Scholars@Duke
Charles Douglas Scales Jr.

Charles Douglas Scales Jr.

Associate Professor of Urology
Urology
chuck.scales@duke.edu
DUMC 3707, Durham, NC 27710
300 W Morgan Street - 8th Floor Receptionist Desk, Duke Box 3850, Durham, NC 27701

Selected Publications

Development of Prediction Models for Severe Pain and Urinary Symptoms After Ureteroscopy With Ureteral Stent Placement: Results From the STENTS Study and Initial Validation of Pain Interference.

Journal Article J Urol · April 2025 PURPOSE: We developed prediction models for severe pain and urinary symptoms after ureteroscopy with ureteral stent placement. MATERIALS AND METHODS: The development cohort included 424 adults and adolescents enrolled in the multicenter STENTS prospective ... Full text Link to item Cite

Reply by Authors.

Journal Article J Urol · April 2025 Full text Link to item Cite

Risk Stratification for Sentinel Lymph Node Positivity in Older Women With Early-Stage Estrogen Receptor-Positive/Human Epidermal Growth Factor Receptor 2 Neu-Negative Invasive Breast Cancer.

Journal Article JCO Clin Cancer Inform · March 2025 PURPOSE: Guidelines recommend omission of sentinel lymph node biopsy (SLNB) for axillary staging in select patients age 70 years and older with early-stage estrogen receptor-positive (ER+), human epidermal growth factor receptor 2 neu-negative (HER2-) inva ... Full text Link to item Cite

Infection Risk in Patients with Mixed Flora in Urine Cultures Prior to Ureteroscopy.

Journal Article J Endourol · February 10, 2025 Purpose: Urine cultures are routinely used to inform preoperative antibiotic choice and duration prior to endourologic surgery. The presence of mixed flora in preoperative urine cultures holds unclear clinical significance. This study examines infectious o ... Full text Link to item Cite

A Patient-Prioritized Research Agenda for Clinical Trials in Kidney Stone Disease.

Journal Article J Urol · January 2025 PURPOSE: To ensure that research on kidney stones provides meaningful impact for the kidney stone community, patients and caregivers should be engaged as stakeholders in clinical trial design, starting at study inception. This project aimed to elicit, refi ... Full text Link to item Cite

Adjudication of Self-reported Symptomatic Stone Recurrence in the Prevention of Urinary Stones With Hydration Trial.

Journal Article Urology · December 2024 OBJECTIVE: To assess accuracy of self-reported stone events in a large clinical trial by adjudication against the weight of documentation for spontaneous stone passage or surgical intervention. METHODS: Participants in the Prevention of Urinary Stones with ... Full text Link to item Cite

The Second Endourological Society Census Report.

Journal Article J Endourol · November 2024 Introduction and Objective: As part of the Endourological Society's (ES) initiative to continuously enhance the field of endourology, the second annual census was circulated after the World Congress of Endourology and Uro-Technology 2022 (WCET22). Methods: ... Full text Link to item Cite

Frailty, Specialized Care, and Sociodemographic Factors: Disparities in Oral Pharmacotherapy Class Utilization Among Medicare Part D Beneficiaries With Overactive Bladder in the United States.

Journal Article Urology · September 2024 OBJECTIVE: To describe the prevalence of frailty among Medicare beneficiaries with overactive bladder (OAB), analyze oral therapy patterns, and examine potential disparities in treatment. METHODS: This retrospective cohort study utilized the 20% Research I ... Full text Link to item Cite

Systemic treatments for advanced prostate cancer: relationship between health insurance plan and treatment costs.

Journal Article Am J Manag Care · September 1, 2024 OBJECTIVES: The high costs of cancer care can cause significant harm to patients and society. Prostate cancer, the leading nonskin malignancy in men, is responsible for the second-highest out-of-pocket (OOP) payments among all malignancies. Multiple first- ... Full text Link to item Cite

Work absence and productivity loss of patients undergoing a trial of spontaneous passage for ureteral stones.

Journal Article Urolithiasis · August 6, 2024 Patients with ureteral stones are often managed with a spontaneous trial of passage. While cost effective, the current literature has not examined the effects of a trial of passage on patients' work productivity. In this study, we aim to characterize work ... Full text Link to item Cite

Design and Rationale of the Outcomes Database to Prospectively Assess the Changing Therapy Landscape in Renal Cell Carcinoma Registry: A Multi-institutional, Prospective Study of Patients with Metastatic Renal Cell Carcinoma.

Journal Article Eur Urol Open Sci · August 2024 INTRODUCTION AND HYPOTHESES: The Outcomes Database to prospectivelY aSSEss the changing TherapY landscape in Renal Cell Carcinoma (ODYSSEY RCC) Registry is a large, nationally representative prospective registry of patients with metastatic renal cell carci ... Full text Link to item Cite

Examining the Role of Frailty on Treatment Patterns and Complications Among Older Women Undergoing Procedure-Based Treatment for Urinary Incontinence.

Journal Article J Gerontol A Biol Sci Med Sci · June 1, 2024 BACKGROUND: Aging beyond 65 years is associated with increased prevalence of urinary incontinence (UI), frailty, and increased complication rate with UI treatments. To investigate this relationship, we examined frailty as a predictor of procedure-based UI ... Full text Link to item Cite

Using structured problem solving to promote fluid consumption in the prevention of urinary stones with hydration (PUSH) trial.

Journal Article BMC Nephrol · May 28, 2024 BACKGROUND: Structured Problem Solving (SPS) is a patient-centered approach to promoting behavior change that relies on productive collaboration between coaches and participants and reinforces participant autonomy. We aimed to describe the design, implemen ... Full text Link to item Cite

Proposing the "Continuum of UTI" for a Nuanced Approach to Diagnosis and Management of Urinary Tract Infections.

Journal Article J Urol · May 2024 PURPOSE: Patients with suspected UTIs are categorized into 3 clinical phenotypes based on current guidelines: no UTI, asymptomatic bacteriuria (ASB), or UTI. However, all patients may not fit neatly into these groups. Our objective was to characterize clin ... Full text Link to item Cite

Primary Palliative Care in Urology: Quality Improvement Summit 2021-2022.

Journal Article Urol Pract · May 2024 INTRODUCTION: The AUA convened a 2021-2022 Quality Improvement Summit to bring together interdisciplinary providers to inform the current state and to discuss potential strategies for integrating primary palliative care into urology practice. We hypothesiz ... Full text Link to item Cite

The cost of lung transplantation in the United States: How high is too high?

Journal Article JTCVS Open · April 2024 OBJECTIVES: To identify patient and process factors that contribute to the high cost of lung transplantation (LTx) in the perioperative period, which may allow transplant centers to evaluate situations in which transplantation is most cost-effective to inf ... Full text Link to item Cite

Contribution of Hypersensitivity to Postureteroscopy Ureteral Stent Pain: Findings From Study to Enhance Understanding of Stent-associated Symptoms.

Journal Article Urology · February 2024 OBJECTIVE: To examine the relationships between preoperative hypersensitivity to pain and central sensitization, and postoperative ureteral stent pain after ureteroscopy (URS) for urinary stones. METHODS: Adults enrolled in the STudy to Enhance uNderstandi ... Full text Link to item Cite

Leveraging behavioral modification technology for the prevention of kidney stones.

Journal Article Curr Opin Urol · January 1, 2024 PURPOSE OF REVIEW: The purpose of this review is to examine the use of technology to help promote and maintain behaviors that decrease stone recurrence. RECENT FINDINGS: Behavior change is a complex process with various interacting components. Recent devel ... Full text Link to item Cite

Patient education and extracorporeal membrane oxygenation preferences of patients and providers in COVID care.

Journal Article PLoS One · 2024 BACKGROUND: Extracorporeal membrane oxygenation (ECMO) represents an important but limited treatment for patients with severe COVID-19. We assessed the effects of an educational intervention on a person's ECMO care preference and examined whether patients ... Full text Link to item Cite

Discrete-Choice Experiment to Understand the Preferences of Patients with Hormone-Sensitive Prostate Cancer in the USA, Canada, and the UK.

Journal Article Patient · November 2023 BACKGROUND: Treatment options for patients with metastatic hormone-sensitive prostate cancer (mHSPC) have broadened, and treatment decisions can have a long-lasting impact on patients' quality of life. Data on patient preferences can improve therapeutic de ... Full text Link to item Cite

Rural For-Profit Hospitals Are Associated With Higher Commercial Prices for 3 Common Urological Procedures.

Journal Article Urol Pract · November 2023 INTRODUCTION: Rural patients lack access to urological services, and high local prices may dissuade underinsured patients from surgery. We sought to describe commercially insured prices for 3 urological procedures at rural vs metropolitan and for-profit vs ... Full text Link to item Cite

Incidence and cost of potentially avoidable emergency department visits for urolithiasis.

Journal Article Am J Manag Care · November 1, 2023 OBJECTIVES: Urolithiasis represents a leading cause of emergency department (ED) presentation nationally, affecting approximately 10% of Americans. However, most patients require neither hospital admission nor surgical intervention. This study investigates ... Full text Link to item Cite

Patients' Experiences With the Removal of a Ureteral Stent: Insights From In-depth Interviews With Participants in the USDRN STENTS Qualitative Cohort Study.

Journal Article Urology · August 2023 OBJECTIVE: To describe the experiences of patients undergoing stent removal in the USDRN Study to Enhance Understanding of Stent-Associated Symptoms (STENTS), a prospective, observational cohort study of patients with short-term ureteral stent placement po ... Full text Link to item Cite

EDITORIAL COMMENT.

Journal Article Urology · July 2023 Full text Link to item Cite

Pediatric renal malignancy diagnosis is associated with significant burden of care for families.

Journal Article Pediatr Blood Cancer · June 19, 2023 BACKGROUND AND OBJECTIVES: New childhood cancer diagnoses require timely, complex care coordination and cause considerable logistic burden for families. We used renal tumors as a model to examine healthcare utilization and cost following new solid tumor di ... Full text Link to item Cite

Disparities in Prostate Cancer Screening for Transgender Women: An Analysis of the MarketScan Database.

Journal Article Urology · June 2023 OBJECTIVE: To describe the prevalence of PSA screening amongst transgender women. A transgender individual is someone whose gender identity differs from their birth sex or the societal norms of that assigned sex. There are no formal guidelines regarding PS ... Full text Link to item Cite

The Patient Voice: Stent Experiences After Ureteroscopy-Insights from In-Depth Interviews with Participants in the USDRN STENTS Nested Qualitative Cohort Study.

Journal Article J Endourol · June 2023 Purpose: Ureteral stents are commonly used after ureteroscopy and cause significant discomfort, yet qualitative perspectives on patients' stent experiences remain unknown. We describe psychological, functional, and interpersonal effects of post-ureteroscop ... Full text Link to item Cite

Effects of Delayed Surgical Intervention Following Emergency Department Presentation on Stone Surgery Complexity.

Journal Article J Endourol · June 2023 Introduction and Objective: Prior literature had demonstrated increased stone burden and higher rates of staged surgery in individuals of lower socioeconomic status (SES). Low SES individuals are more likely to experience delays in definitive stone surgery ... Full text Link to item Cite

Risk Factors for Increased Stent-associated Symptoms Following Ureteroscopy for Urinary Stones: Results From STENTS.

Journal Article J Urol · May 2023 PURPOSE: The STudy to Enhance uNderstanding of sTent-associated Symptoms sought to identify risk factors for pain and urinary symptoms, as well as how these symptoms interfere with daily activities after ureteroscopy for stone treatment. MATERIALS AND METH ... Full text Link to item Cite

Complications, Costs, and Healthcare Resource Utilization After Staged, Delayed, and Immediate Free-Flap Breast Reconstruction: A Longitudinal, Claims-Based Analysis.

Journal Article Ann Surg Oncol · April 2023 BACKGROUND: There is a lack of consensus detailing the optimal approach to free-flap breast reconstruction when considering immediate, delayed, or staged techniques. This study compared costs, complications, and healthcare resource utilization (HCRU) acros ... Full text Link to item Cite

Medication Payments by Insurers and Patients for the Treatment of Metastatic Castrate-Resistant Prostate Cancer.

Journal Article JCO Oncol Pract · April 2023 PURPOSE: The implications of high prices for cancer drugs on health care costs and patients' financial burdens are a growing concern. Patients with metastatic castrate-resistant prostate cancer (mCRPC) are often candidates for multiple first-line systemic ... Full text Link to item Cite

Association of Rural Hospital for-Profit Status With Higher Publicly Reported Prices for the Components of Inpatient Hematuria Evaluation Among Commercially Insured Patients.

Journal Article Urol Pract · March 2023 INTRODUCTION: Rural patients have limited access to urological care and are vulnerable to high local prices. Little is known about price variation for urological conditions. We aimed to compare reported commercial prices for the components of inpatient hem ... Full text Link to item Cite

Surgical Evaluation in Patients Undergoing Radiation Therapy for Early-Stage Lung Cancer.

Journal Article Ann Thorac Surg · February 2023 BACKGROUND: Stereotactic body radiation therapy (SBRT) is used to treat stage I non-small cell lung cancer (NSCLC) in nonsurgical candidates, although guidelines specify that inoperability be determined in multidisciplinary fashion. We characterized NSCLC ... Full text Link to item Cite

Predictors of hospital bypass for rural residents seeking common elective surgery.

Journal Article Surgery · February 2023 BACKGROUND: Surgical bypass occurs when rural residents receive surgical care at a nonlocal hospital. Given limited knowledge of current bypass rates, we evaluated rates and predictors of bypass for common procedures. METHODS: We used 2014 to 2016 all-paye ... Full text Link to item Cite

End-of-Life Care for Patients With Metastatic Renal Cell Carcinoma in the Era of Oral Anticancer Therapy.

Journal Article JCO Oncol Pract · February 2023 PURPOSE: New therapies including oral anticancer agents (OAAs) have improved outcomes for patients with metastatic renal cell carcinoma (mRCC). However, little is known about the quality of end-of-life (EOL) care and systemic therapy use at EOL in patients ... Full text Link to item Cite

Comparison of Cost and Perioperative Outcomes Among Patients Undergoing Simple Prostatectomy and Laser Enucleation of the Prostate.

Journal Article J Endourol · January 2023 Introduction: Simple prostatectomy (SP) and laser enucleation of the prostate (LEP) are treatments for symptomatic benign prostatic hyperplasia (BPH) in men with large glands (e.g., >80 g). The decision between the two operations is often dependent on surg ... Full text Link to item Cite

Redlining has led to increasing rates of nephrolithiasis in minoritized populations: a hypothesis.

Journal Article Curr Opin Nephrol Hypertens · January 1, 2023 PURPOSE OF REVIEW: The persistent rise in kidney stone prevalence in recent decades has prompted much speculation as to the causes. There has been some discussion about the effect of heat on nephrolithiasis. Here, we review recent data and postulate that h ... Full text Link to item Cite

Disparities in healthcare utilization and outcomes for older adults with infected stones

Conference JOURNAL OF THE AMERICAN GERIATRICS SOCIETY · 2023 Cite

Evaluating the Quality of Outpatient Surgical Procedures

Conference JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS · 2023 Cite

Patient- And Provider-Level Predictors of Survival Among Patients With Metastatic Renal Cell Carcinoma Initiating Oral Anticancer Agents.

Journal Article Clin Genitourin Cancer · October 2022 PURPOSE: In an era of rapid expansion of FDA approvals for oral anticancer agents (OAAs), it is important to understand the factors associated with survival among real-world populations, which include groups not well-represented in pivotal clinical trials ... Full text Link to item Cite

Oral Anticancer Agent (OAA) Adherence and Survival in Elderly Patients With Metastatic Renal Cell Carcinoma (mRCC).

Journal Article Urology · October 2022 OBJECTIVE: To examine real-world adherence to oral anticancer agents (OAAs) and its association with outcomes among Medicare beneficiaries with metastatic renal cell carcinoma (mRCC). METHODS: SEER-Medicare retrospective cohort study of patients with metas ... Full text Link to item Cite

Adverse outcomes after minimally invasive surgery for pelvic organ prolapse in women 65 years and older in the United States.

Journal Article Int Urogynecol J · September 2022 INTRODUCTION AND HYPOTHESIS: To describe complications at the time of surgery, 90-day readmission and 1-year reoperation rates after minimally invasive pelvic organ prolapse (POP) in women > 65 years of age in the US using Medicare 5% Limited Data Set (LDS ... Full text Link to item Cite

Influence of Clinical and Sociodemographic Factors on the Management, Costs and Outcomes of Acute Urinary Retention in the Acute Care Setting.

Journal Article Urol Pract · July 2022 INTRODUCTION: We evaluated clinical and sociodemographic factors that influence care pathways following acute urinary retention with attention to subsequent bladder outlet procedures. METHODS: This was a retrospective cohort study examining patients who pr ... Full text Link to item Cite

Patient, provider, and hospital factors associated with oral anti-neoplastic agent initiation and adherence in older patients with metastatic renal cell carcinoma.

Journal Article J Geriatr Oncol · June 2022 INTRODUCTION: Oral anti-neoplastic agents (OAAs) for metastatic renal cell carcinoma (mRCC) are associated with increased cancer-specific survival. However, racial disparities in survival persist and older adults have the lowest rates of cancer-specific su ... Full text Link to item Cite

Predictors and Cost Comparison of Subsequent Urinary Stone Care at Index Versus Non-Index Hospitals.

Journal Article Urology · June 2022 ObjectiveTo examine the effects of care fragmentation, or the engagement of different health care systems along the continuum of care, on patients with urinary stone disease.MethodsAll-payer data from the 2016 Healthcare Cost and Utilizat ... Full text Cite

Predicting postoperative complications in pediatric surgery: A novel pediatric comorbidity index.

Journal Article J Pediatr Urol · June 2022 INTRODUCTION/BACKGROUND: Comorbidity-driven surgical risk assessment is essential for informed patient counseling, risk-stratification, and outcomes-based health-services research. Existing mortality-focused comorbidity indices have had mixed success at ri ... Full text Link to item Cite

Behavioral Economics in Urology: A Scoping Review.

Journal Article J Urol · June 2022 PURPOSE: Behavioral economics is the study of human behavior in the context of irrationality, self-control and self-interest. It has been leveraged in a variety of ways in health care, including efforts to decrease smoking, encourage weight loss and promot ... Full text Link to item Cite

Predicting in-hospital length of stay: a two-stage modeling approach to account for highly skewed data.

Journal Article BMC Med Inform Decis Mak · April 24, 2022 BACKGROUND: In the early stages of the COVID-19 pandemic our institution was interested in forecasting how long surgical patients receiving elective procedures would spend in the hospital. Initial examination of our models indicated that, due to the skewed ... Full text Link to item Cite

Quality of life impact and recovery after ureteroscopy and stent insertion: insights from daily surveys in STENTS.

Journal Article BMC Urol · April 6, 2022 BACKGROUND: Our objective was to describe day-to-day evolution and variations in patient-reported stent-associated symptoms (SAS) in the STudy to Enhance uNderstanding of sTent-associated Symptoms (STENTS), a prospective multicenter observational cohort st ... Full text Link to item Cite

Management of Chronic Rhinosinusitis Prior to Otolaryngology Referral: An Opportunity for Quality Improvement.

Journal Article Otolaryngol Head Neck Surg · March 2022 OBJECTIVE: The management of chronic rhinosinusitis (CRS) by a nonotolaryngologist prior to otolaryngology referral is an important component of the patient care pathway. The purpose of this study is to characterize CRS management during this period and to ... Full text Link to item Cite

Factors associated with the quality of end-of-life care for patients with metastatic renal cell carcinoma.

Conference Journal of Clinical Oncology · February 20, 2022 300 Background: Although oral anti-cancer agents (OAAs) have improved outcomes for patients with metastatic renal cell carcinoma (mRCC), most patients still die from the disease. High quality end-of-life (EOL) care remains a cruc ... Full text Cite

Postoperative changes in cognition and cerebrospinal fluid neurodegenerative disease biomarkers.

Journal Article Ann Clin Transl Neurol · February 2022 OBJECTIVE: Numerous investigators have theorized that postoperative changes in Alzheimer's disease neuropathology may underlie postoperative neurocognitive disorders. Thus, we determined the relationship between postoperative changes in cognition and cereb ... Full text Open Access Link to item Cite

Geographic Variations in Healthcare Utilization and Expenditure for Chronic Rhinosinusitis: A Population-Based Approach.

Journal Article Laryngoscope · December 2021 OBJECTIVES/HYPOTHESIS: Chronic rhinosinusitis (CRS) is a common and costly health problem in the United States. A better understanding of healthcare resource utilization (HCRU) and healthcare expenditure (HCE) pertaining to CRS is required. The objective o ... Full text Link to item Cite

Patterns and Predictors of Oral Anticancer Agent Use in Diverse Patients With Metastatic Renal Cell Carcinoma.

Journal Article JCO Oncol Pract · December 2021 PURPOSE: Availability of targeted oral anticancer agents (OAAs) has transformed care for patients with metastatic renal cell carcinoma (mRCC). Our objective was to identify patterns and predictors of OAA use within 12 months after mRCC was detected to unde ... Full text Link to item Cite

Provider- and patient-level predictors of oral anticancer agent initiation and adherence in patients with metastatic renal cell carcinoma.

Journal Article Cancer Med · October 2021 BACKGROUND: Improving oral anticancer agent (OAA) initiation and adherence is the important quality-of-care issues, particularly since one fourth of anticancer agents being developed will be administered orally. Our objective was to identify provider- and ... Full text Link to item Cite

Patient- and provider-level predictors of mortality among patients with metastatic renal cell carcinoma receiving oral anticancer agents.

Conference Journal of Clinical Oncology · October 1, 2021 116 Background: It is important to understand how emerging new therapies, such as oral anti-cancer agents (OAAs), diffuse across and can improve outcomes within real-world populations, which include age groups and racial groups n ... Full text Cite

Strategies for research participant engagement: A synthetic review and conceptual framework.

Journal Article Clin Trials · August 2021 BACKGROUND: Research participant engagement, which we define as recruitment and retention in clinical trials, is a costly and challenging issue in clinical research. Research teams have leveraged a variety of strategies to increase research participant eng ... Full text Link to item Cite

Acute Care Resource Use After Elective Surgery in the United States: Implications During the COVID-19 Pandemic.

Journal Article Am J Crit Care · July 1, 2021 BACKGROUND: The COVID-19 pandemic created pressure to delay inpatient elective surgery to increase US health care capacity. This study examined the extent to which common inpatient elective operations consume acute care resources. METHODS: This cross-secti ... Full text Link to item Cite

Healthcare Resource Utilization for Chronic Rhinosinusitis in Older Adults.

Journal Article Healthcare (Basel) · June 25, 2021 OBJECTIVES: Chronic rhinosinusitis (CRS) is a common and costly health problem in the United States. While often associated with younger adults, CRS can affect the elderly. As the aging population increases in the United States, the cost burden of CRS in o ... Full text Open Access Link to item Cite

Evaluation of a Novel Single-Use Flexible Ureteroscope.

Journal Article J Endourol · June 2021 Introduction: A novel single-use flexible ureteroscope promises the optical characteristics and maneuverability of a reusable fourth-generation flexible ureteroscope. In this study, the LithoVue Single-Use Digital flexible ureteroscope was directly compare ... Full text Link to item Cite

Study to Enhance Understanding of Stent-Associated Symptoms: Rationale and Study Design.

Journal Article J Endourol · June 2021 Background: Ureteral stents are commonly employed after ureteroscopy to treat urinary stone disease, but the devices impose a substantial burden of stent-associated symptoms (SAS), including pain and urinary side effects. The NIDDK (National Institute of D ... Full text Link to item Cite

Prevention of Urinary Stones With Hydration (PUSH): Design and Rationale of a Clinical Trial.

Journal Article Am J Kidney Dis · June 2021 RATIONALE & OBJECTIVE: Although maintaining high fluid intake is an effective low-risk intervention for the secondary prevention of urinary stone disease, many patients with stones do not increase their fluid intake. STUDY DESIGN: We describe the rationale ... Full text Open Access Link to item Cite

Feasibility and efficacy of a decision aid for emergency department patients with suspected ureterolithiasis: protocol for an adaptive randomized controlled trial.

Journal Article Trials · March 10, 2021 BACKGROUND: Approximately 2 million patients present to emergency departments in the USA annually with signs and symptoms of ureterolithiasis (or renal colic, the pain from an obstructing kidney stone). Both ultrasound and CT scan can be used for diagnosis ... Full text Link to item Cite

Real-world systemic therapy utilization in Medicare patients with locally advanced or metastatic urothelial carcinoma diagnosed between 2008 and 2012.

Journal Article J Geriatr Oncol · March 2021 PURPOSE: Treatment of advanced urothelial carcinoma (UC) remains a challenging clinical entity occurring predominantly in older patients with limited treatment options. However, real-world treatment patterns, differential cancer center access, and associat ... Full text Link to item Cite

Patterns and predictors of oral anticancer agent utilization in diverse metastatic renal cell carcinoma patients.

Conference Journal of Clinical Oncology · February 20, 2021 279 Background: Availability of targeted oral anti-cancer agents (OAA) has transformed care delivery for metastatic renal cell carcinoma (RCC) patients. Our objective was to identify patterns and predictors of OAA use within the ... Full text Cite

Oral anticancer agent (OAA) adherence and survival in elderly patients with metastatic renal cell carcinoma (mRCC).

Conference Journal of Clinical Oncology · February 20, 2021 280 Background: Multiple effective oral anticancer agents (OAAs) are now approved for the treatment of patients with advanced or metastatic renal cell carcinoma (mRCC) based on improvement in overall and progression-free survival ... Full text Cite

Parental preferences for vesicoureteral reflux treatment: Profile case best-worst scaling.

Journal Article J Pediatr Urol · February 2021 INTRODUCTION: Vesicoureteral reflux is a common pediatric urologic condition that often has several reasonable treatment options depending on condition severity. In order to choose the best treatment for their child, parents are expected to make judgements ... Full text Link to item Cite

Real-World Utilization of Oral Anticancer Agents and Related Costs in Older Adults with Metastatic Renal Cell Carcinoma in the United States.

Journal Article Kidney Cancer · 2021 BACKGROUND: Substantial racial and socioeconomic disparities in metastatic RCC (mRCC) have persisted following the introduction of targeted oral anticancer agents (OAAs). The relationship between patient characteristics and OAA access and costs that may un ... Full text Link to item Cite

Alpha-blockers after shock wave lithotripsy for renal or ureteral stones in adults.

Journal Article Cochrane Database Syst Rev · November 12, 2020 BACKGROUND: Shock wave lithotripsy (SWL) is a widely used method to treat renal and ureteral stone. It fragments stones into smaller pieces that are then able to pass spontaneously down the ureter and into the bladder. Alpha-blockers may assist in promotin ... Full text Link to item Cite

Development and Performance of a Clinical Decision Support Tool to Inform Resource Utilization for Elective Operations.

Journal Article JAMA Netw Open · November 2, 2020 IMPORTANCE: Hospitals ceased most elective procedures during the height of coronavirus disease 2019 (COVID-19) infections. As hospitals begin to recommence elective procedures, it is necessary to have a means to assess how resource intensive a given case m ... Full text Link to item Cite

Rising occurrence of hypocitraturia and hyperoxaluria associated with increasing prevalence of stone disease in calcium kidney stone formers.

Journal Article Scand J Urol · October 2020 OBJECTIVE: To evaluate metabolic risk factors in calcium kidney stone formers from two different decades, comparing changes in metabolic profiles over time. METHODS: A retrospective analysis was performed of calcium kidney stone formers who underwent metab ... Full text Link to item Cite

Evidence-Based Clinical Practice 2.0: An Updated Primer for Urologists.

Journal Article Urol Pract · September 2020 INTRODUCTION: The practice of evidence-based medicine is important in optimizing patient care by ensuring that clinical decisions are made by considering the best available evidence that is tailored to each patient. We provide an update and guide in the pr ... Full text Link to item Cite

The Impact of Alternative Alkalinizing Agents on 24-Hour Urine Parameters.

Conference Urology · August 2020 OBJECTIVES: To determine if alternative alkalinizing agents lead to similar changes in 24-hour urine pH and citrate compared to potassium citrate (KCIT). Many stone formers cannot tolerate KCIT due to side effects or cost. In these patients, we have prescr ... Full text Link to item Cite

Shared Decision Making in Patients With Suspected Uncomplicated Ureterolithiasis: A Decision Aid Development Study.

Journal Article Acad Emerg Med · July 2020 OBJECTIVE: The objective was to develop a decision aid (DA) to facilitate shared decision making (SDM) around whether to obtain computed tomography (CT) imaging in patients presenting to the emergency department (ED) with suspected uncomplicated ureterolit ... Full text Link to item Cite

A protocol to reduce self-reported pain scores and adverse events following lumbar punctures in older adults.

Journal Article J Neurol · July 2020 OBJECTIVE: Lumbar punctures (LPs) are important for obtaining CSF in neurology studies but are associated with adverse events and feared by many patients. We determined adverse event rates and pain scores in patients prospectively enrolled in two cohort st ... Full text Link to item Cite

Re-Treatment after Ureteroscopy and Shock Wave Lithotripsy: A Population Based Comparative Effectiveness Study.

Journal Article J Urol · June 2020 PURPOSE: Shock wave lithotripsy and ureteroscopy are the most commonly performed surgeries for kidney and ureteral stones, but the comparative effectiveness of these interventions at the population level is unclear. We compared re-treatment for shock wave ... Full text Link to item Cite

Assessment of conservative dietary management as a method for normalization of 24-h urine pH in stone formers.

Journal Article Urolithiasis · April 2020 Low urine pH is a metabolic risk factor for stone formation. While medical therapy is typically prescribed (as urinary alkalinization), patients typically prefer dietary modifications. We aimed to assess capacity to alter urine pH with dietary management a ... Full text Link to item Cite

The MARBLE Study Protocol: Modulating ApoE Signaling to Reduce Brain Inflammation, DeLirium, and PostopErative Cognitive Dysfunction.

Journal Article J Alzheimers Dis · 2020 BACKGROUND: Perioperative neurocognitive disorders (PND) are common complications in older adults associated with increased 1-year mortality and long-term cognitive decline. One risk factor for worsened long-term postoperative cognitive trajectory is the A ... Full text Open Access Link to item Cite

Alpha-blockers after shock wave lithotripsy for renal or ureteral stones in adults

Journal Article COCHRANE DATABASE OF SYSTEMATIC REVIEWS · 2020 Full text Cite

Association of Patient and Visit Characteristics With Rate and Timing of Urologic Procedures for Patients Discharged From the Emergency Department With Renal Colic.

Journal Article JAMA Netw Open · December 2, 2019 IMPORTANCE: Little is known about the timing of urologic interventions in patients with renal colic discharged from the emergency department. Understanding patients' likelihood of a subsequent urologic intervention could inform decision-making in this popu ... Full text Link to item Cite

Nationwide Readmission Rates Following Percutaneous Nephrolithotomy: Does Age Matter?

Journal Article J Endourol · September 2019 Introduction/Objectives: Despite minimal evidence that evaluates the effect of age on percutaneous nephrolithotomy (PCNL) morbidity, pediatric and elderly patients are considered high-risk groups. Our objective was to assess the effect of the extremes of a ... Full text Link to item Cite

Imaging in Suspected Renal Colic: Systematic Review of the Literature and Multispecialty Consensus.

Journal Article J Urol · September 2019 PURPOSE: Renal colic is common and CT (computerized tomography) is frequently utilized when the diagnosis of kidney stone is suspected. CT is accurate, but exposes patients to ionizing radiation and has not been shown to alter either interventional approac ... Full text Link to item Cite

Imaging in Suspected Renal Colic: Systematic Review of the Literature and Multispecialty Consensus.

Journal Article Ann Emerg Med · September 2019 STUDY OBJECTIVE: Renal colic is common and computed tomography (CT) is frequently used when the diagnosis of kidney stone is suspected. CT is accurate but exposes patients to ionizing radiation and has not been shown to alter either interventional approach ... Full text Link to item Cite

Imaging in Suspected Renal Colic: Systematic Review of the Literature and Multispecialty Consensus.

Journal Article J Am Coll Radiol · September 2019 BACKGROUND: Renal colic is common, and CT is frequently utilized when the diagnosis of kidney stones is suspected. CT is accurate but exposes patients to ionizing radiation and has not been shown to alter either interventional approaches or hospital admiss ... Full text Link to item Cite

Editorial Commentary.

Journal Article Urol Pract · September 2019 Full text Link to item Cite

Alpha-blockers after shock wave lithotripsy for renal or ureteral stones in adults

Journal Article Cochrane Database of Systematic Reviews · August 9, 2019 This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the effects of alpha-blockers as adjuvant medical expulsive therapy in adults undergoing shockwave lithotripsy for renal or ureteral stones. ... Full text Cite

Parental Preferences for Vesicoureteral Reflux Treatment: A Crowd-sourced, Best-worst Scaling Study.

Journal Article Urology · June 2019 OBJECTIVE: To quantitatively evaluate parental preferences for the various treatments for vesicoureteral reflux using crowd-sourced best-worst scaling, a novel technique in urologic preference estimation. METHODS: Preference data were collected from a comm ... Full text Open Access Link to item Cite

The INTUIT Study: Investigating Neuroinflammation Underlying Postoperative Cognitive Dysfunction.

Journal Article J Am Geriatr Soc · April 2019 BACKGROUND/OBJECTIVES: Every year, up to 40% of the more than 16 million older Americans who undergo anesthesia/surgery develop postoperative cognitive dysfunction (POCD) or delirium. Each of these distinct syndromes is associated with decreased quality of ... Full text Open Access Link to item Cite

Psychiatric Diagnoses and Other Factors Associated with Emergency Department Return within 30 Days of Ureteroscopy.

Journal Article J Urol · March 2019 PURPOSE: Emergency department visits after ureteroscopy are costly and inconvenient. To better understand those at risk we aimed to identify patient demographic, medical and surgical factors associated with 30-day emergency department presentation followin ... Full text Link to item Cite

Editorial Comment.

Journal Article J Urol · December 2018 Full text Link to item Cite

Disproportionate Use of Inpatient Care by Older Adults With Kidney Stones.

Journal Article Urology · October 2018 OBJECTIVE: To describe variation in utilization and costs of inpatient care for patients with kidney stones, examining associations with older age. MATERIALS AND METHODS: Using the Nationwide Inpatient Sample we examined inpatient discharges with stone dia ... Full text Link to item Cite

Abdominal Radiography With Digital Tomosynthesis: An Alternative to Computed Tomography for Identification of Urinary Calculi?

Journal Article Urology · October 2018 OBJECTIVE: To compare the accuracy of plain abdominal radiography (kidneys, ureter, and bladder [KUB]) with digital tomosynthesis (DT) to noncontrast computed tomography (NCCT), the gold standard imaging modality for urinary stones. Due to radiation and co ... Full text Link to item Cite

Analgesic Prescribing Patterns for Acute Symptomatic Kidney Stones in Emergency Departments

Conference Journal of the American College of Surgeons · October 2018 Full text Cite

Just a Nudge: Applying Behavioral Incentives to Engage Residents in Quality Improvement Education

Conference Journal of the American College of Surgeons · October 2018 Full text Cite

Urology Consultation and Emergency Department Revisits for Children with Urinary Stone Disease.

Journal Article J Urol · July 2018 PURPOSE: We determined the association between urology consultation and emergency department revisits for children with urinary stones. MATERIALS AND METHODS: This retrospective cohort study included patients 18 years old or younger who presented to an eme ... Full text Link to item Cite

Real-world systemic therapy utilization in Medicare patients with locally advanced or metastatic urothelial carcinoma.

Conference Journal of Clinical Oncology · February 20, 2018 415 Background: Several immunotherapies recently have been approved for the treatment of locally advanced or metastatic bladder cancer that is prevalent in older adults. Utilization patterns in Medicare patients have not been exa ... Full text Cite

Comparison of Radiation Exposure from Fixed Table Fluoroscopy to a Portable C-Arm During Ureteroscopy.

Journal Article J Endourol · September 2017 INTRODUCTION: Current treatment practices within the field of endourology require the routine use of radiation exposure to provide adequate imaging during urologic procedures. One such procedure requiring repeated radiation exposure during treatment is ure ... Full text Link to item Cite

Editorial Comment.

Journal Article Urology · August 2017 Full text Link to item Cite

Should metabolic evaluation be performed in patients with struvite stones?

Journal Article Urolithiasis · April 2017 Previous studies suggested that patients with pure struvite calculi rarely have underlying metabolic abnormalities. Therefore, most of these patients do not undergo metabolic studies. We report our experience with these patients and their response to direc ... Full text Link to item Cite

The Diagnosis and Management of Patients with Renal Colic across a Sample of US Hospitals: High CT Utilization Despite Low Rates of Admission and Inpatient Urologic Intervention.

Journal Article PLoS One · 2017 OBJECTIVES: Symptomatic ureterolithiasis (renal colic) is a common Emergency Department (ED) complaint. Variation in practice surrounding the diagnosis and management of suspected renal colic could have substantial implications for both quality and cost of ... Full text Link to item Cite

Improved Reporting of Randomized Controlled Trials in the Urologic Literature.

Journal Article Eur Urol · December 2016 BACKGROUND: Well-designed randomized controlled trials (RCTs) have the potential to provide high-quality evidence to inform questions of therapy and prevention, but this potential is contingent on the use of appropriate methods and transparent reporting. O ... Full text Link to item Cite

Urinary Stone Disease: Advancing Knowledge, Patient Care, and Population Health.

Journal Article Clin J Am Soc Nephrol · July 7, 2016 Expanding epidemiologic and physiologic data suggest that urinary stone disease is best conceptualized as a chronic metabolic condition punctuated by symptomatic, preventable stone events. These acute events herald substantial future chronic morbidity, inc ... Full text Link to item Cite

NCCN Guidelines Insights: Prostate Cancer Early Detection, Version 2.2016.

Journal Article J Natl Compr Canc Netw · May 2016 The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Prostate Cancer Early Detection provide recommendations for prostate cancer screening in healthy men who have elected to participate in an early detection program. The NCCN Guidelines ... Full text Link to item Cite

A randomized, controlled trial of team-based competition to increase learner participation in quality-improvement education.

Journal Article Int J Qual Health Care · April 2016 OBJECTIVE: Several barriers challenge resident engagement in learning quality improvement (QI). We investigated whether the incorporation of team-based game mechanics into an evidence-based online learning platform could increase resident participation in ... Full text Link to item Cite

Digital Tomosynthesis: A Viable Alternative to Noncontrast Computed Tomography for the Follow-Up of Nephrolithiasis?

Journal Article J Endourol · April 2016 OBJECTIVE: Digital tomosynthesis (DT) is a new X-ray-based imaging technique that allows image enhancement with minimal increase in radiation exposure. The purpose of this study was to compare DT with noncontrast computed tomography (NCCT) and to evaluate ... Full text Link to item Cite

Use of ureteral access sheaths in ureteroscopy.

Journal Article Nat Rev Urol · March 2016 The ureteral access sheath (UAS) facilitates the use of flexible ureteroscopy, enabling improved minimally invasive management of complex upper urinary tract diseases. The UAS, which comes in a variety of diameters and lengths, is passed in a retrograde fa ... Full text Link to item Cite

Radiation Dosimetry for Ureteroscopy Patients: A Phantom Study Comparing the Standard and Obese Patient Models.

Journal Article J Endourol · January 2016 PURPOSE: To determine the effect of obesity on radiation exposure during simulated ureteroscopy. METHODS: A validated anthropomorphic adult male phantom with a body mass index (BMI) of approximately 24 kg/m(2), was positioned to simulate ureteroscopy. Padd ... Full text Link to item Cite

Prostate cancer early detection, version 2.2015: Clinical practice guidelines in oncology

Journal Article JNCCN Journal of the National Comprehensive Cancer Network · January 1, 2016 © National Comprehensive Cancer Network, Inc. 2015, All rights reserved.Prostate cancer represents a spectrum of disease that ranges from nonaggressive, slow-growing disease that may not require treatment to aggressive, fast-growing disease that does. The ... Cite

How do I set up a stone clinic?

Chapter · January 1, 2016 A comprehensive stone center can effectively manage complex urinary stone disease with the right tools. A collaborative team that includes a Urologist, a Nephrologist, a Dietician and a mid-level practitioner is optimal. The center should coordinate with a ... Full text Cite

NCCN Clinical Practice Guidelines Prostate Cancer Early Detection, Version 2.2015.

Journal Article J Natl Compr Canc Netw · December 2015 Prostate cancer represents a spectrum of disease that ranges from nonaggressive, slow-growing disease that may not require treatment to aggressive, fast-growing disease that does. The NCCN Guidelines for Prostate Cancer Early Detection provide a set of seq ... Full text Link to item Cite

Quality of Acute Care for Patients With Urinary Stones in the United States.

Journal Article Urology · November 2015 OBJECTIVE: To describe guideline adherence for patients with suspected upper tract stones. PATIENTS AND METHODS: We performed a cross-sectional analysis of visits recorded by the National Hospital Ambulatory Medical Care Survey (emergency department [ED] c ... Full text Link to item Cite

Radiation Exposure during the Evaluation and Management of Nephrolithiasis.

Journal Article J Urol · October 2015 PURPOSE: There is rising concern over the increasing amount of patient radiation exposure from diagnostic imaging and medical procedures. Patients with nephrolithiasis are at potentially significant risk for radiation exposure due to the need for imaging t ... Full text Link to item Cite

Estimating the nationwide, hospital based economic impact of pediatric urolithiasis.

Journal Article J Urol · May 2015 PURPOSE: The incidence of urolithiasis is increasing in children and adolescents but the economic impact of this problem is unclear. We examined 2 large databases to estimate the nationwide economic impact of pediatric urolithiasis. MATERIALS AND METHODS: ... Full text Link to item Cite

Emergency department revisits for patients with kidney stones in California.

Journal Article Acad Emerg Med · April 2015 OBJECTIVES: Kidney stones affect nearly one in 11 persons in the United States, and among those experiencing symptoms, emergency care is common. In this population, little is known about the incidence of and factors associated with repeat emergency departm ... Full text Link to item Cite

Clinical outcomes after ureteroscopic lithotripsy in patients who initially presented with urosepsis: matched pair comparison with elective ureteroscopy.

Journal Article J Endourol · December 2014 BACKGROUND AND PURPOSE: The outcomes of ureteroscopy (URS) after urgent decompression and antibiotics for patients who initially present with urosepsis because of obstructive urolithiasis have not been previously evaluated. The aim of this study was to com ... Full text Link to item Cite

Acute Renal Colic and Medical Expulsive Therapy

Chapter · November 1, 2014 Kidney stone disease is common; recurrence can be estimated at 52 % in 10 years [1]. Both blood and urine tests can be helpful for kidney stone prevention. Deciding when and what to order is often not very clear, and indications for such tests ... ... Cite

Prostate cancer early detection, version 1.2014. Featured updates to the NCCN Guidelines.

Journal Article J Natl Compr Canc Netw · September 2014 The NCCN Guidelines for Prostate Cancer Early Detection provide recommendations for men choosing to participate in an early detection program for prostate cancer. These NCCN Guidelines Insights highlight notable recent updates. Overall, the 2014 update rep ... Full text Link to item Cite

Comparative effectiveness of shock wave lithotripsy and ureteroscopy for treating patients with kidney stones.

Journal Article JAMA Surg · July 2014 IMPORTANCE: Shock wave lithotripsy (SWL) and ureteroscopy (URS) account for more than 90% of procedural interventions for kidney stones, which affect 1 in 11 persons in the United States. Efficacy data for SWL are more than 20 years old. Advances in URS, a ... Full text Link to item Cite

The impact of unplanned postprocedure visits in the management of patients with urinary stones.

Journal Article Surgery · May 2014 BACKGROUND: Unplanned follow-up care is the focus of intense health policy interest, as evidenced by recent financial penalties imposed under the Affordable Care Act. To date, however, unplanned postoperative care remains poorly characterized, particularly ... Full text Link to item Cite

Building a medical neighborhood in the safety net: an innovative technology improves hematuria workups.

Journal Article Urology · December 2013 OBJECTIVE: To analyze whether ereferral is associated with decreased time to completion of hematuria workup. METHODS: We included 100 individuals referred to Olive View-UCLA Medical Center for urologic consultation for hematuria. Half were referred before ... Full text Link to item Cite

Urologist attitudes toward end-of-life care.

Journal Article Urology · July 2013 OBJECTIVE: To examine urology trainees' views about the quality and current practices of end-of-life care and to explore strategies for improving integration and quality of care. METHODS: We conducted semi-structured interviews with 20 trainees from 4 inst ... Full text Link to item Cite

Practice patterns in the management of urinary lithiasis.

Journal Article Curr Urol Rep · April 2013 The prevalence of kidney stones is rising rapidly in the United States. Data from the Urologic Diseases in America project suggests that healthcare utilization and expenditures for treating patients with kidney stones are rising dramatically as well. Curre ... Full text Link to item Cite

Editorial comment.

Other J Urol · February 2013 Full text Link to item Cite

Epidemiology of stone disease

Chapter · January 1, 2013 Urinary lithiasis is a common condition in many parts of the world, with a peak prevalence of 5-10% in Western societies (Stamatelou et al. 2003; Lieske et al. 2006). While the symptomatic stone event garners most attention from patients and physicians ali ... Full text Cite

Urinary diversion in patients with spinal cord injury in the United States.

Journal Article Urology · December 2012 OBJECTIVE: To describe the patterns in the use of bladder augmentation and urinary diversion to manage urologic sequelae among patients with spinal cord injury in the United States. MATERIALS AND METHODS: Discharge estimates were derived from the Nationwid ... Full text Link to item Cite

Does variation in either age at start of therapy or duration of therapy make chemoprevention with finasteride cost-effective?

Journal Article Prostate Cancer Prostatic Dis · December 2012 BACKGROUND: Incremental cost-effectiveness ratios (ICERs) of finasteride for prostate cancer prevention are consistent with estimates beyond $100 000 per quality-adjusted life-year (QALY). The majority of these analyses are based on chemoprevention startin ... Full text Link to item Cite

Diagnostic tests in urology: an introduction.

Journal Article BJU Int · December 2012 What's known on the subject? and What does the study add? In our everyday practice as urologists, we often face diagnostic uncertainty that prompts us to perform a range of diagnostic tests to determine the probability that a patient has an underlying cond ... Full text Link to item Cite

Diagnostic tests in urology: urine cytology.

Journal Article BJU Int · December 2012 What's known on the subject? and What does the study add? Urine cytology is frequently used by urologists to evaluate patients with microscopic or gross haematuria. The results of urine cytology can be used as impetus to perform or triage further diagnosti ... Full text Link to item Cite

Prevalence of kidney stones in the United States.

Journal Article Eur Urol · July 2012 BACKGROUND: The last nationally representative assessment of kidney stone prevalence in the United States occurred in 1994. After a 13-yr hiatus, the National Health and Nutrition Examination Survey (NHANES) reinitiated data collection regarding kidney sto ... Full text Link to item Cite

Changes in initial treatment for prostate cancer among Medicare beneficiaries, 1999-2007.

Journal Article Int J Radiat Oncol Biol Phys · April 1, 2012 PURPOSE: In the absence of evidence from large clinical trials, optimal therapy for localized prostate cancer remains unclear; however, treatment patterns continue to change. We examined changes in the management of patients with prostate cancer in the Med ... Full text Link to item Cite

Video Imaging and Documentation

Chapter · January 5, 2012 Video imaging and documentation technologies have become commonplace in urologic practice. Improvements in video imaging technology have allowed significant advancements in endourology and minimally invasive urologic surgery. Digital endoscopes, 3D video i ... Full text Cite

Role of systematic reviews and meta-analysis in evidence-based clinical practice.

Journal Article Indian J Urol · October 2011 INTRODUCTION: Systematic reviews and meta-analyses of well-designed and executed randomized controlled trials have the potential to provide the highest levels of evidence to support diagnostic and therapeutic interventions in urology. MATERIALS AND METHODS ... Full text Link to item Cite

How to appraise the effectiveness of treatment.

Journal Article Indian J Urol · October 2011 INTRODUCTION: Advances in treatment and disease prevention occur frequently in urology. Urologists must identify a framework within which to evaluate these therapeutic innovations. MATERIALS AND METHODS: The evidence-based approach to critical appraisal is ... Full text Link to item Cite

Practice variation in the surgical management of urinary lithiasis.

Journal Article J Urol · July 2011 PURPOSE: Shock wave lithotripsy and ureteroscopy are highly effective treatments for urinary lithiasis. While stone size and location are primary determinants of therapy, little is known about other factors associated with treatment. We identified patient, ... Full text Link to item Cite

Bladder augmentation versus urinary diversion in patients with spina bifida in the United States.

Journal Article J Urol · July 2011 PURPOSE: Augmentation cystoplasty has replaced urinary diversion as the cornerstone of surgical management of refractory neurogenic bladder in patients with spina bifida. Other than single institution series little is known about practice patterns of bladd ... Full text Link to item Cite

Education and training in evidence-based urology.

Journal Article World J Urol · June 2011 OBJECTIVES: Urologists believe evidence-based clinical practice improves patient care. Competence in critical appraisal skills is necessary to successfully implement evidence-based practice. However, practicing urologists, urology program training director ... Full text Link to item Cite

Financial implications of changes in the initial treatment of prostate cancer among Medicare beneficiaries.

Journal Article J Clin Oncol · May 20, 2011 6115 Background: The traditional treament approaches for localized prostate cancer have included androgen suppression, watchful waiting, open radical prostatectomy, external beam radiation therapy and interstitial brachytherapy. In the last decade a number ... Link to item Cite

Effects of family history and genetic polymorphism on the cost-effectiveness of chemoprevention with finasteride for prostate cancer.

Journal Article J Urol · March 2011 PURPOSE: Improvement in the cost-effectiveness of chemoprevention for prostate cancer could be realized through the identification of patients at higher risk. We estimated the cost-effectiveness of prostate cancer chemoprevention across risk groups defined ... Full text Link to item Cite

Advanced topics in evidence-based urological oncology: using results of a subgroup analysis.

Journal Article Urol Oncol · 2011 BACKGROUND: Randomized, controlled trials are the cornerstone of evaluation for therapies in urologic oncology. Clinicians and investigators are frequently interested in whether treatment effects differ among subgroups of patients defined by clinically rel ... Full text Link to item Cite

Cost comparison among robotic, laparoscopic, and open hysterectomy for endometrial cancer.

Journal Article Obstet Gynecol · September 2010 OBJECTIVE: To use decision modeling to compare the costs associated with robotic, laparoscopic, and open hysterectomy for the treatment of endometrial cancer. METHODS: Three separate models were used, each with sensitivity analysis: 1) a societal perspecti ... Full text Link to item Cite

Clinical Trials in Urology

Chapter · July 9, 2010 Central to evidence-based practice is the concept of a hierarchy of evidence, with the randomized, controlled trial providing the highest level of evidence among individual studies. Several key features of randomized controlled trials provide methodologica ... Full text Cite

Reporting of harm in randomized controlled trials published in the urological literature.

Journal Article J Urol · May 2010 PURPOSE: Evidence-based decision making seeks to balance potential benefits and harms (adverse effects) of health care interventions for an individual patient. We determined the prevalence and completeness of harm reporting in randomized controlled trials ... Full text Link to item Cite

Stone forming risk factors in patients with type Ia glycogen storage disease.

Journal Article J Urol · March 2010 PURPOSE: Patients with type Ia glycogen storage disease have an increased recurrent nephrolithiasis rate. We identified stone forming risk factors in patients with type Ia glycogen storage disease vs those in stone formers without the disease. MATERIALS AN ... Full text Link to item Cite

Editorial Comment

Other Urology · April 1, 2009 Full text Cite

DOES RISING URINE PH INCREASE THE STONE FORMATION RATE?

Conference Journal of Urology · April 2009 Full text Cite

Impact of long-term potassium citrate therapy on urinary profiles and recurrent stone formation.

Journal Article J Urol · March 2009 PURPOSE: Potassium citrate therapy has become one of the cornerstones of medical stone management. We elucidated the long-term effects of potassium citrate on urinary metabolic profiles and its impact on stone formation rates. MATERIALS AND METHODS: We per ... Full text Link to item Cite

Evidence-based medicine training in residency: a survey of urology programme directors.

Journal Article BJU Int · February 2009 OBJECTIVE: To investigate whether and in what format urology residents receive formal training in evidence-based clinical practice. METHODS: In 2007 we conducted a survey of the Accreditation Council for Graduate Medical Education (ACGME)-accredited urolog ... Full text Link to item Cite

Radiation exposure in the acute and short-term management of urolithiasis at 2 academic centers.

Journal Article J Urol · February 2009 PURPOSE: Diagnostic imaging has a central role in the evaluation and management of urolithiasis. A variety of modalities are available, each with benefits and limitations. Without careful consideration of imaging modalities in quantity and type patients ma ... Full text Link to item Cite

Evaluating outcomes of enterocystoplasty in patients with spina bifida: a review of the literature.

Journal Article J Urol · December 2008 PURPOSE: The urological complications of spina bifida impose a significant burden of disability and disease. Therapy is focused on the bladder to achieve the primary goals of maintaining normal renal function and attaining urinary continence. When medical ... Full text Link to item Cite

Evaluating the evidence: statistical methods in randomized controlled trials in the urological literature.

Journal Article J Urol · October 2008 PURPOSE: Randomized controlled trials potentially provide the highest level of evidence to inform clinical decision making. Appropriate use of statistical methods is a critical aspect of all clinical research, including randomized controlled trials. We rep ... Full text Link to item Cite

Prostate-specific antigen screening among young men in the United States.

Journal Article Cancer · September 15, 2008 BACKGROUND: Disagreement exists on the use of prostate-specific antigen (PSA) tests for cancer-risk stratification in young men in the United States. Little is known about the use of PSA testing in these men. To understand policy implications of risk strat ... Full text Link to item Cite

How to use an article about a diagnostic test.

Journal Article J Urol · August 2008 PURPOSE: Urologists frequently confront diagnostic dilemmas, prompting them to select, perform and interpret additional diagnostic tests. Before applying a given diagnostic test the user should ascertain that the chosen test would indeed help decide whethe ... Full text Link to item Cite

Barriers to the practice of evidence-based urology.

Journal Article J Urol · June 2008 PURPOSE: We investigated urologist perceptions of barriers to implementing evidence-based medicine in clinical practice. MATERIALS AND METHODS: In April 2005 an Internet survey was conducted to assess American Urological Association member attitudes toward ... Full text Link to item Cite

The critical use of population-based medical databases for prostate cancer research.

Journal Article Curr Opin Urol · May 2008 PURPOSE OF REVIEW: Population-based investigations comprise a significant portion of the prostate cancer literature and contribute considerably to our knowledge of this disease. It is important to recognize, however, the inherent limitations of observation ... Full text Link to item Cite

Prostate cancer in the Baby Boomer generation: results from CaPSURE.

Journal Article Urology · December 2007 OBJECTIVES: Baby Boomers (those born in 1946 to 1964) are thought to place a high value on quality of life, and have a higher propensity to consume healthcare services than previous generations. We sought to characterize prostate cancer (CaP) presentation ... Full text Link to item Cite

Predicting unilateral prostate cancer based on biopsy features: implications for focal ablative therapy--results from the SEARCH database.

Journal Article J Urol · October 2007 PURPOSE: For men with low risk prostate cancer it was recently proposed that ablative treatment to the affected side may decrease morbidity, while maintaining good oncological outcomes. However, few studies have assessed the correlation between biopsy para ... Full text Link to item Cite

Evidence based clinical practice: a primer for urologists.

Journal Article J Urol · September 2007 PURPOSE: Evidence based clinical practice has been defined as the conscientious, explicit and judicious use of the current best evidence in making decisions about the care of individual patients. It refers to a broad set of principles and methods intended ... Full text Link to item Cite

Changing gender prevalence of stone disease.

Journal Article J Urol · March 2007 PURPOSE: Recent studies suggest that the incidence of renal stone formation has been increasing and the male predominance of nephrolithiasis is decreasing, which may be due to changes in diet and lifestyle. We examined changes in the prevalence by gender o ... Full text Link to item Cite

A critical assessment of the quality of reporting of randomized, controlled trials in the urology literature.

Journal Article J Urol · March 2007 PURPOSE: Randomized, controlled trials are the gold standard for evidence based assessment of therapeutic interventions. In 1996 the Consolidated Standards of Reporting Trials statement was published in an effort to standardize the reporting of clinical tr ... Full text Link to item Cite

Relationship between body mass index and prostate cancer screening in the United States.

Journal Article J Urol · February 2007 PURPOSE: Obesity is associated with more advanced disease and worse outcomes in men with prostate cancer. To our knowledge the relationship between obesity and prostate cancer screening behavior in men 40 or older is unknown. Thus, we examined associations ... Full text Link to item Cite

Interpreting statistics in the urological literature.

Journal Article J Urol · November 2006 PURPOSE: Knowledge of statistical terminology and the ability to critically interpret research findings are critical skills in the practice of evidence based medicine. MATERIALS AND METHODS: We provide a series of nontechnical explanations of basic statist ... Full text Link to item Cite

Evidence-based medicine: a survey of American Urological Association members.

Journal Article J Urol · September 2006 PURPOSE: We investigated the attitudes and opinions of urologists toward evidence-based medicine. MATERIALS AND METHODS: In April of 2005 we contacted members of the American Urological Association listed with an e-mail address to participate in a web base ... Full text Link to item Cite

Prostate specific antigen testing in men older than 75 years in the United States.

Journal Article J Urol · August 2006 PURPOSE: Although there is general agreement that men older than 75 years are unlikely to benefit from prostate specific antigen testing, patient reported testing rates in these patients exceed 30%. We examined physician reported PSA testing in elderly men ... Full text Link to item Cite

Clinical utilization of digital rectal examination and fecal occult blood testing upon hospital admission.

Journal Article J Clin Gastroenterol · 2006 GOALS: The objective of our investigation was to examine the clinical utilization of digital rectal examination (DRE) and fecal occult blood testing (FOBT) at hospital admission. BACKGROUND: DRE at the time of hospital admission is frequently accompanied b ... Full text Link to item Cite

Local cost structures and the economics of robot assisted radical prostatectomy.

Journal Article J Urol · December 2005 PURPOSE: Robot assisted prostatectomy (RAP) is more costly than traditional radical retropubic prostatectomy (RRP) under the cost structures at certain hospitals. However, this finding may not be the case in all care settings. We investigated the sensitivi ... Full text Link to item Cite

Effect of ureteral access sheath on stone-free rates in patients undergoing ureteroscopic management of renal calculi.

Journal Article Urology · August 2005 OBJECTIVES: To evaluate the effect of ureteral access sheaths (UASs) on stone-free rates (SFRs) during ureteroscopic treatment of renal calculi. Several advantages of UASs during flexible ureteroscopy have been documented. However, no study has evaluated t ... Full text Link to item Cite

1099: Changing Gender Prevalence of Nephrolithiasis

Conference Journal of Urology · April 2005 Full text Cite