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Andrew Wang

Professor of Medicine
Medicine, Cardiology
Duke Box 3428, Durham, NC 27710
HAFS Building, Room 8678A, 2301 Erwin Road, Durham, NC 27710

Overview


Structural heart diseases, including heart valve diseases and hypertrophic cardiomyopathy

Current Appointments & Affiliations


Professor of Medicine · 2012 - Present Medicine, Cardiology, Medicine
Vice Chief for Clinical Services · 2019 - Present Medicine, Cardiology, Medicine

In the News


Published September 6, 2016
When Surgery Is Too Risky, A Clip Can Repair Leaky Heart Valve

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Recent Publications


Early outcomes of off-label transcatheter tricuspid valve repair/replacement in the STS/ACC TVT registry.

Journal Article Am Heart J · May 2026 BACKGROUND: Transcatheter tricuspid valve interventions (TTVI) have expanded with the recent FDA approval of both replacement transcatheter tricuspid valve replacement (TTVR) and edge-to-edge repair (T-TEER) devices. However, the volume and outcomes of com ... Full text Link to item Cite

Aficamten in Obstructive Hypertrophic Cardiomyopathy: A Multidomain, Patient-Level Analysis of the MAPLE-HCM Trial.

Journal Article J Am Coll Cardiol · March 3, 2026 BACKGROUND: For >60 years, beta-blockers have been first-line therapy for symptomatic obstructive hypertrophic cardiomyopathy (oHCM), although limited data support this recommendation. The MAPLE-HCM trial showed greater improvement in exercise capacity and ... Full text Link to item Cite

Effect of Aficamten vs Metoprolol on Patient-Reported Health Status in Obstructive Hypertrophic Cardiomyopathy.

Journal Article J Am Coll Cardiol · March 3, 2026 BACKGROUND: The cardiac myosin inhibitor aficamten was significantly more effective than metoprolol at improving exercise tolerance in MAPLE-HCM (Metoprolol vs Aficamten in Patients with LVOT Obstruction on Exercise Capacity in HCM), a head-to-head, intern ... Full text Link to item Cite
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Recent Grants


Discover- HCM

Clinical TrialPrincipal Investigator · Awarded by Bristol-Myers Squibb Company · 2022 - 2030

Machine Learning Guided Precision Genetic Testing for Identification of Monogenic Cardiovascular Disorders

ResearchCo Investigator · Awarded by National Heart, Lung, and Blood Institute · 2024 - 2028

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Education


Duke University · 1990 M.D.