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Factor VIIa for Annulus Rupture After Transcatheter Aortic Valve Replacement.

Publication ,  Journal Article
Keenan, JE; Vavalle, JP; Ganapathi, AM; Wang, H; Harrison, JK; Wang, A; Hughes, GC
Published in: Ann Thorac Surg
July 2015

Over the last decade, transcatheter aortic valve replacement (TAVR) has emerged as an effective treatment for inoperable and selected high surgical-risk patients with aortic stenosis. However, management of procedural complications with TAVR represents a major challenge as most TAVR patients carry prohibitive or high-risk of mortality with open surgical conversion. Here we present a case of TAVR complicated by aortic annulus rupture that was successfully managed nonoperatively by pericardial drainage, blood product transfusion, and adjunctive administration of recombinant activated factor VIIa.

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Published In

Ann Thorac Surg

DOI

EISSN

1552-6259

Publication Date

July 2015

Volume

100

Issue

1

Start / End Page

313 / 315

Location

Netherlands

Related Subject Headings

  • Transcatheter Aortic Valve Replacement
  • Rupture
  • Respiratory System
  • Recombinant Proteins
  • Humans
  • Female
  • Factor VIIa
  • Aortic Valve
  • Aged, 80 and over
  • 3202 Clinical sciences
 

Citation

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Keenan, J. E., Vavalle, J. P., Ganapathi, A. M., Wang, H., Harrison, J. K., Wang, A., & Hughes, G. C. (2015). Factor VIIa for Annulus Rupture After Transcatheter Aortic Valve Replacement. Ann Thorac Surg, 100(1), 313–315. https://doi.org/10.1016/j.athoracsur.2014.09.063
Keenan, Jeffrey E., John P. Vavalle, Asvin M. Ganapathi, Hanghang Wang, J Kevin Harrison, Andrew Wang, and G Chad Hughes. “Factor VIIa for Annulus Rupture After Transcatheter Aortic Valve Replacement.Ann Thorac Surg 100, no. 1 (July 2015): 313–15. https://doi.org/10.1016/j.athoracsur.2014.09.063.
Keenan JE, Vavalle JP, Ganapathi AM, Wang H, Harrison JK, Wang A, et al. Factor VIIa for Annulus Rupture After Transcatheter Aortic Valve Replacement. Ann Thorac Surg. 2015 Jul;100(1):313–5.
Keenan, Jeffrey E., et al. “Factor VIIa for Annulus Rupture After Transcatheter Aortic Valve Replacement.Ann Thorac Surg, vol. 100, no. 1, July 2015, pp. 313–15. Pubmed, doi:10.1016/j.athoracsur.2014.09.063.
Keenan JE, Vavalle JP, Ganapathi AM, Wang H, Harrison JK, Wang A, Hughes GC. Factor VIIa for Annulus Rupture After Transcatheter Aortic Valve Replacement. Ann Thorac Surg. 2015 Jul;100(1):313–315.
Journal cover image

Published In

Ann Thorac Surg

DOI

EISSN

1552-6259

Publication Date

July 2015

Volume

100

Issue

1

Start / End Page

313 / 315

Location

Netherlands

Related Subject Headings

  • Transcatheter Aortic Valve Replacement
  • Rupture
  • Respiratory System
  • Recombinant Proteins
  • Humans
  • Female
  • Factor VIIa
  • Aortic Valve
  • Aged, 80 and over
  • 3202 Clinical sciences