Factor VIIa for Annulus Rupture After Transcatheter Aortic Valve Replacement.

Journal Article (Journal Article)

Over the last decade, transcatheter aortic valve replacement (TAVR) has emerged as an effective treatment for inoperable and selected high surgical-risk patients with aortic stenosis. However, management of procedural complications with TAVR represents a major challenge as most TAVR patients carry prohibitive or high-risk of mortality with open surgical conversion. Here we present a case of TAVR complicated by aortic annulus rupture that was successfully managed nonoperatively by pericardial drainage, blood product transfusion, and adjunctive administration of recombinant activated factor VIIa.

Full Text

Duke Authors

Cited Authors

  • Keenan, JE; Vavalle, JP; Ganapathi, AM; Wang, H; Harrison, JK; Wang, A; Hughes, GC

Published Date

  • July 2015

Published In

Volume / Issue

  • 100 / 1

Start / End Page

  • 313 - 315

PubMed ID

  • 26140778

Electronic International Standard Serial Number (EISSN)

  • 1552-6259

Digital Object Identifier (DOI)

  • 10.1016/j.athoracsur.2014.09.063


  • eng

Conference Location

  • Netherlands