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Charles Scales Jr.

Associate Professor of Urology
Urology
DUMC 3707, Durham, NC 27710
300 W Morgan Street - 8th Floor Receptionist Desk, Duke Box 3850, Durham, NC 27701

Overview


Charles D. Scales, Jr., MD MSHS FACS is Associate Dean for Clinical Research Initiatives and Associate Professor of Urology and Population Health Science. He completed medical school and residency training in urology at Duke University.  After residency, Dr. Scales completed the Robert Wood Johnson Foundation Clinical Scholars Program at UCLA, where he received advanced training in health services research, health policy, and quality of care.  He teaches these skills to future generations through the Duke Master of Management in Clinical Informatics (MMCi) degree program, and in 2025 will present his course, “Data, Information, and Health Care Transformation” for the 10th consecutive year.

From the research perspective, Dr. Scales has a longstanding interest in the epidemiology of and patient care for urinary stone disease.  Recent studies have redefined the epidemiology of urinary stone disease in the United States, compared the effectiveness of dominant stone removal technologies, and identified new opportunities for improving patient-centered and policy-relevant outcomes, such as unplanned care after procedural interventions.  His research and perspective on urinary stone disease has been highlighted in U.S. News & World Report, Reuters, NPR, and the Wall Street Journal, among other media outlets.

Currently, Dr. Scales leads a diverse health services and clinical research program at the Duke Clinical Research Institute, where he is the Principal Investigator for the Scientific Data and Research Center for the NIDDK Urinary Stone Disease Research Network (U01).  Within the USDRN, he leads the multicenter Prevention of Urinary Stones with Hydration (PUSH) randomized clinical trial, which is the largest randomized controlled stone prevention trial to date, and the multicenter Study to Enhance Understanding of Stent-Associated Symptoms (STENTS) cohort study. 

Current Duke Appointments & Affiliations


Associate Professor of Urology · 2025 - Present Urology, Clinical Science Departments
Associate Dean for Clinical Research Initiatives · 2024 - Present School of Medicine
Vice Chair of Research · 2025 - Present Urology, Clinical Science Departments
Associate Professor in Population Health Sciences · 2021 - Present Population Health Sciences, Basic Science Departments
Membership in the Duke Clinical Research Institute · 2013 - Present Duke Clinical Research Institute, Institutes and Centers
Affiliate Faculty Member, Duke-Margolis Institute for Health Policy · 2024 - Present Duke-Margolis Institute for Health Policy, University Institutes and Centers

Recent News Items


Published April 9, 2026
Drinking Enough Water to Prevent Kidney Stones is Difficult, Even With Support
Published March 17, 2020
US News & World Report
Types of Kidney Stone Surgery
Published October 31, 2019
UroToday
WCE2019: Quality of Life in Stone Formers

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Recent Scholarly Works


The Third Endourological Society Census Report.

Journal article J Endourol · July 2026 INTRODUCTION: To help understand and better meet the needs of its membership, the Endourological Society (ES) conducts an annual membership survey. The purpose of this article is to report the findings of the third annual census of the ES. MATERIALS AND ME ... Full text Link to item Cite

Chemodenervation Use for Overactive Bladder in Female Medicare Beneficiaries.

Journal article Urogynecology (Phila) · June 1, 2026 IMPORTANCE: Only a fraction of women with overactive bladder (OAB) receive effective treatment for this condition; inequities in access to OAB care must be understood. OBJECTIVE: The objective of this study was to explore features associated with intradet ... Full text Link to item Cite
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Recent Grants


1/3 CTSA UM1 at Duke University

ResearchCore Leader · Awarded by National Institutes of Health · 2025 - 2032

2/3 CTSA K12 Program at Duke University

ResearchMentor · Awarded by National Center for Advancing Translational Sciences · 2025 - 2030

UrogynCREST Program

ResearchMentor · Awarded by Eunice Kennedy Shriver National Institute of Child Health and Human Development · 2019 - 2029

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Education


Duke University, School of Medicine · 2004 M.D.