 2020): 1725–35. https://doi.org/10.1161/CIRCULATIONAHA.120.050304.
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  - Chery, Godefroy, Nicholas Kamp, Andrzej S. Kosinski, Gillian Sanders Schmidler, Renato D. Lopes, Manesh Patel, and Sana M. Al-Khatib. “Prognostic value of myocardial fibrosis on cardiac magnetic resonance imaging in patients with ischemic cardiomyopathy: A systematic review.” Am Heart J 229 (November 2020): 52–60. https://doi.org/10.1016/j.ahj.2020.08.004.
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  - Kochar, Ajar, Hillary Mulder, Frank W. Rockhold, Iris Baumgartner, Jeffrey S. Berger, Juuso I. Blomster, F Gerry R. Fowkes, et al. “Cause of Death Among Patients With Peripheral Artery Disease: Insights From the EUCLID Trial.” Circ Cardiovasc Qual Outcomes 13, no. 11 (November 2020): e006550. https://doi.org/10.1161/CIRCOUTCOMES.120.006550.
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  - Wallentin, Lars, Johan Lindbäck, Niclas Eriksson, Ziad Hijazi, John W. Eikelboom, Michael D. Ezekowitz, Christopher B. Granger, et al. “Angiotensin-converting enzyme 2 (ACE2) levels in relation to risk factors for COVID-19 in two large cohorts of patients with atrial fibrillation.” Eur Heart J 41, no. 41 (November 1, 2020): 4037–46. https://doi.org/10.1093/eurheartj/ehaa697.
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  - Lopes, Renato D., and Alexander C. Fanaroff. “Anticoagulation in COVID-19: It Is Time for High-Quality Evidence.” J Am Coll Cardiol 76, no. 16 (October 20, 2020): 1827–29. https://doi.org/10.1016/j.jacc.2020.09.008.
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  - Tomazini, Bruno M., Israel S. Maia, Alexandre B. Cavalcanti, Otavio Berwanger, Regis G. Rosa, Viviane C. Veiga, Alvaro Avezum, et al. “Effect of Dexamethasone on Days Alive and Ventilator-Free in Patients With Moderate or Severe Acute Respiratory Distress Syndrome and COVID-19: The CoDEX Randomized Clinical Trial.” Jama 324, no. 13 (October 6, 2020): 1307–16. https://doi.org/10.1001/jama.2020.17021.
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  - Furtado, Remo H. M., Otavio Berwanger, Henrique A. Fonseca, Thiago D. Corrêa, Leonardo R. Ferraz, Maura G. Lapa, Fernando G. Zampieri, et al. “Azithromycin in addition to standard of care versus standard of care alone in the treatment of patients admitted to the hospital with severe COVID-19 in Brazil (COALITION II): a randomised clinical trial.” Lancet 396, no. 10256 (October 3, 2020): 959–67. https://doi.org/10.1016/S0140-6736(20)31862-6.
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  - Jawitz, Oliver K., Morgan L. Cox, David Ranney, Judson B. Williams, Hillary Mulder, Mario F. L. Gaudino, Stephen Fremes, et al. “Outcomes following revascularization with radial artery bypass grafts: Insights from the PREVENT-IV trial.” Am Heart J 228 (October 2020): 91–97. https://doi.org/10.1016/j.ahj.2020.08.001.
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  - Lopes, Renato D., Jan Steffel, Manuela Di Fusco, Allison Keshishian, Xuemei Luo, Xiaoyan Li, Cristina Masseria, et al. “Corrigendum to "Effectiveness and Safety of Oral Anticoagulants in Adults with Non-valvular Atrial Fibrillation Patients and Concomitant Coronary/Peripheral Artery Disease" American Journal of Medicine 131:09 (2018): 1074-1085.e4.” Am J Med 133, no. 10 (October 2020): 1229–38. https://doi.org/10.1016/j.amjmed.2020.06.003.
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  - Ranney, David N., Judson B. Williams, Álvaro S. Albrecht, Shuang Li, Renato A. K. Kalil, Eric D. Peterson, and Renato D. Lopes. “Insulin Use and Clinical Outcomes in Patients Undergoing Coronary Artery Bypass Graft Surgery.” Braz J Cardiovasc Surg 35, no. 5 (October 1, 2020): 666–74. https://doi.org/10.21470/1678-9741-2019-0347.
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  - Hijazi, Ziad, Christopher B. Granger, Stefan H. Hohnloser, Johan Westerbergh, Johan Lindbäck, John H. Alexander, Matyas Keltai, et al. “Association of Different Estimates of Renal Function With Cardiovascular Mortality and Bleeding in Atrial Fibrillation.” J Am Heart Assoc 9, no. 18 (September 15, 2020): e017155. https://doi.org/10.1161/JAHA.120.017155.
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  - Aulin, Julia, Ziad Hijazi, Agneta Siegbahn, Ulrika Andersson, John H. Alexander, Stuart J. Connolly, Michael D. Ezekowitz, et al. “Serial measurement of interleukin-6 and risk of mortality in anticoagulated patients with atrial fibrillation: Insights from ARISTOTLE and RE-LY trials.” J Thromb Haemost 18, no. 9 (September 2020): 2287–95. https://doi.org/10.1111/jth.14947.
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  - Biagioni, Rodrigo Bruno, Renato Delascio Lopes, Leandro Barile Agati, Roberto Sacilotto, Nelson Wolosker, Marcone Lima Sobreira, Bruno Leonardo de Freitas Soares, et al. “Rationale and design for the study Apixaban versus ClopidoGRel on a background of aspirin in patient undergoing InfraPoPliteal angioplasty for critical limb ischemia: AGRIPPA trial.” Am Heart J 227 (September 2020): 100–106. https://doi.org/10.1016/j.ahj.2020.06.010.
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  - Hijazi, Ziad, Jonas Oldgren, Johan Lindbäck, John H. Alexander, Marco Alings, Raffaele De Caterina, John W. Eikelboom, et al. “Evaluation of the Age, Biomarkers, and Clinical History-Bleeding Risk Score in Patients With Atrial Fibrillation With Combined Aspirin and Anticoagulation Therapy Enrolled in the ARISTOTLE and RE-LY Trials.” Jama Netw Open 3, no. 9 (September 1, 2020): e2015943. https://doi.org/10.1001/jamanetworkopen.2020.15943.
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  - Jawitz, Oliver K., Tracy Y. Wang, Renato D. Lopes, Alma Chavez, Brittanny Boyer, Hwasoon Kim, Kevin J. Anstrom, et al. “Rationale and design of PROACT Xa: A randomized, multicenter, open-label, clinical trial to evaluate the efficacy and safety of apixaban versus warfarin in patients with a mechanical On-X Aortic Heart Valve.” Am Heart J 227 (September 2020): 91–99. https://doi.org/10.1016/j.ahj.2020.06.014.
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  - Sobhy, Mohamed A., Maurice Khoury, Wael A. Almahmeed, Janvi Sah, Manuela Di Fusco, Jack Mardekian, Sid Ahmed Kherraf, Renato D. Lopes, and Ahmad Hersi. “The atrial FibriLlatiOn real World management registry in the Middle East and Africa: design and rationale.” J Cardiovasc Med (Hagerstown) 21, no. 9 (September 2020): 704–10. https://doi.org/10.2459/JCM.0000000000001007.
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  - Rasmussen, Peter Vibe, Jannik Langtved Pallisgaard, Morten Lock Hansen, Gunnar Hilmar Gislason, Christian Torp-Pedersen, Martin Ruwald, Karen P. Alexander, Renato D. Lopes, Sana M. Al-Khatib, and Frederik Dalgaard. “Treatment of Older Patients with Atrial Fibrillation by Morbidity Burden.” Eur Heart J Qual Care Clin Outcomes, August 28, 2020. https://doi.org/10.1093/ehjqcco/qcaa070.
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  - Capodanno, Davide, Marco Di Maio, Antonio Greco, Deepak L. Bhatt, C Michael Gibson, Andreas Goette, Renato D. Lopes, Roxana Mehran, Pascal Vranckx, and Dominick J. Angiolillo. “Safety and Efficacy of Double Antithrombotic Therapy With Non-Vitamin K Antagonist Oral Anticoagulants in Patients With Atrial Fibrillation Undergoing Percutaneous Coronary Intervention: A Systematic Review and Meta-Analysis.” J Am Heart Assoc 9, no. 16 (August 18, 2020): e017212. https://doi.org/10.1161/JAHA.120.017212.
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  - Fanaroff, Alexander C., Robert M. Califf, Robert A. Harrington, Christopher B. Granger, John J. V. McMurray, Manesh R. Patel, Deepak L. Bhatt, et al. “Randomized Trials Versus Common Sense and Clinical Observation: JACC Review Topic of the Week.” J Am Coll Cardiol 76, no. 5 (August 4, 2020): 580–89. https://doi.org/10.1016/j.jacc.2020.05.069.
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  - Berglund, Erik, Lars Wallentin, Jonas Oldgren, Henrik Renlund, John H. Alexander, Christopher B. Granger, Stefan H. Hohnloser, et al. “Effects of apixaban compared with warfarin as gain in event-free time - a novel assessment of the results of the ARISTOTLE trial.” Eur J Prev Cardiol 27, no. 12 (August 2020): 1311–19. https://doi.org/10.1177/2047487319886959.
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  - Diepen, Sean van, Judith S. Hochman, Amanda Stebbins, Carlos L. Alviar, John H. Alexander, and Renato D. Lopes. “Association Between Delays in Mechanical Ventilation Initiation and Mortality in Patients With Refractory Cardiogenic Shock.” Jama Cardiol 5, no. 8 (August 1, 2020): 965–67. https://doi.org/10.1001/jamacardio.2020.1274.
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  - Fanaroff, Alexander C., Marat Fudim, Robert M. Califf, Stephan Windecker, Sidney C. Smith, and Renato D. Lopes. “Levels of evidence supporting drug, device, and other recommendations in the American Heart Association/American College of Cardiology guidelines.” Am Heart J 226 (August 2020): 4–12. https://doi.org/10.1016/j.ahj.2020.05.003.
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  - Fudim, Marat, Vanessa L. Blumer, Renato D. Lopes, Patrick Rossignol, Michael Feldschuh, Wayne L. Miller, and Paul A. Sobotka. “Correlation of Quantitated Intravascular Volume with Blood Pressure in Patients with Systemic Hypertension.” J Cardiovasc Transl Res 13, no. 4 (August 2020): 528–30. https://doi.org/10.1007/s12265-019-09910-4.
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  - Lopes, Renato D., Ariane Vieira Scarlatelli Macedo, Pedro Gabriel Melo de Barros E Silva, Renata Junqueira Moll-Bernardes, Andre Feldman, Guilherme D’Andréa Saba Arruda, Andrea Silvestre de Souza, et al. “Continuing versus suspending angiotensin-converting enzyme inhibitors and angiotensin receptor blockers: Impact on adverse outcomes in hospitalized patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)--The BRACE CORONA Trial.” Am Heart J 226 (August 2020): 49–59. https://doi.org/10.1016/j.ahj.2020.05.002.
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  - Røsjø, H., Z. Hijazi, T. Omland, J. Westerbergh, M. N. Lyngbakken, J. H. Alexander, B. J. Gersh, et al. “Cardiac troponin is associated with cardiac outcomes in men and women with atrial fibrillation, insights from the ARISTOTLE trial.” J Intern Med 288, no. 2 (August 2020): 248–59. https://doi.org/10.1111/joim.13072.
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  - Sullivan, Alexander E., Michael G. Nanna, Sunil V. Rao, Sarah Cantrell, C Michael Gibson, Freek W. A. Verheugt, Eric D. Peterson, et al. “A systematic review of randomized trials comparing double versus triple antithrombotic therapy in patients with atrial fibrillation undergoing percutaneous coronary intervention.” Catheter Cardiovasc Interv 96, no. 2 (August 2020): E102–9. https://doi.org/10.1002/ccd.28535.
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  - Marquis-Gravel, Guillaume, Frederik Dalgaard, Aaron D. Jones, Yuliya Lokhnygina, Stefan K. James, Robert A. Harrington, Lars Wallentin, et al. “Post-Discharge Bleeding and Mortality Following Acute Coronary Syndromes With or Without PCI.” J Am Coll Cardiol 76, no. 2 (July 14, 2020): 162–71. https://doi.org/10.1016/j.jacc.2020.05.031.
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  - Farias, Danielle Leão Cordeiro de, João Prats, Alexandre Biasi Cavalcanti, Regis Goulart Rosa, Flávia Ribeiro Machado, Otávio Berwanger, Luciano César Pontes de Azevedo, et al. “Rationale and design of the "Tocilizumab in patients with moderate to severe COVID-19: an open-label multicentre randomized controlled" trial (TOCIBRAS).” Rev Bras Ter Intensiva 32, no. 3 (July 2020): 337–47. https://doi.org/10.5935/0103-507X.20200060.
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  - Reynolds, Harmony R., Leslee J. Shaw, James K. Min, John A. Spertus, Bernard R. Chaitman, Daniel S. Berman, Michael H. Picard, et al. “Association of Sex With Severity of Coronary Artery Disease, Ischemia, and Symptom Burden in Patients With Moderate or Severe Ischemia: Secondary Analysis of the ISCHEMIA Randomized Clinical Trial.” Jama Cardiol 5, no. 7 (July 1, 2020): 773–86. https://doi.org/10.1001/jamacardio.2020.0822.
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  - Tomazini, Bruno Martins, Israel Silva Maia, Flavia Regina Bueno, Maria Vitoria Aparecida Oliveira Silva, Franca Pellison Baldassare, Eduardo Leite Vieira Costa, Ricardo Antonio Bonifácio Moura, et al. “COVID-19-associated ARDS treated with DEXamethasone (CoDEX): study design and rationale for a randomized trial.” Rev Bras Ter Intensiva 32, no. 3 (July 2020): 354–62. https://doi.org/10.5935/0103-507X.20200063.
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  - Drager, Luciano F., Andrea Pio-Abreu, Renato D. Lopes, and Luiz A. Bortolotto. “Is Hypertension a Real Risk Factor for Poor Prognosis in the COVID-19 Pandemic?” Curr Hypertens Rep 22, no. 6 (June 13, 2020): 43. https://doi.org/10.1007/s11906-020-01057-x.
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  - Lopes, Renato D., and Alexander C. Fanaroff. “Dropping P2Y₁₂ inhibitors in patients with AF undergoing PCI? Not yet a SAFE bet.” Eurointervention 16, no. 2 (June 12, 2020): e109–11. https://doi.org/10.4244/EIJV16I2A18.
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  - Avila, André d’, Marco F Vidal Melo, and Renato D. Lopes. “Pandemonium During the Pandemic: What is the Role of Health and Science Professionals?” Arq Bras Cardiol 114, no. 5 (June 1, 2020): 753–54. https://doi.org/10.36660/abc.20200320.
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  - Diepen, Sean van, Rajendra H. Mehta, Jeffrey D. Leimberger, Shaun G. Goodman, Stephen Fremes, Rachael Jankowich, Matthias Heringlake, et al. “Levosimendan in patients with reduced left ventricular function undergoing isolated coronary or valve surgery.” J Thorac Cardiovasc Surg 159, no. 6 (June 2020): 2302-2309.e6. https://doi.org/10.1016/j.jtcvs.2019.06.020.
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  - Guimarães, Patrícia O., Márcio C. Sampaio, Felipe L. Malafaia, Renato D. Lopes, Alexander C. Fanaroff, Pedro G. M. de Barros E Silva, Tiago Mendonça Dos Santos, et al. “Clinical outcomes and need for intensive care after non-ST-segment-elevation myocardial infarction.” Eur J Intern Med 76 (June 2020): 58–63. https://doi.org/10.1016/j.ejim.2020.02.008.
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  - Alexander, John H., Daniel Wojdyla, Amit N. Vora, Laine Thomas, Christopher B. Granger, Shaun G. Goodman, Ronald Aronson, Stephan Windecker, Roxana Mehran, and Renato D. Lopes. “Risk/Benefit Tradeoff of Antithrombotic Therapy in Patients With Atrial Fibrillation Early and Late After an Acute Coronary Syndrome or Percutaneous Coronary Intervention: Insights From AUGUSTUS.” Circulation 141, no. 20 (May 19, 2020): 1618–27. https://doi.org/10.1161/CIRCULATIONAHA.120.046534.
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  - Lopes, Renato D., Ariane Vieira Scarlatelli Macedo, Pedro Gabriel Melo de Barros E Silva, Renata Junqueira Moll-Bernardes, Andre Feldman, Guilherme D’Andréa Saba Arruda, Andrea Silvestre de Souza, et al. “Continuing versus suspending angiotensin-converting enzyme inhibitors and angiotensin receptor blockers: Impact on adverse outcomes in hospitalized patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).” Am Heart J, May 13, 2020. https://doi.org/10.1016/j.ahj.2020.05.002.
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  - Bhatt, Deepak L., Andrew H. Briggs, Shelby D. Reed, Lieven Annemans, Michael Szarek, Vera A. Bittner, Rafael Diaz, et al. “Cost-Effectiveness of Alirocumab in Patients With Acute Coronary Syndromes: The ODYSSEY OUTCOMES Trial.” J Am Coll Cardiol 75, no. 18 (May 12, 2020): 2297–2308. https://doi.org/10.1016/j.jacc.2020.03.029.
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  - Lopes, Renato D., Hwanhee Hong, Ralf E. Harskamp, Deepak L. Bhatt, Roxana Mehran, Christopher P. Cannon, Christopher B. Granger, et al. “Optimal Antithrombotic Regimens for Patients With Atrial Fibrillation Undergoing Percutaneous Coronary Intervention: An Updated Network Meta-analysis.” Jama Cardiol 5, no. 5 (May 1, 2020): 582–89. https://doi.org/10.1001/jamacardio.2019.6175.
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  - Torp-Pedersen, Christian, Andreas Goette, Peter Bronnum Nielsen, Tatjana Potpara, Laurent Fauchier, Alan John Camm, Elena Arbelo, et al. “'Real-world' observational studies in arrhythmia research: data sources, methodology, and interpretation. A position document from European Heart Rhythm Association (EHRA), endorsed by Heart Rhythm Society (HRS), Asia-Pacific HRS (APHRS), and Latin America HRS (LAHRS).” Europace 22, no. 5 (May 1, 2020): 831–32. https://doi.org/10.1093/europace/euz210.
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  - Stanifer, John W., Sean D. Pokorney, Glenn M. Chertow, Stefan H. Hohnloser, Daniel M. Wojdyla, Samira Garonzik, Wonkyung Byon, et al. “Apixaban Versus Warfarin in Patients With Atrial Fibrillation and Advanced Chronic Kidney Disease.” Circulation 141, no. 17 (April 28, 2020): 1384–92. https://doi.org/10.1161/CIRCULATIONAHA.119.044059.
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  - Flumignan, R. L. G., V. F. M. Trevisani, R. D. Lopes, J. C. C. Baptista-Silva, C. D. Q. Flumignan, and L. C. U. Nakano. “Ultrasound guidance for arterial (other than femoral) catheterisation in adults.” Cochrane Database of Systematic Reviews 2020, no. 4 (April 17, 2020). https://doi.org/10.1002/14651858.CD013585.
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  - Fanaroff, Alexander C., Ghazala Haque, Betsy Thomas, Allegra E. Stone, Lynn M. Perkins, Matthew Wilson, W Schuyler Jones, et al. “Methods for safety and endpoint ascertainment: identification of adverse events through scrutiny of negatively adjudicated events.” Trials 21, no. 1 (April 9, 2020): 323. https://doi.org/10.1186/s13063-020-04254-w.
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  - Maron, David J., Judith S. Hochman, Harmony R. Reynolds, Sripal Bangalore, Sean M. O’Brien, William E. Boden, Bernard R. Chaitman, et al. “Initial Invasive or Conservative Strategy for Stable Coronary Disease.” N Engl J Med 382, no. 15 (April 9, 2020): 1395–1407. https://doi.org/10.1056/NEJMoa1915922.
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  - Lopes, Renato D., Claudio Gimpelewicz, and John J. V. McMurray. “Chagas disease: still a neglected emergency?” Lancet 395, no. 10230 (April 4, 2020): 1113–14. https://doi.org/10.1016/S0140-6736(20)30171-9.
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  - Capodanno, Davide, Deepak L. Bhatt, John W. Eikelboom, Keith A. A. Fox, Tobias Geisler, C. Michael Gibson, Jose Ramon Gonzalez-Juanatey, et al. “Dual-pathway inhibition for secondary and tertiary antithrombotic prevention in cardiovascular disease.” Nat Rev Cardiol 17, no. 4 (April 2020): 242–57. https://doi.org/10.1038/s41569-019-0314-y.
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  - Zeitouni, Michel, Anna Giczewska, Renato D. Lopes, Daniel M. Wojdyla, Christina Christersson, Agneta Siegbahn, Raffaele De Caterina, et al. “Clinical and Pharmacological Effects of Apixaban Dose Adjustment in the ARISTOTLE Trial.” J Am Coll Cardiol 75, no. 10 (March 17, 2020): 1145–55. https://doi.org/10.1016/j.jacc.2019.12.060.
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  - Lopes, Renato D., Sergio Leonardi, Daniel M. Wojdyla, Amit N. Vora, Laine Thomas, Robert F. Storey, Dragos Vinereanu, et al. “Stent Thrombosis in Patients With Atrial Fibrillation Undergoing Coronary Stenting in the AUGUSTUS Trial.” Circulation 141, no. 9 (March 3, 2020): 781–83. https://doi.org/10.1161/CIRCULATIONAHA.119.044584.
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  - Bahit, M Cecilia, Christopher B. Granger, John H. Alexander, Hillary Mulder, Daniel M. Wojdyla, Michael Hanna, Shinya Goto, et al. “Regional variation in clinical characteristics and outcomes in patients with atrial fibrillation: Findings from the ARISTOTLE trial.” Int J Cardiol 302 (March 1, 2020): 53–58. https://doi.org/10.1016/j.ijcard.2019.12.060.
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  - Garcia, David A., Deborah A. Fisher, Hillary Mulder, Lisa Wruck, Raffele De Caterina, Sigrun Halvorsen, Christopher B. Granger, et al. “Gastrointestinal bleeding in patients with atrial fibrillation treated with Apixaban or warfarin: Insights from the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) trial.” Am Heart J 221 (March 2020): 1–8. https://doi.org/10.1016/j.ahj.2019.10.013.
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  - Pandey, Arjun K., Ke Xu, Li Zhang, Saurabh Gupta, John Eikelboom, Olivia Cook, William F. McIntyre, et al. “Lower versus Standard INR Targets in Atrial Fibrillation: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.” Thromb Haemost 120, no. 3 (March 2020): 484–94. https://doi.org/10.1055/s-0039-3401823.
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  - Lopes, Renato D., Pedro G. M. de Barros E Silva, Lucas Petri Damiani, Renato Hideo Nakagawa Santos, John H. Alexander, Christopher B. Granger, and Otavio Berwanger. “Major Adverse Cardiovascular Events After 12 Months Among Patients With Acute Coronary Syndrome Receiving Loading Doses of Atorvastatin Prior to Planned PCI.” Jama 323, no. 8 (February 25, 2020): 787–89. https://doi.org/10.1001/jama.2020.0118.
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  - Ageno, Walter, Renato D. Lopes, Megan K. Yee, Adrian Hernandez, Russell Hull, Samuel Z. Goldhaber, C Michael Gibson, and Alexander T. Cohen. “Extended prophylaxis of venous thromboembolism with betrixaban in acutely ill medical patients with and without cancer: insights from the APEX trial.” J Thromb Thrombolysis 49, no. 2 (February 2020): 214–19. https://doi.org/10.1007/s11239-019-01943-5.
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  - Bethel, M Angelyn, Robert J. Mentz, Peter Merrill, John B. Buse, Juliana C. Chan, Shaun G. Goodman, Nayyar Iqbal, et al. “Microvascular and Cardiovascular Outcomes According to Renal Function in Patients Treated With Once-Weekly Exenatide: Insights From the EXSCEL Trial.” Diabetes Care 43, no. 2 (February 2020): 446–52. https://doi.org/10.2337/dc19-1065.
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  - Santos, Eduardo Cavalcanti Lapa, J. M. Del Castillo, G. B. O. Parente, R. P. Pedrosa, P. S. Gadelha, R. D. Lopes, F. Kreimer, and F. R. M. Neto. “Changes in Left Ventricular Mechanics After Sleeve Gastrectomy.” Obes Surg 30, no. 2 (February 2020): 580–86. https://doi.org/10.1007/s11695-019-04216-5.
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  - Dalgaard, Frederik, Hillary Mulder, Daniel M. Wojdyla, Renato D. Lopes, Claes Held, John H. Alexander, Raffaele De Caterina, et al. “Patients With Atrial Fibrillation Taking Nonsteroidal Anti-Inflammatory Drugs and Oral Anticoagulants in the ARISTOTLE Trial.” Circulation 141, no. 1 (January 7, 2020): 10–20. https://doi.org/10.1161/CIRCULATIONAHA.119.041296.
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  - Harskamp, Ralf E., John H. Alexander, and Renato D. Lopes. “Clinical Considerations Prior to Transition From Triple Antithrombotic Therapy to Dual Antithrombotic Therapy-Reply.” Jama Cardiol 5, no. 1 (January 1, 2020): 111–12. https://doi.org/10.1001/jamacardio.2019.4551.
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  - Lobo, Marcelo G., Marcia M. Schmidt, Renato D. Lopes, Thiago Dipp, Ivan P. Feijó, Karine E. S. Schmidt, Cristina A. Gazeta, et al. “Treating periodontal disease in patients with myocardial infarction: A randomized clinical trial.” Eur J Intern Med 71 (January 2020): 76–80. https://doi.org/10.1016/j.ejim.2019.08.012.
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  - Ramacciotti, Eduardo, Ariane Scarlatelli Macedo, Rodrigo Bruno Biagioni, Roberto Augusto Caffaro, Renato Delascio Lopes, João Carlos Guerra, Fernanda Andrade Orsi, et al. “Evidence-Based Practical Guidance for the Antithrombotic Management in Patients With Coronavirus Disease (COVID-19) in 2020.” Clin Appl Thromb Hemost 26 (January 2020): 1076029620936350. https://doi.org/10.1177/1076029620936350.
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  - Lopes, Renato D., Hwanhee Hong, and John H. Alexander. “Antithrombotic therapy after acute coronary syndrome and/or percutaneous coronary intervention in atrial fibrillation: finding the sweet spot.” Eur Heart J 40, no. 46 (December 7, 2019): 3768–70. https://doi.org/10.1093/eurheartj/ehz823.
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  - Vora, Amit N., John H. Alexander, Daniel M. Wojdyla, Ronald Aronson, Christopher B. Granger, Harald Darius, Stephan Windecker, et al. “Hospitalization Among Patients With Atrial Fibrillation and a Recent Acute Coronary Syndrome or Percutaneous Coronary Intervention Treated With Apixaban or Aspirin: Insights From the AUGUSTUS Trial.” Circulation 140, no. 23 (December 3, 2019): 1960–63. https://doi.org/10.1161/CIRCULATIONAHA.119.043754.
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  - Windecker, Stephan, Renato D. Lopes, Tyler Massaro, Charlotte Jones-Burton, Christopher B. Granger, Ronald Aronson, Gretchen Heizer, et al. “Antithrombotic Therapy in Patients With Atrial Fibrillation and Acute Coronary Syndrome Treated Medically or With Percutaneous Coronary Intervention or Undergoing Elective Percutaneous Coronary Intervention: Insights From the AUGUSTUS Trial.” Circulation 140, no. 23 (December 3, 2019): 1921–32. https://doi.org/10.1161/CIRCULATIONAHA.119.043308.
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  - Ageno, Walter, Renato D. Lopes, Megan K. Yee, Adrian Hernandez, Russell D. Hull, Samuel Z. Goldhaber, C Michael Gibson, and Alexander T. Cohen. “Net-clinical benefit of extended prophylaxis of venous thromboembolism with betrixaban in medically ill patients aged 80 or more.” J Thromb Haemost 17, no. 12 (December 2019): 2089–98. https://doi.org/10.1111/jth.14600.
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  - Bhatt, Ankeet S., Nancy Luo, Nicole Solomon, Neha J. Pagidipati, Giuseppe Ambrosio, Jennifer B. Green, Darren K. McGuire, et al. “International variation in characteristics and clinical outcomes of patients with type 2 diabetes and heart failure: Insights from TECOS.” Am Heart J 218 (December 2019): 57–65. https://doi.org/10.1016/j.ahj.2019.08.016.
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  - Boriani, Giuseppe, Jeff S. Healey, Renate B. Schnabel, Renato D. Lopes, Hugh Calkins, John A. Camm, and Ben Freedman. “Oral anticoagulation for subclinical atrial tachyarrhythmias detected by implantable cardiac devices: an international survey of the AF-SCREEN Group.” Int J Cardiol 296 (December 1, 2019): 65–70. https://doi.org/10.1016/j.ijcard.2019.07.039.
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  - Brennan, J Matthew, Lisa Wruck, Michael J. Pencina, Robert M. Clare, Renato D. Lopes, John H. Alexander, Sean O’Brien, et al. “Claims-based cardiovascular outcome identification for clinical research: Results from 7 large randomized cardiovascular clinical trials.” Am Heart J 218 (December 2019): 110–22. https://doi.org/10.1016/j.ahj.2019.09.002.
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  - Malafaia, Felipe L., Patrícia O. Guimarães, Márcio C. Sampaio, Pedro G. M. de Barros E Silva, Renato D. Lopes, Juliano V. Custódio, Miguel da S Diniz, José C. T. Garcia, and Valter Furlan. “Electrical cardioversion for supraventricular arrhythmias in octagenarians.” J Geriatr Cardiol 16, no. 12 (December 2019): 902–4. https://doi.org/10.11909/j.issn.1671-5411.2019.12.009.
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  - Fudim, Marat, Jennifer White, Neha J. Pagidipati, Yuliya Lokhnygina, Julio Wainstein, Jan Murin, Nayyar Iqbal, et al. “Effect of Once-Weekly Exenatide in Patients With Type 2 Diabetes Mellitus With and Without Heart Failure and Heart Failure-Related Outcomes: Insights From the EXSCEL Trial.” Circulation 140, no. 20 (November 12, 2019): 1613–22. https://doi.org/10.1161/CIRCULATIONAHA.119.041659.
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  - Roe, Matthew T., Qian H. Li, Deepak L. Bhatt, Vera A. Bittner, Rafael Diaz, Shaun G. Goodman, Robert A. Harrington, et al. “Risk Categorization Using New American College of Cardiology/American Heart Association Guidelines for Cholesterol Management and Its Relation to Alirocumab Treatment Following Acute Coronary Syndromes.” Circulation 140, no. 19 (November 5, 2019): 1578–89. https://doi.org/10.1161/CIRCULATIONAHA.119.042551.
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  - Goldstein, Sarah A., Jennifer Green, Kurt Huber, Daniel M. Wojdyla, Renato D. Lopes, John H. Alexander, Dragos Vinereanu, Lars Wallentin, Christopher B. Granger, and Sana M. Al-Khatib. “Characteristics and Outcomes of Atrial Fibrillation in Patients With Thyroid Disease (from the ARISTOTLE Trial).” Am J Cardiol 124, no. 9 (November 1, 2019): 1406–12. https://doi.org/10.1016/j.amjcard.2019.07.046.
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  - Harskamp, Ralf E., Martina Teichert, Wim A. M. Lucassen, Henk C. P. M. van Weert, and Renato D. Lopes. “Impact of Polypharmacy and P-Glycoprotein- and CYP3A4-Modulating Drugs on Safety and Efficacy of Oral Anticoagulation Therapy in Patients with Atrial Fibrillation.” Cardiovasc Drugs Ther 33, no. 5 (October 2019): 615–23. https://doi.org/10.1007/s10557-019-06907-8.
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  - Pagidipati, Neha J., and Renato D. Lopes. “New antihyperglycemic medications with cardiovascular protection for patients with diabetes: What do surgeons need to know?” J Thorac Cardiovasc Surg 158, no. 4 (October 2019): 1113–17. https://doi.org/10.1016/j.jtcvs.2019.03.140.
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  - Wang, Alice, Zhuokai Li, Jennifer A. Rymer, Andrzej S. Kosinski, Babatunde Yerokun, Morgan L. Cox, Brian C. Gulack, et al. “Relation of Postdischarge Care Fragmentation and Outcomes in Transcatheter Aortic Valve Implantation from the STS/ACC TVT Registry.” Am J Cardiol 124, no. 6 (September 15, 2019): 912–19. https://doi.org/10.1016/j.amjcard.2019.06.005.
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  - Moraes, Eraldo Ribeiro Ferreira Leão de, Cláudio Cirenza, Renato D. Lopes, Antônio Carlos Carvalho, Patricia O. Guimaraes, Alfredo Augusto Eyer Rodrigues, and Angelo Amato Vincenzo de Paola. “Prevalence of atrial fibrillation and stroke risk assessment based on telemedicine screening tools in a primary healthcare setting.” Eur J Intern Med 67 (September 2019): 36–41. https://doi.org/10.1016/j.ejim.2019.04.024.
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  - Sharma, Abhinav, Emil Hagström, Daniel M. Wojdyla, Megan L. Neely, Robert A. Harrington, Lars Wallentin, John H. Alexander, Shaun G. Goodman, Renato D. Lopes, and Renato D. Apixaban for Prevention of Acute Ischemic Safety Events APPRAISE-2 Steering Committee and Investigators. “Clinical consequences of bleeding among individuals with a recent acute coronary syndrome: Insights from the APPRAISE-2 trial.” Am Heart J 215 (September 2019): 106–13. https://doi.org/10.1016/j.ahj.2019.05.004.
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  - White, Harvey D., Ph Gabriel Steg, Michael Szarek, Deepak L. Bhatt, Vera A. Bittner, Rafael Diaz, Jay M. Edelberg, et al. “Effects of alirocumab on types of myocardial infarction: insights from the ODYSSEY OUTCOMES trial.” Eur Heart J 40, no. 33 (September 1, 2019): 2801–9. https://doi.org/10.1093/eurheartj/ehz299.
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  - “Department of Error.” The Lancet 394, no. 10202 (September 2019): 918–918. https://doi.org/10.1016/s0140-6736(19)32102-6.
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  - Guimarães, Patrícia O., Eric D. Peterson, Susanna R. Stevens, Yuliya Lokhnygina, Jennifer B. Green, Darren K. McGuire, Rury R. Holman, and Renato D. Lopes. “Antithrombotic treatment gap among patients with atrial fibrillation and type 2 diabetes.” Int J Cardiol 289 (August 15, 2019): 58–62. https://doi.org/10.1016/j.ijcard.2019.04.085.
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  - Lopes, Renato D., Hwanhee Hong, Ralf E. Harskamp, Deepak L. Bhatt, Roxana Mehran, Christopher P. Cannon, Christopher B. Granger, et al. “Safety and Efficacy of Antithrombotic Strategies in Patients With Atrial Fibrillation Undergoing Percutaneous Coronary Intervention: A Network Meta-analysis of Randomized Controlled Trials.” Jama Cardiol 4, no. 8 (August 1, 2019): 747–55. https://doi.org/10.1001/jamacardio.2019.1880.
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  - Ray, Kausik K., Helen M. Colhoun, Michael Szarek, Marie Baccara-Dinet, Deepak L. Bhatt, Vera A. Bittner, Andrzej J. Budaj, et al. “Effects of alirocumab on cardiovascular and metabolic outcomes after acute coronary syndrome in patients with or without diabetes: a prespecified analysis of the ODYSSEY OUTCOMES randomised controlled trial.” Lancet Diabetes Endocrinol 7, no. 8 (August 2019): 618–28. https://doi.org/10.1016/S2213-8587(19)30158-5.
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  - Capodanno, Davide, Kurt Huber, Roxana Mehran, Gregory Y. H. Lip, David P. Faxon, Christopher B. Granger, Pascal Vranckx, et al. “Management of Antithrombotic Therapy in Atrial Fibrillation Patients Undergoing PCI: JACC State-of-the-Art Review.” J Am Coll Cardiol 74, no. 1 (July 9, 2019): 83–99. https://doi.org/10.1016/j.jacc.2019.05.016.
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  - Guimarães, Patricia O., Renato D. Lopes, John H. Alexander, Laine Thomas, Anne S. Hellkamp, Ziad Hijazi, Elaine M. Hylek, et al. “International normalized ratio control and subsequent clinical outcomes in patients with atrial fibrillation using warfarin.” J Thromb Thrombolysis 48, no. 1 (July 2019): 27–34. https://doi.org/10.1007/s11239-019-01858-1.
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  - Harskamp, Ralf E., John H. Alexander, and Renato D. Lopes. “Navigating the treacherous waters of antithrombotic therapies in patients with atrial fibrillation and coronary artery disease: Lessons from AUGUSTUS.” Eur J Intern Med 65 (July 2019): 4–5. https://doi.org/10.1016/j.ejim.2019.05.018.
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  - Olivier, Christoph B., Deepak L. Bhatt, Sergio Leonardi, Gregg W. Stone, C Michael Gibson, Ph Gabriel Steg, Christian W. Hamm, et al. “Central Adjudication Identified Additional and Prognostically Important Myocardial Infarctions in Patients Undergoing Percutaneous Coronary Intervention.” Circ Cardiovasc Interv 12, no. 7 (July 2019): e007342. https://doi.org/10.1161/CIRCINTERVENTIONS.118.007342.
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  - Åkerblom, Axel, Daniel M. Wojdyla, Lars Wallentin, Stefan K. James, Flávio de Souza Brito, Philippe Gabriel Steg, Christopher P. Cannon, et al. “Ticagrelor in patients with heart failure after acute coronary syndromes-Insights from the PLATelet inhibition and patient Outcomes (PLATO) trial.” Am Heart J 213 (July 2019): 57–65. https://doi.org/10.1016/j.ahj.2019.04.006.
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  - Berwanger, Otavio, Renato D. Lopes, Diogo D. F. Moia, Francisco A. Fonseca, Lixin Jiang, Shaun G. Goodman, Stephen J. Nicholls, et al. “Ticagrelor Versus Clopidogrel in Patients With STEMI Treated With Fibrinolysis: TREAT Trial.” J Am Coll Cardiol 73, no. 22 (June 11, 2019): 2819–28. https://doi.org/10.1016/j.jacc.2019.03.011.
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  - Pokorney, Sean D., and Renato D. Lopes. “Atrial fibrillation: what do we know about screening and what do we not know about treatment?” Heart 105, no. 11 (June 2019): 817–19. https://doi.org/10.1136/heartjnl-2018-314518.
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  - Hohnloser, Stefan H., Marat Fudim, John H. Alexander, Daniel M. Wojdyla, Justin A. Ezekowitz, Michael Hanna, Dan Atar, et al. “Efficacy and Safety of Apixaban Versus Warfarin in Patients With Atrial Fibrillation and Extremes in Body Weight.” Circulation 139, no. 20 (May 14, 2019): 2292–2300. https://doi.org/10.1161/CIRCULATIONAHA.118.037955.
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  - Wang, Kang-Ling, Renato D. Lopes, Manesh R. Patel, Harry R. Büller, Doreen Su-Yin Tan, Chern-En Chiang, and Robert P. Giugliano. “Efficacy and safety of reduced-dose non-vitamin K antagonist oral anticoagulants in patients with atrial fibrillation: a meta-analysis of randomized controlled trials.” Eur Heart J 40, no. 19 (May 14, 2019): 1492–1500. https://doi.org/10.1093/eurheartj/ehy802.
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  - Spitzer, Ernest, Eugene McFadden, Pascal Vranckx, Hector M. Garcia-Garcia, Jonathan H. Seltzer, Claes Held, Ton de Vries, et al. “Critical Appraisal of Contemporary Clinical Endpoint Definitions in Coronary Intervention Trials: A Guidance Document.” Jacc Cardiovasc Interv 12, no. 9 (May 13, 2019): 805–19. https://doi.org/10.1016/j.jcin.2018.12.031.
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  - Machline-Carrion, M Julia, Eliana Vieira Santucci, Lucas Petri Damiani, M Cecilia Bahit, Germán Málaga, Octávio Marques Pontes-Neto, Sheila Cristina Ouriques Martins, et al. “Effect of a Quality Improvement Intervention on Adherence to Therapies for Patients With Acute Ischemic Stroke and Transient Ischemic Attack: A Cluster Randomized Clinical Trial.” Jama Neurol, May 6, 2019. https://doi.org/10.1001/jamaneurol.2019.1012.
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  - Guimarães, Patricia O., Sean D. Pokorney, Renato D. Lopes, Daniel M. Wojdyla, Bernard J. Gersh, Anna Giczewska, Anthony Carnicelli, et al. “Efficacy and safety of apixaban vs warfarin in patients with atrial fibrillation and prior bioprosthetic valve replacement or valve repair: Insights from the ARISTOTLE trial.” Clin Cardiol 42, no. 5 (May 2019): 568–71. https://doi.org/10.1002/clc.23178.
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  - Harskamp, Ralf E., Thomas M. Granger, Robert M. Clare, Kyle R. White, Renato D. Lopes, Karen S. Pieper, Christopher B. Granger, Christopher B. Newgard, Svati H. Shah, and L Kristin Newby. “Peripheral blood metabolite profiles associated with new onset atrial fibrillation.” Am Heart J 211 (May 2019): 54–59. https://doi.org/10.1016/j.ahj.2019.01.010.
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  - Machline-Carrion, M Julia, Rafael Marques Soares, Lucas Petri Damiani, Viviane Bezerra Campos, Bruna Sampaio, Francisco H. Fonseca, Maria Cristina Izar, et al. “Effect of a Multifaceted Quality Improvement Intervention on the Prescription of Evidence-Based Treatment in Patients at High Cardiovascular Risk in Brazil: The BRIDGE Cardiovascular Prevention Cluster Randomized Clinical Trial.” Jama Cardiol 4, no. 5 (May 1, 2019): 408–17. https://doi.org/10.1001/jamacardio.2019.0649.
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  - Lopes, Renato D., Gretchen Heizer, Ronald Aronson, Amit N. Vora, Tyler Massaro, Roxana Mehran, Shaun G. Goodman, et al. “Antithrombotic Therapy after Acute Coronary Syndrome or PCI in Atrial Fibrillation.” N Engl J Med 380, no. 16 (April 18, 2019): 1509–24. https://doi.org/10.1056/NEJMoa1817083.
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  - Washam, Jeffrey B., Stefan H. Hohnloser, Renato D. Lopes, Daniel M. Wojdyla, Dragos Vinereanu, John H. Alexander, Bernard J. Gersh, et al. “Interacting medication use and the treatment effects of apixaban versus warfarin: results from the ARISTOTLE Trial.” J Thromb Thrombolysis 47, no. 3 (April 2019): 345–52. https://doi.org/10.1007/s11239-019-01823-y.
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  - Fanaroff, Alexander C., Robert M. Califf, Stephan Windecker, Sidney C. Smith, and Renato D. Lopes. “Levels of Evidence Supporting American College of Cardiology/American Heart Association and European Society of Cardiology Guidelines, 2008-2018.” Jama 321, no. 11 (March 19, 2019): 1069–80. https://doi.org/10.1001/jama.2019.1122.
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  - Hochman, Judith S., Harmony R. Reynolds, Sripal Bangalore, Sean M. O’Brien, Karen P. Alexander, Roxy Senior, William E. Boden, et al. “Baseline Characteristics and Risk Profiles of Participants in the ISCHEMIA Randomized Clinical Trial.” Jama Cardiol 4, no. 3 (March 1, 2019): 273–86. https://doi.org/10.1001/jamacardio.2019.0014.
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  - Ranney, David N., Judson B. Williams, Hillary Mulder, Daniel Wojdyla, Morgan L. Cox, C Michael Gibson, Michael J. Mack, Mani A. Daneshmand, John H. Alexander, and Renato D. Lopes. “Comparison of Outcomes and Frequency of Graft Failure With Use of Free Versus In Situ Internal Mammary Artery Bypass Conduits (from the PREVENT IV Trial).” Am J Cardiol 123, no. 4 (February 15, 2019): 571–75. https://doi.org/10.1016/j.amjcard.2018.11.029.
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  - Fanaroff, Alexander C., Robert Clare, Karen S. Pieper, Kenneth W. Mahaffey, Chiara Melloni, Jennifer B. Green, John H. Alexander, et al. “Frequency, Regional Variation, and Predictors of Undetermined Cause of Death in Cardiometabolic Clinical Trials: A Pooled Analysis of 9259 Deaths in 9 Trials.” Circulation 139, no. 7 (February 12, 2019): 863–73. https://doi.org/10.1161/CIRCULATIONAHA.118.037202.
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  - Goto, Shinya, Pantep Angchaisuksiri, Jean-Pierre Bassand, A John Camm, Helena Dominguez, Laura Illingworth, Harry Gibbs, et al. “Management and 1-Year Outcomes of Patients With Newly Diagnosed Atrial Fibrillation and Chronic Kidney Disease: Results From the Prospective GARFIELD - AF Registry.” J Am Heart Assoc 8, no. 3 (February 5, 2019): e010510. https://doi.org/10.1161/JAHA.118.010510.
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  - Szarek, Michael, Harvey D. White, Gregory G. Schwartz, Marco Alings, Deepak L. Bhatt, Vera A. Bittner, Chern-En Chiang, et al. “Alirocumab Reduces Total Nonfatal Cardiovascular and Fatal Events: The ODYSSEY OUTCOMES Trial.” J Am Coll Cardiol 73, no. 4 (February 5, 2019): 387–96. https://doi.org/10.1016/j.jacc.2018.10.039.
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  - Van der Wall, Sake J., Renato D. Lopes, James Aisenberg, Paul Reilly, Joanne van Ryn, Stephan Glund, Amelie Elsaesser, Frederikus A. Klok, Charles V. Pollack, and Menno V. Huisman. “Idarucizumab for Dabigatran Reversal in the Management of Patients With Gastrointestinal Bleeding.” Circulation 139, no. 6 (February 5, 2019): 748–56. https://doi.org/10.1161/CIRCULATIONAHA.118.036710.
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  - Alexander, Karen P., Marc A. Brouwer, Hillary Mulder, Dragos Vinereanu, Renato D. Lopes, Marco Proietti, Sana M. Al-Khatib, et al. “Outcomes of apixaban versus warfarin in patients with atrial fibrillation and multi-morbidity: Insights from the ARISTOTLE trial.” Am Heart J 208 (February 2019): 123–31. https://doi.org/10.1016/j.ahj.2018.09.017.
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  - Christersson, Christina, Lars Wallentin, Ulrika Andersson, John H. Alexander, Marco Alings, Raffaele De Caterina, Bernard J. Gersh, et al. “Effect of apixaban compared with warfarin on coagulation markers in atrial fibrillation.” Heart 105, no. 3 (February 2019): 235–42. https://doi.org/10.1136/heartjnl-2018-313351.
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  - Held, Claes, Harvey D. White, Ralph A. H. Stewart, Richard Davies, Shani Sampson, Karen Chiswell, Adam Silverstein, et al. “Characterization of cardiovascular clinical events and impact of event adjudication on the treatment effect of darapladib versus placebo in patients with stable coronary heart disease: Insights from the STABILITY trial.” Am Heart J 208 (February 2019): 65–73. https://doi.org/10.1016/j.ahj.2018.10.010.
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  - Guimarães, Patrícia O., Pearl Zakroysky, Abhinav Goyal, Renato D. Lopes, Lisa A. Kaltenbach, and Tracy Y. Wang. “Usefulness of Antithrombotic Therapy in Patients With Atrial Fibrillation and Acute Myocardial Infarction.” Am J Cardiol 123, no. 1 (January 1, 2019): 12–18. https://doi.org/10.1016/j.amjcard.2018.09.031.
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  - Machline-Carrion, Maria Julia, Eliana Vieira Santucci, Lucas Petri Damiani, Cecilia Bahit, Germán Málaga, Octávio Marques Pontes-Neto, Sheila Cristina Ouriques Martins, et al. “An international cluster-randomized quality improvement trial to increase the adherence to evidence-based therapies for acute ischemic stroke and transient ischemic attack patients: Rationale and design of the BRIDGE STROKE Trial.” Am Heart J 207 (January 2019): 49–57. https://doi.org/10.1016/j.ahj.2018.09.009.
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  - Machline-Carrion, Maria Julia, Rafael Marques Soares, Lucas Petri Damiani, Viviane Bezerra Campos, Bruna Sampaio, Juliana Yamashita, Francisco H. Fonseca, et al. “Rationale and design for a cluster randomized quality-improvement trial to increase the uptake of evidence-based therapies for patients at high cardiovascular risk: The BRIDGE-Cardiovascular Prevention trial.” Am Heart J 207 (January 2019): 40–48. https://doi.org/10.1016/j.ahj.2018.10.001.
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  - Ramacciotti, Eduardo, Leandro B. Agati, Roberto Augusto Caffaro, Giuliano G. Volpiani, Renato D. Lopes, Anthony J. Comerota, and Jawed Fareed. “Direct Oral Anticoagulants and Cancer-Associated Thrombosis Management. Where Do We Stand in 2019?” Clin Appl Thromb Hemost 25 (January 2019): 1076029619856433. https://doi.org/10.1177/1076029619856433.
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  - Ramacciotti, Eduardo, Leandro B. Agati, Valéria C. R. Aguiar, Nelson Wolosker, João C. Guerra, Roque P. de Almeida, Juliana Cardoso Alves, et al. “Zika and Chikungunya Virus and Risk for Venous Thromboembolism.” Clin Appl Thromb Hemost 25 (January 2019): 1076029618821184. https://doi.org/10.1177/1076029618821184.
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  - Tallo, Fernando Sabia, Simone de Campos Vieira Abib, Andre Luciano Baitello, and Renato Delascio Lopes. “Development and validation of a questionnaire to assess the knowledge of mechanical ventilation in urgent care among students in their last-year medical course in Brazil.” Clinics (Sao Paulo) 74 (2019): e663. https://doi.org/10.6061/clinics/2019/e663.
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  - Vamos, Mate, Julia Wiebke Erath, Alexander Philipp Benz, Renato Delascio Lopes, and Stefan Hans Hohnloser. “Meta-Analysis of Effects of Digoxin on Survival in Patients with Atrial Fibrillation or Heart Failure: An Update.” Am J Cardiol 123, no. 1 (January 1, 2019): 69–74. https://doi.org/10.1016/j.amjcard.2018.09.036.
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  - Low Wang, Cecilia C., Juuso I. Blomster, Gretchen Heizer, Jeffrey S. Berger, Iris Baumgartner, F Gerry R. Fowkes, Peter Held, et al. “Cardiovascular and Limb Outcomes in Patients With Diabetes and Peripheral Artery Disease: The EUCLID Trial.” J Am Coll Cardiol 72, no. 25 (December 25, 2018): 3274–84. https://doi.org/10.1016/j.jacc.2018.09.078.
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  - Berger, Jeffrey S., Beth L. Abramson, Renato D. Lopes, Gretchen Heizer, Frank W. Rockhold, Iris Baumgartner, F Gerry R. Fowkes, et al. “Ticagrelor versus clopidogrel in patients with symptomatic peripheral artery disease and prior coronary artery disease: Insights from the EUCLID trial.” Vasc Med 23, no. 6 (December 2018): 523–30. https://doi.org/10.1177/1358863X18775594.
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  - Fanaroff, Alexander C., Derek Cyr, Megan L. Neely, Jeffery Bakal, Harvey D. White, Keith A. A. Fox, Paul W. Armstrong, Renato D. Lopes, E Magnus Ohman, and Matthew T. Roe. “Days Alive and Out of Hospital: Exploring a Patient-Centered, Pragmatic Outcome in a Clinical Trial of Patients With Acute Coronary Syndromes.” Circ Cardiovasc Qual Outcomes 11, no. 12 (December 2018): e004755. https://doi.org/10.1161/CIRCOUTCOMES.118.004755.
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  - Schwartz, Gregory G., P Gabriel Steg, Michael Szarek, Deepak L. Bhatt, Vera A. Bittner, Rafael Diaz, Jay M. Edelberg, et al. “Alirocumab and Cardiovascular Outcomes after Acute Coronary Syndrome.” N Engl J Med 379, no. 22 (November 29, 2018): 2097–2107. https://doi.org/10.1056/NEJMoa1801174.
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  - Lopes, Renato D., Pedro G. M. de Barros E Silva, Isabella de Andrade Jesuíno, Eliana Vieira Santucci, Lilian Mazza Barbosa, Lucas Petri Damiani, Renato Hideo Nakagawa Santos, et al. “Timing of Loading Dose of Atorvastatin in Patients Undergoing Percutaneous Coronary Intervention for Acute Coronary Syndromes: Insights From the SECURE-PCI Randomized Clinical Trial.” Jama Cardiol 3, no. 11 (November 1, 2018): 1113–18. https://doi.org/10.1001/jamacardio.2018.3408.
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  - Lopes, Renato D., Weimar Kunz Sebba Barroso, Andrea Araujo Brandao, Eduardo Costa Duarte Barbosa, Marcus Vinicius Bolivar Malachias, Marco Mota Gomes, Celso Amodeo, et al. “The First Brazilian Registry of Hypertension.” Am Heart J 205 (November 2018): 154–57. https://doi.org/10.1016/j.ahj.2018.08.012.
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  - Olivier, Christoph B., Vandana Sundaram, Deepak L. Bhatt, Sergio Leonardi, Renato D. Lopes, Victoria Y. Ding, Lingyao Yang, et al. “Definitions of peri-procedural myocardial infarction and the association with one-year mortality: Insights from CHAMPION trials.” Int J Cardiol 270 (November 1, 2018): 96–101. https://doi.org/10.1016/j.ijcard.2018.06.034.
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  - Sawhney, Jitendra Ps, Veerappa A. Kothiwale, Vikas Bisne, Rajashekhar Durgaprasad, Praveen Jadhav, Manoj Chopda, Velam Vanajakshamma, et al. “Risk profiles and one-year outcomes of patients with newly diagnosed atrial fibrillation in India: Insights from the GARFIELD-AF Registry.” Indian Heart J 70, no. 6 (November 2018): 828–35. https://doi.org/10.1016/j.ihj.2018.09.001.
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  - Hernandez, Adrian F., Jennifer B. Green, Salim Janmohamed, Ralph B. D’Agostino, Christopher B. Granger, Nigel P. Jones, Lawrence A. Leiter, et al. “Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo-controlled trial.” Lancet 392, no. 10157 (October 27, 2018): 1519–29. https://doi.org/10.1016/S0140-6736(18)32261-X.
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  - Sharma, Abhinav, Ziad Hijazi, Ulrika Andersson, Sana M. Al-Khatib, Renato D. Lopes, John H. Alexander, Claes Held, et al. “Use of Biomarkers to Predict Specific Causes of Death in Patients With Atrial Fibrillation.” Circulation 138, no. 16 (October 16, 2018): 1666–76. https://doi.org/10.1161/CIRCULATIONAHA.118.034125.
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  - Mentz, Robert J., M Angelyn Bethel, Peter Merrill, Yuliya Lokhnygina, John B. Buse, Juliana C. Chan, João S. Felício, et al. “Effect of Once-Weekly Exenatide on Clinical Outcomes According to Baseline Risk in Patients With Type 2 Diabetes Mellitus: Insights From the EXSCEL Trial.” J Am Heart Assoc 7, no. 19 (October 2, 2018): e009304. https://doi.org/10.1161/JAHA.118.009304.
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  - Nazha, Bassel, Bhavi Pandya, Jessica Cohen, Meng Zhang, Renato D. Lopes, David A. Garcia, Matthew W. Sherwood, and Alex C. Spyropoulos. “Periprocedural Outcomes of Direct Oral Anticoagulants Versus Warfarin in Nonvalvular Atrial Fibrillation.” Circulation 138, no. 14 (October 2, 2018): 1402–11. https://doi.org/10.1161/CIRCULATIONAHA.117.031457.
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  - Luo, Nancy, Haolin Xu, Hani Jneid, Gregg C. Fonarow, Renato D. Lopes, Jonathan P. Piccini, Anne B. Curtis, et al. “Use of Oral Anticoagulation in Eligible Patients Discharged With Heart Failure and Atrial Fibrillation.” Circ Heart Fail 11, no. 10 (October 2018): e005356. https://doi.org/10.1161/CIRCHEARTFAILURE.118.005356.
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  - Nicolau, Jose C., Remo H. M. Furtado, Luciano M. Baracioli, Livia M. Lara, Talia F. Dalçóquio, Marco A. Scanavini Junior, César A. C. Pereira, et al. “The Use of Oral Beta-Blockers and Clinical Outcomes in Patients with Non-ST-Segment Elevation Acute Coronary Syndromes: a Long-Term Follow-Up Study.” Cardiovasc Drugs Ther 32, no. 5 (October 2018): 435–42. https://doi.org/10.1007/s10557-018-6818-6.
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  - Spyropoulos, Alex C., Walter Ageno, Gregory W. Albers, C Gregory Elliott, Jonathan L. Halperin, William R. Hiatt, Gregory A. Maynard, et al. “Rivaroxaban for Thromboprophylaxis after Hospitalization for Medical Illness.” N Engl J Med 379, no. 12 (September 20, 2018): 1118–27. https://doi.org/10.1056/NEJMoa1805090.
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  - Barros E Silva, Pedro Gabriel Melo de, Henrique Barbosa Ribeiro, Renato Delascio Lopes, Thiago Andrade Macedo, Fabio Conejo, Antônio Cláudio do Amaral Baruzzi, Mariana Yumi Okada, et al. “Improvement in quality indicators using NCDR® registries: First international experience.” Int J Cardiol 267 (September 15, 2018): 13–15. https://doi.org/10.1016/j.ijcard.2018.05.102.
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  - Vora, Amit N., Dadi Dai, Roland Matsuoka, J Kevin Harrison, G Chad Hughes, Matthew W. Sherwood, Jonathan P. Piccini, et al. “Incidence, Management, and Associated Clinical Outcomes of New-Onset Atrial Fibrillation Following Transcatheter Aortic Valve Replacement: An Analysis From the STS/ACC TVT Registry.” Jacc Cardiovasc Interv 11, no. 17 (September 10, 2018): 1746–56. https://doi.org/10.1016/j.jcin.2018.05.042.
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  - Lopes, Renato D., Jan Steffel, Manuela Di Fusco, Allison Keshishian, Xuemei Luo, Xiaoyan Li, Cristina Masseria, et al. “Effectiveness and Safety of Anticoagulants in Adults with Non-valvular Atrial Fibrillation and Concomitant Coronary/Peripheral Artery Disease.” Am J Med 131, no. 9 (September 2018): 1075-1085.e4. https://doi.org/10.1016/j.amjmed.2018.05.007.
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  - Fanaroff, Alexander C., Jan Steffel, John H. Alexander, Gregory Y. H. Lip, Robert M. Califf, and Renato D. Lopes. “Stroke prevention in atrial fibrillation: re-defining 'real-world data' within the broader data universe.” Eur Heart J 39, no. 32 (August 21, 2018): 2932–41. https://doi.org/10.1093/eurheartj/ehy236.
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  - Horowitz, John D., Raffaele De Caterina, Tamila Heresztyn, John H. Alexander, Ulrika Andersson, Renato D. Lopes, Philippe Gabriel Steg, et al. “Asymmetric and Symmetric Dimethylarginine Predict Outcomes in Patients With Atrial Fibrillation: An ARISTOTLE Substudy.” J Am Coll Cardiol 72, no. 7 (August 14, 2018): 721–33. https://doi.org/10.1016/j.jacc.2018.05.058.
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  - Berwanger, Otavio, Jose C. Nicolau, Antonio C. Carvalho, Lixin Jiang, Shaun Goodman, Stephen J. Nicholls, Alexander Parkhomenko, et al. “Ticagrelor versus clopidogrel after fibrinolytic therapy in patients with ST-elevation myocardial infarction: Rationale and design of the ticagrelor in patients with ST elevation myocardial infarction treated with thrombolysis (TREAT) trial.” Am Heart J 202 (August 2018): 89–96. https://doi.org/10.1016/j.ahj.2018.02.017.
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  - Capodanno, Davide, Roxana Mehran, Marco Valgimigli, Usman Baber, Stephan Windecker, Pascal Vranckx, George Dangas, et al. “Aspirin-free strategies in cardiovascular disease and cardioembolic stroke prevention.” Nat Rev Cardiol 15, no. 8 (August 2018): 480–96. https://doi.org/10.1038/s41569-018-0049-1.
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  - Diepen, Sean van, Dat T. Tran, Justin A. Ezekowitz, David A. Zygun, Jason N. Katz, Renato D. Lopes, L Kristin Newby, Finlay A. McAlister, and Padma Kaul. “The high cost of critical care unit over-utilization for patients with NSTE ACS.” Am Heart J 202 (August 2018): 84–88. https://doi.org/10.1016/j.ahj.2018.05.003.
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  - Vinereanu, Dragos, Alice Wang, Hillary Mulder, Renato D. Lopes, Petr Jansky, Basil S. Lewis, Bernard J. Gersh, et al. “Outcomes in anticoagulated patients with atrial fibrillation and with mitral or aortic valve disease.” Heart 104, no. 15 (August 2018): 1292–99. https://doi.org/10.1136/heartjnl-2017-312272.
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  - Filgueiras Filho, Nivaldo Menezes, Gilson Soares Feitosa Filho, Davi Jorge Fontoura Solla, Felipe Coelho Argôlo, Patrícia Oliveira Guimarães, Ivan de Mattos Paiva Filho, Larissa Gordilho Mutti Carvalho, et al. “Implementation of a Regional Network for ST-Segment-Elevation Myocardial Infarction (STEMI) Care and 30-Day Mortality in a Low- to Middle-Income City in Brazil: Findings From Salvador's STEMI Registry (RESISST).” J Am Heart Assoc 7, no. 14 (July 6, 2018). https://doi.org/10.1161/JAHA.118.008624.
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  - Lopes, Renato D., Roberto Rordorf, Gaetano M. De Ferrari, Sergio Leonardi, and Lars Wallentin. “Reply: Digoxin Use in Atrial Fibrillation: Minimizing and Refining its Use When Still Needed.” J Am Coll Cardiol 72, no. 1 (July 3, 2018): 125–26. https://doi.org/10.1016/j.jacc.2018.04.045.
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  - Correia, Luis C. L., Guilherme B. Barcellos, Vitor Calixto, André Volschan, José A. S. Barreto-Filho, Renato D. Lopes, Anis Rassi, Wendy Levinson, and Angelo A. V. de Paola. “'Choosing Wisely' culture among Brazilian cardiologists.” Int J Qual Health Care 30, no. 6 (July 1, 2018): 437–42. https://doi.org/10.1093/intqhc/mzy028.
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  - Inohara, Taku, Karen Pieper, Daniel M. Wojdyla, Manesh R. Patel, William Schuyler Jones, Pierluigi Tricoci, Kenneth W. Mahaffey, et al. “Incidence, timing, and type of first and recurrent ischemic events in patients with and without peripheral artery disease after an acute coronary syndrome.” Am Heart J 201 (July 2018): 25–32. https://doi.org/10.1016/j.ahj.2018.03.013.
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  - Lehman, E Philip, Patricia A. Cowper, Tiffany C. Randolph, Andrzej S. Kosinski, Renato D. Lopes, and Pamela S. Douglas. “Usefulness and Cost-Effectiveness of Universal Echocardiographic Contrast to Detect Left Ventricular Thrombus in Patients with Heart Failure and Reduced Ejection Fraction.” Am J Cardiol 122, no. 1 (July 1, 2018): 121–28. https://doi.org/10.1016/j.amjcard.2018.03.016.
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  - Rymer, Jennifer A., Michael W. Tempelhof, Robert M. Clare, Karen S. Pieper, Christopher B. Granger, Frans Van de Werf, David J. Moliterno, et al. “Discharge timing and outcomes after uncomplicated non-ST-segment elevation acute myocardial infarction.” Am Heart J 201 (July 2018): 103–10. https://doi.org/10.1016/j.ahj.2018.04.010.
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  - Sposato, Luciano A., and Renato D. Lopes. “Disentangling the risk of atrial fibrillation detected after ischemic stroke (AFDAS): A real challenge in clinical practice.” Int J Cardiol 261 (June 15, 2018): 99–100. https://doi.org/10.1016/j.ijcard.2017.12.008.
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  - Lopes, Renato D., Amit N. Vora, Danny Liaw, Christopher B. Granger, Harald Darius, Shaun G. Goodman, Roxana Mehran, Stephan Windecker, and John H. Alexander. “An open-Label, 2 × 2 factorial, randomized controlled trial to evaluate the safety of apixaban vs. vitamin K antagonist and aspirin vs. placebo in patients with atrial fibrillation and acute coronary syndrome and/or percutaneous coronary intervention: Rationale and design of the AUGUSTUS trial.” Am Heart J 200 (June 2018): 17–23. https://doi.org/10.1016/j.ahj.2018.03.001.
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  - Roever, Leonardo, Elmiro Santos Resende, Angélica Lemos Debs Diniz, Nilson Penha-Silva, João Lucas O’Connell, Paulo Fernando Silva Gomes, Hugo Ribeiro Zanetti, et al. “High-density lipoprotein-cholesterol functionality and metabolic syndrome: Protocol for review and meta-analysis.” Medicine (Baltimore) 97, no. 24 (June 2018): e11094. https://doi.org/10.1097/MD.0000000000011094.
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  - Spitzer, Ernest, Eugène McFadden, Pascal Vranckx, Ton de Vries, Ben Ren, Carlos Collet, Yoshinobu Onuma, et al. “Defining Staged Procedures for Percutaneous Coronary Intervention Trials: A Guidance Document.” Jacc Cardiovasc Interv 11, no. 9 (May 14, 2018): 823–32. https://doi.org/10.1016/j.jcin.2018.03.044.
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  - Berwanger, Otavio, Jose C. Nicolau, Antonio C. Carvalho, Lixin Jiang, Shaun G. Goodman, Stephen J. Nicholls, Alexander Parkhomenko, et al. “Ticagrelor vs Clopidogrel After Fibrinolytic Therapy in Patients With ST-Elevation Myocardial Infarction: A Randomized Clinical Trial.” Jama Cardiol 3, no. 5 (May 1, 2018): 391–99. https://doi.org/10.1001/jamacardio.2018.0612.
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  - Lopes, Renato D., Patricia O. Guimarães, Mark Crowther, Elaine Hylek, Gilson S. Feitosa-Filho, Luiz E. Ritt, Nivaldo Filgueiras, and David A. Garcia. “Highlights from the Tenth International Symposium of Thrombosis and Anticoagulation (ISTA X), September 22 and 23, 2017, Salvador, Bahia, Brazil.” J Thromb Thrombolysis 45, no. 4 (May 2018): 578–87. https://doi.org/10.1007/s11239-018-1639-9.
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  - Wang, Alice, Angie Wu, Daniel Wojdyla, Renato D. Lopes, L Kristin Newby, Mark F. Newman, Peter K. Smith, and John H. Alexander. “Dual antiplatelet therapy for perioperative myocardial infarction following CABG surgery.” Am Heart J 199 (May 2018): 150–55. https://doi.org/10.1016/j.ahj.2018.02.006.
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  - Berwanger, Otavio, Eliana Vieira Santucci, Pedro Gabriel Melo de Barros E Silva, Isabella de Andrade Jesuíno, Lucas Petri Damiani, Lilian Mazza Barbosa, Renato Hideo Nakagawa Santos, et al. “Effect of Loading Dose of Atorvastatin Prior to Planned Percutaneous Coronary Intervention on Major Adverse Cardiovascular Events in Acute Coronary Syndrome: The SECURE-PCI Randomized Clinical Trial.” Jama 319, no. 13 (April 3, 2018): 1331–40. https://doi.org/10.1001/jama.2018.2444.
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  - Berwanger, Otavio, Pedro G. M. de Barros E Silva, Frederico Toledo Campo Dall Orto, Pedro Beraldo de Andrade, Igor Ribeiro de Castro Bienert, Carlos Eduardo Bosso, José Mangione, et al. “Rationale and design of the Statins Evaluation in Coronary procedUres and REvascularization: The SECURE-PCI Trial.” Am Heart J 198 (April 2018): 129–34. https://doi.org/10.1016/j.ahj.2017.12.018.
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  - Goto, Shinya, Peter Merrill, Lars Wallentin, Daniel M. Wojdyla, Michael Hanna, Alvaro Avezum, J Donald Easton, et al. “Antithrombotic therapy use and clinical outcomes following thrombo-embolic events in patients with atrial fibrillation: insights from ARISTOTLE.” Eur Heart J Cardiovasc Pharmacother 4, no. 2 (April 1, 2018): 75–81. https://doi.org/10.1093/ehjcvp/pvy002.
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  - Roever, Leonardo, Elmiro Santos Resende, Angélica Lemos Debs Diniz, Nilson Penha-Silva, João Lucas O’Connell, Paulo Fernando Silva Gomes, Hugo Ribeiro Zanetti, et al. “Metabolic syndrome and risk of stroke: Protocol for an update systematic review and meta-analysis.” Medicine (Baltimore) 97, no. 15 (April 2018): e9862. https://doi.org/10.1097/MD.0000000000009862.
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  - Roever, Leonardo, Elmiro Santos Resende, Angélica Lemos Debs Diniz, Nilson Penha-Silva, João Lucas O’Connell, Paulo Fernando Silva Gomes, Hugo Ribeiro Zanetti, et al. “Epicardial adipose tissue and metabolic syndrome: An update protocol for systematic review and meta-analysis.” Medicine (Baltimore) 97, no. 16 (April 2018): e0387. https://doi.org/10.1097/MD.0000000000010387.
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  - Roever, Leonardo, Elmiro Santos Resende, Angélica Lemos Debs Diniz, Nilson Penha-Silva, João Lucas O’Connell, Paulo Fernando Silva Gomes, Hugo Ribeiro Zanetti, et al. “Statins in adult patients with HIV: Protocol for a systematic review and network meta-analysis.” Medicine (Baltimore) 97, no. 15 (April 2018): e0116. https://doi.org/10.1097/MD.0000000000010116.
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  - Roever, Leonardo, Elmiro Santos Resende, Angélica Lemos Debs Diniz, Nilson Penha-Silva, João Lucas O’Connell, Paulo Fernando Silva Gomes, Hugo Ribeiro Zanetti, et al. “Epicardial adipose tissue and carotid artery disease: Protocol for systematic review and meta-analysis.” Medicine (Baltimore) 97, no. 17 (April 2018): e0273. https://doi.org/10.1097/MD.0000000000010273.
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  - Lopes, Renato D., Roberto Rordorf, Gaetano M. De Ferrari, Sergio Leonardi, Laine Thomas, Daniel M. Wojdyla, Peter Ridefelt, et al. “Digoxin and Mortality in Patients With Atrial Fibrillation.” J Am Coll Cardiol 71, no. 10 (March 13, 2018): 1063–74. https://doi.org/10.1016/j.jacc.2017.12.060.
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  - Santos, Eduardo L., Milena M. Gouveia, Ricardo F. Silva, Renata Ávila, Maria A. Aquino, Luca T. Dompieri, and Renato D. Lopes. “Coronary Artery Fistula Causing Acute Myocardial Infarction and Right Ventricle Thrombus.” Cureus 10, no. 3 (March 13, 2018): e2314. https://doi.org/10.7759/cureus.2314.
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  - Santos, Eduardo L., Andre D. Lima, Luca Dompieri, Arthur C. Holanda, Maria A. Aquino, and Renato D. Lopes. “Paradoxical Embolism in a Patient with Aortic Valve Endocarditis: A Case Report.” Cureus 10, no. 3 (March 10, 2018): e2301. https://doi.org/10.7759/cureus.2301.
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  - Chiarito, Mauro, Davide Cao, Francesco Cannata, Cosmo Godino, Corrado Lodigiani, Giuseppe Ferrante, Renato D. Lopes, et al. “Direct Oral Anticoagulants in Addition to Antiplatelet Therapy for Secondary Prevention After Acute Coronary Syndromes: A Systematic Review and Meta-analysis.” Jama Cardiol 3, no. 3 (March 1, 2018): 234–41. https://doi.org/10.1001/jamacardio.2017.5306.
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  - Kopin, David, W Schuyler Jones, Matthew W. Sherwood, Daniel M. Wojdyla, Lars Wallentin, Basil S. Lewis, Freek W. A. Verheugt, et al. “Percutaneous coronary intervention and antiplatelet therapy in patients with atrial fibrillation receiving apixaban or warfarin: Insights from the ARISTOTLE trial.” Am Heart J 197 (March 2018): 133–41. https://doi.org/10.1016/j.ahj.2017.11.005.
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  - Paquet, Maryse, Joshua O. Cerasuolo, Victoria Thorburn, Sebastian Fridman, Rasha Alsubaie, Renato D. Lopes, Lauren E. Cipriano, et al. “Pathophysiology and Risk of Atrial Fibrillation Detected after Ischemic Stroke (PARADISE): A Translational, Integrated, and Transdisciplinary Approach.” J Stroke Cerebrovasc Dis 27, no. 3 (March 2018): 606–19. https://doi.org/10.1016/j.jstrokecerebrovasdis.2017.09.038.
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  - Rao, Meena P., Dragos Vinereanu, Daniel M. Wojdyla, John H. Alexander, Dan Atar, Elaine M. Hylek, Michael Hanna, et al. “Clinical Outcomes and History of Fall in Patients with Atrial Fibrillation Treated with Oral Anticoagulation: Insights From the ARISTOTLE Trial.” Am J Med 131, no. 3 (March 2018): 269-275.e2. https://doi.org/10.1016/j.amjmed.2017.10.036.
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  - Sherwood, Matthew W., Renato D. Lopes, Jie Lena Sun, Danny Liaw, Robert A. Harrington, Lars Wallentin, Daniel T. Laskowitz, et al. “Apixaban following acute coronary syndromes in patients with prior stroke: Insights from the APPRAISE-2 trial.” Am Heart J 197 (March 2018): 1–8. https://doi.org/10.1016/j.ahj.2017.09.020.
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  - Sposato, Luciano A., Sebastian Fridman, Shawn N. Whitehead, and Renato D. Lopes. “Linking stroke-induced heart injury and neurogenic atrial fibrillation: a hypothesis to be proven.” J Electrocardiol, February 20, 2018. https://doi.org/10.1016/j.jelectrocard.2018.02.006.
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  - Hijazi, Ziad, Jonas Oldgren, Johan Lindbäck, John H. Alexander, Stuart J. Connolly, John W. Eikelboom, Michael D. Ezekowitz, et al. “A biomarker-based risk score to predict death in patients with atrial fibrillation: the ABC (age, biomarkers, clinical history) death risk score.” Eur Heart J 39, no. 6 (February 7, 2018): 477–85. https://doi.org/10.1093/eurheartj/ehx584.
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  - Sposato, Luciano A., and Renato D. Lopes. “Oral anticoagulation: a step toward solving the puzzle of dementia related to atrial fibrillation?” Eur Heart J 39, no. 6 (February 7, 2018): 461–63. https://doi.org/10.1093/eurheartj/ehx649.
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  - Vaduganathan, Muthiah, Robert A. Harrington, Gregg W. Stone, Gabriel Steg, C Michael Gibson, Christian W. Hamm, Matthew J. Price, et al. “Short- and long-term mortality following bleeding events in patients undergoing percutaneous coronary intervention: insights from four validated bleeding scales in the CHAMPION trials.” Eurointervention 13, no. 15 (February 2, 2018): e1841–49. https://doi.org/10.4244/EIJ-D-17-00723.
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  - Guimarães, Patrícia O., Sergio Leonardi, Zhen Huang, Lars Wallentin, Frans Van de Werf, Philip E. Aylward, Claes Held, et al. “Clinical features and outcomes of patients with type 2 myocardial infarction: Insights from the Thrombin Receptor Antagonist for Clinical Event Reduction in Acute Coronary Syndrome (TRACER) trial.” Am Heart J 196 (February 2018): 28–35. https://doi.org/10.1016/j.ahj.2017.10.007.
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  - Pol, Tymon, Claes Held, Johan Westerbergh, Johan Lindbäck, John H. Alexander, Marco Alings, Cetin Erol, et al. “Dyslipidemia and Risk of Cardiovascular Events in Patients With Atrial Fibrillation Treated With Oral Anticoagulation Therapy: Insights From the ARISTOTLE (Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation) Trial.” J Am Heart Assoc 7, no. 3 (February 1, 2018). https://doi.org/10.1161/JAHA.117.007444.
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  - Sandhu, Roopinder K., Justin A. Ezekowitz, Ziad Hijazi, Johan Westerbergh, Julia Aulin, John H. Alexander, Christopher B. Granger, et al. “Obesity paradox on outcome in atrial fibrillation maintained even considering the prognostic influence of biomarkers: insights from the ARISTOTLE trial.” Open Heart 5, no. 2 (2018): e000908. https://doi.org/10.1136/openhrt-2018-000908.
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  - Sharma, Abhinav, Jennifer B. Green, Allison Dunning, Yuliya Lokhnygina, Sana M. Al-Khatib, Renato D. Lopes, John B. Buse, et al. “Causes of Death in a Contemporary Cohort of Patients With Type 2 Diabetes and Atherosclerotic Cardiovascular Disease: Insights From the TECOS Trial.” Diabetes Care 40, no. 12 (December 2017): 1763–70. https://doi.org/10.2337/dc17-1091.
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  - Vinereanu, Dragos, Renato D. Lopes, Hillary Mulder, Bernard J. Gersh, Michael Hanna, Pedro G. M. de Barros E Silva, Dan Atar, et al. “Echocardiographic Risk Factors for Stroke and Outcomes in Patients With Atrial Fibrillation Anticoagulated With Apixaban or Warfarin.” Stroke 48, no. 12 (December 2017): 3266–73. https://doi.org/10.1161/STROKEAHA.117.017574.
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  - Williams, Judson B., Eric D. Peterson, Álvaro S. Albrecht, Shuang Li, Sameer A. Hirji, T. Ferguson, Peter K. Smith, and Renato D. Lopes. “Glycemic control in patients undergoing coronary artery bypass graft surgery: Clinical features, predictors, and outcomes.” J Crit Care 42 (December 2017): 328–33. https://doi.org/10.1016/j.jcrc.2017.09.013.
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  - Lopes, Renato D., Patricia O. Guimarães, Elaine Hylek, Gilson S. Feitosa-Filho, Luiz Ritt, Nivaldo Filgueiras, Eduardo Darzé, et al. “Highlights from the Ninth International Symposium of Thrombosis and Anticoagulation (ISTA IX), October 15, 2016, Salvador, Bahia, Brazil.” J Thromb Thrombolysis 44, no. 4 (November 2017): 544–55. https://doi.org/10.1007/s11239-017-1551-8.
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  - Ridker, Paul M., Jean G. MacFadyen, Tom Thuren, Brendan M. Everett, Peter Libby, Robert J. Glynn, and Robert J. CANTOS Trial Group. “Effect of interleukin-1β inhibition with canakinumab on incident lung cancer in patients with atherosclerosis: exploratory results from a randomised, double-blind, placebo-controlled trial.” Lancet 390, no. 10105 (October 21, 2017): 1833–42. https://doi.org/10.1016/S0140-6736(17)32247-X.
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  - Vinereanu, Dragos, Renato D. Lopes, M Cecilia Bahit, Denis Xavier, Jie Jiang, Hussein R. Al-Khalidi, Wensheng He, et al. “A multifaceted intervention to improve treatment with oral anticoagulants in atrial fibrillation (IMPACT-AF): an international, cluster-randomised trial.” Lancet 390, no. 10104 (October 14, 2017): 1737–46. https://doi.org/10.1016/S0140-6736(17)32165-7.
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  - Brüggemann, Roger J., Frank L. van de Veerdonk, and Paul E. Verweij. “Itraconazole or Amphotericin B for Talaromycosis.” N Engl J Med 377, no. 14 (October 5, 2017): 1402–3. https://doi.org/10.1056/NEJMc1709123.
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  - Kittle, Jessie, Renato D. Lopes, Mingyan Huang, Marsha L. Marquess, Matthew D. Wilson, John Ascher, Alok Krishen, et al. “Cardiovascular adverse events in the drug-development program of bupropion for smoking cessation: A systematic retrospective adjudication effort.” Clin Cardiol 40, no. 10 (October 2017): 899–906. https://doi.org/10.1002/clc.22744.
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  - Koshizaka, Masaya, Renato D. Lopes, L Kristin Newby, Robert M. Clare, Phillip J. Schulte, Pierluigi Tricoci, Kenneth W. Mahaffey, et al. “Obesity, Diabetes, and Acute Coronary Syndrome: Differences Between Asians and Whites.” Am J Med 130, no. 10 (October 2017): 1170–76. https://doi.org/10.1016/j.amjmed.2017.03.030.
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  - Vinereanu, Dragos, Hussein R. Al-Khalidi, Meena P. Rao, Wensheng He, Renato D. Lopes, Cecilia M. Bahit, Andrea O. Ciobanu, et al. “Regional differences in presentation and antithrombotic treatment of patients with atrial fibrillation: Baseline characteristics from a clustered randomized trial to IMProve treatment with AntiCoagulanTs in patients with atrial fibrillation (IMPACT-AF).” Am Heart J 192 (October 2017): 38–47. https://doi.org/10.1016/j.ahj.2017.07.004.
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  - Ridker, Paul M., Brendan M. Everett, Tom Thuren, Jean G. MacFadyen, William H. Chang, Christie Ballantyne, Francisco Fonseca, et al. “Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease.” N Engl J Med 377, no. 12 (September 21, 2017): 1119–31. https://doi.org/10.1056/NEJMoa1707914.
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  - Guimarães, Patricia Oliveira, Christopher B. Granger, Amanda Stebbins, Karen Chiswell, Claes Held, Judith S. Hochman, Susan Krug-Gourley, et al. “Sex Differences in Clinical Characteristics, Psychosocial Factors, and Outcomes Among Patients With Stable Coronary Heart Disease: Insights from the STABILITY (Stabilization of Atherosclerotic Plaque by Initiation of Darapladib Therapy) Trial.” J Am Heart Assoc 6, no. 9 (September 14, 2017). https://doi.org/10.1161/JAHA.117.006695.
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  - Hess, Paul L., Hussein R. Al-Khalidi, Daniel J. Friedman, Hillary Mulder, Anna Kucharska-Newton, Wayne R. Rosamond, Renato D. Lopes, et al. “The Metabolic Syndrome and Risk of Sudden Cardiac Death: The Atherosclerosis Risk in Communities Study.” J Am Heart Assoc 6, no. 8 (August 23, 2017). https://doi.org/10.1161/JAHA.117.006103.
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  - Vora, Amit N., Tracy Y. Wang, Shuang Li, Karen Chiswell, Connie Hess, Renato D. Lopes, Sunil V. Rao, and Eric D. Peterson. “Selection of Stent Type in Patients With Atrial Fibrillation Presenting With Acute Myocardial Infarction: An Analysis From the ACTION (Acute Coronary Treatment and Intervention Outcomes Network) Registry-Get With the Guidelines.” J Am Heart Assoc 6, no. 8 (August 21, 2017). https://doi.org/10.1161/JAHA.116.005280.
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  - Gibson, C Michael, Serge Korjian, Gerald Chi, Yazan Daaboul, Purva Jain, Douglas Arbetter, Samuel Z. Goldhaber, et al. “Comparison of Fatal or Irreversible Events With Extended-Duration Betrixaban Versus Standard Dose Enoxaparin in Acutely Ill Medical Patients: An APEX Trial Substudy.” J Am Heart Assoc 6, no. 7 (July 11, 2017). https://doi.org/10.1161/JAHA.117.006015.
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  - Arnold, Donald M., Francois Lauzier, Martin Albert, David Williamson, Na Li, Ryan Zarychanski, Chip Doig, et al. “The association between platelet transfusions and bleeding in critically ill patients with thrombocytopenia.” Res Pract Thromb Haemost 1, no. 1 (July 2017): 103–11. https://doi.org/10.1002/rth2.12004.
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  - Boonyawat, K., F. Caron, A. Li, C. Chai-Adisaksopha, W. Lim, A. Iorio, R. D. Lopes, D. Garcia, and M. A. Crowther. “Association of body weight with efficacy and safety outcomes in phase III randomized controlled trials of direct oral anticoagulants: a systematic review and meta-analysis.” J Thromb Haemost 15, no. 7 (July 2017): 1322–33. https://doi.org/10.1111/jth.13701.
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  - Lopes, Renato D., Marco Alings, Stuart J. Connolly, Heather Beresh, Christopher B. Granger, Juan Benezet Mazuecos, Giuseppe Boriani, et al. “Rationale and design of the Apixaban for the Reduction of Thrombo-Embolism in Patients With Device-Detected Sub-Clinical Atrial Fibrillation (ARTESiA) trial.” Am Heart J 189 (July 2017): 137–45. https://doi.org/10.1016/j.ahj.2017.04.008.
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  - Manning, Michael W., Mary Cooter, Joseph Mathew, John Alexander, Eric Peterson, T Bruce Ferguson, Renato Lopes, and Mihai Podgoreanu. “Angiotensin Receptor Blockade Improves Cardiac Surgical Outcomes in Patients With Metabolic Syndrome.” Ann Thorac Surg 104, no. 1 (July 2017): 98–105. https://doi.org/10.1016/j.athoracsur.2016.10.021.
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  - Hijazi, Ziad, Bertil Lindahl, Jonas Oldgren, Ulrika Andersson, Johan Lindbäck, Christopher B. Granger, John H. Alexander, et al. “Repeated Measurements of Cardiac Biomarkers in Atrial Fibrillation and Validation of the ABC Stroke Score Over Time.” J Am Heart Assoc 6, no. 6 (June 23, 2017). https://doi.org/10.1161/JAHA.116.004851.
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  - Suzumura, Erica Aranha, Rodrigo Antonini Ribeiro, Leticia Kawano-Dourado, Pedro Gabriel de Barros E Silva, Claudia Oliveira, Mabel Fernandes Figueiró, Alexandre Biasi Cavalcanti, Renato D. Lopes, and Otavio Berwanger. “Effects of perioperative statin use on cardiovascular complications in patients submitted to non-cardiac surgery: protocol for a systematic review, meta-analysis, and trial sequential analysis.” Syst Rev 6, no. 1 (June 19, 2017): 116. https://doi.org/10.1186/s13643-017-0500-0.
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  - Guimarães, Patrícia O., Renato D. Lopes, Daniel M. Wojdyla, Azmil H. Abdul-Rahim, Stuart J. Connolly, Greg C. Flaker, Junyuan Wang, et al. “Effect of Apixaban on All-Cause Death in Patients with Atrial Fibrillation: a Meta-Analysis Based on Imputed Placebo Effect.” Cardiovasc Drugs Ther 31, no. 3 (June 2017): 295–301. https://doi.org/10.1007/s10557-017-6728-z.
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  - Lopes, Renato D., Patrícia O. Guimarães, Bradley J. Kolls, Daniel M. Wojdyla, Cheryl D. Bushnell, Michael Hanna, J Donald Easton, et al. “Intracranial hemorrhage in patients with atrial fibrillation receiving anticoagulation therapy.” Blood 129, no. 22 (June 1, 2017): 2980–87. https://doi.org/10.1182/blood-2016-08-731638.
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  - Cowper, Patricia A., Shubin Sheng, Renato D. Lopes, Kevin J. Anstrom, Judith A. Stafford, Linda Davidson-Ray, Sana M. Al-Khatib, et al. “Economic Analysis of Apixaban Therapy for Patients With Atrial Fibrillation From a US Perspective: Results From the ARISTOTLE Randomized Clinical Trial.” Jama Cardiol 2, no. 5 (May 1, 2017): 525–34. https://doi.org/10.1001/jamacardio.2017.0065.
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  - Diepen, Sean van, Peter D. Merrill, Michel Carrier, Jean-Claude Tardif, Mihai Podgoreanu, John H. Alexander, and Renato D. Lopes. “Association between CK-MB Area Under the Curve and Tranexamic Acid Utilization in Patients Undergoing Coronary Artery Bypass Surgery.” J Thromb Thrombolysis 43, no. 4 (May 2017): 446–53. https://doi.org/10.1007/s11239-017-1480-6.
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  - Hess, Connie N., Robert M. Clare, Megan L. Neely, Pierluigi Tricoci, Kenneth W. Mahaffey, Stefan K. James, John H. Alexander, et al. “Differential occurrence, profile, and impact of first recurrent cardiovascular events after an acute coronary syndrome.” Am Heart J 187 (May 2017): 194–203. https://doi.org/10.1016/j.ahj.2017.01.016.
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  - Vora, Amit N., John H. Alexander, and Renato D. Lopes. “Dabigatran Compared With Rivaroxaban vs Warfarin.” Jama Intern Med 177, no. 5 (May 1, 2017): 742–43. https://doi.org/10.1001/jamainternmed.2017.0561.
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  - Guimarães, Patrícia O., Renato D. Lopes, Susanna R. Stevens, André Zimerman, Lisa Wruck, Stefan K. James, Ghazala Haque, Roberto Rocha C. V. Giraldez, John H. Alexander, and Karen P. Alexander. “Reporting Clinical End Points and Safety Events in an Acute Coronary Syndrome Trial: Results With Integrated Collection.” J Am Heart Assoc 6, no. 4 (April 24, 2017). https://doi.org/10.1161/JAHA.117.005490.
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  - Bahit, M Cecilia, Renato D. Lopes, Daniel M. Wojdyla, Claes Held, Michael Hanna, Dragos Vinereanu, Elaine M. Hylek, et al. “Non-major bleeding with apixaban versus warfarin in patients with atrial fibrillation.” Heart 103, no. 8 (April 2017): 623–28. https://doi.org/10.1136/heartjnl-2016-309901.
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  - Ducrocq, Gregory, Phillip J. Schulte, Andrzej Budaj, Jan H. Cornel, Claes Held, Anders Himmelmann, Steen Husted, et al. “Balancing the risk of spontaneous ischemic and major bleeding events in acute coronary syndromes.” Am Heart J 186 (April 2017): 91–99. https://doi.org/10.1016/j.ahj.2017.01.010.
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  - Sharma, Abhinav, Flávio de Souza Brito, Jie-Lena Sun, Laine Thomas, Steven Haffner, Rury R. Holman, and Renato D. Lopes. “Noncardiovascular deaths are more common than cardiovascular deaths in patients with cardiovascular disease or cardiovascular risk factors and impaired glucose tolerance: Insights from the Nateglinide and Valsartan in Impaired Glucose Tolerance Outcomes Research (NAVIGATOR) trial.” Am Heart J 186 (April 2017): 73–82. https://doi.org/10.1016/j.ahj.2016.12.011.
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  - Souza Brito, Flávio de, Rajendra H. Mehta, Renato D. Lopes, Ralf E. Harskamp, B Daniel Lucas, Phillip J. Schulte, Jean-Claude Tardif, and John H. Alexander. “Nonsteroidal Anti-Inflammatory Drugs and Clinical Outcomes in Patients Undergoing Coronary Artery Bypass Surgery.” Am J Med 130, no. 4 (April 2017): 462–68. https://doi.org/10.1016/j.amjmed.2016.10.023.
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  - Hess, Paul L., Jeff S. Healey, Christopher B. Granger, Stuart J. Connolly, Paul D. Ziegler, John H. Alexander, Peter R. Kowey, et al. “The Role of Cardiovascular Implantable Electronic Devices in the Detection and Treatment of Subclinical Atrial Fibrillation: A Review.” Jama Cardiol 2, no. 3 (March 1, 2017): 324–31. https://doi.org/10.1001/jamacardio.2016.5167.
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  - Westenbrink, B Daan, Marco Alings, Christopher B. Granger, John H. Alexander, Renato D. Lopes, Elaine M. Hylek, Laine Thomas, et al. “Anemia is associated with bleeding and mortality, but not stroke, in patients with atrial fibrillation: Insights from the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) trial.” Am Heart J 185 (March 2017): 140–49. https://doi.org/10.1016/j.ahj.2016.12.008.
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  - Armstrong, Paul W., Yinggan Zheng, Cynthia M. Westerhout, Fernado Rosell-Ortiz, Peter Sinnaeve, Yves Lambert, Renato D. Lopes, et al. “Corrigendum to "Reduced dose tenecteplase and outcomes in elderly ST-segment elevation myocardial infarction patients: Insights from the Strategic Reperfusion Early After Myocardial infarction trial" [Am Heart J 169/6 (2015) 890-898].” Am Heart J 184 (February 2017): 157. https://doi.org/10.1016/j.ahj.2017.01.005.
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  - Berwanger, Otavio, Pedro G. M. de Barros E Silva, Roberto Ramos Barbosa, Dalton Bertolim Precoma, Estêvão Lanna Figueiredo, Ludhmila Abrahão Hajjar, Cleber Dario Pinto Kruel, et al. “Atorvastatin for high-risk statin-naïve patients undergoing noncardiac surgery: The Lowering the Risk of Operative Complications Using Atorvastatin Loading Dose (LOAD) randomized trial.” Am Heart J 184 (February 2017): 88–96. https://doi.org/10.1016/j.ahj.2016.11.001.
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  - Tallo, Fernando Sabia, Simone de Campos Vieira Abib, Alexandre Jorgi de Andrade Negri, Paulo Cesar, Renato Delascio Lopes, and Antônio Carlos Lopes. “Evaluation of self-perception of mechanical ventilation knowledge among Brazilian final-year medical students, residents and emergency physicians.” Clinics (Sao Paulo) 72, no. 2 (February 1, 2017): 65–70. https://doi.org/10.6061/clinics/2017(02)01.
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  - Hu, Peter T., Renato D. Lopes, Susanna R. Stevens, Lars Wallentin, Laine Thomas, John H. Alexander, Michael Hanna, et al. “Efficacy and Safety of Apixaban Compared With Warfarin in Patients With Atrial Fibrillation and Peripheral Artery Disease: Insights From the ARISTOTLE Trial.” J Am Heart Assoc 6, no. 1 (January 17, 2017). https://doi.org/10.1161/JAHA.116.004699.
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  - Guimarães, Patrícia O., Daniel M. Wojdyla, John H. Alexander, Laine Thomas, Marco Alings, Greg C. Flaker, Sana M. Al-Khatib, et al. “Anticoagulation therapy and clinical outcomes in patients with recently diagnosed atrial fibrillation: Insights from the ARISTOTLE trial.” Int J Cardiol 227 (January 15, 2017): 443–49. https://doi.org/10.1016/j.ijcard.2016.11.014.
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  - Harumi Higuchi Dos Santos, Marilia, Abhinav Sharma, Jie-Lena Sun, Karen Pieper, John J. V. McMurray, Rury R. Holman, and Renato D. Lopes. “International Variation in Outcomes Among People with Cardiovascular Disease or Cardiovascular Risk Factors and Impaired Glucose Tolerance: Insights from the NAVIGATOR Trial.” J Am Heart Assoc 6, no. 1 (January 13, 2017). https://doi.org/10.1161/JAHA.116.003892.
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  - Dupre, Matthew E., and Renato D. Lopes. “Marital History and Survival After Stroke.” J Am Heart Assoc 5, no. 12 (December 14, 2016). https://doi.org/10.1161/JAHA.116.004647.
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  - Cornel, Jan H., George L. Bakris, Susanna R. Stevens, Michael Alvarsson, Willem A. Bax, Lee-Ming Chuang, Samuel S. Engel, et al. “Effect of Sitagliptin on Kidney Function and Respective Cardiovascular Outcomes in Type 2 Diabetes: Outcomes From TECOS.” Diabetes Care 39, no. 12 (December 2016): 2304–10. https://doi.org/10.2337/dc16-1415.
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  - Katz, Marcelo, Hayden B. Bosworth, Renato D. Lopes, Matthew E. Dupre, Fernando Morita, Carolina Pereira, Fabio G. M. Franco, Rogerio R. Prado, Antonio E. Pesaro, and Mauricio Wajngarten. “A time-series analysis of the relation between unemployment rate and hospital admission for acute myocardial infarction and stroke in Brazil over more than a decade.” Int J Cardiol 224 (December 1, 2016): 33–36. https://doi.org/10.1016/j.ijcard.2016.08.309.
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  - Li, Guowei, Lehana Thabane, Deborah J. Cook, Renato D. Lopes, John C. Marshall, Gordon Guyatt, Anne Holbrook, et al. “Risk factors for and prediction of mortality in critically ill medical-surgical patients receiving heparin thromboprophylaxis.” Ann Intensive Care 6, no. 1 (December 2016): 18. https://doi.org/10.1186/s13613-016-0116-x.
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  - Oldgren, Jonas, Ziad Hijazi, Johan Lindbäck, John H. Alexander, Stuart J. Connolly, John W. Eikelboom, Michael D. Ezekowitz, et al. “Performance and Validation of a Novel Biomarker-Based Stroke Risk Score for Atrial Fibrillation.” Circulation 134, no. 22 (November 29, 2016): 1697–1707. https://doi.org/10.1161/CIRCULATIONAHA.116.022802.
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  - Gomes, Walter J., João Carlos Leal, Domingo M. Braile, Jorge A. Guimarães, Renato D. Lopes, Marcelo A. Lima, and Helena B. Nader. “A Brazilian perspective for the use of bovine heparin in open heart surgery.” Int J Cardiol 223 (November 15, 2016): 611–12. https://doi.org/10.1016/j.ijcard.2016.08.033.
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  - Piccaro de Oliveira, Pedro, Vinicius Gonzales, Renato D. Lopes, Marcia Moura Schmidt, Silvia Garofallo, Rodrigo Pires Dos Santos, Luciana Carrion, Carlos Gottschall, and Alexandre S. Quadros. “Serious infections among unselected patients with ST-elevation myocardial infarction treated with contemporary primary percutaneous coronary intervention.” Am Heart J 181 (November 2016): 52–59. https://doi.org/10.1016/j.ahj.2016.08.005.
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  - Li, Guowei, Deborah J. Cook, Lehana Thabane, Jan O. Friedrich, Tim M. Crozier, John Muscedere, John Granton, et al. “Erratum to: Risk factors for mortality in patients admitted to intensive care units with pneumonia.” Respir Res 17, no. 1 (October 7, 2016): 128. https://doi.org/10.1186/s12931-016-0444-2.
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  - Sandhu, Roopinder K., Justin Ezekowitz, Ulrika Andersson, John H. Alexander, Christopher B. Granger, Sigrun Halvorsen, Michael Hanna, et al. “The 'obesity paradox' in atrial fibrillation: observations from the ARISTOTLE (Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation) trial.” Eur Heart J 37, no. 38 (October 7, 2016): 2869–78. https://doi.org/10.1093/eurheartj/ehw124.
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  - Li, Ang, Renato D. Lopes, and David A. Garcia. “Use of Direct Oral Anticoagulants in Special Populations.” Hematol Oncol Clin North Am 30, no. 5 (October 2016): 1053–71. https://doi.org/10.1016/j.hoc.2016.05.003.
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  - Stroes, Erik, John R. Guyton, Norman Lepor, Fernando Civeira, Daniel Gaudet, Gerald F. Watts, Marie T. Baccara-Dinet, et al. “Efficacy and Safety of Alirocumab 150 mg Every 4 Weeks in Patients With Hypercholesterolemia Not on Statin Therapy: The ODYSSEY CHOICE II Study.” J Am Heart Assoc 5, no. 9 (September 13, 2016). https://doi.org/10.1161/JAHA.116.003421.
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  - Alexander, John H., Ulrika Andersson, Renato D. Lopes, Ziad Hijazi, Stefan H. Hohnloser, Justin A. Ezekowitz, Sigrun Halvorsen, et al. “Apixaban 5 mg Twice Daily and Clinical Outcomes in Patients With Atrial Fibrillation and Advanced Age, Low Body Weight, or High Creatinine: A Secondary Analysis of a Randomized Clinical Trial.” Jama Cardiol 1, no. 6 (September 1, 2016): 673–81. https://doi.org/10.1001/jamacardio.2016.1829.
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  - Jackson, Larry R., Jonathan P. Piccini, Derek D. Cyr, Matthew T. Roe, Megan L. Neely, Felipe Martinez, Thomas F. Lüscher, et al. “Dual Antiplatelet Therapy and Outcomes in Patients With Atrial Fibrillation and Acute Coronary Syndromes Managed Medically Without Revascularization: Insights From the TRILOGY ACS Trial.” Clin Cardiol 39, no. 9 (September 2016): 497–506. https://doi.org/10.1002/clc.22562.
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  - Cohen, Alexander T., Robert A. Harrington, Samuel Z. Goldhaber, Russell D. Hull, Brian L. Wiens, Alex Gold, Adrian F. Hernandez, C Michael Gibson, and C Michael APEX Investigators. “Extended Thromboprophylaxis with Betrixaban in Acutely Ill Medical Patients.” N Engl J Med 375, no. 6 (August 11, 2016): 534–44. https://doi.org/10.1056/NEJMoa1601747.
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  - Hess, Paul L., Renato D. Lopes, and Jeff S. Healey. “Letter by Hess et al Regarding Article, "How to Manage Occult Atrial Fibrillation Detected on Long-Term Monitoring".” Circulation 134, no. 5 (August 2, 2016): e28–29. https://doi.org/10.1161/CIRCULATIONAHA.116.023088.
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  - Armaganijan, Luciana V., Karen P. Alexander, Zhen Huang, Pierluigi Tricoci, Claes Held, Frans Van de Werf, Paul W. Armstrong, et al. “Effect of age on efficacy and safety of vorapaxar in patients with non-ST-segment elevation acute coronary syndrome: Insights from the Thrombin Receptor Antagonist for Clinical Event Reduction in Acute Coronary Syndrome (TRACER) trial.” Am Heart J 178 (August 2016): 176–84. https://doi.org/10.1016/j.ahj.2016.05.012.
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  - Fitzmaurice, David A., Gabriele Accetta, Sylvia Haas, Gloria Kayani, Hector Lucas Luciardi, Frank Misselwitz, Karen Pieper, et al. “Comparison of international normalized ratio audit parameters in patients enrolled in GARFIELD-AF and treated with vitamin K antagonists.” Br J Haematol 174, no. 4 (August 2016): 610–23. https://doi.org/10.1111/bjh.14084.
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  - Jardim, Paulo César Brandão Veiga, Weimar Kunz Sebba Barroso de Souza, Renato Delascio Lopes, Andréa Araújo Brandão, Marcus V Bolívar Malachias, Marco Mota Gomes, Heitor Moreno Júnior, Eduardo Costa Duarte Barbosa, and Rui Manoel Dos Santos Póvoa. “I RBH - First Brazilian Hypertension Registry.” Arq Bras Cardiol 107, no. 2 (August 2016): 93–98. https://doi.org/10.5935/abc.20160120.
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  - Li, Guowei, Deborah J. Cook, Lehana Thabane, Jan O. Friedrich, Tim M. Crozier, John Muscedere, John Granton, et al. “Risk factors for mortality in patients admitted to intensive care units with pneumonia.” Respir Res 17, no. 1 (July 11, 2016): 80. https://doi.org/10.1186/s12931-016-0397-5.
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  - Hijazi, Ziad, Stefan H. Hohnloser, Ulrika Andersson, John H. Alexander, Michael Hanna, Matyas Keltai, Alexander Parkhomenko, et al. “Efficacy and Safety of Apixaban Compared With Warfarin in Patients With Atrial Fibrillation in Relation to Renal Function Over Time: Insights From the ARISTOTLE Randomized Clinical Trial.” Jama Cardiol 1, no. 4 (July 1, 2016): 451–60. https://doi.org/10.1001/jamacardio.2016.1170.
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  - Shimada, Yuichi J., Sameer Bansilal, Stephen D. Wiviott, Richard C. Becker, Robert A. Harrington, Anders Himmelmann, Benjamin Neely, et al. “Impact of glycoprotein IIb/IIIa inhibitors on the efficacy and safety of ticagrelor compared with clopidogrel in patients with acute coronary syndromes: Analysis from the Platelet Inhibition and Patient Outcomes (PLATO) Trial.” Am Heart J 177 (July 2016): 1–8. https://doi.org/10.1016/j.ahj.2016.03.015.
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  - Lopes, Renato D., Karen S. Pieper, Susanna R. Stevens, Scott D. Solomon, John J. V. McMurray, Marc A. Pfeffer, Jeffrey D. Leimberger, and Eric J. Velazquez. “Predicting Outcomes Over Time in Patients With Heart Failure, Left Ventricular Systolic Dysfunction, or Both Following Acute Myocardial Infarction.” J Am Heart Assoc 5, no. 6 (June 27, 2016). https://doi.org/10.1161/JAHA.115.003045.
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  - Jaspers Focks, Jeroen, Marc A. Brouwer, Daniel M. Wojdyla, Laine Thomas, Renato D. Lopes, Jeffrey B. Washam, Fernando Lanas, et al. “Polypharmacy and effects of apixaban versus warfarin in patients with atrial fibrillation: post hoc analysis of the ARISTOTLE trial.” Bmj 353 (June 15, 2016): i2868. https://doi.org/10.1136/bmj.i2868.
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  - Hijazi, Ziad, Jonas Oldgren, Johan Lindbäck, John H. Alexander, Stuart J. Connolly, John W. Eikelboom, Michael D. Ezekowitz, et al. “The novel biomarker-based ABC (age, biomarkers, clinical history)-bleeding risk score for patients with atrial fibrillation: a derivation and validation study.” Lancet 387, no. 10035 (June 4, 2016): 2302–11. https://doi.org/10.1016/S0140-6736(16)00741-8.
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  - Bahit, M Cecilia, Mariano L. Coppola, Patricia M. Riccio, Lauren E. Cipriano, Gregory A. Roth, Renato D. Lopes, Valery L. Feigin, et al. “First-Ever Stroke and Transient Ischemic Attack Incidence and 30-Day Case-Fatality Rates in a Population-Based Study in Argentina.” Stroke 47, no. 6 (June 2016): 1640–42. https://doi.org/10.1161/STROKEAHA.116.013637.
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  - Lopes, Renato D., Angelo Amato Vicenzo de Paola, Adalberto Menezes Lorga Filho, Fernanda Marciano Consolim-Colombo, Jadelson Andrade, Luiz Alberto Piva E Mattos, Sabrina Bernardez-Pereira, Otávio Berwanger, Marcio Jansen de Oliveira Figueiredo, and Marcio Jansen RECALL Steering Committee and Investigators. “Rationale and design of the First Brazilian Cardiovascular Registry of Atrial Fibrillation: The RECALL study.” Am Heart J 176 (June 2016): 10–16. https://doi.org/10.1016/j.ahj.2016.03.001.
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  - Lopes, Renato D., Meena Rao, DaJuanicia N. Simon, Laine Thomas, Jack Ansell, Gregg C. Fonarow, Bernard J. Gersh, et al. “Triple vs Dual Antithrombotic Therapy in Patients with Atrial Fibrillation and Coronary Artery Disease.” Am J Med 129, no. 6 (June 2016): 592-599.e1. https://doi.org/10.1016/j.amjmed.2015.12.026.
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  - Rao, Meena P., Andrea O. Ciobanu, Renato D. Lopes, Kathleen A. Fox, Ying Xian, Sean D. Pokorney, Hussein R. Al-Khalidi, et al. “A clustered randomized trial to IMProve treatment with AntiCoagulanTs in patients with Atrial Fibrillation (IMPACT-AF): design and rationale.” Am Heart J 176 (June 2016): 107–13. https://doi.org/10.1016/j.ahj.2016.03.011.
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  - Harskamp, Ralf E., John H. Alexander, T Bruce Ferguson, Rebecca Hager, Michael J. Mack, Brian Englum, Daniel Wojdyla, et al. “Response to Letters Regarding Article, "Frequency and Predictors of Internal Mammary Artery Graft Failure and Subsequent Clinical Outcomes: Insights From the Project of Ex-Vivo Vein Graft Engineering via Transfection (PREVENT) IV Trial".” Circulation 133, no. 21 (May 24, 2016): e665. https://doi.org/10.1161/CIRCULATIONAHA.116.022510.
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  - Hijazi, Ziad, Johan Lindbäck, John H. Alexander, Michael Hanna, Claes Held, Elaine M. Hylek, Renato D. Lopes, et al. “The ABC (age, biomarkers, clinical history) stroke risk score: a biomarker-based risk score for predicting stroke in atrial fibrillation.” Eur Heart J 37, no. 20 (May 21, 2016): 1582–90. https://doi.org/10.1093/eurheartj/ehw054.
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  - De Caterina, Raffaele, Ulrika Andersson, John H. Alexander, Sana M. Al-Khatib, M Cecilia Bahit, Shinya Goto, Michael Hanna, et al. “History of bleeding and outcomes with apixaban versus warfarin in patients with atrial fibrillation in the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation trial.” Am Heart J 175 (May 2016): 175–83. https://doi.org/10.1016/j.ahj.2016.01.005.
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  - McGuire, Darren K., Frans Van de Werf, Paul W. Armstrong, Eberhard Standl, Joerg Koglin, Jennifer B. Green, M Angelyn Bethel, et al. “Association Between Sitagliptin Use and Heart Failure Hospitalization and Related Outcomes in Type 2 Diabetes Mellitus: Secondary Analysis of a Randomized Clinical Trial.” Jama Cardiol 1, no. 2 (May 1, 2016): 126–35. https://doi.org/10.1001/jamacardio.2016.0103.
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  - Ruff, Christian T., Jack E. Ansell, Richard C. Becker, Emelia J. Benjamin, David J. Deicicchi, N. A. Mark Estes, Michael D. Ezekowitz, et al. “North American Thrombosis Forum, AF Action Initiative Consensus Document.” Am J Med 129, no. 5 Suppl (May 2016): S1–29. https://doi.org/10.1016/j.amjmed.2016.02.001.
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  - Kragholm, Kristian, Sarah A. Goldstein, Qinghong Yang, Renato D. Lopes, Phillip J. Schulte, Gwen M. Bernacki, Harvey D. White, et al. “Trends in Enrollment, Clinical Characteristics, Treatment, and Outcomes According to Age in Non-ST-Segment-Elevation Acute Coronary Syndromes Clinical Trials.” Circulation 133, no. 16 (April 19, 2016): 1560–73. https://doi.org/10.1161/CIRCULATIONAHA.115.017299.
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  - Hijazi, Ziad, Julia Aulin, Ulrika Andersson, John H. Alexander, Bernard Gersh, Christopher B. Granger, Michael Hanna, et al. “Biomarkers of inflammation and risk of cardiovascular events in anticoagulated patients with atrial fibrillation.” Heart 102, no. 7 (April 2016): 508–17. https://doi.org/10.1136/heartjnl-2015-308887.
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  - Prates, Paulo Roberto L., Judson B. Williams, Rajendra H. Mehta, Susanna R. Stevens, Laine Thomas, Peter K. Smith, L Kristin Newby, Renato A. K. Kalil, John H. Alexander, and Renato D. Lopes. “Clopidogrel use After Myocardial Revascularization: Prevalence, Predictors, and One-Year Survival Rate.” Braz J Cardiovasc Surg 31, no. 2 (April 2016): 106–14. https://doi.org/10.5935/1678-9741.20160019.
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  - Streiff, Michael B., Giancarlo Agnelli, Jean M. Connors, Mark Crowther, Sabine Eichinger, Renato D. Lopes, Robert D. McBane, Stephan Moll, and Jack Ansell. “Erratum to: Guidance for the treatment of deep vein thrombosis and pulmonary embolism.” J Thromb Thrombolysis 41, no. 3 (April 2016): 548. https://doi.org/10.1007/s11239-016-1345-4.
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  - Zimerman, André, Renato D. Lopes, Amanda L. Stebbins, Patrícia O. Guimarães, Ghazala Haque, Chiara Melloni, Kathleen Trollinger, et al. “Pooled analysis of adverse event collection from 4 acute coronary syndrome trials.” Am Heart J 174 (April 2016): 60–67. https://doi.org/10.1016/j.ahj.2016.01.003.
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  - Lopes, Renato D., Sergio Leonardi, Benjamin Neely, Megan L. Neely, E Magnus Ohman, Diego Ardissino, Christian W. Hamm, et al. “Spontaneous MI After Non-ST-Segment Elevation Acute Coronary Syndrome Managed Without Revascularization: The TRILOGY ACS Trial.” J Am Coll Cardiol 67, no. 11 (March 22, 2016): 1289–97. https://doi.org/10.1016/j.jacc.2016.01.034.
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  - Rajpurohit, Naveen, Rajiv Gulati, Ryan J. Lennon, Mandeep Singh, Charanjit S. Rihal, Paula J. Santrach, Leslie J. Donato, et al. “Relation of Activated Clotting Times During Percutaneous Coronary Intervention to Outcomes.” Am J Cardiol 117, no. 5 (March 1, 2016): 703–8. https://doi.org/10.1016/j.amjcard.2015.12.003.
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  - Vavalle, John P., Sean van Diepen, Robert M. Clare, Judith S. Hochman, W Douglas Weaver, Rajendra H. Mehta, Karen S. Pieper, et al. “Renal failure in patients with ST-segment elevation acute myocardial infarction treated with primary percutaneous coronary intervention: Predictors, clinical and angiographic features, and outcomes.” Am Heart J 173 (March 2016): 57–66. https://doi.org/10.1016/j.ahj.2015.12.001.
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  - Pesaro, Antonio Eduardo P., Christopher B. Granger, and Renato D. Lopes. “Reduction of ischemic events in Improved Reduction of Outcomes: Vytorin Efficacy International Trial: Intensive cholesterol lowering or ezetimibe antithrombotic effects?” Am Heart J 172 (February 2016): 42–44. https://doi.org/10.1016/j.ahj.2015.11.001.
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  - Sebben, Juliana C., Daniel R. Pinto Ribeiro, Renato D. Lopes, Robert de Winter, Ralf Harskamp, Eduardo Cambruzzi, Marcia Moura Schmidt, Eduarda Schutz Martinelli, Carlos A. Gottschall, and Alexandre S. Quadros. “The role of diabetes mellitus in the composition of coronary thrombi in patients presenting with acute ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention.” Am Heart J 172 (February 2016): 26–33. https://doi.org/10.1016/j.ahj.2015.10.003.
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  - Lincoff, A Michael, Roxana Mehran, Thomas J. Povsic, Steven L. Zelenkofske, Zhen Huang, Paul W. Armstrong, P Gabriel Steg, et al. “Effect of the REG1 anticoagulation system versus bivalirudin on outcomes after percutaneous coronary intervention (REGULATE-PCI): a randomised clinical trial.” Lancet 387, no. 10016 (January 23, 2016): 349–56. https://doi.org/10.1016/S0140-6736(15)00515-2.
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  - Harskamp, Ralf E., John H. Alexander, T Bruce Ferguson, Rebecca Hager, Michael J. Mack, Brian Englum, Daniel Wojdyla, et al. “Frequency and Predictors of Internal Mammary Artery Graft Failure and Subsequent Clinical Outcomes: Insights From the Project of Ex-vivo Vein Graft Engineering via Transfection (PREVENT) IV Trial.” Circulation 133, no. 2 (January 12, 2016): 131–38. https://doi.org/10.1161/CIRCULATIONAHA.115.015549.
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  - Durheim, Michael T., Derek D. Cyr, Renato D. Lopes, Laine E. Thomas, Wayne M. Tsuang, Bernard J. Gersh, Claes Held, et al. “Chronic obstructive pulmonary disease in patients with atrial fibrillation: Insights from the ARISTOTLE trial.” Int J Cardiol 202 (January 1, 2016): 589–94. https://doi.org/10.1016/j.ijcard.2015.09.062.
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  - Pesaro, Antonio Eduardo P., Marcelo Katz, Jason N. Katz, Carmen Sílvia Valente Barbas, Marcia R. Makdisse, Alessandra G. Correa, Marcelo Franken, Carolina Pereira, Carlos V. Serrano, and Renato D. Lopes. “Mechanical Ventilation and Clinical Outcomes in Patients with Acute Myocardial Infarction: A Retrospective Observational Study.” Plos One 11, no. 3 (2016): e0151302. https://doi.org/10.1371/journal.pone.0151302.
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  - Streiff, Michael B., Giancarlo Agnelli, Jean M. Connors, Mark Crowther, Sabine Eichinger, Renato Lopes, Robert D. McBane, Stephan Moll, and Jack Ansell. “Guidance for the treatment of deep vein thrombosis and pulmonary embolism.” J Thromb Thrombolysis 41, no. 1 (January 2016): 32–67. https://doi.org/10.1007/s11239-015-1317-0.
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  - Vinereanu, Dragos, Susanna R. Stevens, John H. Alexander, Sana M. Al-Khatib, Alvaro Avezum, Marıa Cecilia Bahit, Christopher B. Granger, et al. “Clinical outcomes in patients with atrial fibrillation according to sex during anticoagulation with apixaban or warfarin: a secondary analysis of a randomized controlled trial.” Eur Heart J 36, no. 46 (December 7, 2015): 3268–75. https://doi.org/10.1093/eurheartj/ehv447.
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  - Rao, Meena P., Sigrun Halvorsen, Daniel Wojdyla, Laine Thomas, John H. Alexander, Elaine M. Hylek, Michael Hanna, et al. “Blood Pressure Control and Risk of Stroke or Systemic Embolism in Patients With Atrial Fibrillation: Results From the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) Trial.” J Am Heart Assoc 4, no. 12 (December 1, 2015). https://doi.org/10.1161/JAHA.115.002015.
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  - Khan, Razi, Renato D. Lopes, Megan L. Neely, Susanna R. Stevens, Robert A. Harrington, Rafael Diaz, Frank Cools, et al. “Characterising and predicting bleeding in high-risk patients with an acute coronary syndrome.” Heart 101, no. 18 (September 2015): 1475–84. https://doi.org/10.1136/heartjnl-2014-307346.
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  - Hess, Connie N., Stefan James, Renato D. Lopes, Daniel M. Wojdyla, Megan L. Neely, Danny Liaw, Emil Hagstrom, et al. “Apixaban Plus Mono Versus Dual Antiplatelet Therapy in Acute Coronary Syndromes: Insights From the APPRAISE-2 Trial.” J Am Coll Cardiol 66, no. 7 (August 18, 2015): 777–87. https://doi.org/10.1016/j.jacc.2015.06.027.
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  - Harskamp, Ralf E., Thomas A. Vassiliades, Rajendra H. Mehta, Robbert J. de Winter, Renato D. Lopes, Ying Xian, Eric D. Peterson, John D. Puskas, and Michael E. Halkos. “Comparative Effectiveness of Hybrid Coronary Revascularization vs Coronary Artery Bypass Grafting.” J Am Coll Surg 221, no. 2 (August 2015): 326-34.e1. https://doi.org/10.1016/j.jamcollsurg.2015.03.012.
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  - Hess, Connie N., Renato D. Lopes, C Michael Gibson, Rebecca Hager, Daniel M. Wojdyla, Brian R. Englum, Michael J. Mack, Nicholas T. Kouchoukos, Eric D. Peterson, and John H. Alexander. “Response to Letters Regarding Article, "Saphenous Vein Graft Failure After Coronary Artery Bypass Surgery: Insights From PREVENT IV".” Circulation 132, no. 4 (July 28, 2015): e29. https://doi.org/10.1161/CIRCULATIONAHA.115.015362.
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  - Healey, Jeff S., Renato D. Lopes, and Stuart J. Connolly. “The detection and treatment of subclinical atrial fibrillation: evaluating the IMPACT of a comprehensive strategy based on remote arrhythmia monitoring.” Eur Heart J 36, no. 26 (July 7, 2015): 1640–42. https://doi.org/10.1093/eurheartj/ehv159.
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  - Williams, Judson B., Ralf E. Harskamp, Saideep Bose, Jeffrey H. Lawson, John H. Alexander, Peter K. Smith, and Renato D. Lopes. “The Preservation and Handling of Vein Grafts in Current Surgical Practice: Findings of a Survey Among Cardiovascular Surgeons of Top-Ranked US Hospitals.” Jama Surg 150, no. 7 (July 2015): 681–83. https://doi.org/10.1001/jamasurg.2015.0404.
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  - Mahaffey, Kenneth W., Rebecca Hager, Daniel Wojdyla, Harvey D. White, Paul W. Armstrong, John H. Alexander, Pierluigi Tricoci, et al. “Meta-analysis of intracranial hemorrhage in acute coronary syndromes: incidence, predictors, and clinical outcomes.” J Am Heart Assoc 4, no. 6 (June 18, 2015): e001512. https://doi.org/10.1161/JAHA.114.001512.
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  - Albuquerque, Denilson Campos de, João David de Souza Neto, Fernando Bacal, Luiz Eduardo Paim Rohde, Sabrina Bernardez-Pereira, Otavio Berwanger, Dirceu Rodrigues Almeida, and Dirceu Rodrigues Investigadores Estudo BREATHE. “I Brazilian Registry of Heart Failure - Clinical Aspects, Care Quality and Hospitalization Outcomes.” Arq Bras Cardiol 104, no. 6 (June 2015): 433–42. https://doi.org/10.5935/abc.20150031.
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  - Armaganijan, Luciana V., Rodolfo Staico, Dalmo A. R. Moreira, Renato D. Lopes, Paulo T. J. Medeiros, Ricardo Habib, Jônatas Melo Neto, et al. “6-Month Outcomes in Patients With Implantable Cardioverter-Defibrillators Undergoing Renal Sympathetic Denervation for the Treatment of Refractory Ventricular Arrhythmias.” Jacc Cardiovasc Interv 8, no. 7 (June 2015): 984–90. https://doi.org/10.1016/j.jcin.2015.03.012.
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  - Armstrong, Paul W., Yinggan Zheng, Cynthia M. Westerhout, Fernado Rosell-Ortiz, Peter Sinnaeve, Yves Lambert, Renato D. Lopes, et al. “Reduced dose tenecteplase and outcomes in elderly ST-segment elevation myocardial infarction patients: Insights from the STrategic Reperfusion Early After Myocardial infarction trial.” Am Heart J 169, no. 6 (June 2015): 890-898.e1. https://doi.org/10.1016/j.ahj.2015.03.011.
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  - Lopes, Renato D., S Michael Gharacholou, DaJuanicia N. Holmes, Laine Thomas, Tracy Y. Wang, Matthew T. Roe, Eric D. Peterson, and Karen P. Alexander. “Cumulative incidence of death and rehospitalization among the elderly in the first year after NSTEMI.” Am J Med 128, no. 6 (June 2015): 582–90. https://doi.org/10.1016/j.amjmed.2014.12.032.
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  - Held, Claes, Elaine M. Hylek, John H. Alexander, Michael Hanna, Renato D. Lopes, Daniel M. Wojdyla, Laine Thomas, et al. “Clinical outcomes and management associated with major bleeding in patients with atrial fibrillation treated with apixaban or warfarin: insights from the ARISTOTLE trial.” Eur Heart J 36, no. 20 (May 21, 2015): 1264–72. https://doi.org/10.1093/eurheartj/ehu463.
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  - Ciobanu, Andrea O., Sean Bennett, Renato D. Lopes, and Dragos Vinereanu. “Isolated Double Orifice Mitral Valve - a Rare Finding in an Elderly Man.” Arq Bras Cardiol 104, no. 5 (May 2015): e53–54. https://doi.org/10.5935/abc.20150043.
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  - Cornel, Jan H., Renato D. Lopes, Stefan James, Susanna R. Stevens, Megan L. Neely, Danny Liaw, Julie Miller, et al. “Anticoagulant therapy and outcomes in patients with prior or acute heart failure and acute coronary syndromes: Insights from the APixaban for PRevention of Acute ISchemic Events 2 trial.” Am Heart J 169, no. 4 (April 2015): 531–38. https://doi.org/10.1016/j.ahj.2014.12.022.
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  - Ezekowitz, Justin A., Basil S. Lewis, Renato D. Lopes, Daniel M. Wojdyla, John J. V. McMurray, Michael Hanna, Dan Atar, et al. “Clinical outcomes of patients with diabetes and atrial fibrillation treated with apixaban: results from the ARISTOTLE trial.” Eur Heart J Cardiovasc Pharmacother 1, no. 2 (April 2015): 86–94. https://doi.org/10.1093/ehjcvp/pvu024.
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  - Granger, C. B., R. D. Lopes, M. Hanna, J. Ansell, E. M. Hylek, J. H. Alexander, L. Thomas, et al. “Clinical events after transitioning from apixaban versus warfarin to warfarin at the end of the ARISTOTLE trial (vol 169, pg 25, 2014).” American Heart Journal 169, no. 4 (April 2015): 594–594.
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  - Harskamp, Ralf E., Michael E. Halkos, Ying Xian, Molly A. Szerlip, Robert S. Poston, Stephanie L. Mick, Renato D. Lopes, Jan G. Tijssen, Robbert J. de Winter, and Eric D. Peterson. “A nationwide survey on perception, experience, and expectations of hybrid coronary revascularization among top-ranked US hospitals.” Am Heart J 169, no. 4 (April 2015): 557-63.e6. https://doi.org/10.1016/j.ahj.2015.01.003.
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  - Katz, Marcelo, Robert M. Califf, Jie-Lena Sun, John J. V. McMurray, Laine Thomas, and Renato D. Lopes. “Venous thromboembolism and cardiovascular risk: results from the NAVIGATOR trial.” Am J Med 128, no. 3 (March 2015): 297–302. https://doi.org/10.1016/j.amjmed.2014.08.022.
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  - Krishnamoorthy, Arun, Matthew W. Sherwood, Renato D. Lopes, and Richard C. Becker. “The periprocedural management of novel oral anticoagulants in patients with nonvalvular atrial fibrillation: rationale and a summary of the available evidence from phase 3 clinical trials.” Am Heart J 169, no. 3 (March 2015): 315–22. https://doi.org/10.1016/j.ahj.2014.12.008.
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  - Hijazi, Ziad, Agneta Siegbahn, Ulrika Andersson, Bertil Lindahl, Christopher B. Granger, John H. Alexander, Dan Atar, et al. “Comparison of cardiac troponins I and T measured with high-sensitivity methods for evaluation of prognosis in atrial fibrillation: an ARISTOTLE substudy.” Clin Chem 61, no. 2 (February 2015): 368–78. https://doi.org/10.1373/clinchem.2014.226936.
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  - Putera, Martin, Robin Roark, Renato D. Lopes, Krishna Udayakumar, Eric D. Peterson, Robert M. Califf, and Bimal R. Shah. “Translation of acute coronary syndrome therapies: from evidence to routine clinical practice.” Am Heart J 169, no. 2 (February 2015): 266–73. https://doi.org/10.1016/j.ahj.2014.09.015.
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  - Granger, C. B., R. D. Lopes, M. Hanna, J. Ansell, E. M. Hylek, J. H. Alexander, L. Thomas, et al. “Erratum: Clinical events after transitioning from apixaban versus warfarin to warfarin at the end of the ARISTOTLE trial (American Heart Journal (2014) 169:1 (2530) DOI: 10.1016/j.ahj.2014.09.006).” American Heart Journal 169, no. 4 (January 1, 2015): 594. https://doi.org/10.1016/j.ahj.2015.02.005.
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  - Granger, Christopher B., Renato D. Lopes, Michael Hanna, Jack Ansell, Elaine M. Hylek, John H. Alexander, Laine Thomas, et al. “Clinical events after transitioning from apixaban versus warfarin to warfarin at the end of the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) trial.” Am Heart J 169, no. 1 (January 2015): 25–30. https://doi.org/10.1016/j.ahj.2014.09.006.
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  - Guimarães, Patrícia O., Scott Kaatz, and Renato D. Lopes. “Practical and clinical considerations in assessing patients with atrial fibrillation for switching to non-vitamin K antagonist oral anticoagulants in primary care.” Int J Gen Med 8 (2015): 283–91. https://doi.org/10.2147/IJGM.S62760.
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  - Koshizaka, Masaya, Renato D. Lopes, Eric M. Reyes, C Michael Gibson, Phillip J. Schulte, Gail E. Hafley, Adrian F. Hernandez, et al. “Long-term clinical and angiographic outcomes in patients with diabetes undergoing coronary artery bypass graft surgery: results from the Project of Ex-vivo Vein Graft Engineering via Transfection IV trial.” Am Heart J 169, no. 1 (January 2015): 175–84. https://doi.org/10.1016/j.ahj.2014.10.013.
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  - Nutescu, Edith A., Ann K. Wittkowsky, Daniel M. Witt, Scott Kaatz, Jack Ansell, Allison Burnett, David Garcia, et al. “Integrating electronic health records in the delivery of optimized anticoagulation therapy.” Ann Pharmacother 49, no. 1 (January 2015): 125–26. https://doi.org/10.1177/1060028014548570.
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  - Gracieux, Junève, Gillian D. Sanders, Sean D. Pokorney, Renato D. Lopes, Kevin Thomas, and Sana M. Al-Khatib. “Incidence and predictors of appropriate therapies delivered by the implantable cardioverter defibrillator in patients with ischemic cardiomyopathy: a systematic review.” Int J Cardiol 177, no. 3 (December 20, 2014): 990–94. https://doi.org/10.1016/j.ijcard.2014.09.170.
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  - Hohnloser, Stefan H., and Renato D. Lopes. “Atrial fibrillation, valvular heart disease, and use of target-specific oral anticoagulants for stroke prevention.” Eur Heart J 35, no. 47 (December 14, 2014): 3323–25. https://doi.org/10.1093/eurheartj/ehu386.
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  - Garcia, David, John H. Alexander, Lars Wallentin, Daniel M. Wojdyla, Laine Thomas, Michael Hanna, Sana M. Al-Khatib, et al. “Management and clinical outcomes in patients treated with apixaban vs warfarin undergoing procedures.” Blood 124, no. 25 (December 11, 2014): 3692–98. https://doi.org/10.1182/blood-2014-08-595496.
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  - Harskamp, Ralf E., Murad Abdelsalam, Renato D. Lopes, Gouthami Boga, Sameer Hirji, Mrinalini Krishnan, Lukasz Kiljanek, et al. “Cardiac troponin release following hybrid coronary revascularization versus off-pump coronary artery bypass surgery.” Interact Cardiovasc Thorac Surg 19, no. 6 (December 2014): 1008–12. https://doi.org/10.1093/icvts/ivu297.
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  - Wallentin, Lars, Ziad Hijazi, Ulrika Andersson, John H. Alexander, Raffaele De Caterina, Michael Hanna, John D. Horowitz, et al. “Growth differentiation factor 15, a marker of oxidative stress and inflammation, for risk assessment in patients with atrial fibrillation: insights from the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) trial.” Circulation 130, no. 21 (November 18, 2014): 1847–58. https://doi.org/10.1161/CIRCULATIONAHA.114.011204.
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  - Harskamp, Ralf E., Judson B. Williams, Michael E. Halkos, Renato D. Lopes, Jan G. P. Tijssen, T Bruce Ferguson, and Robbert J. de Winter. “Meta-analysis of minimally invasive coronary artery bypass versus drug-eluting stents for isolated left anterior descending coronary artery disease.” J Thorac Cardiovasc Surg 148, no. 5 (November 2014): 1837–42. https://doi.org/10.1016/j.jtcvs.2014.03.028.
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  - Harskamp, Ralf E., Phillip J. Schulte, John H. Alexander, and Renato D. Lopes. “Reply: To PMID 24360877.” Ann Thorac Surg 98, no. 5 (November 2014): 1890. https://doi.org/10.1016/j.athoracsur.2014.08.076.
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  - Hess, Connie N., Renato D. Lopes, C Michael Gibson, Rebecca Hager, Daniel M. Wojdyla, Brian R. Englum, Michael J. Mack, et al. “Saphenous vein graft failure after coronary artery bypass surgery: insights from PREVENT IV.” Circulation 130, no. 17 (October 21, 2014): 1445–51. https://doi.org/10.1161/CIRCULATIONAHA.113.008193.
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  - Barros e Silva, Pedro G. M. de, Robert M. Califf, Jie-Lena Sun, John J. V. McMurray, Rury Holman, Steven Haffner, Laine Thomas, and Renato D. Lopes. “Chronic obstructive pulmonary disease and cardiovascular risk: insights from the NAVIGATOR trial.” Int J Cardiol 176, no. 3 (October 20, 2014): 1126–28. https://doi.org/10.1016/j.ijcard.2014.07.297.
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  - Flaker, Greg, Renato D. Lopes, Elaine Hylek, Daniel M. Wojdyla, Laine Thomas, Sana M. Al-Khatib, Renee M. Sullivan, et al. “Amiodarone, anticoagulation, and clinical events in patients with atrial fibrillation: insights from the ARISTOTLE trial.” J Am Coll Cardiol 64, no. 15 (October 14, 2014): 1541–50. https://doi.org/10.1016/j.jacc.2014.07.967.
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  - Ansell, Jack, Mark Crowther, Allison Burnett, David Garcia, Scott Kaatz, Renato D. Lopes, Edith Nutescu, et al. “Comment on: editorial by Husted et al. "Non-vitamin K antagonist oral anticoagulants (NOACs): no longer new or novel". (Thromb Haemost 2014; 111: 781-782).” Thromb Haemost 112, no. 4 (October 2014): 841. https://doi.org/10.1160/TH14-04-0325.
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  - Bagai, Akshay, Phillip J. Schulte, Christopher B. Granger, Kenneth W. Mahaffey, Robert H. Christenson, Gregory Bell, Renato D. Lopes, et al. “Prognostic implications of creatine kinase-MB measurements in ST-segment elevation myocardial infarction patients treated with primary percutaneous coronary intervention.” Am Heart J 168, no. 4 (October 2014): 503-511.e2. https://doi.org/10.1016/j.ahj.2014.06.008.
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  - Welsh, Robert C., Frans Van de Werf, Cynthia M. Westerhout, Patrick Goldstein, Anthony H. Gershlick, Robert G. Wilcox, Thierry Danays, et al. “Outcomes of a pharmacoinvasive strategy for successful versus failed fibrinolysis and primary percutaneous intervention in acute myocardial infarction (from the STrategic Reperfusion Early After Myocardial Infarction [STREAM] study).” Am J Cardiol 114, no. 6 (September 15, 2014): 811–19. https://doi.org/10.1016/j.amjcard.2014.06.011.
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  - Christersson, C., L. Wallentin, U. Andersson, J. H. Alexander, J. Ansell, R. De Caterina, B. J. Gersh, et al. “D-dimer and risk of thromboembolic and bleeding events in patients with atrial fibrillation--observations from the ARISTOTLE trial.” J Thromb Haemost 12, no. 9 (September 2014): 1401–12. https://doi.org/10.1111/jth.12638.
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  - Goto, Shinya, Jun Zhu, Lisheng Liu, Byung-Hee Oh, Daniel M. Wojdyla, Philip Aylward, M Cecilia Bahit, et al. “Efficacy and safety of apixaban compared with warfarin for stroke prevention in patients with atrial fibrillation from East Asia: a subanalysis of the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) Trial.” Am Heart J 168, no. 3 (September 2014): 303–9. https://doi.org/10.1016/j.ahj.2014.06.005.
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  - Steinberg, Benjamin A., Samuel H. Broderick, Renato D. Lopes, Linda K. Shaw, Kevin L. Thomas, Tracy A. DeWald, James P. Daubert, Eric D. Peterson, Christopher B. Granger, and Jonathan P. Piccini. “Use of antiarrhythmic drug therapy and clinical outcomes in older patients with concomitant atrial fibrillation and coronary artery disease.” Europace 16, no. 9 (September 2014): 1284–90. https://doi.org/10.1093/europace/euu077.
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  - Tallo, Fernando Sabia, Simone de Campos Vieira Abib, André Luciano Baitello, and Renato Delascio Lopes. “An evaluation of the professional, social and demographic profile and quality of life of physicians working at the Prehospital Emergency Medical System (SAMU) in Brazil.” Clinics (Sao Paulo) 69, no. 9 (September 2014): 601–7. https://doi.org/10.6061/clinics/2014(09)05.
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  - Testoni, Daniela, Madoka Hayashi, Michael Cohen-Wolkowiez, Daniel K. Benjamin, Renato D. Lopes, Reese H. Clark, and P Brian Smith. “Late-onset bloodstream infections in hospitalized term infants.” Pediatr Infect Dis J 33, no. 9 (September 2014): 920–23. https://doi.org/10.1097/INF.0000000000000322.
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  - Bernardez-Pereira, Sabrina, Renato D. Lopes, Maria Julia Machline Carrion, Eliana Vieira Santucci, Rafael Marques Soares, Matheus de Oliveira Abreu, Ligia Nasi Laranjeira, et al. “Prevalence, characteristics, and predictors of early termination of cardiovascular clinical trials due to low recruitment: insights from the ClinicalTrials.gov registry.” Am Heart J 168, no. 2 (August 2014): 213-9.e1. https://doi.org/10.1016/j.ahj.2014.04.013.
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  - Diepen, Sean van, J Matthew Brennan, Gail E. Hafley, Eric M. Reyes, Keith B. Allen, T Bruce Ferguson, Eric D. Peterson, et al. “Endoscopic harvesting device type and outcomes in patients undergoing coronary artery bypass surgery.” Ann Surg 260, no. 2 (August 2014): 402–8. https://doi.org/10.1097/SLA.0000000000000377.
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  - Harskamp, Ralf E., John H. Alexander, Phillip J. Schulte, Colleen M. Brophy, Michael J. Mack, Eric D. Peterson, Judson B. Williams, et al. “Vein graft preservation solutions, patency, and outcomes after coronary artery bypass graft surgery: follow-up from the PREVENT IV randomized clinical trial.” Jama Surg 149, no. 8 (August 2014): 798–805. https://doi.org/10.1001/jamasurg.2014.87.
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  - Halvorsen, Sigrun, Dan Atar, Hongqiu Yang, Raffaele De Caterina, Cetin Erol, David Garcia, Christopher B. Granger, et al. “Efficacy and safety of apixaban compared with warfarin according to age for stroke prevention in atrial fibrillation: observations from the ARISTOTLE trial.” Eur Heart J 35, no. 28 (July 21, 2014): 1864–72. https://doi.org/10.1093/eurheartj/ehu046.
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  - Harskamp, Ralf E., John D. Puskas, Jan G. Tijssen, Patrick F. Walker, Henry A. Liberman, Renato D. Lopes, Thomas A. Vassiliades, Eric D. Peterson, and Michael E. Halkos. “Comparison of hybrid coronary revascularization versus coronary artery bypass grafting in patients≥65 years with multivessel coronary artery disease.” Am J Cardiol 114, no. 2 (July 15, 2014): 224–29. https://doi.org/10.1016/j.amjcard.2014.04.028.
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  - Castleberry, Anthony W., Judson B. Williams, Mani A. Daneshmand, Emily Honeycutt, Linda K. Shaw, Zainab Samad, Renato D. Lopes, et al. “Surgical revascularization is associated with maximal survival in patients with ischemic mitral regurgitation: a 20-year experience.” Circulation 129, no. 24 (June 17, 2014): 2547–56. https://doi.org/10.1161/CIRCULATIONAHA.113.005223.
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  - Al-Khatib, Sana M., Nancy M. Allen LaPointe, Ranee Chatterjee, Matthew J. Crowley, Matthew E. Dupre, David F. Kong, Renato D. Lopes, et al. “Rate- and rhythm-control therapies in patients with atrial fibrillation: a systematic review.” Ann Intern Med 160, no. 11 (June 3, 2014): 760–73. https://doi.org/10.7326/M13-1467.
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  - Hylek, Elaine M., Claes Held, John H. Alexander, Renato D. Lopes, Raffaele De Caterina, Daniel M. Wojdyla, Kurt Huber, et al. “Major bleeding in patients with atrial fibrillation receiving apixaban or warfarin: The ARISTOTLE Trial (Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation): Predictors, Characteristics, and Clinical Outcomes.” J Am Coll Cardiol 63, no. 20 (May 27, 2014): 2141–47. https://doi.org/10.1016/j.jacc.2014.02.549.
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  - Staico, Rodolfo, Luciana Armaganijan, Dalmo Moreira, Paulo Medeiros, Jonatas Melo, Renato Lopes, José Ribamar Costa, and Alexandre Abizaid. “Renal sympathetic denervation and ventricular arrhythmias: a case of electrical storm with multiple renal arteries.” Eurointervention 10, no. 1 (May 2014): 166. https://doi.org/10.4244/EIJV10I1A25.
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  - Harskamp, Ralf E., Akshay Bagai, Michael E. Halkos, Sunil V. Rao, William B. Bachinsky, Manesh R. Patel, Robbert J. de Winter, Eric D. Peterson, John H. Alexander, and Renato D. Lopes. “Clinical outcomes after hybrid coronary revascularization versus coronary artery bypass surgery: a meta-analysis of 1,190 patients.” Am Heart J 167, no. 4 (April 2014): 585–92. https://doi.org/10.1016/j.ahj.2014.01.006.
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  - Nelson, James A., John P. Vavalle, Christopher H. May, Aijing Zhang, L Kristin Newby, Linda K. Shaw, Sana M. Al-Khatib, John H. Alexander, Christopher B. Granger, and Renato D. Lopes. “Warfarin use and long-term outcomes in patients with acute myocardial infarction and atrial fibrillation.” J Thromb Thrombolysis 37, no. 3 (April 2014): 331–37. https://doi.org/10.1007/s11239-013-0946-4.
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  - Flaker, Greg, Renato D. Lopes, Sana M. Al-Khatib, Antonio G. Hermosillo, Stefan H. Hohnloser, Brian Tinga, Jun Zhu, et al. “Efficacy and safety of apixaban in patients after cardioversion for atrial fibrillation: insights from the ARISTOTLE Trial (Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation).” J Am Coll Cardiol 63, no. 11 (March 25, 2014): 1082–87. https://doi.org/10.1016/j.jacc.2013.09.062.
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  - Harskamp, Ralf E., John H. Alexander, Phillip J. Schulte, W Schuyler Jones, Judson B. Williams, Michael J. Mack, Eric D. Peterson, et al. “Impact of extracardiac vascular disease on vein graft failure and outcomes after coronary artery bypass surgery.” Ann Thorac Surg 97, no. 3 (March 2014): 824–30. https://doi.org/10.1016/j.athoracsur.2013.09.099.
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  - Lopes, Renato D., and L Kristin Newby. “Response to the Letter to the Editor titled "Atrial fibrillation in patients with acute coronary syndromes".” Int J Cardiol 171, no. 3 (February 15, 2014): e106. https://doi.org/10.1016/j.ijcard.2013.12.006.
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  - Hijazi, Ziad, Agneta Siegbahn, Ulrika Andersson, Christopher B. Granger, John H. Alexander, Dan Atar, Bernard J. Gersh, et al. “High-sensitivity troponin I for risk assessment in patients with atrial fibrillation: insights from the Apixaban for Reduction in Stroke and other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) trial.” Circulation 129, no. 6 (February 11, 2014): 625–34. https://doi.org/10.1161/CIRCULATIONAHA.113.006286.
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  - Diepen, Sean van, Harmony R. Reynolds, Amanda Stebbins, Renato D. Lopes, Vladimír Džavík, Witold Ruzyllo, Alexander Geppert, et al. “Incidence and outcomes associated with early heart failure pharmacotherapy in patients with ongoing cardiogenic shock.” Crit Care Med 42, no. 2 (February 2014): 281–88. https://doi.org/10.1097/CCM.0b013e31829f6242.
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  - Wallentin, Lars, Renato D. Lopes, Michael Hanna, Laine Thomas, Anne Hellkamp, Sunil Nepal, Elaine M. Hylek, et al. “Response to letter regarding article, "Efficacy and safety of apixaban compared with warfarin at different levels of predicted international normalized ratio control for stroke prevention in atrial fibrillation".” Circulation 129, no. 2 (January 14, 2014): e21–22. https://doi.org/10.1161/CIRCULATIONAHA.113.005709.
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  - Alexander, John H., Renato D. Lopes, Laine Thomas, Marco Alings, Dan Atar, Philip Aylward, Shinya Goto, et al. “Apixaban vs. warfarin with concomitant aspirin in patients with atrial fibrillation: insights from the ARISTOTLE trial.” Eur Heart J 35, no. 4 (January 2014): 224–32. https://doi.org/10.1093/eurheartj/eht445.
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  - Harskamp, R. E., J. H. Alexander, P. J. Schulte, W. S. Jones, J. B. Williams, M. J. Mack, E. D. Peterson, et al. “Impact of extracardiac vascular disease on vein graft failure and outcomes after coronary artery bypass surgery.” Annals of Thoracic Surgery 97, no. 3 (2014): 824–30.
  - Welsh, R. C., F. Van de Werf, C. M. Westerhout, P. Goldstein, A. H. Gershlick, R. G. Wilcox, T. Danays, et al. “Outcomes of a pharmacoinvasive strategy for successful versus failed fibrinolysis and primary percutaneous intervention in acute myocardial infarction (from the STrategic Reperfusion Early After Myocardial Infarction [STREAM] study).” The American Journal of Cardiology 114, no. 6 (January 1, 2014): 811–19.
  - Bahit, Maria Cecilia, Renato D. Lopes, Daniel M. Wojdyla, Stefan H. Hohnloser, John H. Alexander, Basil S. Lewis, Philip E. Aylward, et al. “Apixaban in patients with atrial fibrillation and prior coronary artery disease: insights from the ARISTOTLE trial.” Int J Cardiol 170, no. 2 (December 10, 2013): 215–20. https://doi.org/10.1016/j.ijcard.2013.10.062.
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  - Harskamp, Ralf E., Zhe Zheng, John H. Alexander, Judson B. Williams, Ying Xian, Michael E. Halkos, J Matthew Brennan, Robbert J. de Winter, Peter K. Smith, and Renato D. Lopes. “Status quo of hybrid coronary revascularization for multi-vessel coronary artery disease.” Ann Thorac Surg 96, no. 6 (December 2013): 2268–77. https://doi.org/10.1016/j.athoracsur.2013.07.093.
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  - Lauzier, François, Donald M. Arnold, Christian Rabbat, Diane Heels-Ansdell, Ryan Zarychanski, Peter Dodek, Betty Jean Ashley, et al. “Risk factors and impact of major bleeding in critically ill patients receiving heparin thromboprophylaxis.” Intensive Care Med 39, no. 12 (December 2013): 2135–43. https://doi.org/10.1007/s00134-013-3044-3.
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  - Papa, Eduardo D. E., Izo Helber, Manes R. Ehrlichmann, Claudia Maria Rodrigues Alves, Marcia Makdisse, Livia N. Matos, Jairo Lins Borges, Renato D. Lopes, Edson Stefanini, and Antonio Carlos Carvalho. “Ankle-brachial index as a predictor of coronary disease events in elderly patients submitted to coronary angiography.” Clinics (Sao Paulo) 68, no. 12 (December 2013): 1481–87. https://doi.org/10.6061/clinics/2013(12)02.
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  - Armaganijan, Luciana, Dalmo A. Moreira, Roberta R. Nolasco de Araújo, Marcelo A. Puzzi, Fernando P. Munhoz, Murilo J. Carvalho, Lilian N. Gallo, João Italo D. França, and Renato D. Lopes. “The usefulness of T-wave peak to T-wave end interval in identifying malignant arrhythmias in patients with Chagas disease.” Hellenic J Cardiol 54, no. 6 (November 2013): 429–34.
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  - Azevedo, Rudyney E. U., Renato D. Lopes, Maria Eugênia F. Canziani, Iran Gonçalves, Paulo Cesar G. D. Campos, Marcelo L. C. Vieira, Edson Stefanini, and Antonio C. Carvalho. “Mortality after myocardial infarction: the role of renal function and systolic and diastolic functions of the left ventricle.” J Nephrol 26, no. 6 (November 2013): 1089–96. https://doi.org/10.5301/jn.5000294.
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  - Bagai, Akshay, Paul W. Armstrong, Amanda Stebbins, Kenneth W. Mahaffey, Judith S. Hochman, W Douglas Weaver, Manesh R. Patel, Christopher B. Granger, and Renato D. Lopes. “Prognostic implications of left ventricular end-diastolic pressure during primary percutaneous coronary intervention for ST-segment elevation myocardial infarction: Findings from the Assessment of Pexelizumab in Acute Myocardial Infarction study.” Am Heart J 166, no. 5 (November 2013): 913–19. https://doi.org/10.1016/j.ahj.2013.08.006.
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  - Fosbol, Emil L., Tracy Y. Wang, Shuang Li, Jonathan Piccini, Renato D. Lopes, Roger M. Mills, Winslow Klaskala, Laine Thomas, Matthew T. Roe, and Eric D. Peterson. “Warfarin use among older atrial fibrillation patients with non-ST-segment elevation myocardial infarction managed with coronary stenting and dual antiplatelet therapy.” Am Heart J 166, no. 5 (November 2013): 864–70. https://doi.org/10.1016/j.ahj.2013.08.005.
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  - Parashar, Susmita, Danesh Kella, Kimberly J. Reid, John A. Spertus, Fengming Tang, Jonathan Langberg, Viola Vaccarino, Michael C. Kontos, Renato D. Lopes, and Michael S. Lloyd. “New-onset atrial fibrillation after acute myocardial infarction and its relation to admission biomarkers (from the TRIUMPH registry).” Am J Cardiol 112, no. 9 (November 1, 2013): 1390–95. https://doi.org/10.1016/j.amjcard.2013.07.006.
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  - Williams, Judson B., Renato D. Lopes, Gail E. Hafley, T Bruce Ferguson, Michael J. Mack, C Michael Gibson, Robert A. Harrington, et al. “Relationship between postoperative clopidogrel use and subsequent angiographic and clinical outcomes following coronary artery bypass grafting.” J Thromb Thrombolysis 36, no. 4 (November 2013): 384–93. https://doi.org/10.1007/s11239-013-0904-1.
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  - Ritt, Luiz Eduardo, Antonio Carlos Carvalho, Gilson Soares Feitosa, Joel A. Pinho-Filho, Marcus Vinicius Santos Andrade, Gilson Soares Feitosa-Filho, L Kristin Newby, and Renato D. Lopes. “Cardiopulmonary exercise and 6-min walk tests as predictors of quality of life and long-term mortality among patients with heart failure due to Chagas disease.” Int J Cardiol 168, no. 4 (October 9, 2013): 4584–85. https://doi.org/10.1016/j.ijcard.2013.06.064.
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  - Schmidt, Márcia M., Renato D. Lopes, L Kristin Newby, Mauro R. Moura, Luciele Stochero, Carlos M. Gottschall, and Alexandre S. Quadros. “Anger control and cardiovascular outcomes.” Int J Cardiol 168, no. 4 (October 9, 2013): 4338–39. https://doi.org/10.1016/j.ijcard.2013.05.083.
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  - Diepen, Sean van, L Kristin Newby, Renato D. Lopes, Amanda Stebbins, Vic Hasselblad, Stefan James, Matthew T. Roe, et al. “Prognostic relevance of baseline pro- and anti-inflammatory markers in STEMI: an APEX AMI substudy.” Int J Cardiol 168, no. 3 (October 3, 2013): 2127–33. https://doi.org/10.1016/j.ijcard.2013.01.004.
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  - Lopes, Renato D., Jennifer A. White, Dan Atar, Matyas Keltai, Neal S. Kleiman, Harvey D. White, Petr Widimsky, et al. “Incidence, treatment, and outcomes of atrial fibrillation complicating non-ST-segment elevation acute coronary syndromes.” Int J Cardiol 168, no. 3 (October 3, 2013): 2510–17. https://doi.org/10.1016/j.ijcard.2013.03.037.
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  - Giraldez, Roberto Rocha, Renato D. Lopes, and L Kristin Newby. “Responding to the letter to the editor by Saver.” Am Heart J 166, no. 4 (October 2013): e39. https://doi.org/10.1016/j.ahj.2013.08.022.
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  - Sposato, Luciano A., Mariano L. Coppola, Juan Altamirano, Brenda Borrego Guerrero, Jorge Casanova, Maximiliano De Martino, Alejandro Díaz, et al. “Program for the epidemiological evaluation of stroke in Tandil, Argentina (PREVISTA) study: rationale and design.” Int J Stroke 8, no. 7 (October 2013): 591–97. https://doi.org/10.1111/ijs.12171.
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  - Lopes, Renato D., Jennifer A. White, Pierluigi Tricoci, Harvey D. White, Paul W. Armstrong, Eugene Braunwald, Robert P. Giugliano, et al. “Age, treatment, and outcomes in high-risk non-ST-segment elevation acute coronary syndrome patients: insights from the EARLY ACS trial.” Int J Cardiol 167, no. 6 (September 10, 2013): 2580–87. https://doi.org/10.1016/j.ijcard.2012.06.053.
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  - Garcia, David A., Lars Wallentin, Renato D. Lopes, Laine Thomas, John H. Alexander, Elaine M. Hylek, Jack Ansell, et al. “Apixaban versus warfarin in patients with atrial fibrillation according to prior warfarin use: results from the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation trial.” Am Heart J 166, no. 3 (September 2013): 549–58. https://doi.org/10.1016/j.ahj.2013.05.016.
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  - Hess, Connie N., Sana M. Al-Khatib, Christopher B. Granger, and Renato Lopes. “A review of apixaban for stroke prevention in atrial fibrillation: insights from ARISTOTLE.” Expert Rev Cardiovasc Ther 11, no. 9 (September 2013): 1105–14. https://doi.org/10.1586/14779072.2013.824181.
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  - Lorga Filho, A. M., A. D. Azmus, A. M. Soeiro, A. S. Quadros, A. Avezum, A. C. Marques, A. Franci, et al. “[Brazilian guidelines on platelet antiaggregants and anticoagulants in cardiology].” Arq Bras Cardiol 101, no. 3 Suppl 3 (September 2013): 1–95. https://doi.org/10.5935/abc.2013S009.
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  - Steinberg, Benjamin A., Sunghee Kim, Jonathan P. Piccini, Gregg C. Fonarow, Renato D. Lopes, Laine Thomas, Michael D. Ezekowitz, et al. “Use and associated risks of concomitant aspirin therapy with oral anticoagulation in patients with atrial fibrillation: insights from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) Registry.” Circulation 128, no. 7 (August 13, 2013): 721–28. https://doi.org/10.1161/CIRCULATIONAHA.113.002927.
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  - Al-Khatib, Sana M., Laine Thomas, Lars Wallentin, Renato D. Lopes, Bernard Gersh, David Garcia, Justin Ezekowitz, et al. “Outcomes of apixaban vs. warfarin by type and duration of atrial fibrillation: results from the ARISTOTLE trial.” Eur Heart J 34, no. 31 (August 2013): 2464–71. https://doi.org/10.1093/eurheartj/eht135.
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  - Gonzalez, M. M., S. Timerman, R. Gianotto-Oliveira, T. F. Polastri, M. F. Canesin, A. Schimidt, A. W. Siqueira, et al. “[First guidelines of the Brazilian Society of Cardiology on Cardiopulmonary Resuscitation and Cardiovascular Emergency Care].” Arq Bras Cardiol 101, no. 2 Suppl 3 (August 2013): 1–221. https://doi.org/10.5935/abc.2013S006.
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  - Koshizaka, M., R. D. Lopes, L. K. Newby, P. J. Schulte, R. M. Clare, P. Tricoci, K. W. Mahaffey, H. Ogawa, R. A. Harrington, and J. H. Alexander. “Relationship between diabetes, race, obesity and outcomes in patients with acute coronary syndrome: a pool analysis from randomized trials.” European Heart Journal 34 (August 1, 2013): 787–787.
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  - Lopes, Renato D., Sheila Dickerson, Gail Hafley, Shana Burns, Sandra Tourt-Uhlig, Jennifer White, L Kristin Newby, et al. “Methodology of a reevaluation of cardiovascular outcomes in the RECORD trial: study design and conduct.” Am Heart J 166, no. 2 (August 2013): 208-216.e28. https://doi.org/10.1016/j.ahj.2013.05.005.
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  - Mahaffey, Kenneth W., Gail Hafley, Sheila Dickerson, Shana Burns, Sandra Tourt-Uhlig, Jennifer White, L Kristin Newby, et al. “Results of a reevaluation of cardiovascular outcomes in the RECORD trial.” Am Heart J 166, no. 2 (August 2013): 240-249.e1. https://doi.org/10.1016/j.ahj.2013.05.004.
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  - Cullen, Michael W., Sunghee Kim, Jonathan P. Piccini, Jack E. Ansell, Greg C. Fonarow, Elaine M. Hylek, Daniel E. Singer, et al. “Risks and benefits of anticoagulation in atrial fibrillation: insights from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) registry.” Circ Cardiovasc Qual Outcomes 6, no. 4 (July 2013): 461–69. https://doi.org/10.1161/CIRCOUTCOMES.113.000127.
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  - Lopes, Renato D., Richard C. Becker, L Kristin Newby, Eric D. Peterson, Elaine M. Hylek, Robert Giugliano, Christopher B. Granger, et al. “Highlights from the fifth international symposium of thrombosis and anticoagulation (ISTA V), October 18-19, 2012, Belo Horizonte, Minas Gerais, Brazil.” J Thromb Thrombolysis 36, no. 1 (July 2013): 115–30. https://doi.org/10.1007/s11239-013-0906-z.
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  - Souza Brito, Flavio de, Renato D. Lopes, and John H. Alexander. “The safety and efficacy of apixaban : where do we stand in 2013?” Expert Opin Drug Saf 12, no. 4 (July 2013): 559–67. https://doi.org/10.1517/14740338.2013.799663.
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  - Hijazi, Ziad, Lars Wallentin, Agneta Siegbahn, Ulrika Andersson, Christina Christersson, Justin Ezekowitz, Bernard J. Gersh, et al. “N-terminal pro-B-type natriuretic peptide for risk assessment in patients with atrial fibrillation: insights from the ARISTOTLE Trial (Apixaban for the Prevention of Stroke in Subjects With Atrial Fibrillation).” J Am Coll Cardiol 61, no. 22 (June 4, 2013): 2274–84. https://doi.org/10.1016/j.jacc.2012.11.082.
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  - Wallentin, Lars, Renato D. Lopes, Michael Hanna, Laine Thomas, Anne Hellkamp, Sunil Nepal, Elaine M. Hylek, et al. “Efficacy and safety of apixaban compared with warfarin at different levels of predicted international normalized ratio control for stroke prevention in atrial fibrillation.” Circulation 127, no. 22 (June 4, 2013): 2166–76. https://doi.org/10.1161/CIRCULATIONAHA.112.142158.
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  - Bahit, Maria Cecilia, Renato D. Lopes, Robert M. Clare, L Kristin Newby, Karen S. Pieper, Frans Van de Werf, Paul W. Armstrong, et al. “Heart failure complicating non-ST-segment elevation acute coronary syndrome: timing, predictors, and clinical outcomes.” Jacc Heart Fail 1, no. 3 (June 2013): 223–29. https://doi.org/10.1016/j.jchf.2013.02.007.
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  - Giraldez, Roberto R., Robert M. Clare, Renato D. Lopes, Anthony J. Dalby, Dorairaj Prabhakaran, Gerard X. Brogan, Robert P. Giugliano, et al. “Prevalence and clinical outcomes of undiagnosed diabetes mellitus and prediabetes among patients with high-risk non-ST-segment elevation acute coronary syndrome.” Am Heart J 165, no. 6 (June 2013): 918-925.e2. https://doi.org/10.1016/j.ahj.2013.01.005.
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  - Leonardi, Sergio, Amanda Stebbins, Renato D. Lopes, Yuliya Lokhnygina, Meredith Todd, Deepak L. Bhatt, Gregg W. Stone, et al. “Quantification of the effect of clopidogrel on enzymatic infarct size related to a percutaneous coronary intervention in patients with acute coronary syndromes: insights from the CHAMPION percutaneous coronary intervention trial.” Coron Artery Dis 24, no. 4 (June 2013): 321–27. https://doi.org/10.1097/MCA.0b013e32835f2fbd.
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  - Nicolau, José C., Ramon Corbalan, Rafael Diaz, Cecilia Bahit, Paul W. Armstrong, Christopher B. Granger, and Renato D. Lopes. “Cardiovascular clinical research in South America.” Am Heart J 165, no. 6 (June 2013): 848–53. https://doi.org/10.1016/j.ahj.2013.02.004.
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  - Lopes, Renato D., Yuliya Lokhnygina, Victor Hasselblad, Kristin L. Newby, Eric Yow, Christopher B. Granger, Paul W. Armstrong, et al. “Methods of creatine kinase-MB analysis to predict mortality in patients with myocardial infarction treated with reperfusion therapy.” Trials 14 (May 2, 2013): 123. https://doi.org/10.1186/1745-6215-14-123.
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  - Harskamp, Ralf E., Judson B. Williams, Ronald C. Hill, Robbert J. de Winter, John H. Alexander, and Renato D. Lopes. “Saphenous vein graft failure and clinical outcomes: toward a surrogate end point in patients following coronary artery bypass surgery?” Am Heart J 165, no. 5 (May 2013): 639–43. https://doi.org/10.1016/j.ahj.2013.01.019.
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  - Harskamp, Ralf E., Renato D. Lopes, Clinton E. Baisden, Robbert J. de Winter, and John H. Alexander. “Saphenous vein graft failure after coronary artery bypass surgery: pathophysiology, management, and future directions.” Ann Surg 257, no. 5 (May 2013): 824–33. https://doi.org/10.1097/SLA.0b013e318288c38d.
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  - Lopes, Renato D., Christopher B. Granger, and Karen P. Alexander. “The reply.” Am J Med 126, no. 5 (May 2013): e21. https://doi.org/10.1016/j.amjmed.2013.01.002.
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  - McMurray, John J. V., Justin A. Ezekowitz, Basil S. Lewis, Bernard J. Gersh, Sean van Diepen, John Amerena, Jozef Bartunek, et al. “Left ventricular systolic dysfunction, heart failure, and the risk of stroke and systemic embolism in patients with atrial fibrillation: insights from the ARISTOTLE trial.” Circ Heart Fail 6, no. 3 (May 2013): 451–60. https://doi.org/10.1161/CIRCHEARTFAILURE.112.000143.
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  - Rose, Jason J., L Kristin Newby, Samuel Broderick, Karen Chiswell, Frans Van de Werf, Paul W. Armstrong, Kenneth W. Mahaffey, et al. “Left bundle branch block in non-ST-segment elevation acute coronary syndromes. Incidence, angiographic characteristics, and clinical outcomes.” J Am Coll Cardiol 61, no. 13 (April 2, 2013): 1461–63. https://doi.org/10.1016/j.jacc.2012.12.032.
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  - Guptill, Jeffrey T., Rajendra H. Mehta, Paul W. Armstrong, John Horton, Daniel Laskowitz, Stefan James, Christopher B. Granger, and Renato D. Lopes. “Stroke after primary percutaneous coronary intervention in patients with ST-segment elevation myocardial infarction: timing, characteristics, and clinical outcomes.” Circ Cardiovasc Interv 6, no. 2 (April 2013): 176–83. https://doi.org/10.1161/CIRCINTERVENTIONS.112.000159.
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  - Berwanger, Otávio, Luiz Alberto Piva e Mattos, José Fernando Vilela Martin, Renato Delascio Lopes, Estevão Lanna Figueiredo, Daniel Magnoni, Dalton Bertolim Precoma, Carlos Alberto Machado, Jorge Ilha Guimarães, and Jadelson Pinheiro de Andrade. “Evidence-based therapy prescription in high-cardiovascular risk patients: the REACT study.” Arq Bras Cardiol 100, no. 3 (March 2013): 212–20. https://doi.org/10.5935/abc.20130062.
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  - Truffa, Adriano A., Renato D. Lopes, and L Kristin Newby. “Alternatives to warfarin for stroke prevention in patients with nonvalvular atrial fibrillation: a look back at the state of the field in 2012.” Postgrad Med 125, no. 2 (March 2013): 146–57. https://doi.org/10.3810/pgm.2013.03.2648.
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  - Lopes, R. D., S. M. Al-Khatib, and L. Wallentin. “Efficacy and safety of apixaban compared with warfarin according to patient risk of stroke and of bleeding in atrial fibrillation: a secondary analysis of a randomised controlled trial (vol 380, pg 1749, 2012).” Lancet 381, no. 9862 (January 19, 2013): 204–204.
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  - Harskamp, Ralf E., Marcel A. Beijk, Peter Damman, Jan G. Tijssen, Renato D. Lopes, and Robbert J. de Winter. “Prehospitalization antiplatelet therapy and outcomes after saphenous vein graft intervention.” Am J Cardiol 111, no. 2 (January 15, 2013): 153–58. https://doi.org/10.1016/j.amjcard.2012.09.010.
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  - Lauzier, F., D. M. Arnold, C. Rabbat, D. Heels-Ansdell, R. Zarychanski, P. Dodek, B. J. Ashley, et al. “Risk factors and impact of major bleeding in critically ill patients receiving heparin thromboprophylaxis.” Intensive Care Medicine, 2013, 1–9.
  - Lopes, R. D., S. M. Al-Khatib, and L. Wallentin. “Erratum: Efficacy and safety of apixaban compared with warfarin according to patient risk of stroke and of bleeding in atrial fi brillation: A secondary analysis of a randomised controlled trial (The Lancet (2012) 380 (1749-58)).” The Lancet 381, no. 9862 (January 1, 2013): 204.
  - Staico, R., L. Armaganijan, C. Dietrich, A. Abizaid, D. Moreira, R. Lopes, J. Almeida, and M. Franco. “Renal sympathetic ablation using an irrigated-tip catheter: An attractive option?” Revista Brasileira De Cardiologia Invasiva 21, no. 1 (January 1, 2013). https://doi.org/10.1016/s0104-1843(13)50004-x.
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  - Eapen, Z. J., R. D. Lopes, S. M. Al-Khatib, Y. Wang, H. Bao, J. Curtis, P. A. Heidenreich, A. F. Hernandez, D. P. Eric, and S. C. Hammill. “Erratum: Are racial/ethnic gaps in the use of cardiac resynchronization therapy narrowing? An analysis of 107,096 patients from the national cardiovascular data registrys ICD registry (Journal of the American College of Cardiology (2012) 60(1577-80)).” Journal of the American College of Cardiology 60, no. 24 (December 18, 2012): 2605. https://doi.org/10.1016/j.jacc.2012.10.004.
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  - Leonardi, Sergio, Laine Thomas, Megan L. Neely, Pierluigi Tricoci, Renato D. Lopes, Harvey D. White, Paul W. Armstrong, et al. “Comparison of the prognosis of spontaneous and percutaneous coronary intervention-related myocardial infarction.” J Am Coll Cardiol 60, no. 22 (December 4, 2012): 2296–2304. https://doi.org/10.1016/j.jacc.2012.09.005.
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  - Cecilia Bahit, Maria, Renato D. Lopes, Stephan H. Hohnloser, Daniel Wojdyla, John H. Alexander, Basil S. Lewis, Philip Aylward, et al. “Apixaban in Patients with Atrial Fibrillation and Prior Coronary Artery Disease: Insights from the ARISTOTLE Trial.” Circulation 126, no. 21 (November 20, 2012).
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  - Hylek, Elaine M., Claes Held, John H. Alexander, Renato D. Lopes, Raffaele DeCaterina, Kurt Huber, Petr Jansky, et al. “Reduction in Bleeding with Apixaban versus Warfarin is Consistent Across Subgroups and Locations: Insights from the ARISTOTLE Trial.” Circulation 126, no. 21 (November 20, 2012).
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  - Lopes, Renato D., Sana M. Al-Khatib, Lars Wallentin, Hongqiu Yang, Jack Ansell, M Cecilia Bahit, Raffaele De Caterina, et al. “Efficacy and safety of apixaban compared with warfarin according to patient risk of stroke and of bleeding in atrial fibrillation: a secondary analysis of a randomised controlled trial.” Lancet 380, no. 9855 (November 17, 2012): 1749–58. https://doi.org/10.1016/S0140-6736(12)60986-6.
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  - Hess, Connie N., Richard C. Becker, John H. Alexander, and Renato D. Lopes. “Antithrombotic therapy in heparin-induced thrombocytopenia: guidelines translated for the clinician.” J Thromb Thrombolysis 34, no. 4 (November 2012): 552–61. https://doi.org/10.1007/s11239-012-0785-8.
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  - Hohnloser, Stefan H., Ziad Hijazi, Laine Thomas, John H. Alexander, John Amerena, Michael Hanna, Matyas Keltai, et al. “Efficacy of apixaban when compared with warfarin in relation to renal function in patients with atrial fibrillation: insights from the ARISTOTLE trial.” Eur Heart J 33, no. 22 (November 2012): 2821–30. https://doi.org/10.1093/eurheartj/ehs274.
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  - Lopes, Renato D., Li Li, Christopher B. Granger, Tracy Y. Wang, JoAnne M. Foody, Marjorie Funk, Eric D. Peterson, and Karen P. Alexander. “Atrial fibrillation and acute myocardial infarction: antithrombotic therapy and outcomes.” Am J Med 125, no. 9 (September 2012): 897–905. https://doi.org/10.1016/j.amjmed.2012.04.006.
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  - Pesaro, Antonio Eduardo P., Carlos V. Serrano, Marcelo Katz, Alexandre H. Campos, Renato D. Lopes, Luciana C. Marti, Herlon S. Martins, Rodrigo S. Sunahara, Raul C. Maranhão, and José C. Nicolau. “Inflammation and circulating endothelial progenitor cells in patients with coronary artery disease and residual platelet reactivity.” Clinics (Sao Paulo) 67, no. 9 (September 2012): 1117–21. https://doi.org/10.6061/clinics/2012(09)21.
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  - Rao, Sunil V., David Dai, Sumeet Subherwal, William S. Weintraub, Ralph S. Brindis, John C. Messenger, Renato D. Lopes, and Eric D. Peterson. “Association between periprocedural bleeding and long-term outcomes following percutaneous coronary intervention in older patients.” Jacc Cardiovasc Interv 5, no. 9 (September 2012): 958–65. https://doi.org/10.1016/j.jcin.2012.05.010.
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  - Lopes, Renato D., Sumeet Subherwal, Dajuanicia N. Holmes, Laine Thomas, Tracy Y. Wang, Sunil V. Rao, Erik Magnus Ohman, Matthew T. Roe, Eric D. Peterson, and Karen P. Alexander. “The association of in-hospital major bleeding with short-, intermediate-, and long-term mortality among older patients with non-ST-segment elevation myocardial infarction.” Eur Heart J 33, no. 16 (August 2012): 2044–53. https://doi.org/10.1093/eurheartj/ehs012.
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  - Williams, Judson B., Eric D. Peterson, J Matthew Brennan, Art Sedrakyan, Dale Tavris, John H. Alexander, Renato D. Lopes, et al. “Association between endoscopic vs open vein-graft harvesting and mortality, wound complications, and cardiovascular events in patients undergoing CABG surgery.” Jama 308, no. 5 (August 1, 2012): 475–84. https://doi.org/10.1001/jama.2012.8363.
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  - Diepen, Sean van, Matthew T. Roe, Renato D. Lopes, Amanda Stebbins, Stefan James, L Kristin Newby, David J. Moliterno, et al. “Baseline NT-proBNP and biomarkers of inflammation and necrosis in patients with ST-segment elevation myocardial infarction: insights from the APEX-AMI trial.” J Thromb Thrombolysis 34, no. 1 (July 2012): 106–13. https://doi.org/10.1007/s11239-012-0691-0.
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  - Diepen, Sean van, Petr Widimsky, Renato D. Lopes, Kyle R. White, W Douglas Weaver, Frans Van de Werf, Diego Ardissino, Arnoud W. J. van’t Hof, Paul W. Armstrong, and Christopher B. Granger. “Transfer times and outcomes in patients with ST-segment-elevation myocardial infarction undergoing interhospital transfer for primary percutaneous coronary intervention: APEX-AMI insights.” Circ Cardiovasc Qual Outcomes 5, no. 4 (July 1, 2012): 437–44. https://doi.org/10.1161/CIRCOUTCOMES.112.965160.
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  - Lopes, Renato D., Richard C. Becker, L Kristin Newby, Eric D. Peterson, Elaine M. Hylek, Christopher B. Granger, Mark Crowther, et al. “Highlights from the IV International Symposium of Thrombosis and Anticoagulation (ISTA), October 20-21, 2011, Salvador, Bahia, Brazil.” J Thromb Thrombolysis 34, no. 1 (July 2012): 143–63. https://doi.org/10.1007/s11239-012-0700-3.
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  - Truffa, Adriano A. M., Christopher B. Granger, Kyle R. White, L Kristin Newby, Rajendra H. Mehta, Judith S. Hochman, Manesh R. Patel, et al. “Serious infection after acute myocardial infarction: incidence, clinical features, and outcomes.” Jacc Cardiovasc Interv 5, no. 7 (July 2012): 769–76. https://doi.org/10.1016/j.jcin.2012.03.018.
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  - James, Stefan K., Robert F. Storey, Nardev S. Khurmi, Steen Husted, Matyas Keltai, Kenneth W. Mahaffey, Juan Maya, et al. “Ticagrelor versus clopidogrel in patients with acute coronary syndromes and a history of stroke or transient ischemic attack.” Circulation 125, no. 23 (June 12, 2012): 2914–21. https://doi.org/10.1161/CIRCULATIONAHA.111.082727.
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  - Easton, J Donald, Renato D. Lopes, M Cecilia Bahit, Daniel M. Wojdyla, Christopher B. Granger, Lars Wallentin, Marco Alings, et al. “Apixaban compared with warfarin in patients with atrial fibrillation and previous stroke or transient ischaemic attack: a subgroup analysis of the ARISTOTLE trial.” Lancet Neurol 11, no. 6 (June 2012): 503–11. https://doi.org/10.1016/S1474-4422(12)70092-3.
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  - Ritt, Luiz E., Antonio Carlos Carvalho, Gilson S. Feitosa, Joel A. Pinho-Filho, Cristiano R. B. Macedo, Fabio Vilas-Boas, Marcus V. S. Andrade, et al. “Heart failure survival score in patients with Chagas disease: correlation with functional variables.” Rev Esp Cardiol (Engl Ed) 65, no. 6 (June 2012): 538–43. https://doi.org/10.1016/j.recesp.2011.12.019.
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  - Berwanger, Otávio, Hélio P. Guimarães, Ligia N. Laranjeira, Alexandre B. Cavalcanti, Alessandra A. Kodama, Ana Denise Zazula, Eliana V. Santucci, et al. “Effect of a multifaceted intervention on use of evidence-based therapies in patients with acute coronary syndromes in Brazil: the BRIDGE-ACS randomized trial.” Jama 307, no. 19 (May 16, 2012): 2041–49. https://doi.org/10.1001/jama.2012.413.
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  - Katz, Marcelo, Flavio Tarasoutchi, Antonio Eduardo Pereira Pesaro, Renato D. Lopes, Guilherme Sobreira Spina, Marcelo Luiz Campos Vieira, and Max Grinberg. “Natriuretic peptides and long-term mortality in patients with severe aortic stenosis.” J Heart Valve Dis 21, no. 3 (May 2012): 331–36.
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  - Mehta, Rajendra H., Padma Kaul, Renato D. Lopes, Manesh R. Patel, Yinggan Zheng, Karen S. Pieper, Robert C. Welsh, Paul W. Armstrong, and Christopher B. Granger. “Variations in practice and outcomes in patients undergoing primary percutaneous coronary intervention in the United States and Canada: insights from the Assessment of Pexelizumab in Acute Myocardial Infarction (APEX AMI) trial.” Am Heart J 163, no. 5 (May 2012): 797–803. https://doi.org/10.1016/j.ahj.2012.03.001.
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  - Suarez, Jorge, Jonathan P. Piccini, Li Liang, John J. Atherton, Christopher S. Hayward, Henry Krum, Gregg C. Fonarow, Renato D. Lopes, and Adrian F. Hernandez. “International variation in use of oral anticoagulation among heart failure patients with atrial fibrillation.” Am Heart J 163, no. 5 (May 2012): 804–11. https://doi.org/10.1016/j.ahj.2012.02.008.
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  - Fosbol, Emil L., Tracy Y. Wang, Shuang Li, Jonathan P. Piccini, Renato D. Lopes, Bimal Shah, Roger M. Mills, et al. “Safety and effectiveness of antithrombotic strategies in older adult patients with atrial fibrillation and non-ST elevation myocardial infarction.” Am Heart J 163, no. 4 (April 2012): 720–28. https://doi.org/10.1016/j.ahj.2012.01.017.
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  - Armaganijan, Luciana, Dimpi Patel, Renato D. Lopes, Carlos A. Morillo, Roberta R. N. Araújo, Fernando P. Munhoz, Marcelo A. Puzzi, Murilo J. Carvalho, Lilian B. N. Gallo, and Jeff S. Healey. “Gastroesophageal reflux and atrial fibrillation: is there any correlation?” Expert Rev Cardiovasc Ther 10, no. 3 (March 2012): 317–22. https://doi.org/10.1586/erc.11.198.
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  - Lopes, Renato D., Rajendra H. Mehta, Gail E. Hafley, Judson B. Williams, Michael J. Mack, Eric D. Peterson, Keith B. Allen, et al. “Relationship between vein graft failure and subsequent clinical outcomes after coronary artery bypass surgery.” Circulation 125, no. 6 (February 14, 2012): 749–56. https://doi.org/10.1161/CIRCULATIONAHA.111.040311.
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  - Al-Khatib, Sana M., John H. Alexander, Renato D. Lopes, Kenneth W. Mahaffey, Manesh R. Patel, and Christopher B. Granger. “Promise of factor Xa inhibition in atrial fibrillation.” Curr Cardiol Rep 14, no. 1 (February 2012): 70–78. https://doi.org/10.1007/s11886-011-0230-1.
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  - Mehta, Rajendra H., Amanda S. Stebbins, Renato D. Lopes, Robert M. Califf, Karen S. Pieper, Paul W. Armstrong, Frans Van de Werf, et al. “Comparison of incidence of bleeding and mortality of men versus women with ST-elevation myocardial infarction treated with fibrinolysis.” Am J Cardiol 109, no. 3 (February 1, 2012): 320–26. https://doi.org/10.1016/j.amjcard.2011.09.012.
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  - Kociol, Robb D., Renato D. Lopes, Robert Clare, Laine Thomas, Rajendra H. Mehta, Padma Kaul, Karen S. Pieper, et al. “International variation in and factors associated with hospital readmission after myocardial infarction.” Jama 307, no. 1 (January 4, 2012): 66–74. https://doi.org/10.1001/jama.2011.1926.
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  - Kociol, R. D., R. D. Lopes, and M. R. Patel. “In reply.” Jama Journal of the American Medical Association 307, no. 16 (2012): 1691-. https://doi.org/10.1001/jama.2012.531.
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  - Signori, Luis Ulisses, Alexandre Schaan de Quadros, Graciele Sbruzzi, Thiago Dipp, Renato D. Lopes, and Beatriz D’Agord Schaan. “Endothelial function in patients with slow coronary flow and normal coronary angiography.” Clinics (Sao Paulo) 67, no. 6 (2012): 677–80. https://doi.org/10.6061/clinics/2012(06)22.
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  - Lopes, Renato D., John D. Horowitz, David A. Garcia, Mark A. Crowther, and Elaine M. Hylek. “Warfarin and acetaminophen interaction: a summary of the evidence and biologic plausibility.” Blood 118, no. 24 (December 8, 2011): 6269–73. https://doi.org/10.1182/blood-2011-08-335612.
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  - Lopes, Renato D., Bimal R. Shah, DaiWai M. Olson, Xin Zhao, Wenqin Pan, Cheryl D. Bushnell, and Eric D. Peterson. “Antithrombotic therapy use at discharge and 1 year in patients with atrial fibrillation and acute stroke: results from the AVAIL Registry.” Stroke 42, no. 12 (December 2011): 3477–83. https://doi.org/10.1161/STROKEAHA.111.625392.
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  - Lopes, Renato D., and David A. Garcia. “In people with atrial fibrillation unsuitable for warfarin, apixaban reduces the risk of stroke compared with aspirin, with no difference in major bleeding.” Evid Based Med 16, no. 6 (December 2011): 187–88. https://doi.org/10.1136/ebm.2011.0023.
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  - Cecilia Bahit, Maria, Renato D. Lopes, Robert Clare, Karen S. Pieper, L Kristin Newby, Frans Frans Van de Werf, Paul W. Armstrong, et al. “Heart Failure Occurring at any Time During Hospitalization is Associated with Higher Mortality in Non-ST Elevation-Acute Coronary Syndromes.” Circulation 124, no. 21 (November 22, 2011).
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  - Eapen, Zubin, Sana M. Al-Khatib, Yongfei Wang, Renato D. Lopes, Haikun Bao, Jeptha P. Curtis, Paul A. Heidenreich, Adrian F. Hernandez, and Stephen C. Hammill. “Is Cardiac Resynchronization Therapy Use Improving Among Racial/Ethnic Minorities? An Analysis of 107,096 Patients from the NCDR-ICD Registry.” Circulation 124, no. 21 (November 22, 2011).
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  - Giraldez, Roberto R., Robert Clare, Renato D. Lopes, Anthony J. Dalby, Dorairaj Prabhakaran, Gerald X. Brogan, Robert P. Giugliano, et al. “Undiagnosed Diabetes Mellitus, Pre-Diabetes, and Outcomes in Patients with Non-ST-Segment Elevation Acute Coronary Syndromes.” Circulation 124, no. 21 (November 22, 2011).
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  - Guptill, Jeffrey T., Renato D. Lopes, Rajendra H. Mehta, John Horton, Daniel Laskowitz, Karen S. Pieper, Paul W. Armstrong, and Christopher B. Granger. “Most Strokes Occur More Than 48 Hours Following Primary Percutaneous Coronary Intervention in STEMI: the Stroke Experience in APEX-AMI Trial.” Circulation 124, no. 21 (November 22, 2011).
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  - Kuijt, Wichert J., Mitchell W. Krucoff, Peter Damman, Renato D. Lopes, Cindy L. Green, Karen S. Pieper, Susanna R. Stevens, et al. “Prediction of Myocardial Infarct Size Using Multiple Concomitant Angiographic, Biochemical and Electrocardiographic Biomarkers in Patients with ST-Segment Elevation Myocardial Infarction Treated with Primary Percutaneous Coronary Intervention.” Circulation 124, no. 21 (November 22, 2011).
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  - Piccini, Jonathan P., Dajuanicia N. Holmes, Donna M. Ollis, Elizabeth S. Fraulo, Laine Thomas, Jack E. Ansell, Gregg C. Fonarow, et al. “Patterns of Atrial Fibrillation and Treatment Strategies Vary According to Provider Specialty Across Community Practice Settings: Findings From the ORBIT-AF Registry.” Circulation 124, no. 21 (November 22, 2011).
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  - Quadros, Alexandre S., Eduardo Cambruzzi, Renato David, Juliana Sebben, Anibal Abelin, Dulce Welter, Rogerio Sarmento-Leite, Renato D. Lopes, and Carlos A. Gottschall. “Red or White Thrombus in Patients with ST-Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention: Does it Matter?” Circulation 124, no. 21 (November 22, 2011).
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  - Armaganijan, L. V., and R. D. Lopes. “Antithrombotic therapy in patients with ACS and atrial fibrillation: A challenge in clinical practice.” Acute Coronary Syndromes 10, no. 3 (November 17, 2011): 97–102.
  - Fauchier, Laurent, and Nicolas Clementy. “Apixaban after acute coronary syndrome.” N Engl J Med 365, no. 19 (November 10, 2011): 1844. https://doi.org/10.1056/NEJMc1111422.
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  - Horbach, Stevie J., Renato D. Lopes, João C. V. da C Guaragna, Felipe Martini, Rajendra H. Mehta, João B. Petracco, Luis C. Bodanese, et al. “Naproxen as prophylaxis against atrial fibrillation after cardiac surgery: the NAFARM randomized trial.” Am J Med 124, no. 11 (November 2011): 1036–42. https://doi.org/10.1016/j.amjmed.2011.07.026.
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  - Piccini, Jonathan P., Elizabeth S. Fraulo, Jack E. Ansell, Gregg C. Fonarow, Bernard J. Gersh, Alan S. Go, Elaine M. Hylek, et al. “Outcomes registry for better informed treatment of atrial fibrillation: rationale and design of ORBIT-AF.” Am Heart J 162, no. 4 (October 2011): 606-612.e1. https://doi.org/10.1016/j.ahj.2011.07.001.
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  - Granger, Christopher B., John H. Alexander, John J. V. McMurray, Renato D. Lopes, Elaine M. Hylek, Michael Hanna, Hussein R. Al-Khalidi, et al. “Apixaban versus warfarin in patients with atrial fibrillation.” N Engl J Med 365, no. 11 (September 15, 2011): 981–92. https://doi.org/10.1056/NEJMoa1107039.
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  - Lopes, Renato D., Hany Siha, Yuling Fu, Rajendra H. Mehta, Manesh R. Patel, Paul W. Armstrong, and Christopher B. Granger. “Diagnosing acute myocardial infarction in patients with left bundle branch block.” Am J Cardiol 108, no. 6 (September 15, 2011): 782–88. https://doi.org/10.1016/j.amjcard.2011.05.006.
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  - Mehta, Rajendra H., Emily Honeycutt, Uptal D. Patel, Renato D. Lopes, Judson B. Williams, Linda K. Shaw, Sean M. O’Brien, Robert M. Califf, G Chad Hughes, and Michael H. Sketch. “Relationship of the time interval between cardiac catheterization and elective coronary artery bypass surgery with postprocedural acute kidney injury.” Circulation 124, no. 11 Suppl (September 13, 2011): S149–55. https://doi.org/10.1161/CIRCULATIONAHA.110.011700.
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  - Alexander, John H., Renato D. Lopes, Stefan James, Rakhi Kilaru, Yaohua He, Puneet Mohan, Deepak L. Bhatt, et al. “Apixaban with antiplatelet therapy after acute coronary syndrome.” N Engl J Med 365, no. 8 (August 25, 2011): 699–708. https://doi.org/10.1056/NEJMoa1105819.
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  - Lopes, Renato D., Richard C. Becker, John H. Alexander, Paul W. Armstrong, Robert M. Califf, Mark Y. Chan, Mark Crowther, et al. “Highlights from the III International Symposium of Thrombosis and Anticoagulation (ISTA), October 14-16, 2010, São Paulo, Brazil.” J Thromb Thrombolysis 32, no. 2 (August 2011): 242–66. https://doi.org/10.1007/s11239-011-0592-7.
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  - Mehta, R. H., A. Stebbins, R. D. Lopes, R. M. Califf, J. H. Alexander, and C. B. Granger. “Gender paradox: higher incidence but lower one-year mortality with bleeding among women compared with men following fibrinolysis for acute ST-elevation myocardial infarction.” European Heart Journal 32 (August 1, 2011): 166–166.
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  - Mehta, R. H., P. Kaul, R. D. Lopes, M. R. Patel, K. S. Pieper, P. W. Armstrong, and C. B. Granger. “Variations in practice and outcomes in patients undergoing primary percutaneous coronary intervention in the United States and Canada: insights from the APEX-AMI trial.” European Heart Journal 32 (August 1, 2011): 872–872.
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  - Suarez, Jorge, Jonathan P. Piccini, Li Liang, John J. Atherton, Christopher S. Haywood, Renato D. Lopes, and Adrian F. Hernandez. “International Variation in Use of Anticoagulation among Heart Failure Patients with Atrial Fibrillation.” Journal of Cardiac Failure 17, no. 8 (August 2011): S72–S72. https://doi.org/10.1016/j.cardfail.2011.06.243.
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  - Mehta, Rajendra H., T Bruce Ferguson, Renato D. Lopes, Gail E. Hafley, Michael J. Mack, Nicholas T. Kouchoukos, C Michael Gibson, et al. “Saphenous vein grafts with multiple versus single distal targets in patients undergoing coronary artery bypass surgery: one-year graft failure and five-year outcomes from the Project of Ex-Vivo Vein Graft Engineering via Transfection (PREVENT) IV trial.” Circulation 124, no. 3 (July 19, 2011): 280–88. https://doi.org/10.1161/CIRCULATIONAHA.110.991299.
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  - Leiria, Tiago L. L., Renato D. Lopes, Judson B. Williams, Jason N. Katz, Renato A. K. Kalil, and John H. Alexander. “Antithrombotic therapies in patients with prosthetic heart valves: guidelines translated for the clinician.” J Thromb Thrombolysis 31, no. 4 (May 2011): 514–22. https://doi.org/10.1007/s11239-011-0574-9.
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  - Leonardi, Sergio, Laine Thomas, Megan L. Koehler, Pierluigi Tricoci, Renato D. Lopes, Harvey D. White, Paul W. Armstrong, and L Kristin Newby. “WHAT THRESHOLD SHOULD BE USED TO DEFINE PERCUTANEOUS CORONARY INTERVENTION-RELATED MYOCARDIAL INFARCTION? AN APPROACH BASED ON CLINICAL RELEVANCE FROM EARLY ACS AND SYNERGY.” Journal of the American College of Cardiology 57, no. 14 (April 2011): E1239–E1239. https://doi.org/10.1016/s0735-1097(11)61239-4.
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  - Lopes, Renato D. “Antiplatelet agents in cardiovascular disease.” Journal of Thrombosis and Thrombolysis 31, no. 3 (April 2011): 306–9. https://doi.org/10.1007/s11239-011-0558-9.
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  - Mehta, Rajendra H., Aijing Z. Starr, Renato D. Lopes, Jonathan P. Piccini, Manesh R. Patel, Karen S. Pieper, Paul W. Armstrong, and Christopher B. Granger. “Relationship of sustained ventricular tachyarrhythmias to outcomes in patients undergoing primary percutaneous coronary intervention with varying underlying baseline risk.” Am Heart J 161, no. 4 (April 2011): 782–89. https://doi.org/10.1016/j.ahj.2011.01.005.
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  - Gharacholou, S Michael, Renato D. Lopes, Karen P. Alexander, Rajendra H. Mehta, Amanda L. Stebbins, Karen S. Pieper, Stefan K. James, Paul W. Armstrong, and Christopher B. Granger. “Age and outcomes in ST-segment elevation myocardial infarction treated with primary percutaneous coronary intervention: findings from the APEX-AMI trial.” Arch Intern Med 171, no. 6 (March 28, 2011): 559–67. https://doi.org/10.1001/archinternmed.2011.36.
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  - Quadros, Alexandre S., Dulce I. Welter, Fernanda O. Camozzatto, Aurea Chaves, Rajendra H. Mehta, Carlos A. Gottschall, and Renato D. Lopes. “Identifying patients at risk for premature discontinuation of thienopyridine after coronary stent implantation.” Am J Cardiol 107, no. 5 (March 1, 2011): 685–89. https://doi.org/10.1016/j.amjcard.2010.10.045.
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  - Armaganijan, Luciana, Renato D. Lopes, Jeff S. Healey, Jonathan P. Piccini, Girish M. Nair, and Carlos A. Morillo. “Do omega-3 fatty acids prevent atrial fibrillation after open heart surgery? A meta-analysis of randomized controlled trials.” Clinics (Sao Paulo) 66, no. 11 (2011): 1923–28. https://doi.org/10.1590/s1807-59322011001100012.
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  - Gualandro, Danielle Menosi, Pai Ching Yu, Daniela Calderaro, André C. Marques, Claudio Pinho, Bruno Caramelli, Alina Coutinho Rodrigues Feitosa, et al. “II Guidelines for perioperative evaluation of the Brazilian Society of Cardiology.” Arq Bras Cardiol 96, no. 3 Suppl 1 (2011): 1–68.
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  - Mehta, Rajendra H., Amanda Stebbins, Renato D. Lopes, Sunil V. Rao, Eric R. Bates, Karen S. Pieper, Paul W. Armstrong, et al. “Race, Bleeding, and Outcomes in STEMI Patients Treated with Fibrinolytic Therapy.” Am J Med 124, no. 1 (January 2011): 48–57. https://doi.org/10.1016/j.amjmed.2010.07.028.
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  - Stashenko, Gregg, Renato D. Lopes, David Garcia, John H. Alexander, and Victor F. Tapson. “Prophylaxis for venous thromboembolism: guidelines translated for the clinician.” J Thromb Thrombolysis 31, no. 1 (January 2011): 122–32. https://doi.org/10.1007/s11239-010-0522-0.
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  - Mehta, Rajendra H., Emily Honeycutt, Uptal D. Patel, Renato D. Lopes, Linda K. Shaw, Donald D. Glower, Robert A. Harrington, Robert M. Califf, and Michael H. Sketch. “Impact of recovery of renal function on long-term mortality after coronary artery bypass grafting.” Am J Cardiol 106, no. 12 (December 15, 2010): 1728–34. https://doi.org/10.1016/j.amjcard.2010.07.045.
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  - Chan, Mark Y., Jie L. Sun, Tracy Y. Wang, Renato D. Lopes, Marc E. Jolicoeur, Karen S. Pieper, Sunil V. Rao, et al. “Patterns of discharge antiplatelet therapy and late outcomes among 8,582 patients with bleeding during acute coronary syndrome: a pooled analysis from PURSUIT, PARAGON-A, PARAGON-B, and SYNERGY.” Am Heart J 160, no. 6 (December 2010): 1056-1064.e2. https://doi.org/10.1016/j.ahj.2010.09.001.
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  - Garcia, David A., Renato D. Lopes, and Elaine M. Hylek. “New-onset atrial fibrillation and warfarin initiation: high risk periods and implications for new antithrombotic drugs.” Thromb Haemost 104, no. 6 (December 2010): 1099–1105. https://doi.org/10.1160/TH10-07-0491.
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  - Leonardi, Sergio, Amanda Stebbins, Renato D. Lopes, Yuliya Lokhnygina, Deepak L. Bhatt, Gregg W. Stone, Michael A. Lincoff, et al. “Pre-Treatment With Thienopyridines Reduces The Amount of Myonecrosis in Acute Coronary Syndrome Patients Invasively Managed: Insights from the CHAMPION trials.” Circulation 122, no. 21 (November 23, 2010).
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  - Lopes, Renato D., Jennifer A. White, Pierluigi Tricoci, Harvey D. White, Paul W. Armstrong, Eugene Braunwald, Robert P. Giugliano, et al. “More Bleeding but No Additional Efficacy with Increasing Age in High-risk ACS Patients Treated with Early vs. Delayed, Provisional Eptifibatide.” Circulation 122, no. 21 (November 23, 2010).
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  - Lopes, Renato D., Li Li, Christopher B. Granger, Tracy Y. Wang, JoAnne M. Foody, Marjorie Funk, Eric D. Peterson, and Karen P. Alexander. “Discharge Warfarin is Underused in High Risk Atrial Fibrillation Patients With Myocardial Infarction.” Circulation 122, no. 21 (November 23, 2010).
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  - Kong, Melissa H., Renato D. Lopes, Jonathan P. Piccini, Vic Hasselblad, Tristram D. Bahnson, and Sana M. Al-Khatib. “Surgical Maze procedure as a treatment for atrial fibrillation: a meta-analysis of randomized controlled trials.” Cardiovasc Ther 28, no. 5 (October 2010): 311–26. https://doi.org/10.1111/j.1755-5922.2010.00139.x.
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  - Flato, Uri Adrian Prync, Hélio Penna Guimarães, Renato Delascio Lopes, Jorge Luís Valiatti, Elias Marcos Silva Flato, and Ricardo Gonçalves Lorenzo. “Usefulness of Extended-FAST (EFAST-Extended Focused Assessment with Sonography for Trauma) in critical care setting.” Rev Bras Ter Intensiva 22, no. 3 (September 2010): 291–99. https://doi.org/10.1590/s0103-507x2010000300012.
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  - Batista, M. L., R. D. Lopes, M. C. L. Seelaender, and A. C. Lopes. “Anti-inflammatory effect of physical training in heart failure: Role of TNF-α and IL-10 (Arquivos Brasileiros de Cardiologia (2009) 93, 6, (692-700)).” Arquivos Brasileiros De Cardiologia 95, no. 2 (August 1, 2010): 279. https://doi.org/10.1590/S0066-782X2010001200022.
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  - Lopes, R. D., M. L. Batista, J. C. Rosa, F. S. De Lira, E. Martins, A. Y. Shimura, P. C. Brum, A. H. Lancha, M. C. L. Seelaender, and A. C. Lopes. “Changes in the production of IL-10 and TNF-α in skeletal muscle of rats with heart failure secondary to acute myocardial infarction (Arquivos Brasileiros de Cardiologia (2010) 94, 3, (313-320)).” Arquivos Brasileiros De Cardiologia 95, no. 2 (August 1, 2010): 279. https://doi.org/10.1590/S0066-782X2010001200023.
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  - Diepen, Sean van, Hany Siha, Yuling Fu, Cynthia M. Westerhout, Renato D. Lopes, Christopher B. Granger, Paul W. Armstrong, and Paul W. APEX AMI Investigators. “Do baseline atrial electrocardiographic and infarction patterns predict new-onset atrial fibrillation after ST-elevation myocardial infarction? Insights from the Assessment of Pexelizumab in Acute Myocardial Infarction Trial.” J Electrocardiol 43, no. 4 (July 2010): 351–58. https://doi.org/10.1016/j.jelectrocard.2010.04.001.
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  - Piccini, Jonathan P., Renato D. Lopes, and Kenneth W. Mahaffey. “Oral factor Xa inhibitors for the prevention of stroke in atrial fibrillation.” Curr Opin Cardiol 25, no. 4 (July 2010): 312–20. https://doi.org/10.1097/HCO.0b013e32833a524f.
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  - Lopes, Renato D., Eric D. Peterson, Anita Y. Chen, Matthew T. Roe, Tracy Y. Wang, E Magnus Ohman, David J. Magid, et al. “Antithrombotic strategy in non-ST-segment elevation myocardial infarction patients undergoing percutaneous coronary intervention: insights from the ACTION (Acute Coronary Treatment and Intervention Outcomes Network) Registry.” Jacc Cardiovasc Interv 3, no. 6 (June 2010): 669–77. https://doi.org/10.1016/j.jcin.2010.03.015.
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  - Gharacholou, S Michael, Renato D. Lopes, Jeffrey B. Washam, L Kristin Newby, Stefan K. James, and John H. Alexander. “Antithrombotic therapy in acute coronary syndromes: guidelines translated for the clinician.” J Thromb Thrombolysis 29, no. 4 (May 2010): 516–28. https://doi.org/10.1007/s11239-009-0437-9.
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  - Lopes, Renato D., David Garcia, Richard C. Becker, Christopher B. Granger, L Kristin Newby, John H. Alexander, E Marc Jolicoeur, et al. “Highlights from the II International Symposium of Thrombosis and Anticoagulation (ISTA), October 22-23, 2009, São Paulo, Brazil.” J Thromb Thrombolysis 29, no. 4 (May 2010): 395–408. https://doi.org/10.1007/s11239-010-0454-8.
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  - Krishnan, Anandi, Renato D. Lopes, John H. Alexander, Richard C. Becker, and Larry B. Goldstein. “Antithrombotic therapy for ischemic stroke: guidelines translated for the clinician.” J Thromb Thrombolysis 29, no. 3 (April 2010): 368–77. https://doi.org/10.1007/s11239-010-0439-7.
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  - Lopes, Renato D., John H. Alexander, Sana M. Al-Khatib, Jack Ansell, Raphael Diaz, J Donald Easton, Bernard J. Gersh, et al. “Apixaban for reduction in stroke and other ThromboemboLic events in atrial fibrillation (ARISTOTLE) trial: design and rationale.” Am Heart J 159, no. 3 (March 2010): 331–39. https://doi.org/10.1016/j.ahj.2009.07.035.
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  - Lopes, Renato Delacio, Miguel Luiz Batista, José Cesar Rosa, Fabio Santos de Lira, Eivor Martins, Alex Yamashita Shimura, Patrícia Chakur Brum, Antonio Herbert Lancha, Marília C. L. Seelaender, and Antonio Carlos Lopes. “Changes in the production of IL-10 and TNF-alpha in skeletal muscle of rats with heart failure secondary to acute myocardial infarction.” Arq Bras Cardiol 94, no. 3 (March 2010): 293–320. https://doi.org/10.1590/s0066-782x2010000300006.
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  - Lopes, Renato D., Aijing Starr, Carl F. Pieper, Sana M. Al-Khatib, L Kristin Newby, Rajendra H. Mehta, Frans Van de Werf, et al. “Warfarin use and outcomes in patients with atrial fibrillation complicating acute coronary syndromes.” Am J Med 123, no. 2 (February 2010): 134–40. https://doi.org/10.1016/j.amjmed.2009.09.015.
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  - Batista, M. L., J. C. Rosa, R. D. Lopes, F. S. Lira, E. Martins, A. S. Yamashita, P. C. Brum, A. H. Lancha, A. C. Lopes, and M. Seelaender. “Exercise training changes IL-10/TNF-alpha ratio in the skeletal muscle of post-MI rats.” Cytokine 49, no. 1 (January 2010): 102–8. https://doi.org/10.1016/j.cyto.2009.10.007.
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  - Lopes, Renato D., and Christopher B. Granger. “Interpreting the TRITON results in light of the event adjudication process.” Cardiology 115, no. 2 (2010): 89–90. https://doi.org/10.1159/000256383.
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  - Mehta, Rajendra H., Renato D. Lopes, Andrea Ballotta, Alessandro Frigiola, Michael H. Sketch, Eduardo Bossone, and Eric R. Bates. “Percutaneous coronary intervention or coronary artery bypass surgery for cardiogenic shock and multivessel coronary artery disease?” Am Heart J 159, no. 1 (January 2010): 141–47. https://doi.org/10.1016/j.ahj.2009.10.035.
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  - Batista, Miguel Luiz, Renato Delascio Lopes, Marília Cerqueira Leite Seelaender, and Antonio Carlos Lopes. “Anti-inflammatory effect of physical training in heart failure: role of TNF-alpha and IL-10.” Arq Bras Cardiol 93, no. 6 (December 2009): 643–700.
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  - Júnior, M. L. B., R. D. Lopes, M. C. L. Seelaender, and A. C. Lopes. “Antiinflammatory effect of physical training in heart failure: Role of TNF-α and IL-10.” Arquivos Brasileiros De Cardiologia 93, no. 6 (December 1, 2009).
  - Lopes, R. D., and C. B. Granger. “β-blockers in myocardial infarction: An overview.” Acute Coronary Syndromes 9, no. 4 (December 1, 2009): 141–47.
  - Lopes, R. D., and C. B. Granger. “Highlights from the American Heart Association (AHA) Scientific Sessions 2008.” Acute Coronary Syndromes 9, no. 3 (December 1, 2009): 121–24.
  - Piccini, Jonathan P., Renato D. Lopes, Melissa H. Kong, Vic Hasselblad, Kevin Jackson, and Sana M. Al-Khatib. “Pulmonary vein isolation for the maintenance of sinus rhythm in patients with atrial fibrillation: a meta-analysis of randomized, controlled trials.” Circ Arrhythm Electrophysiol 2, no. 6 (December 2009): 626–33. https://doi.org/10.1161/CIRCEP.109.856633.
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  - Lopes, Renato D., John H. Alexander, and T Bruce Ferguson. “Endoscopic versus Open Vein-Graft Harvesting REPLY.” New England Journal of Medicine 361, no. 19 (November 5, 2009): 1909–10.
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  - Lopes, Renato D., E Magnus Ohman, Christopher B. Granger, Emily F. Honeycutt, Kevin J. Anstrom, Peter B. Berger, Eric M. Crespo, et al. “Six-month follow-up of patients with in-hospital thrombocytopenia during heparin-based anticoagulation (from the Complications After Thrombocytopenia Caused by Heparin [CATCH] registry).” Am J Cardiol 104, no. 9 (November 1, 2009): 1285–91. https://doi.org/10.1016/j.amjcard.2009.06.045.
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  - Houman Fekrazad, M., Renato D. Lopes, Gregg J. Stashenko, John H. Alexander, and David Garcia. “Treatment of venous thromboembolism: guidelines translated for the clinician.” J Thromb Thrombolysis 28, no. 3 (October 2009): 270–75. https://doi.org/10.1007/s11239-009-0374-7.
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  - Lopes, Renato D., and Karen P. Alexander. “Antiplatelet therapy in older adults with non-ST-segment elevation acute coronary syndrome: considering risks and benefits.” Am J Cardiol 104, no. 5 Suppl (September 7, 2009): 16C-21C. https://doi.org/10.1016/j.amjcard.2009.06.021.
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  - Lopes, Renato D., Laine E. Elliott, Harvey D. White, Judith S. Hochman, Frans Van de Werf, Diego Ardissino, Torsten T. Nielsen, et al. “Antithrombotic therapy and outcomes of patients with atrial fibrillation following primary percutaneous coronary intervention: results from the APEX-AMI trial.” Eur Heart J 30, no. 16 (August 2009): 2019–28. https://doi.org/10.1093/eurheartj/ehp213.
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  - Lopes, Renato D., Gail E. Hafley, Keith B. Allen, T Bruce Ferguson, Eric D. Peterson, Robert A. Harrington, Rajendra H. Mehta, et al. “Endoscopic versus open vein-graft harvesting in coronary-artery bypass surgery.” N Engl J Med 361, no. 3 (July 16, 2009): 235–44. https://doi.org/10.1056/NEJMoa0900708.
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  - Kraai, Erik P., Renato D. Lopes, John H. Alexander, and David Garcia. “Perioperative management of anticoagulation: guidelines translated for the clinician.” J Thromb Thrombolysis 28, no. 1 (July 2009): 16–22. https://doi.org/10.1007/s11239-009-0313-7.
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  - Lopes, Renato D., Richard C. Becker, David Garcia, Elaine M. Hylek, Christopher B. Granger, Dayse M. Lourenço, Helena B. Nader, et al. “Highlights from the I international symposium of thrombosis and anticoagulation in internal medicine, October 23-25, 2008, Sao Paulo, Brazil.” J Thromb Thrombolysis 28, no. 1 (July 2009): 106–16. https://doi.org/10.1007/s11239-009-0324-4.
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  - Mehta, Rajendra H., Aijing Z. Starr, Renato D. Lopes, Judith S. Hochman, Petr Widimsky, Karen S. Pieper, Paul W. Armstrong, Christopher B. Granger, and Christopher B. APEX AMI Investigators. “Incidence of and outcomes associated with ventricular tachycardia or fibrillation in patients undergoing primary percutaneous coronary intervention.” Jama 301, no. 17 (May 6, 2009): 1779–89. https://doi.org/10.1001/jama.2009.600.
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  - Lopes, Renato D., Karen P. Alexander, Steven V. Manoukian, Michel E. Bertrand, Frederick Feit, Harvey D. White, Charles V. Pollack, et al. “Advanced age, antithrombotic strategy, and bleeding in non-ST-segment elevation acute coronary syndromes: results from the ACUITY (Acute Catheterization and Urgent Intervention Triage Strategy) trial.” J Am Coll Cardiol 53, no. 12 (March 24, 2009): 1021–30. https://doi.org/10.1016/j.jacc.2008.12.021.
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  - Kong, Melissa H., Renato D. Lopes, Jonathan P. Piccini, Vic Hasselblad, Tristram D. Bahnson, and Sana M. Al-Khatib. “Surgical Maze Procedure as a Treatment for Atrial Fibrillation: A Meta-Analysis of Randomized Controlled Trials.” Journal of the American College of Cardiology 53, no. 10 (March 10, 2009): A118–A118.
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  - Lopes, Renato D., Aijing Starr, Sana M. Al-Khatib, L Kristin Newby, Rajendra H. Mehta, Frans Van de Werf, Kenneth W. Mahaffey, et al. “Warfarin Is Independently Associated With Lower Risk of Six-Month Death or Myocardial Infarction in Patients With Atrial Fibrillation Following Acute Coronary Syndromes.” Journal of the American College of Cardiology 53, no. 10 (March 10, 2009): A354–A354.
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  - Lopes, Renato D., Hany Siha, Yuling Fu, Paul W. Armstrong, and Christopher B. Granger. “Left Bundle Branch Block Without Concordant ST-Elevation In Suspected ST-Elevation Myocardial Infarction Identifies Patients With High False Positive Rates: Insights From the APEX-AMI Trial.” Journal of the American College of Cardiology 53, no. 10 (March 10, 2009): A323–A323.
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  - Feitosa-Filho, Gilson Soares, Joberto Pinheiro Sena, Hélio Penna Guimarães, and Renato Delascio Lopes. “Therapeutical hypothermia after cardiopulmonary resuscitation: evidences and practical issues.” Rev Bras Ter Intensiva 21, no. 1 (March 2009): 65–71.
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  - Lira, Fábio S., José C. Rosa, Nelo E. Zanchi, Alex S. Yamashita, Renato D. Lopes, Antonio C. Lopes, Miguel L. Batista, and Marília Seelaender. “Regulation of inflammation in the adipose tissue in cancer cachexia: effect of exercise.” Cell Biochem Funct 27, no. 2 (March 2009): 71–75. https://doi.org/10.1002/cbf.1540.
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  - Belfort, Rubens N., Bruno F. Fernandes, André Romano, Ricardo Nose, Jonathan Cools-Lartigue, Eduardo V. Navajas, Garles Mm Vieira, Renato Delascio Lopes, and Rubens Belfort. “Bilateral macular hemorrhage as a complication of drug-induced anemia: a case report.” J Med Case Rep 3 (January 13, 2009): 16. https://doi.org/10.1186/1752-1947-3-16.
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  - Lópes, R. D., M. Chan, and L. K. Newby. “Novel Markers in Patients with Suspected Acute Coronary Syndromes,” January 13, 2009, 75–92. https://doi.org/10.1002/9781444300208.ch5.
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  - Lopes, R. D., E. M. Jolicoeur, and M. Y. Chan. “Hyporesponsivity to antiplatelet therapy.” Revista Brasileira De Cardiologia Invasiva 17, no. 4 (January 1, 2009): 450–52.
  - Lopes, Renato D., Jonathan P. Piccini, Elaine M. Hylek, Christopher B. Granger, and John H. Alexander. “Antithrombotic therapy in atrial fibrillation: guidelines translated for the clinician.” J Thromb Thrombolysis 26, no. 3 (December 2008): 167–74. https://doi.org/10.1007/s11239-008-0272-4.
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  - Lopes, Renato D., Christopher B. Granger, Emily F. Honeycutt, Eric M. Crespo, Kevin J. Anstrom, E Magnus Ohman, and Richard C. Becker. “Patients with Thrombocytopenia following Heparin Therapy Have Early but not Late Risk of Death: Results from the CATCH Registry.” Circulation 118, no. 18 (October 28, 2008): S1052–S1052.
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  - Mehta, Rajendra H., Aijing Z. Starr, Renato D. Lopes, Karen S. Pieper, Paul W. Armstrong, and Christopher B. Granger. “Association of Sustained Ventricular Tachycardia/Fibrillation and the Timing of its Occurrence on Outcomes in Patients Undergoing Primary Percutaneous Coronary Interventions: Insights from the APEX-AMI Trial.” Circulation 118, no. 18 (October 28, 2008): S1058–S1058.
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  - Lopes, R. D., G. E. Hafley, K. B. Allen, T. B. Ferguson, E. D. Peterson, R. A. Harrington, N. T. Kouchoukos, C. M. Gibson, and J. H. Alexander. “Endoscopic vein harvesting is a strong independent predictor of vein graft failure in patients undergoing coronary artery bypass graft surgery.” European Heart Journal 29 (September 1, 2008): 284–85.
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  - Lopes, Renato D., Karen P. Alexander, Gretchen Marcucci, Harvey D. White, Sarah Spinler, Jacques Col, Philip E. Aylward, Robert M. Califf, and Kenneth W. Mahaffey. “Outcomes in elderly patients with acute coronary syndromes randomized to enoxaparin vs. unfractionated heparin: results from the SYNERGY trial.” Eur Heart J 29, no. 15 (August 2008): 1827–33. https://doi.org/10.1093/eurheartj/ehn236.
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  - Lopes, R. D., K. S. Pieper, J. R. Horton, S. M. Al-Khatib, L. K. Newby, R. H. Mehta, F. Van de Werf, et al. “Short- and long-term outcomes following atrial fibrillation in patients with acute coronary syndromes with or without ST-segment elevation.” Heart 94, no. 7 (July 2008): 867–73. https://doi.org/10.1136/hrt.2007.134486.
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  - Lopes, R. D., M. Chan, C. Melloni, E. M. Jolicoeur, L. A. Allen, B. R. Shah, J. N. Katz, J. S. Berger, and J. P. Piccini. “Late-breaking trials summary from the 2008 American College of Cardiology Scientific Sessions, March 29 to April 1, Chicago, IL.” American Heart Journal 156, no. 1 (July 1, 2008): 7–12. https://doi.org/10.1016/j.ahj.2008.04.008.
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  - Batista, Mariana Dias, Daniela Takano, Renato Delascio Lopes, Milvia M. S. S. Enokihara, Nilceo Schwery Michalany, and Fernando Augusto de Almeida. “Paraneoplastic pemphigus associated with non-Hodgkin lymphoma.” Dermatol Online J 14, no. 6 (June 15, 2008): 11.
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  - Allen, Larry A., E Marc Jolicoeur, Chiara Melloni, Renato D. Lopes, Mark Y. Chan, Mohamed Majidi, Jonathan P. Piccini, Jeffrey S. Berger, Jason N. Katz, and Bimal R. Shah. “Highlights from American Heart Association, November 4-7, 2007, Orlando, Florida, USA. Late-breaking trials summary.” Am Heart J 155, no. 4 (April 2008): 615–23. https://doi.org/10.1016/j.ahj.2007.12.001.
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  - Batista, Miguel Luiz, Ronaldo V. T. Santos, Renato D. Lopes, Antônio C. Lopes, Luís Fernando B. P. Costa Rosa, and Marília C. L. Seelaender. “Endurance training modulates lymphocyte function in rats with post-MI CHF.” Med Sci Sports Exerc 40, no. 3 (March 2008): 549–56. https://doi.org/10.1249/MSS.0b013e31815ed6d2.
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  - Lopes, Renato D., Kenneth Mahaffey, Robert A. Harrington, John Horton, Paul Armstrong, Kristin Newby, Magnus Ohman, et al. “Atrial fibrillation is independently associated with a high risk of death in patients with acute coronary syndromes.” Circulation 116, no. 16 (October 16, 2007): 315–315.
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  - Jolicoeur, E Marc, Tracy Wang, Renato D. Lopes, and E Magnus Ohman. “Percutaneous coronary interventions in patients with heparin-induced thrombocytopenia.” Curr Cardiol Rep 9, no. 5 (September 2007): 396–405. https://doi.org/10.1007/BF02938367.
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  - Lopes, R. D., G. Marcucci, H. D. White, S. A. Spinler, J. Col, D. C. Gulba, P. E. Aylward, R. M. Califf, J. J. Ferguson, and K. W. Mahaffey. “Similar association between age and outcomes in high-risk ACS patients treated with enoxaparin or unfractionated heparin.” European Heart Journal 28 (September 1, 2007): 218–218.
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  - Lopes, R. D., K. M. Mahaffey, R. H. Harrington, L. L. Lan, P. A. Armstrong, K. N. Newby, M. O. Ohman, F. V. W. Van de Werf, S. A. K. Al-Khatib, and C. B. G. Granger. “Atrial fibrillation is associated with worse outcomes in ST elevation and non ST elevation acute coronary syndromes.” European Heart Journal 28 (September 1, 2007): 259–60.
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  - Adams, George L., James S. Mills, Chiara Melloni, Larry A. Allen, E Marc Jolicoeur, Tracy Wang, Mark Chan, Mohamed Majidi, and Renato D. Lopes. “Highlights from the 56th annual scientific sessions of the American College of Cardiology: March 25 to 27, 2007, Atlanta, Georgia.” Am Heart J 154, no. 2 (August 2007): 247–59. https://doi.org/10.1016/j.ahj.2007.05.005.
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  - Lopes, Renato Delascio, Lindalva Batista Neves, Vânia D’Almeida, Gleice Margarete de Souza Conceição, and Alexandre Gabriel. “Total plasmatic homocysteine and von Willebrand factor in experimental diabetes mellitus.” Arq Bras Cardiol 88, no. 4 (April 2007): 424–29. https://doi.org/10.1590/s0066-782x2007000400010.
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  - Lopes, R. D., L. B. Neves, V. D’Almeida, G. M. D. S. Conceição, and A. G. Jr. “Total plasmatic homocysteine and von Willebrand factor in experimental diabetes mellitus.” Arquivos Brasileiros De Cardiologia 88, no. 4 (2007): 373-377+424-429.
  - Hira, A. Y., A. Nebel de Mello, R. A. Faria, V. Odone Filho, R. D. Lopes, and M. K. Zuffo. “Development of a telemedicine model for emerging countries: a case study on pediatric oncology in Brazil.” Conf Proc Ieee Eng Med Biol Soc 2006 (2006): 5252–56. https://doi.org/10.1109/IEMBS.2006.259380.
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  - Santos, Ina S., Jose Boccio, Ari S. Santos, Neiva C. J. Valle, Camila S. Halal, Marta Colvara Bachilli, and Ricardo D. Lopes. “Prevalence of Helicobacter pylori infection and associated factors among adults in Southern Brazil: a population-based cross-sectional study.” Bmc Public Health 5 (November 10, 2005): 118. https://doi.org/10.1186/1471-2458-5-118.
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  - Góes, V. P., L. S. Machado, M. C. Cabral, R. B. Leitão, R. D. Lopes, and M. K. Zuffo. “Interactive stereoscopic full-color direct volume visualization for virtual reality applications in medicine.” Stud Health Technol Inform 81 (2001): 161–67.
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  - Machado, L. S., A. N. de Mello, R. D. Lopes, V. Odone Filho, and M. K. Zuffo. “A virtual reality simulator for bone marrow harvest for pediatric transplant.” Stud Health Technol Inform 81 (2001): 293–97.
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  - Liberatori Filho, A. W., R. D. Lopes, O. A. Mora, M. J. Simões, and A. C. Lopes. “[Histomorphometric study of cardiomyocytes of the left ventricle of pregnant albino rats].” Rev Assoc Med Bras (1992) 45, no. 3 (July 1999): 242–46. https://doi.org/10.1590/s0104-42301999000300009.
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- Book Sections
  - Compton, S. N., M. A. Villabø, and H. Kristensen. “Introduction.” In Pediatric Anxiety Disorders, 3–5, 2019. https://doi.org/10.1016/B978-0-12-813004-9.00001-3.
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  - De Carvalho, A. C. C., R. D. Lopes, and A. A. V. de Paola. “Atrial fibrillation and stroke prevention.” In Prevention of Cardiovascular Diseases: From Current Evidence to Clinical Practice, 261–76, 2015. https://doi.org/10.1007/978-3-319-22357-5_25.
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  - Berwanger, O., A. Biasi, and R. D. Lopes. “Designing Clinical Trials in Cardiology.” In Intensive Care in Cardiology, edited by E. Knobel. Atheneu, 2015.
  - Brito, F. S., and R. D. Lopes. “Antithrombotic Therapy in Cardiology.” In Intensive Care in Cardiology, edited by E. Knobel. Atheneu, 2015.
  - Pesaro, A. E. P., and R. D. Lopes. “Non-ST Elevation Acute Coronary Syndrome.” In Intensive Care in Cardiology, edited by E. Knobel. Atheneu, 2015.
  - Barros e Silva, P. G. M., and R. D. Lopes. “Cardiac Cycle and Importance of Physical Examination.” In Cardiology, edited by MdCV Moreira, S. T. Montenegro, and A. A. de Paola. Manole: Brazilian Society of Cardiology, 2014.
  - Brito, F. S., R. D. Lopes, and M. T. Roe. “Atherothrombosis.” In Clinical Practice, edited by D. L. Bhatt. Oxford American Cardiovascular Library, 2013.
  - Reist, C. J., T. L. Rorick, L. G. Berdan, and R. D. Lopes. “The Role of Academic Research Organizations in Clinical Research.” In Understanding Clinical Trials, edited by R. D. Lopes and R. A. Harrington. New York: McGraw-Hill, 2013.
  - Lopes, R. D., M. Chan, and L. K. Newby. “Novel Markers in Patients with Suspected ACS.” In Biomarkers in Heart Disease, edited by J. A. De Lemos. American Heart Association, 2008.
  - Lopes, A. C., and R. D. Lopes. “Arterial High Blood Pressure.” In Emergency Medicine Manual, edited by A. C. Lopes, M. ElenaGuariento, and L. Ward. Editora Atheneu, 2006.
  - Lopes, R. D., and H. P. Guimaraes. “Acid-base and Hydro-electrolytic Balance.” In Clinical Toxicology Fundamentals, edited by S. Graff and A. C. Lopes. Editora Atheneu, 2006.
  - Costa, M. P. F., H. P. Guimaraes, and R. D. Lopes. “Defibrillation and Electric.” In Cardio Respiratory Stroke, 65–73. Editora Atheneu, 2005.
  - Feitosa Filho, G. S., and R. D. Lopes. “Therapeutic Hypothermia in Brain-Cardio Pulmonary Resuscitation.” In Cardio Respiratory Stroke, 105–12. Editora Atheneu, 2005.
  - Fonsecca, M. A. J., R. D. Lopes, and F. R. B. Marques. “Crucial Algorithms to the Assistance to Cardio Respiratory Stroke.” In Cardio Respiratory Stroke, 161–64. Editora Atheneu, 2005.
  - Gomes, E. P., V. N. Siqueira, and R. D. Lopes. “Asystole.” In Cardio Respiratory Stroke, 43–48. Editora Atheneu, 2005.
  - Guimaraes, H. P., N. Filgueiras, and R. D. Lopes. “Cardio Pulmonary and Brain Resuscitation.” In Introduction to Intensive Medicine, edited by H. P. Guimaraes and A. M. D. A. Ferreira, 1:9–34. Sao Paulo, Brazil, 2005.
  - Guimaraes, H. P., R. D. Lopes, L. F. R. Falcão, and L. E. J. Segovia. “Definition, Levels of Evidence and Diagnosis.” In Cardio Respiratory Stroke, 1–5. Editora Atheneu, 2005.
  - Guimaraes, H. P., R. D. Lopes, and G. K. Barcelos. “Internal and Transvein Pacemaker.” In Cardio Respiratory Stroke, 91–97. Editora Atheneu, 2005.
  - Guimaraes, H. P., R. D. Lopes, and M. P. Costa. “Basic Life Support (SBV).” In Cardio Respiratory Stroke, 7–35. Editora Atheneu, 2005.
  - Guimaraes, H. P., and R. D. Lopes. “Cardio Pulmonary Evaluation previous to exercises.” In The Exercise as Therapy in Practical Medicine, edited by M. Vaisberg, F. B. P. C. Rosa, and M. T. de Mello, 1:27–35. Sao Paulo, Brazil, 2005.
  - Lopes, R. D. “Conclusion.” In Acid-Base and Hydro-Electrolytic Balance, 79–79. Editora Atheneu, 2005.
  - Lopes, R. D., M. J. B. Silva, and V. L. D. Rego. “Primary Disturbances.” In Acid-Base and Hydro-Electrolytic Balance, 13–54. Editora Atheneu, 2005.
  - Lopes, R. D., V. L. D. Rego, and M. J. B. Silva. “Clinical Cases.” In Acid-Base and Hydro-Electrolytic Balance, 69–78. Editora Atheneu, 2005.
  - Lopes, R. D., and H. P. Guimaraes. “Ventricular Fibrillation (FV) and Ventricular Palpitation (TV) without Pulse.” In Cardio Respiratory Stroke, 37–42. Editora Atheneu, 2005.
  - Rego, V. L. D., and R. D. Lopes. “Secondary Disturbances (compensations) and Mixed.” In Acid-Base and Hydro-Electrolytic Balance, 55–59. Editora Atheneu, 2005.
  - Silva, M. J. B., R. D. Lopes, and H. P. Guimaraes. “Systematic Approach of the Acid – base disturbances and Arterial Gas.” In Acid-Base and Hydro-Electrolytic Balance, 61–67. Editora Atheneu, 2005.
  - Siqueira, V. N., J. S. Mossini, H. P. Guimaraes, and R. D. Lopes. “Drug Doses and Administration Modes.” In Cardio Respiratory Stroke, 165–73. Editora Atheneu, 2005.
  - Lopes, A. C., A. W. Liberatori Filho, and R. D. Lopes. “Non- Toxic High Blood Pressure Treatment during pregnancy,” 171–75. Sao Paulo, Brazil: Medsi Editora Medica Cientifica Ltda, 2003.
  - Lopes, A. C., R. D. Lopes, and A. W. Liberatori Filho. “Definition of Critical Pneumonia Acquired and Therapeutic Orientation for the Community.” In Medical Practice Topics, 235–36. São Paulo, Brazil: Medsi Editora Médica e Cientifica Ltda, 2003.
  - Albers, G. W., J. E. Dalen, A. Laupacis, W. J. Manning, P. Petersen, and D. E. Singer. “Antithrombotic therapy in atrial fibrillation.,” 119:194S-206S, 2001. https://doi.org/10.1378/chest.119.1_suppl.194s.
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- Other Articles
  - Castleberry, Anthony W., Judson B. Williams, Mani A. Daneshmand, Emily Honeycutt, Linda K. Shaw, Zainab Samad, Renato D. Lopes, et al. “Response to letter regarding article, "surgical revascularization is associated with maximal survival in patients with ischemic mitral regurgitation: a 20-year experience".” Circulation, March 17, 2015. https://doi.org/10.1161/CIRCULATIONAHA.114.013125.
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- Reports
  - Al-Khatib, S. M., N. Allen LaPointe, R. Chatterjee, M. J. Crowley, M. E. Dupre, D. F. Kong, R. D. Lopes, et al. “Treatment of Atrial Fibrillation. Comparative Effectiveness Review 119.” Treatment of Atrial Fibrillation. Comparative Effectiveness Review 119. Rockville, MD: AHRQ Publication, June 28, 2013.
- Conference Papers
  - Berwanger, Otavio, Lopes Renato D. Sr, Pedro Gabriel G. De Barros e Silva, Helio P. Penna Guimaraes, Flavia C. Kojima, Viviane B. Bezerra Campos, Renato H. Nakagawa, et al. “Rivaroxaban versus Warfarin in Patients With Bioprosthetic Mitral Valves and Atrial Fibrillation or Flutter: Primary Results From the RIVER Randomized Trial.” In Circulation, 142:E486–E486, 2020.
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  - Welsh, Robert C., Renato D. Lopes, Daniel Wojdyla, Ronald Aronson, Christopher B. Granger, Stephan Windecker, Amit Vora, et al. “Prior Oral Anticoagulant Status and Outcomes in Patients With Atrial Fibrillation With an Acute Coronary Syndrome and/or Undergoing Percutaneous Coronary Intervention: Insights From the Augustus Trial.” In Circulation, Vol. 142, 2020.
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  - Harskamp, R., R. D. Lopes, Z. Li, D. Wojdyla, S. G. Goodman, R. Aronson, S. Windecker, et al. “Safety and efficacy of antithrombotic therapy according to stroke and bleeding risk in patients with atrial fibrillation and acute coronary syndrome or PCI: insights from AUGUSTUS.” In European Heart Journal, 41:645–645, 2020.
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  - McIntyre, W. F., J. Wang, S. J. Connolly, I. C. Van Gelder, R. D. Lopes, M. R. Gold, S. H. Hohnloser, et al. “Incidence and risk of short episodes of atrial fibrillation detected with 14 days of continuous electrocardiographic monitoring.” In European Heart Journal, 41:495–495, 2020.
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  - Pokorney, S., S. Garonzik, G. M. Chertow, J. B. Washam, K. Mussina, N. Bansal, C. Gadegbeku, et al. “Pharmacokinetics of apixaban in patients with end stage renal disease on hemodialysis and atrial fibrillation: results from the RENAL-AF trial.” In European Heart Journal, 41:3373–3373, 2020.
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  - Ramos, JV Santos Pereira, L Fonteles Ritt, E Sahade Darze, M. A. Viana, M. G. Oliveira, Q Borges De Oliveira, A Marlins De Oliveira, E Lima Freitas, and R Delacio Lopes. “Combination of fondaparinux with radial access is associated with low rates of in-hospital MACE and major bleeding events in patients with acute coronary syndrome.” In European Heart Journal, 41:1426–1426, 2020.
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  - Storey, R., J. H. Alexander, D. M. Wojdyla, R. Mehran, A. N. Vora, S. G. Goodman, R. Aronson, S. Windecker, C. B. Granger, and R. D. Lopes. “Choice of P2Y12 inhibitor and clinical outcomes in the AUGUSTUS study: support for an individualised approach.” In European Heart Journal, 41:1450–1450, 2020.
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  - Lopes, Renato D., Daniel Wojdyla, Christopher B. Granger, Shaun G. Goodman, Ronald Aronson, Stephan Windecker, Roxana Mehran, and John H. Alexander. “Stent Thrombosis After Percutaneous Coronary Intervention Among Patients With Atrial Fibrillation Treated With Apixaban or Aspirin: Insights From the AUGUSTUS Trial.” In Circulation, 140:E986–E986. LIPPINCOTT WILLIAMS & WILKINS, 2019.
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  - Pokorney, Sean D., Glenn M. Chertow, Hussein Al-Khalidi, Dianne Gallup, Pat Dignacco, Kurt Mussina, Nisha Bansal, et al. “Apixaban versus Warfarin for Stroke Prevention in Patients With End Stage Renal Disease on Hemodialysis and Atrial Fibrillation: Results of a Randomized Clinical Trial Assessing Safety.” In Circulation, 140:E988–89. LIPPINCOTT WILLIAMS & WILKINS, 2019.
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  - Jawitz, Oliver K., Amanda S. Stebbins, Vignesh Raman, John H. Alexander, Rajendra Mehta, Mark Stafford-Smith, and Renato D. Lopes. “Postoperative Acute Kidney Injury is Common and Associated With Increased Mortality in Patients Undergoing Cardiac Surgery: Insights From the LEVO-CTS Trial.” In Circulation, Vol. 140, 2019.
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  - Melloni, Chiara, Karen P. Alexander, Angie Wu, W Schuyler Jones, Rajendra H. Mehta, Robert W. Harrison, David Kong, et al. “Type 2 Myocardial Infarction: Incidence, Risk Factors, and Outcomes Among 41,581 Patients Enrolled in 3 Large Randomized Clinical Trials.” In Circulation, Vol. 140, 2019.
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  - Errigo, D., A. Saglietto, F. Angelini, G. Y. H. Lip, R. D. Lopes, F. Conrotto, P. G. Omede, et al. “Triple vs. double antithrombotic therapy in patients needing oral anticoagulation undergoing percutaneous coronary intervention: a meta-analysis.” In European Heart Journal, 40:1514–1514. OXFORD UNIV PRESS, 2019.
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  - Harskamp, R. E., W. A. M. Lucassen, R. D. Lopes, and H. C. Van Weert. “Risk of stroke in hypertensive patients with atrial fibrillation treated with oral anticoagulants.” In European Heart Journal, 40:3709–3709. OXFORD UNIV PRESS, 2019.
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  - Hijazi, Z., C. B. Granger, S. H. Hohnloser, J. Westerbergh, J. Lindback, J. H. Alexander, M. Keltai, et al. “Impact of different estimates of renal function on cardiovascular mortality and major bleeding in patients with atrial fibrillation on oral anticoagulation.” In European Heart Journal, 40:2951–2951. OXFORD UNIV PRESS, 2019.
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  - Rasmussen, P. V., M. L. Hansen, G. Gislason, J. Pallisgaard, M. Ruwald, C. B. Granger, R. D. Lopes, K. P. Alexander, S. M. Al-Khatib, and F. Dalgaard. “Older patients with atrial fibrillation and comorbidities are less likely to be treated with oral anticoagulation: insights from a nationwide study.” In European Heart Journal, 40:2978–2978. OXFORD UNIV PRESS, 2019.
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  - Roe, M. T., M. Szarek, Q. H. Li, D. L. Bhatt, V. Bittner, S. G. Goodman, R. A. Harrington, et al. “Efficacy of alirocumab treatment after acute coronary syndrome according to new ACC/AHA guidelines for lipid-lowering therapy.” In European Heart Journal, 40:2474–2474. OXFORD UNIV PRESS, 2019.
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  - Zeitouni, M., A. Giczewska, R. D. Lopes, D. Wojdyla, C. Christersson, R. De Caterina, P. G. Steg, C. B. Granger, L. Wallentin, and J. H. Alexander. “Apixaban 2.5 mg twice daily is effective and safe for patients with atrial fibrillation and combinations of advanced age, low body weight, and elevated creatinine: insights from ARISTOTLE.” In European Heart Journal, 40:2956–2956. OXFORD UNIV PRESS, 2019.
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  - Lopes, R. D., S. Berger, M. DiFusco, A. Kang, C. Russ, A. Afriyie, A. Earley, and L. Mantovani. “PCV97 ECONOMIC VALUE OF NON-VKA ORAL ANTICOAGULANTS (NOAC) IN NON-VALVULAR ATRIAL FIBRILLATION (NVAF): A LITERATURE REVIEW OF GLOBAL HEALTH TECHNOLOGY ASSESSMENTS (HTA).” In Value in Health, 22:S136–S136. Elsevier BV, 2019. https://doi.org/10.1016/j.jval.2019.04.532.
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  - Berwanger, Otavio, M. J. Machline-Carrion, Rafael M. Soares, Juliana Y. Santos, Bruna D. Sampaio, Lucas P. Damiani, Viviane Campos, et al. “Effects of a Multifaceted Intervention to Narrow the Evidence-Based Gap in the Treatment of High Cardiovascular Risk Patients: The BRIDGE CV Prevention Cluster Randomized Trial.” In Circulation, 138:E756–57. LIPPINCOTT WILLIAMS & WILKINS, 2018.
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  - Machline Carrion, M. J., Eliana V. Santucci, Lucas P. Damiani, Maria Cecilia Bahit, German Malaga, Octavio M. Pontes-Neto, Sheila Cristina O. Martins, et al. “An International Cluster Randomized Quality-Improvement Trial to Increase the Adherence to Evidence-Based Therapies for Acute Ischemic Stroke and Transient Ischemic Attack Patients - The Bridge Stroke Trial.” In Circulation, 138:E757–E757. LIPPINCOTT WILLIAMS & WILKINS, 2018.
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  - Al-Khatib, Sana M., Hillary Mulder, Daniel M. Wojdyla, Renato D. Lopes, Claes Held, John H. Alexander, Raffaele De Caterina, et al. “Nsaid Use is Associated With Worse Outcomes but Similar Benefits of Apixaban Over Warfarin in Patients With Atrial Fibrillation: Results From the ARISTOTLE Trial.” In Circulation, Vol. 138, 2018.
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  - Pol, Tymon, Ziad Hijazi, Johan Lindback, John H. Alexander, M Cecilia Bahit, Raffaele De Caterina, John W. Eikelboom, et al. “GDF-15 is Associated With Major Bleeding and Death Independent of Geographic Regions in Patients With Atrial Fibrillation.” In Circulation, Vol. 138, 2018.
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  - Aulin, J., Z. Hijazi, J. Lindback, J. H. Alexander, B. Gersh, C. B. Granger, M. Hanna, et al. “Elevated biomarkers are associated with increased risk of death and heart failure hospitalization in patients with atrial fibrillation: insights from the ARISTOTLE trial.” In European Heart Journal, 39:196–196. OXFORD UNIV PRESS, 2018.
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  - Rosjo, H. R., Z. Hijazi, T. Omland, J. Westerbergh, M. N. Lyngbakken, J. H. Alexander, B. J. Gersh, et al. “Cardiac troponin T concentrations are lower in women than men with atrial fibrillation but have similar prognostic value regardless of sex - insights from the ARISTOTLE trial.” In European Heart Journal, 39:897–897. OXFORD UNIV PRESS, 2018.
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  - Sharma, A., Y. Zheng, J. A. Ezekowitz, C. M. Westerhout, S. G. Goodman, P. W. Armstrong, J. B. Buse, et al. “Cluster analysis of cardiovascular risk phenotypes in patients with type 2 diabetes and established atherosclerotic cardiovascular disease: a potential approach to precision medicine.” In European Heart Journal, 39:871–871. OXFORD UNIV PRESS, 2018.
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  - Siegbahn, A., Z. Hijazi, J. Lindback, J. Oldgren, T. Pol, J. H. Alexander, R. D. Lopes, C. B. Granger, and L. Wallentin. “Novel prognostic biomarkers identified by proximity extension assay are associated with major bleeding in patients with atrial fibrillation on oral anticoagulation: insights from the ARISTOTLE trial.” In European Heart Journal, 39:1007–1007. OXFORD UNIV PRESS, 2018.
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  - Vinereanu, D., D. M. Wojdyla, J. H. Alexander, R. D. Lopes, B. J. Gersh, S. M. Al-Khatib, Z. Hijazi, A. Siegbahn, L. Wallentin, and C. B. Granger. “Faster heart rate is associated with significantly higher risk of death and hospitalization due to heart failure in patients with persistent or permanent atrial fibrillation: insights from ARISTOTLE.” In European Heart Journal, 39:1231–1231. OXFORD UNIV PRESS, 2018.
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  - BETHEL, M A. N. G. E. L. Y. N., ROBERT J. MENTZ, P. E. T. E. R. MERRILL, JOHN B. BUSE, JULIANA C. CHAN, SHAUN G. GOODMAN, N. A. Y. Y. A. R. IQBAL, et al. “Renal Outcomes in the EXenatide Study of Cardiovascular Event Lowering (EXSCEL).” In Diabetes, 67:522-P. American Diabetes Association, 2018. https://doi.org/10.2337/db18-522-p.
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  - Leonardi, Sergio, Renato D. Lopes, Ph Gabriel Steg, Freddy Abnousi, Alberto Menozzi, Jayne Prats, Stacey Mangum, et al. “Implications of different criteria for percutaneous coronary intervention-related myocardial infarction on study results of three large phase III clinical trials: The CHAMPION experience.” In Eur Heart J Acute Cardiovasc Care, 7:158–65, 2018. https://doi.org/10.1177/2048872616661692.
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  - Melloni, Chiara, Allison Dunning, Christopher B. Granger, Laine Thomas, Michel G. Khouri, David A. Garcia, Elaine M. Hylek, et al. “Efficacy and Safety of Apixaban Versus Warfarin in Patients with Atrial Fibrillation and a History of Cancer: Insights from the ARISTOTLE Trial.” In Am J Med, 130:1440-1448.e1, 2017. https://doi.org/10.1016/j.amjmed.2017.06.026.
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  - Luo, Nancy, Haolin Xu, Hani Jneid, Gregg C. Fonarow, Renato D. Lopes, Christopher B. Granger, Anne B. Curtis, et al. “High Use of Oral Anticoagulation in Eligible Patients Discharged With Heart Failure and Atrial Fibrillation Irrespective of Ejection Fraction: Insights From the AHA Get With The Guidelines- Atrial Fibrillation Program.” In Circulation, Vol. 136. LIPPINCOTT WILLIAMS & WILKINS, 2017.
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  - Wang, Alice, Babatunde Yerokun, Zhuokai Li, Andrzej Kosinski, Morgan L. Cox, Brian C. Gulack, Matthew W. Sherwood, et al. “Fragmented Care Following Transcatheter Aortic Valve Replacement is Associated With Increased 1-year Mortality and Readmission.” In Circulation, Vol. 136. LIPPINCOTT WILLIAMS & WILKINS, 2017.
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  - Aulin, J., Z. Hijazi, U. Andersson, J. H. Alexander, B. Gersh, C. B. Granger, M. Hanna, et al. “Serial IL-6 levels and risk of death in anticoagulated patients with atrial fibrillation: Insights from the ARISTOTLE trial.” In European Heart Journal, 38:780–780. OXFORD UNIV PRESS, 2017.
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  - Berger, J., G. Heizer, I. Baumgartner, F. G. R. Fowkes, P. Held, B. G. Katona, L. Norgren, et al. “Ticagrelor in patients with symptomatic peripheral artery disease and prior coronary artery disease.” In European Heart Journal, 38:452–452. OXFORD UNIV PRESS, 2017.
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  - Guimaraes, P Oliveira, R. D. Lopes, J. H. Alexander, L. Thomas, A. S. Hellkamp, L. Wallentin, E. M. Hylek, et al. “INR prior to bleeding is below 3.0 most of the time in patients with atrial fibrillation using warfarin.” In European Heart Journal, 38:576–576. OXFORD UNIV PRESS, 2017.
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  - Hijazi, Z., J. Oldgren, J. Lindback, J. H. Alexander, S. J. Connolly, J. W. Eikelboom, M. D. Ezekowitz, et al. “A novel biomarker-based risk score to predict death in patients with atrial fibrillation: Insights from the ARISTOTLE and RE-LY trials.” In European Heart Journal, 38:1221–1221. OXFORD UNIV PRESS, 2017.
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  - Pol, T., Z. Hijazi, J. H. Alexander, M. Alings, C. Erol, C. B. Granger, S. Goto, et al. “Low apolipoprotein a1 is significantly associated with decreased risk of cardiovascular events in anticoagulated patients with atrial fibrillation: insights from the ARISTOTLE trial.” In European Heart Journal, 38:760–61. OXFORD UNIV PRESS, 2017.
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  - Vinereanu, D., R. D. Lopes, H. Mulder, B. J. Gersh, M. Hanna, P. G. M. De Barros E Silva, D. Atar, L. Wallentin, C. B. Granger, and J. H. Alexander. “Clinical outcomes in patients with atrial fibrillation and echocardiographic risk factors for stroke anticoagulated with apixaban or warfarin.” In European Heart Journal, 38:776–776. OXFORD UNIV PRESS, 2017.
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  - Lehman, E Philip, Patricia Cowper, Tiffany Randolph, Andrzej Kosinski, Ranato D. Lopes, and Pamela Douglas. “UNIVERSAL USE OF CONTRAST TO DETECT LEFT VENTRICULAR THROMBUS IN PATIENTS WITH REDUCED EJECTION FRACTION IS NOT ASSOCIATED WITH IMPROVED CLINICAL OR COST-EFFECTIVENESS OUTCOMES.” In Journal of the American College of Cardiology, 69:1639–1639. ELSEVIER SCIENCE INC, 2017.
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  - Boonyawat, Kochawan, Francois Caron, Ang Li, Chatree Chai-Adisaksopha, Wendy Lim, Iorio Alfonso, Renato Delascio Lopes, David A. Garcia, and Mark Crowther. “Association of BW with Thromboembolic and Bleeding Outcomes in Phase III Randomized Controlled Trials of Direct Oral Anticoagulants: Systematic Review and Meta-Analysis.” In Blood, 128:88–88. American Society of Hematology, 2016. https://doi.org/10.1182/blood.v128.22.88.88.
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  - Hijazi, Ziad, Abhinav Sharma, Ulrika Andersson, John H. Alexander, Sana M. Al-Khatib, Michael Hanna, Claes Held, et al. “Biomarkers Predict Cause of Death More Accurately Than Clinical Variables in Patients With Atrial Fibrillation on Oral Anticoagulation Results From the ARISTOTLE Trial.” In Circulation, Vol. 134. LIPPINCOTT WILLIAMS & WILKINS, 2016.
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  - Rao, P., J. H. Alexander, D. Wojdyla, D. Atar, E. M. Hylek, M. Hanna, A. Parkhomenko, et al. “Patients with atrial fibrillation and history of falls are at high risk for bleeding but have less bleeding with apixaban than warfarin: results from the ARISTOTLE trial.” In European Heart Journal, 37:233–34. OXFORD UNIV PRESS, 2016.
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  - Harskamp, Ralf E., Niels Hoedemaker, L Kristin Newby, Pier Woudstra, Maik J. Grundeken, Marcel A. Beijk, Jan J. Piek, Jan G. Tijssen, Rajendra H. Mehta, and Robbert J. de Winter. “Procedural and clinical outcomes after use of the glycoprotein IIb/IIIa inhibitor abciximab for saphenous vein graft interventions.” In Cardiovasc Revasc Med, 17:19–23, 2016. https://doi.org/10.1016/j.carrev.2015.09.005.
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  - Zimerman, Andre, Amanda L. Stebbins, Renato D. Lopes, Patricia O. Guimaraes, Stefan K. James, John H. Alexander, Pierluigi Tricoci, et al. “Adverse Event Reporting in > 48,000 Participants in Four Acute Coronary Syndrome Trials.” In Circulation, Vol. 132. LIPPINCOTT WILLIAMS & WILKINS, 2015.
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  - Avezum, Alvaro, Renato D. Lopes, Phillip J. Schulte, Fernando Lanas, Bernard J. Gersh, Michael Hanna, Prem Pais, et al. “Apixaban in Comparison With Warfarin in Patients With Atrial Fibrillation and Valvular Heart Disease: Findings From the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) Trial.” In Circulation, 132:624–32, 2015. https://doi.org/10.1161/CIRCULATIONAHA.114.014807.
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  - Alexander, J., U. Andersson, R. D. Lopes, Z. Hijazi, S. H. Hohnloser, J. Ezekowitz, S. Halvorsen, M. Hanna, C. B. Granger, and L. Wallentin. “Stroke and bleeding outcomes with apixaban versus warfarin in patients with high creatinine, low body weight or high age receiving standard dose apixaban for stroke prevention in atrial fibrillation.” In European Heart Journal, 36:345–345. OXFORD UNIV PRESS, 2015.
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  - Bahit, M. C., R. D. Lopes, D. M. Wojdyla, C. Held, M. Hanna, D. Vinereanu, S. Goto, J. H. Alexander, L. Wallentin, and C. B. Granger. “Less non-major bleeding with apixaban versus warfarin among patients with atrial fibrillation: insights from the ARISTOTLE trial.” In European Heart Journal, 36:338–39. OXFORD UNIV PRESS, 2015.
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  - Hagstrom, E., D. Wojdyla, M. L. Neely, S. R. Stevens, R. A. Harrington, L. Wallentin, J. H. Alexander, S. G. Goodman, and R. D. Lopes. “Management and clinical consequences of major bleeding in high-risk patients following an acute coronary syndrome. Is aspirin the problem? Insights from the APPRAISE-2 trial.” In European Heart Journal, 36:861–62. OXFORD UNIV PRESS, 2015.
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  - Hijazi, Z., S. H. Hohnloser, U. Andersson, J. H. Alexander, C. B. Granger, M. Hanna, R. D. Lopes, A. Siegbahn, and L. Wallentin. “Efficacy and safety of apixaban compared with warfarin in relation to renal function over time in patients with atrial fibrillation: Insights from the ARISTOTLE trial.” In European Heart Journal, 36:339–339. OXFORD UNIV PRESS, 2015.
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  - Rordorf, R., G. M. De Ferrari, D. Wojdyla, R. De Caterina, L. Thomas, C. B. Granger, S. Leonardi, J. H. Alexander, L. Wallentin, and R. D. Lopes. “Digoxin use is associated with higher mortality among patients with atrial fibrillation with and without heart failure: insights from the ARISTOTLE trial.” In European Heart Journal, 36:1068–1068. OXFORD UNIV PRESS, 2015.
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  - Durheim, M. T., D. D. Cyr, S. M. Al-Khatib, L. E. Thomas, R. D. Lopes, B. J. Gersh, S. M. Palmer, and C. B. Granger. “Chronic Obstructive Pulmonary Disease Is Associated With Increased Risk Of Mortality Among Patients With Atrial Fibrillation: Insights From The Aristotle Trial.” In American Journal of Respiratory and Critical Care Medicine, Vol. 191. AMER THORACIC SOC, 2015.
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  - Williams, Judson B., Eric D. Peterson, Daniel Wojdyla, Ralf Harskamp, Kevin W. Southerland, T Bruce Ferguson, Peter K. Smith, Carmelo A. Milano, and Renato D. Lopes. “Central venous pressure after coronary artery bypass surgery: does it predict postoperative mortality or renal failure?” In J Crit Care, 29:1006–10, 2014. https://doi.org/10.1016/j.jcrc.2014.05.027.
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  - Cowper, Patricia A., Shubin Sheng, Kevin J. Anstrom, Judith A. Stafford, Renato D. Lopes, Linda Davidson-Ray, Lars Wallentin, et al. “The Cost-Effectiveness of Apixaban versus Warfarin in Patients With Atrial Fibrillation: Insights From the ARISTOTLE Study Group.” In Circulation, Vol. 130. LIPPINCOTT WILLIAMS & WILKINS, 2014.
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  - Englum, Brian R., Philip J. Schulte, Brian C. Gulack, C. M. Gibson, Renato D. Lopes, Michael J. Mack, T. B. Ferguson, Robert A. Harrigton, Peter K. Smith, and John H. Alexander. “The Use of Coronary Artery Bypass Grafts in Non-significant Lesions: Is There Harm to Patients?” In Circulation, Vol. 130. LIPPINCOTT WILLIAMS & WILKINS, 2014.
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  - Hijazi, Ziad, Agneta Siegbahn, Ulrike Andersson, Bertil Lindahl, Christopher B. Granger, John H. Alexander, Dan Atar, et al. “Does Repeat Measurement of High Sensitivity Troponin I Improve Prediction of Cardiovascular Events in Atrial Fibrillation?” In Circulation, Vol. 130. LIPPINCOTT WILLIAMS & WILKINS, 2014.
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  - Wallentin, Lars, Ziad Hijazi, Ulrike Andersson, Bertil Lindahl, Christopher B. Granger, John H. Alexander, Dan Atar, et al. “Single Measurement of GDF-15 Provides Reliable Prognostication of Stroke and Major Bleeding in Atrial Fibrillation.” In Circulation, Vol. 130. LIPPINCOTT WILLIAMS & WILKINS, 2014.
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  - Asberg, S., Z. Hijazi, A. Siegbahn, U. Andersson, C. B. Granger, M. Hanna, J. D. Horowitz, R. D. Lopes, B. Lindahl, and L. Wallentin. “Galectin-3 is associated with worse clinical outcome in patients with atrial fibrillation: A substudy from the ARISTOTLE trial.” In European Heart Journal, 35:426–426. OXFORD UNIV PRESS, 2014.
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  - Aulin, J., Z. Hijazi, U. Andersson, B. J. Gersh, M. Hanna, J. D. Horowitz, E. M. Hylek, R. D. Lopes, A. Siegbahn, and L. Wallentin. “Interleukin-6 and C-reactive protein and risk for cardiovascular events and death in anticoagulated patients with atrial fibrillation.” In European Heart Journal, 35:1115–16. OXFORD UNIV PRESS, 2014.
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  - Brito, FSB De Souza, A. A. Akerblom, D. W. Wojdyla, P. G. S. Steg, L. W. Wallentin, S. K. J. James, H. A. K. Katus, A. H. Himmelmann, R. C. B. Becker, and R. D. L. Lopes. “Efficacy and safety of ticagrelor in patients with acute coronary syndrome and heart failure - insights from the platelet inhibition and patient outcomes (PLATO) trial.” In European Heart Journal, 35:202–3. OXFORD UNIV PRESS, 2014.
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  - Christersson, C., L. Wallentin, U. Andersson, E. M. Hylek, S. Husted, R. De Caterina, M. Hanna, R. D. Lopes, C. B. Granger, and A. Siegbahn. “The efficacy of apixaban compared to warfarin in patients with atrial fibrillation with high coagulation activity despite anticoagulant treatment.” In European Heart Journal, 35:866–67. OXFORD UNIV PRESS, 2014.
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  - Harskamp, R. E., J. H. Alexander, R. Hager, B. Englum, P. J. Schulte, E. D. Peterson, C. M. Gibson, R. M. Califf, T. B. Ferguson, and R. D. Lopes. “Predictors of and clinical outcomes after internal mammary artery graft failure: insights from the PREVENT-IV trial.” In European Heart Journal, 35:1052–53. OXFORD UNIV PRESS, 2014.
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  - Hijazi, Z., J. Lindback, A. Siegbahn, J. H. Alexander, C. Held, M. Hanna, R. D. Lopes, J. Oldgren, C. B. Granger, and L. Wallentin. “A new biomarker based risk score for predicting major bleeding in atrial fibrillation - the ABC (age, biomarkers, current disease) risk score.” In European Heart Journal, 35:357–357. OXFORD UNIV PRESS, 2014.
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  - Hijazi, Ziad, Lars Wallentin, Agneta Siegbahn, Ulrika Andersson, John H. Alexander, Dan Atar, Bernard J. Gersh, et al. “High-sensitivity troponin T and risk stratification in patients with atrial fibrillation during treatment with apixaban or warfarin.” In J Am Coll Cardiol, 63:52–61, 2014. https://doi.org/10.1016/j.jacc.2013.07.093.
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  - Harskamp, Ralf E., John H. Alexander, Phillip J. Schulte, Colleen M. Brophy, Michael I. Mack, Eric D. Peterson, Judson B. Williams, et al. “Preservation Solutions, Patency, and Outcomes After Coronary Bypass Surgery.” In Circulation, Vol. 128. LIPPINCOTT WILLIAMS & WILKINS, 2013.
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  - Hijazi, Ziad, Agneta Siegbahn, Ulrika Andersson, Christopher B. Granger, John H. Alexander, Dan Atar, Bernard I. Gersh, et al. “Combining High Sensitivity Troponin I and T Measurements Improves Prediction of Long-Term Clinical Outcomes in Patients With Atrial Fibrillation - An Aristotle Substudy.” In Circulation, Vol. 128. LIPPINCOTT WILLIAMS & WILKINS, 2013.
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  - Lopes, Renato D., Benjamin Neely, E. M. Ohman, Diego Ardissino, Christian Hamm, Shaun G. Goodman, Deepak L. Rhatt, et al. “Timing, Profile, and Predictors of Spontaneous Myocardial Infarction Following a Non-ST-Segment Elevation Acute Coronary Syndrome Event: Insights From the TRILOGY-ACS Trial.” In Circulation, Vol. 128. LIPPINCOTT WILLIAMS & WILKINS, 2013.
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  - Lopes, Renato D., DaJuanicia N. Holmes, Laine Thomas, Jack Ansell, Gregg C. Fonarow, Bernard J. Gersh, Alan S. Go, et al. “Triple Versus Dual Antithrombotic Therapy in Patients With Atrial Fibrillation and History of Coronary Artery Disease: Insights From the ORBIT-AF Registry.” In Circulation, Vol. 128. LIPPINCOTT WILLIAMS & WILKINS, 2013.
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  - Pereira, Sabrina B., Renato D. Lopes, Maria Julia Carrion, Eliana V. Santucci, Rafael M. Soares, Matheus O. Abreu, Ligia N. Laranjeira, et al. “Early Termination of Cardiovascular Clinical Trials Registered in ClinicalTrials.gov: Where Do We Stand?” In Circulation, Vol. 128. LIPPINCOTT WILLIAMS & WILKINS, 2013.
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  - Vinereanu, Dragos, Susanna R. Stevens, John H. Alexander, Sana M. Al-Khatib, Alvaro Avezum, Cecilia Bahit, Christopher B. Granger, et al. “Efficacy and Safety of Apixaban in Patients With Atrial Fibrillation According to Sex: Results From the ARISTOTLE Trial.” In Circulation, Vol. 128. LIPPINCOTT WILLIAMS & WILKINS, 2013.
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  - Harskamp, R. E., J. M. Brennan, J. G. Gaca, M. E. Halkos, E. D. Peterson, S. V. Rao, J. B. Williams, R. J. De Winter, J. H. Alexander, and R. D. Lopes. “A systematic review of outcomes related to hybrid coronary revascularization in patients with multi-vessel coronary artery disease in the drug-eluting stent era.” In European Heart Journal, 34:834–834. OXFORD UNIV PRESS, 2013.
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  - Held, C., E. B. Hylek, J. H. Alexander, M. Hanna, R. D. Lopes, D. Wojdyla, C. B. Granger, and L. Wallentin. “Risk of events in the 30 days following a major bleed with Apixaban or Warfarin - experiences from the ARISTOTLE trial.” In European Heart Journal, 34:99–99. OXFORD UNIV PRESS, 2013.
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  - Hess, C. N., J. H. Alexander, M. L. Neely, S. James, D. Liaw, J. Amerena, A. Parkhomenko, R. A. Harrington, and R. D. Lopes. “International variation in management and outcomes in high-risk patients following acute coronary syndromes: results from the APPRAISE-2 trial.” In European Heart Journal, 34:885–885. OXFORD UNIV PRESS, 2013.
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  - Lopes, R. D., D. A. Garcia, D. Wojdyla, P. Dorian, J. H. Alexander, L. Wallentin, F. Lanas, M. Hanna, C. Held, and C. B. Granger. “Use of apixaban and warfarin in patients undergoing invasive procedures: insights from ARISTOTLE.” In European Heart Journal, 34:98–99. OXFORD UNIV PRESS, 2013.
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  - Lopes, Renato D., Alvaro Albrecht, Judson Williams, Shuang Li, T. Ferguson, Renato Kalil, Adrian Hernandez, and Eric Peterson. “HOSPITAL VARIATION IN PERIOPERATIVE INSULIN USE AND GLUCOSE CONTROL IN PATIENTS UNDERGOING CORONARY ARTERY BYPASS GRAFT SURGERY.” In Journal of the American College of Cardiology, 61:E1567–E1567. Elsevier BV, 2013. https://doi.org/10.1016/s0735-1097(13)61567-3.
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  - Lopes, Renato D., Alvaro Albrecht, Judson Williams, Shuang Li, T. Ferguson, Renato Kalil, Adrian Hernandez, and Eric Peterson. “POSTOPERATIVE GLUCOSE CONTROL FOLLOWING CORONARY ARTERY BYPASS GRAFT SURGERY: PREDICTORS AND CLINICAL OUTCOMES.” In Journal of the American College of Cardiology, 61:E1601–E1601. Elsevier BV, 2013. https://doi.org/10.1016/s0735-1097(13)61601-0.
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  - Lopes, R. D. “Efficacy and safety of apixaban compared with warfarin according to age for stroke prevention in atrial fibrillation,” 2013.
  - Fonteles Ritt, Luiz Eduardo, Gilson Soares Feitosa, Antonio Carlos Carvalho, Joel Alves Pinho Filho, Cristiano Bastos Macedo, Fabio Vilas Boas, Marcus Vinicius Andrade, et al. “Heart Failure Surviving Score is an Independent Predictor of Higher Long-Term Mortality in Patients with Heart Failure Due to Chagas Disease.” In Cardiovascular Therapeutics, 30:33–33. WILEY-BLACKWELL, 2012.
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  - Fonteles Ritt, Luiz Eduardo, Gilson Soares Feitosa, Antonio Carlos Carvalho, Joel Alves Pinho Filho, Cristiano Bastos Macedo, Fabio Vilas Boas, Marcus Vinicius Andrade, et al. “Improvement in the Six-Minute Walking Test is an Independent Predictor of Better Quality of Life in Heart Failure Due to Chagas Disease.” In Cardiovascular Therapeutics, 30:37–37. WILEY-BLACKWELL, 2012.
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  - Cornel, J., S. James, R. D. Lopes, P. Mohan, M. Neely, J. Amerena, Y. Huo, J. H. Alexander, R. A. Harrington, and L. Wallentin. “Apixaban after acute coronary syndrome in patients with heart failure: insights from the APPRAISE-2 trial.” In European Heart Journal, 33:335–36. OXFORD UNIV PRESS, 2012.
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  - McMurray, J. J. V., B. Lewis, J. Ezekowitz, B. Gersh, R. D. Lopes, D. Wojdyla, P. Mohan, L. Wallentin, J. H. Alexander, and C. B. Granger. “Risk of stroke, systemic embolism or death according to heart failure and left ventricular function status in patients with atrial fibrillation: results of the ARISTOTLE trial.” In European Heart Journal, 33:519–519. OXFORD UNIV PRESS, 2012.
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  - McMurray, J. J. V., S. J. Connolly, R. Hart, G. Flaker, R. D. Lopes, J. Wang, M. Hanna, J. H. Alexander, C. B. Granger, and L. Wallentin. “Effect of apixaban on all-cause mortality in atrial fibrillation: an imputed placebo analysis.” In European Heart Journal, 33:52–52. OXFORD UNIV PRESS, 2012.
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  - Siegbahn, A., C. Christersson, M. Schollin, J. H. Alexander, J. Horowitz, E. M. Hylek, R. D. Lopes, P. Mohan, C. B. Granger, and L. Wallentin. “Increased levels of D-dimer identify patients with atrial fibrillation at high risk for bleeding an ARISTOTLE substudy.” In European Heart Journal, 33:51–51. OXFORD UNIV PRESS, 2012.
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  - Lopes, Renato D., Sana Al-Khatib, Lars Wallentin, Hongqiu Yang, Jack Ansell, J Donald Easton, Cetin Erol, et al. “EFFICACY AND SAFETY OF APIXABAN COMPARED WITH WARFARIN ACCORDING TO CHADS2 AND HASBLED RISK SCORES FOR STROKE PREVENTION IN ATRIAL FIBRILLATION.” In Journal of the American College of Cardiology, 59:E574–E574. Elsevier BV, 2012. https://doi.org/10.1016/s0735-1097(12)60575-0.
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  - Fosbøl, Emil L., Tracy Y. Wang, Jonathan Piccini, Renato D. Lopes, Bimal Shah, Karen P. Alexander, Shuang Li, Matthew T. Roe, and Eric D. Peterson. “LONG-TERM SAFETY OF ANTITHROMBOTIC THERAPY IN NON-ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION PATIENTS WITH ATRIAL FIBRILLATION.” In Journal of the American College of Cardiology, 57:E948–E948. Elsevier BV, 2011. https://doi.org/10.1016/s0735-1097(11)60948-0.
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  - Kuijt, Wichert J., Matthew T. Roe, Cindy L. Green, Karen S. Pieper, Susanna R. Stevens, Renato D. Lopes, Robert H. Christenson, et al. “PREDICTION OF DEATH AND CONGESTIVE HEART FAILURE USING MULTIPLE CONCOMITANT ANGIOGRAPHIC BIOCHEMICAL AND ELECTROCARDIOGRAPHIC BIOMARKERS IN PATIENTS WITH ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION TREATED WITH PRIMARY PERCUTANEOUS CORONARY INTERVENTION.” In Journal of the American College of Cardiology, 57:E1074–E1074. Elsevier BV, 2011. https://doi.org/10.1016/s0735-1097(11)61074-7.
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  - Truffa, Adriano A., Renato D. Lopes, Kyle R. White, Rajendra H. Mehta, Manesh R. Patel, Karen S. Pieper, Paul W. Armstrong, and Christopher B. Granger. “SERIOUS INFECTIONS IN PATIENTS WITH ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION TREATED WITH PRIMARY PCI ARE RARE, BUT ASSOCIATED WITH HIGHER MORTALITY.” In Journal of the American College of Cardiology, 57:E980–E980. Elsevier BV, 2011. https://doi.org/10.1016/s0735-1097(11)60980-7.
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  - Mehta, R., E. Honeycutt, R. D. Lopes, L. K. Shaw, and M. H. Sketch. “Acute renal failure after coronary artery bypass surgery: impact of recovery of renal function on long-term mortality.” In European Heart Journal, 31:612–612. OXFORD UNIV PRESS, 2010.
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  - Mehta, R., T. B. Ferguson, R. D. Lopes, G. E. Hafley, M. J. Mack, N. T. Kouchoukos, C. M. Gibson, R. A. Harrington, R. M. Califf, and J. H. Alexander. “Saphenous vein grafts with multiple versus single distal targets in patients undergoing coronary artery bypass surgery: one-year graft failure and five-year outcomes from the PREVENT-IV trial.” In European Heart Journal, 31:881–881. OXFORD UNIV PRESS, 2010.
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  - Chan, Mark, Jie L. Sun, Tracy Y. Wang, Renato D. Lopes, Marc E. Jolicoeur, Karen S. Pieper, Sunil V. Rao, et al. “Discharge Without Antiplatelet Therapy After Inhospital Bleeding is an Independent Predictor of 6-Month Mortality Among Patients With Acute Coronary Syndrome: A Pooled Analysis From PURSUIT, PARAGON-A, PARAGON-B and SYNERGY.” In Circulation, 120:S1144–S1144. LIPPINCOTT WILLIAMS & WILKINS, 2009.
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  - Mehta, Rajendra H., Renato D. Lopes, Amanda Stebbins, Sunil V. Rao, Karen S. Pieper, Robert M. Califf, John H. Alexander, and Christopher B. Granger. “Differences in Bleeding Rates Accounts for All of the Excess Mortality in African Americans Compared With Caucasians With ST-Elevation Myocardial Infarction treated With Fibrinolysis.” In Circulation, 120:S522–23. LIPPINCOTT WILLIAMS & WILKINS, 2009.
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  - Lopes, Renato D., Harvey D. White, Judith Hochman, John R. Horton, Frans Van de Werf, Diego Ardissino, Torsten T. Nielsen, et al. “New onset atrial fibrillation following myocardial infarction is a strong independent predictor of mortality in patients treated with primary percutaneous coronary intervention.” In Journal of the American College of Cardiology, 51:A11–12. ELSEVIER SCIENCE INC, 2008.
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