Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • M.D., Duke University 1995
• 

  Duke Appointment History

  • Associate Professor of Surgery, Surgery, Cardiovascular and Thoracic Surgery, Surgery 2011 - 2015
  • Assistant Professor of Surgery, Surgery, Cardiovascular and Thoracic Surgery, Surgery 2005 - 2011
  • Instructor, Temporary in the Department of Surgery, Surgery, Cardiovascular and Thoracic Surgery, Surgery 2005
• Research
• 

  Selected Grants

  • Mitrofolow Aortic Pericardial Heart Valve with Phospholipid Reduction Treatment awarded by Sorin Group 2015 - 2025
  • PARTNER II awarded by Edwards Lifesciences Corporation 2014 - 2025
  • Gore TAG (TBE Device) awarded by W. L. Gore & Associates, Inc. 2017 - 2024
  • TAVR in Low Risk Patients awarded by Medtronic, Inc. 2016 - 2023
  • Valiant EVO US Clinical Trial awarded by Medtronic, Inc. 2016 - 2021
  • Cognitive Effects of Body Temperature During Hypothermic Circulatory Arrest awarded by National Institutes of Health 2016 - 2021
  • Study of the Relay Thoracic Stent-Graft with Plus Delivery System awarded by Bolton Medical, Inc. 2014 - 2020
  • Hanghang Wang Fellowship awarded by Thoracic Surgery Foundation for Research and Education 2015 - 2017
  • Evaluation of the Thoraflex Hybrid Device awarded by Terumo Medical Corporation 2016 - 2017
  • CardioCel Tri-leaflet Repair Study awarded by Admedus Limited 2016
  • Chart Review to Investigate Bleeding Risk and Blood Transfusion Requirements awarded by CSL Behring LLC 2014 - 2015
  • Study of GSK1278863 in Patients Undergoing THoracic Aortic Aneurysm Repair awarded by GlaxoSmithKline 2013 - 2015
  • Transmyocardial Laser Revascularization: Mechanisms . . . awarded by National Institutes of Health 1998 - 2000
• Publications & Artistic Works
• 

  Selected Publications

  • Book Sections

    • Williams, JB, and Hughes, GC. "TEVAR Complicated by Acute Retrograde Dissection." In Current Vascular Surgery. : People's Medical Publishing House, 2013. (Chapter)
    • Lee, TC, and Hughes, GC. "Complications of thoracic endovascular stent grafts." In Cardiothoracic Surgery Review, 581-588. January 5, 2012.
    • Stafford-Smith, M, Hughes, C, Shaw, AD, and Swaminathan, M. "Renal protection strategies." In Anesthesia and Perioperative Care for Aortic Surgery, 329-347. December 1, 2011.  Full Text
    • Hughes, GC, and Lowe, JE. "Animal Models of Acute and Chronic Coronary Ischemia: Effects of TMR on Perfusion and Left Ventricular Function." In Myocardial Laser Revascularization, 65-78. November 5, 2007.  Full Text

  • Conference Papers

    • Cox, M, Bishawi, M, Nag, U, Ranney, D, Yerokun, B, Wang, A, and Hughes, GC. "IMPACT OF POST-OPERATIVE ATRIAL FIBRILLATION ON EARLY AND LATE OUTCOMES AFTER PROXIMAL AORTIC SURGERY." March 2018.  Full Text
    • Ranney, DN, Cox, ML, Yerokun, BA, Benrashid, E, McCann, RL, and Hughes, GC. "Long-term results of endovascular repair for descending thoracic aortic aneurysms." February 2018.  Full Text
    • Voigt, SL, Bishawi, M, McCann, RL, and Hughes, GC. "Long-term Outcomes of Carotid-Subclavian Bypass in the Setting of Thoracic Endovascular Aortic Repair." January 2018.  Link to Item
    • Wagner, MA, Wang, H, Benrashid, E, Keenan, JE, Krishnamurthy, Y, Levy, JH, Welsby, IJ, and Hughes, GC. "Protocolized Hemostatic Factor Use in Major Thoracic Aortic Surgery." Scientific Sessions of the American-Heart-Association / Resuscitation Science Symposium. Anaheim, CA. November 11, 2017 - November 15, 2017.: LIPPINCOTT WILLIAMS & WILKINS, November 14, 2017.  Link to Item
    • Wang, A, Yerokun, B, Li, Z, Kosinski, A, Cox, ML, Gulack, BC, Sherwood, MW, Lopes, RD, Thourani, V, Kirtane, AJ, Holmes, D, Hughes, GC, Harrison, JK, Smith, PK, and Vemulapalli, S. "Fragmented Care Following Transcatheter Aortic Valve Replacement is Associated With Increased 1-year Mortality and Readmission." Scientific Sessions of the American-Heart-Association / Resuscitation Science Symposium. Anaheim, CA. November 11, 2017 - November 15, 2017.: LIPPINCOTT WILLIAMS & WILKINS, November 14, 2017.  Link to Item
    • Yerokun, BA, Karhausen, J, Ranney, DN, Benrashid, E, Wang, H, Keenan, J, Schroder, J, Daneshmand, M, Gaca, JG, and Hughes, GC. "Does Deeper Hypothermia Reduce the Risk of Acute Kidney Injury After Circulatory Arrest for Aortic Arch Surgery?." Scientific Sessions of the American-Heart-Association / Resuscitation Science Symposium. Anaheim, CA. November 11, 2017 - November 15, 2017.: LIPPINCOTT WILLIAMS & WILKINS, November 14, 2017.  Link to Item
    • Wang, H, Wagner, M, Benrashid, E, Keenan, J, Wang, A, Ranney, D, Yerokun, B, Gaca, JG, McCann, RL, and Hughes, GC. "Outcomes of Reoperation After Acute Type A Aortic Dissection: Implications for Index Repair Strategy." October 3, 2017.  Full Text
    • Fanaroff, AC, Manandhar, P, Holmes, D, Cohen, D, Harrison, JK, Hughes, GC, Thourani, V, Mack, M, Jones, W, and Vemulapalli, S. "PERIPHERAL ARTERY DISEASE AND TRANSCATHETER AORTIC VALVE REPLACEMENT OUTCOMES: A REPORT FROM THE STS/TVT REGISTRY." March 21, 2017.  Link to Item
    • Kochar, A, Li, Z, Harrison, J, Hughes, GC, Thourani, V, Mack, M, Cohen, D, Peterson, E, Jones, W, and Vemulapalli, S. "STROKE AND CARDIOVASCULAR OUTCOMES IN PATIENTS WITH CAROTID DISEASE UNDERGOING TAVR: INSIGHTS FROM THE STS/TVT REGISTRY." March 21, 2017.  Link to Item
    • Ranney, D, Benrashid, E, Yerokun, B, Wang, H, Harrison, J, Wang, A, Kiefer, T, and Hughes, GC. "SURGERY FOR PATIENTS WITH BICUSPID AORTOPATHY: VALIDATION OF THE 2016 ACC/AHA GUIDELINES CLARIFICATION." March 21, 2017.  Link to Item
    • Vora, A, Dai, DD, Matsouaka, R, Harrison, JK, Hughes, GC, Sherwood, M, Piccini, J, Cohen, D, Holmes, D, Bhardwaj, B, Thourani, V, Peterson, E, and Vemulapalli, S. "NEW-ONSET ATRIAL FIBRILLATION FOLLOWING TRANSCATHETER AORTIC VALVE REPLACEMENT: INCIDENCE, ANTICOAGULANT STRATEGY, AND OUTCOMES." 66th Annual Scientific Session and Expo of the American-College-of-Cardiology (ACC). Washington, DC. March 17, 2017 - March 19, 2017. ELSEVIER SCIENCE INC, March 21, 2017.  Link to Item
    • Wang, A, Wang, H, Benrashid, E, Ranney, D, Yerokun, B, Sherwood, MW, Gaca, J, Kiefer, T, Wang, A, Harrison, J, and Hughes, GC. "PREDICTORS OF MORTALITY AFTER TAVR IN A "REAL WORLD" SETTING." 66th Annual Scientific Session and Expo of the American-College-of-Cardiology (ACC). Washington, DC. March 17, 2017 - March 19, 2017. ELSEVIER SCIENCE INC, March 21, 2017.  Link to Item
    • Yerokun, BA, Bishawi, M, Williams, AR, Ranney, DN, Benrashid, E, McCann, RL, and Hughes, GC. "Impact of Early versus Late Timing of TEVAR on Aortic Remodeling and Long-Term Survival Following Type B Aortic Dissection." January 2017.  Full Text
    • Popma, JJ, Harrison, JK, Hughes, GC, Kodali, S, George, I, Oh, J, Slater, J, Williams, M, and Gilbert, C. "Transcatheter Aortic Valve Replacement with a Repositionable Self-expanding Bioprosthesis in Patients With Severe Aortic Stenosis at High Risk for Surgery: One-Year Results from the Evolut R US Pivotal Study." November 1, 2016.  Full Text  Link to Item
    • Sherwood, M, Xiang, Q, Matsouaka, R, Hughes, GC, Vemulapalli, S, Vora, A, Peterson, E, and Rao, S. "Incidence and Outcomes of Vascular Complications and Bleeding Events in Patients undergoing TAVR in contemporary US practice: Insights from the STS/ACC TVT Registry (R)." November 1, 2016.  Full Text  Link to Item
    • Benrashid, E, Wang, H, Andersen, ND, Keenan, JE, McCann, RL, and Hughes, GC. "An Integrated Approach to Thoracoabdominal Aortic Aneurysm Repair: Complimentary Roles of Open and Hybrid Approaches." January 2016.  Full Text
    • Cheruku, S, Kertai, MD, Qi, W, Li, Y-J, Hughes, GC, Mathew, JP, and Karhausen, J. "Mast Cell Activation During Aortic Repair Requiring Circulatory Arrest is Associated With Hemodynamic Instability and Indications of End-Organ Injury." November 10, 2015.  Link to Item
    • Sherwood, MW, Vemulapalli, S, Vora, AN, Dai, DD, Halim, S, Kiefer, TL, Hughes, GC, Harrison, JK, and Peterson, ED. "National Variation in Post-tavr Antithrombotic Therapy Utilization in Patients With Atrial Fibrillation: Insights From the Sts/acc Tvt Registry (R)." LIPPINCOTT WILLIAMS & WILKINS, November 10, 2015.  Link to Item
    • Vora, AN, Harrison, JK, Dunning, A, Schulte, P, Sherwood, MW, Kisslo, J, Hughes, GC, Alenezi, FA, Velazquez, E, and Samad, Z. "TAVR Versus Medical Management Among Patients With Severe Aortic Stenosis and Left Ventricular Systolic Dysfunction." LIPPINCOTT WILLIAMS & WILKINS, November 10, 2015.  Link to Item
    • Harrison, JK, Hughes, G, Reardon, MJ, Stoler, R, Grayburn, P, Hebeler, RF, and Popma, J. "TCT-94 Balloon Post-Dilation of the Self-Expanding CoreValve Transcatheter Aortic Valve Bioprosthesis: Procedural Results and In Hospital Outcomes from 3532 patients in the CoreValve US Pivotal and Continued Access Trials." October 2015.  Full Text
    • Sherwood, MW, Vora, AN, Vemulapalli, S, Dai, D, Halim, S, Kiefer, T, Hughes, GC, and Harrison, JK. "TCT-103 National variation in post-TAVR antithrombotic therapy utilization and associated outcomes: Insights from the STS/ACC TVT Registry®." October 2015.  Full Text
    • Benrashid, E, Wang, H, Keenan, JE, Andersen, ND, Meza, JM, McCann, RL, and Hughes, GC. "SS7. Hybrid Repair of the Aortic Arch: Long-Term Outcomes After a Decade of Intervention." June 2015.  Full Text
    • Schechter, MA, Ganapathi, AM, Englum, BR, Keenan, JE, Wang, H, Hughes, GC, and McCann, RL. "PC46. Improved Long-Term Survival of EVAR Compared to Open Repair." June 2015.  Full Text
    • Ganapathi, AM, Englum, BR, Schechter, MA, Vavalle, JP, Harrison, JK, McCann, RL, and Hughes, GC. "Role of cardiac evaluation before thoracic endovascular aortic repair." November 2014.  Full Text
    • Ganapathi, A, Peterson, M, Lindsay, ME, Patel, H, Pyeritz, R, Trimarchi, S, Hutchison, S, Harris, K, Greason, K, Ota, T, Montgomery, D, Nienaber, C, Eagle, K, Isselbacher, E, and Hughes, GC. "TYPE A AORTIC DISSECTION AT A DIAMETER <5.5 CENTIMETERS: DOES MODERATE ENLARGEMENT OF THE AORTIC ROOT CARRY GREATER RISK THAN MODERATE SUPRACORONARY ASCENDING AORTIC ENLARGEMENT?." April 2014.  Full Text
    • Watson, KA, Ganapathi, AM, Schechter, MA, Englum, BR, McCann, RL, and Hughes, GC. "Repair of Mycotic Thoracoabdominal Aortic Aneurysm Following BCG Treatment." December 2013.  Full Text  Link to Item
    • Di Eusanio, M, Trimarchi, S, Peterson, MD, Myrmel, T, Hughes, GC, Korach, A, Sundt, TM, Greason, K, Appoo, JJ, Milner, R, Montgomery, DG, Isselbacher, EM, Eagle, KA, Nienaber, CA, and Patel, HJ. "Root Replacement versus More Conservative Management During Type A Acute Aortic Dissection Repair: Insights From the International Registry of Acute Aortic Dissection." November 26, 2013.  Link to Item
    • Vavalle, JP, Cowper, P, Nelson, JA, Hurwitz, L, Hughes, GC, Wang, A, Gaca, JG, Kiefer, T, Halim, S, Alexander, JH, and Harrison, JK. "Inpatient and Outpatient Resource Utilization in the Evaluation and Management of Patients With Aortic Stenosis Being Considered for Transcatheter Aortic Valve Replacement (TAVR)." November 26, 2013.  Link to Item
    • Schechter, MA, Ganapathi, AM, Englum, BR, Hanna, JM, McCann, R, and Hughes, GC. "Frailty Does Not Increase Risk in Thoracic Endovascular Aortic Repair." May 2013.  Full Text  Link to Item
    • Hanna, JM, Fattori, R, Gilon, D, Upchurch, G, Harris, K, Bossone, E, Voehringer, M, Greason, K, Fillinger, M, Desai, N, Montgomery, D, Isselbacher, E, Nienaber, C, Eagle, K, and Hughes, GC. "PREDICTORS OF IN-HOSPITAL SURVIVAL WITH MEDICAL MANAGEMENT FOR TYPE A ACUTE AORTIC DISSECTION: IMPLICATIONS FOR SUBOPTIMAL SURGICAL CANDIDATES." March 12, 2013.  Full Text  Link to Item
    • Hanna, JM, Ganapathi, A, Andersen, N, McCann, RL, and Hughes, GC. "Long-Term Results for Endovascular Repair of Acute Complicated Type B Aortic Dissection." December 2012.  Full Text  Link to Item
    • Vavalle, JP, Phillips, H, Holleran, S, Wang, A, O'Connor, CM, Smith, PK, Hughes, GC, Harrison, JK, and Patel, MR. "Access to Care: Geographical Variations in the Diagnosis and Treatment of Aortic Stenosis in North Carolina." November 20, 2012.  Link to Item
    • Andersen, ND, Hanna, JM, Bhattacharya, SD, Williams, JB, Gaca, JG, McCann, RL, and Hughes, GC. "Insurance status predicts non-elective case status but not outcomes of thoracic aortic operations." September 2012.  Full Text
    • Hanna, JM, Andersen, ND, Shah, AA, Harrison, JK, McCann, RL, and Hughes, GC. "Open femoral access for transcatheter aortic intervention leads to fewer major vascular complications." September 2012.  Full Text  Link to Item
    • Bossone, E, Korach, A, Fattori, R, Hughes, GC, Tsai, TT, Montgomery, DG, Eagle, KA, Nienaber, CA, Isselbacher, EM, Suzuki, T, and Aortic, IRA. "Racial differences in acute aortic dissection: insights from the International Registry of Acute Aortic Dissection." August 2012.  Link to Item
    • Shah, AA, Craig, DM, Williams, JB, Bhattacharya, SD, Andersen, ND, Shah, SH, McCann, RL, and Hughes, GC. "PS24. Risk Factors for Non-Procedure Related Mortality One Year after Thoracic Endovascular Aortic Repair." June 2011.  Full Text
    • Williams, JB, Piccini, JP, Bhattacharya, SD, Andersen, ND, McCann, RL, and Hughes, GC. "PS28. Retrograde Ascending Aortic Dissection as an Early Complication of Thoracic Endovascular Aortic Repair." June 2011.  Full Text
    • Shah, AA, Williams, JB, Phillips-Bute, B, Bartz, R, Hughes, GC, and Welsby, IJ. "Pulmonary Dysfunction After Thoracic Aortic Surgery Utilizing Deep Hypothermic Circulatory Arrest." : AMER THORACIC SOC, January 1, 2011.  Link to Item
    • Hughes, GC, Zhao, Y, Rankin, JS, O'Brien, S, Bavaria, JE, Wolfe, WG, Gaca, JG, Gammie, JS, Shahian, DM, and Smith, PK. "Effects of Institutional Volumes on Operative Outcomes for Combined Aortic Valve and Ascending Aortic Surgery." November 23, 2010.  Link to Item
    • Mehta, RH, Honeycutt, E, Hughes, GC, and Jr, SMH. "Relationship of Time Interval Between Elective Coronary Artery Bypass Surgery and Cardiac Catheterization With the Risk of Post-Surgical Acute Kidney Injury." November 23, 2010.  Link to Item
    • Patel, MB, Bhattacharya, SD, Williams, JB, Sweeney, TE, Vaslef, SN, Hughes, GC, Kuo, PC, and Lawson, JH. "Six Year, Single Institution, off-Label Use of Recombinant Factor VIIa." 52nd Annual Meeting of the American-Society-of-Hematology (ASH). Orlando, FL. December 4, 2010 - December 7, 2010. AMER SOC HEMATOLOGY, November 19, 2010.  Link to Item
    • Ibrahim, IA, Hassan, A, Abdel-Wahab, Z, El-ghanam, A, Hughes, GC, Thomas, R, Taylor, D, Lowe, JE, and Abel-aleem, S. "Depression of cytosolic heart fatty acid binding protein (H-FABP) expression in adriamycin-induced cardiomyopathy and its reversal by L-carnitine." March 15, 1999.  Link to Item
    • Abdel-aleem, S, Kishk, AM, Hassan, AG, Hughes, GC, Ibrahim, IA, Taylor, DA, and Lowe, JE. "The enhancement of insulin-sensitive glucose transporter expression by chronic inhibition of fatty acid oxidation in the diabetic rat heart." October 27, 1998.  Link to Item
    • Hughes, GC, Landolfo, KP, Lowe, JE, Coleman, RB, and Donovan, CL. "Perioperative morbidity and mortality following transmyocardial laser revascularization." February 1998.  Full Text  Link to Item
    • Hughes, GC, Landolfo, KP, Lowe, JE, Coleman, RB, and Donovan, CL. "Detection of perioperative ischemia following transmyocardial laser revascularization." February 1998.  Full Text  Link to Item
    • St Louis, JD, Hendrickson, SC, Kypson, AP, Hughes, GC, Coleman, RE, Donovan, CL, Degrado, TR, Seabage, L, Abdel-aleem, S, Landolfo, KP, and Lowe, JE. "An experiment model of myocardial hibernation." February 1998.  Full Text  Link to Item

  • Journal Articles

    • Ranney, DN, Yerokun, BA, Benrashid, E, Bishawi, M, Williams, A, McCann, RL, and Hughes, GC. "Outcomes of Planned Two-Stage Hybrid Aortic Repair With Dacron-Replaced Proximal Landing Zone." The Annals of Thoracic Surgery 106, no. 4 (October 2018): 1136-1142.  Full Text
    • Gleason, TG, Reardon, MJ, Popma, JJ, Deeb, GM, Yakubov, SJ, Lee, JS, Kleiman, NS, Chetcuti, S, Hermiller, JB, Heiser, J, Merhi, W, Zorn, GL, Tadros, P, Robinson, N, Petrossian, G, Hughes, GC, Harrison, JK, Conte, JV, Mumtaz, M, Oh, JK, Huang, J, Adams, DH, and CoreValve U.S. Pivotal High Risk Trial Clinical Investigators, . "Self-Expanding Transcatheter Aortic Valve Replacement or Surgical Valve Replacement in High-Risk Patients: 5-Year Outcomes." Journal of the American College of Cardiology (September 18, 2018).  Full Text
    • Vora, AN, Dai, D, Matsuoka, R, Harrison, JK, Hughes, GC, Sherwood, MW, Piccini, JP, Bhardwaj, B, Lopes, RD, Cohen, D, Holmes, DR, Thourani, VH, Peterson, E, Kirtane, A, Kapadia, S, and Vemulapalli, S. "Incidence, Management, and Associated Clinical Outcomes of New-Onset Atrial Fibrillation Following Transcatheter Aortic Valve Replacement: An Analysis From the STS/ACC TVT Registry." Jacc. Cardiovascular Interventions 11, no. 17 (September 2018): 1746-1756.  Full Text
    • Kochar, A, Li, Z, Harrison, JK, Hughes, GC, Thourani, VH, Mack, MJ, Matsouaka, RA, Cohen, DJ, Peterson, ED, Jones, WS, and Vemulapalli, S. "Stroke and Cardiovascular Outcomes in Patients With Carotid Disease Undergoing Transcatheter Aortic Valve Replacement." Circulation. Cardiovascular Interventions 11, no. 6 (June 2018): e006322-null.  Full Text
    • Puskas, JD, Gerdisch, M, Nichols, D, Fermin, L, Rhenman, B, Kapoor, D, Copeland, J, Quinn, R, Hughes, GC, Azar, H, McGrath, M, Wait, M, Kong, B, Martin, T, Douville, EC, Meyer, S, Ye, J, Jamieson, WRE, Landvater, L, Hagberg, R, Trotter, T, Armitage, J, Askew, J, Accola, K, Levy, P, Duncan, D, Yanagawa, B, Ely, J, Graeve, A, and PROACT Investigators, . "Anticoagulation and Antiplatelet Strategies After On-X Mechanical Aortic Valve Replacement." Journal of the American College of Cardiology 71, no. 24 (June 2018): 2717-2726.  Full Text
    • Hughes, GC. "Classic hybrid arch debranching (type I hybrid arch repair) without circulatory arrest." Annals of Cardiothoracic Surgery 7, no. 3 (May 2018): 443-450.  Full Text
    • Klinger, RY, James, OG, Borges-Neto, S, Bisanar, T, Li, Y-J, Qi, W, Berger, M, Terrando, N, Newman, MF, Doraiswamy, PM, Mathew, JP, Alzheimer’s Disease Neuroimaging Initiative (ADNI) Study Group, , and Neurologic Outcomes Research Group (NORG), . "18F-florbetapir Positron Emission Tomography-determined Cerebral β-Amyloid Deposition and Neurocognitive Performance after Cardiac Surgery." Anesthesiology 128, no. 4 (April 2018): 728-744.  Full Text
    • Gleason, TG, Schindler, JT, Hagberg, RC, Deeb, GM, Adams, DH, Conte, JV, Zorn, GL, Hughes, GC, Guo, J, Popma, JJ, and Reardon, MJ. "Subclavian/Axillary Access for Self-Expanding Transcatheter Aortic Valve Replacement Renders Equivalent Outcomes as Transfemoral." The Annals of Thoracic Surgery 105, no. 2 (February 2018): 477-483.  Full Text
    • Lee, TC, Kon, Z, Cheema, FH, Grau-Sepulveda, MV, Englum, B, Kim, S, Chaudhuri, PS, Thourani, VH, Ailawadi, G, Hughes, GC, Williams, ML, Brennan, JM, Svensson, L, and Gammie, JS. "Contemporary management and outcomes of acute type A aortic dissection: An analysis of the STS adult cardiac surgery database." Journal of Cardiac Surgery 33, no. 1 (January 4, 2018): 7-18.  Full Text
    • Keeling, WB, Tian, DH, Leshnower, BG, Numata, S, Hughes, GC, Matalanis, G, Okita, Y, Yan, TD, Kouchoukos, N, Chen, EP, and IAASSG Investigators, . "Safety of Moderate Hypothermia With Antegrade Cerebral Perfusion in Total Aortic Arch Replacement." The Annals of Thoracic Surgery 105, no. 1 (January 2018): 54-61.  Full Text
    • Plichta, RP, and Hughes, GC. "Thoracic endovascular aortic repair for the ascending aorta: experience and pitfalls." Journal of Visualized Surgery 4 (January 2018): 92-null. (Review)  Full Text
    • Wang, A, Ganapathi, AM, Wang, A, and Hughes, GC. "The Modified Ross Procedure with Prosthetic Graft Wrap Does Not Prevent Autograft Failure." The Journal of Heart Valve Disease 26, no. 6 (November 2017): 735-737.
    • Fanaroff, AC, Manandhar, P, Holmes, DR, Cohen, DJ, Harrison, JK, Hughes, GC, Thourani, VH, Mack, MJ, Sherwood, MW, Jones, WS, and Vemulapalli, S. "Peripheral Artery Disease and Transcatheter Aortic Valve Replacement Outcomes: A Report From the Society of Thoracic Surgeons/American College of Cardiology Transcatheter Therapy Registry." Circulation. Cardiovascular Interventions 10, no. 10 (October 2017).  Full Text
    • Karhausen, JA, Smeltz, AM, Akushevich, I, Cooter, M, Podgoreanu, MV, Stafford-Smith, M, Martinelli, SM, Fontes, ML, and Kertai, MD. "Platelet Counts and Postoperative Stroke After Coronary Artery Bypass Grafting Surgery." Anesthesia and Analgesia 125, no. 4 (October 2017): 1129-1139.  Full Text  Open Access Copy
    • Englum, BR, He, X, Gulack, BC, Ganapathi, AM, Mathew, JP, Brennan, JM, Reece, TB, Keeling, WB, Leshnower, BG, Chen, EP, Jacobs, JP, Thourani, VH, and Hughes, GC. "Hypothermia and cerebral protection strategies in aortic arch surgery: a comparative effectiveness analysis from the STS Adult Cardiac Surgery Database." European Journal of Cardio Thoracic Surgery : Official Journal of the European Association for Cardio Thoracic Surgery 52, no. 3 (September 2017): 492-498.  Full Text
    • Iribarne, A, Keenan, J, Benrashid, E, Wang, H, Meza, JM, Ganapathi, A, Gaca, JG, Kim, HW, Hurwitz, LM, and Hughes, GC. "Imaging Surveillance After Proximal Aortic Operations: Is it Necessary?." The Annals of Thoracic Surgery 103, no. 3 (March 2017): 734-741.  Full Text
    • Popma, JJ, Reardon, MJ, Khabbaz, K, Harrison, JK, Hughes, GC, Kodali, S, George, I, Deeb, GM, Chetcuti, S, Kipperman, R, Brown, J, Qiao, H, Slater, J, and Williams, MR. "Early Clinical Outcomes After Transcatheter Aortic Valve Replacement Using a Novel Self-Expanding Bioprosthesis in Patients With Severe Aortic Stenosis Who Are Suboptimal for Surgery: Results of the Evolut R U.S. Study." Jacc. Cardiovascular Interventions 10, no. 3 (February 2017): 268-275.  Full Text
    • Harrison, JK, Hughes, GC, Reardon, MJ, Stoler, R, Grayburn, P, Hebeler, R, Liu, D, Chang, Y, Popma, JJ, and CoreValve US Clinical Investigators, . "Balloon Post-Dilation Following Implantation of a Self-Expanding Transcatheter Aortic Valve Bioprosthesis." Jacc. Cardiovascular Interventions 10, no. 2 (January 2017): 168-175.  Full Text
    • Kertai, MD, Cheruku, S, Qi, W, Li, Y-J, Hughes, GC, Mathew, JP, and Karhausen, JA. "Mast cell activation and arterial hypotension during proximal aortic repair requiring hypothermic circulatory arrest." The Journal of thoracic and cardiovascular surgery 153, no. 1 (January 2017): 68-76.e2.  Full Text  Open Access Copy
    • Kiefer, TL, Vavalle, J, Hurwitz, LM, Hughes, GC, and Harrison, JK. "Resolution of severe hemolysis and paravalvular aortic regurgitation employing an Amplatzer Vascular Plug 4: the importance of detailed pre-procedural planning using CT angiography." Cardiovascular intervention and therapeutics 32, no. 1 (January 2017): 48-52.  Full Text
    • Keenan, JE, Benrashid, E, Kale, E, Nicoara, A, Husain, AM, and Hughes, GC. "Neurophysiological Intraoperative Monitoring During Aortic Arch Surgery." Seminars in Cardiothoracic and Vascular Anesthesia 20, no. 4 (December 2016): 273-282. (Review)  Full Text
    • Keenan, JE, Wang, H, Gulack, BC, Ganapathi, AM, Andersen, ND, Englum, BR, Krishnamurthy, Y, Levy, JH, Welsby, IJ, and Hughes, GC. "Does moderate hypothermia really carry less bleeding risk than deep hypothermia for circulatory arrest? A propensity-matched comparison in hemiarch replacement." The Journal of Thoracic and Cardiovascular Surgery 152, no. 6 (December 2016): 1559-1569.e2.  Full Text
    • Nauta, FJH, Tolenaar, JL, Patel, HJ, Appoo, JJ, Tsai, TT, Desai, ND, Montgomery, DG, Mussa, FF, Upchurch, GR, Fattori, R, Hughes, GC, Nienaber, CA, Isselbacher, EM, Eagle, KA, Trimarchi, S, and International Registry of Acute Aortic Dissection (IRAD) Investigators, . "Impact of Retrograde Arch Extension in Acute Type B Aortic Dissection on Management and Outcomes." The Annals of Thoracic Surgery 102, no. 6 (December 2016): 2036-2043.  Full Text
    • Benrashid, E, Wang, H, Andersen, ND, Keenan, JE, McCann, RL, and Hughes, GC. "Complementary roles of open and hybrid approaches to thoracoabdominal aortic aneurysm repair." Journal of vascular surgery 64, no. 5 (November 2016): 1228-1238.  Full Text
    • Gleason, T, Popma, J, Reardon, M, Schindler, J, Hagberg, R, Deeb, GM, Adams, D, Conte, J, Zorn, T, and Hughes, GC. "TCT-372 Subclavian Access for Self-Expanding Transcatheter Aortic Valve Replacement Renders Equivalent Outcomes as Transfemoral." Journal of the American College of Cardiology 68, no. 18S (November 2016): B152-.  Full Text
    • Popma, J, Dibu, G, Hughes, GC, Kodali, S, George, I, Oh, J, Slater, J, and Williams, M. "TCT-37 Transcatheter Aortic Valve Replacement with a Repositionable Self-expanding Bioprosthesis in Patients With Severe Aortic Stenosis at High Risk for Surgery: One-Year Results from the Evolut R US Pivotal Study." Journal of the American College of Cardiology 68, no. 18S (November 2016): B16-.  Full Text
    • Reardon, MJ, Kleiman, NS, Adams, DH, Yakubov, SJ, Coselli, JS, Deeb, GM, O'Hair, D, Gleason, TG, Lee, JS, Hermiller, JB, Chetcuti, S, Heiser, J, Merhi, W, Zorn, GL, Tadros, P, Robinson, N, Petrossian, G, Hughes, GC, Harrison, JK, Maini, B, Mumtaz, M, Conte, JV, Resar, JR, Aharonian, V, Pfeffer, T, Oh, JK, Huang, J, and Popma, JJ. "Outcomes in the Randomized CoreValve US Pivotal High Risk Trial in Patients With a Society of Thoracic Surgeons Risk Score of 7% or Less." Jama Cardiology 1, no. 8 (November 2016): 945-949.  Full Text
    • Sherwood, M, Xiang, Q, Matsouaka, R, Hughes, GC, Vemulapalli, S, Vora, A, Peterson, E, and Rao, S. "TCT-78 Incidence and Outcomes of Vascular Complications and Bleeding Events in Patients undergoing TAVR in contemporary U.S. practice: Insights from the STS/ACC TVT Registry®." Journal of the American College of Cardiology 68, no. 18S (November 2016): B32-.  Full Text
    • Andersen, ND, and Hughes, GC. "Concomitant replacement of the ascending aorta is free-for some." The Journal of Thoracic and Cardiovascular Surgery 152, no. 3 (September 2016): 799-800.  Full Text
    • Gleason, TG, Schindler, JT, Adams, DH, Reardon, MJ, Kleiman, NS, Caplan, LR, Conte, JV, Deeb, GM, Hughes, GC, Chenoweth, S, and Popma, JJ. "The risk and extent of neurologic events are equivalent for high-risk patients treated with transcatheter or surgical aortic valve replacement." The Journal of Thoracic and Cardiovascular Surgery 152, no. 1 (July 2016): 85-96.  Full Text
    • Deeb, GM, Reardon, MJ, Chetcuti, S, Patel, HJ, Grossman, PM, Yakubov, SJ, Kleiman, NS, Coselli, JS, Gleason, TG, Lee, JS, Hermiller, JB, Heiser, J, Merhi, W, Zorn, GL, Tadros, P, Robinson, N, Petrossian, G, Hughes, GC, Harrison, JK, Maini, B, Mumtaz, M, Conte, J, Resar, J, Aharonian, V, Pfeffer, T, Oh, JK, Qiao, H, Adams, DH, Popma, JJ, and CoreValve US Clinical Investigators, . "3-Year Outcomes in High-Risk Patients Who Underwent Surgical or Transcatheter Aortic Valve Replacement." Journal of the American College of Cardiology 67, no. 22 (June 2016): 2565-2574.  Full Text
    • Hughes, GC. "Invited Commentary." The Annals of thoracic surgery 101, no. 6 (June 2016): 2235-2236.  Full Text
    • Andersen, ND, Benrashid, E, Ross, AK, Pickett, LC, Smith, PK, Daneshmand, MA, Schroder, JN, Gaca, JG, and Hughes, GC. "The utility of the aortic dissection team: outcomes and insights after a decade of experience." Annals of cardiothoracic surgery 5, no. 3 (May 2016): 194-201.  Full Text
    • Benrashid, E, Wang, H, Keenan, JE, Andersen, ND, Meza, JM, McCann, RL, and Hughes, GC. "Evolving practice pattern changes and outcomes in the era of hybrid aortic arch repair." Journal of Vascular Surgery 63, no. 2 (February 2016): 323-331.  Full Text
    • Hanna, JM, Keenan, JE, Wang, H, Andersen, ND, Gaca, JG, Lombard, FW, Welsby, IJ, and Hughes, GC. "Use of human fibrinogen concentrate during proximal aortic reconstruction with deep hypothermic circulatory arrest." The Journal of thoracic and cardiovascular surgery 151, no. 2 (February 2016): 376-382.  Full Text
    • Keenan, JE, Wang, H, Ganapathi, AM, Englum, BR, Kale, E, Mathew, JP, Husain, AM, and Hughes, GC. "Electroencephalography During Hemiarch Replacement With Moderate Hypothermic Circulatory Arrest." The Annals of Thoracic Surgery 101, no. 2 (February 2016): 631-637.  Full Text
    • Schechter, MA, Shah, AA, Englum, BR, Williams, JB, Ganapathi, AM, Davies, JD, Welsby, IJ, and Hughes, GC. "Prolonged postoperative respiratory support after proximal thoracic aortic surgery: Is deep hypothermic circulatory arrest a risk factor?." Journal of Critical Care 31, no. 1 (February 2016): 125-129.  Full Text
    • Conte, JV, Gleason, TG, Resar, JR, Adams, DH, Deeb, GM, Popma, JJ, Hughes, GC, Zorn, GL, and Reardon, MJ. "Transcatheter or Surgical Aortic Valve Replacement in Patients With Prior Coronary Artery Bypass Grafting." The Annals of Thoracic Surgery 101, no. 1 (January 2016): 72-79.  Full Text
    • Englum, BR, Ganapathi, AM, Schechter, MA, Harrison, JK, Glower, DD, and Hughes, GC. "Changes in Risk Profile and Outcomes of Patients Undergoing Surgical Aortic Valve Replacement From the Pre- to Post-Transcatheter Aortic Valve Replacement Eras." The Annals of Thoracic Surgery 101, no. 1 (January 2016): 110-117.  Full Text
    • Illig, KA, Ohki, T, Hughes, GC, Kato, M, Shimizu, H, Patel, HJ, Shahriari, A, Mehta, S, and Zenith TX2 Low Profile study investigators, . "One-year outcomes from the international multicenter study of the Zenith Alpha Thoracic Endovascular Graft for thoracic endovascular repair." Journal of vascular surgery 62, no. 6 (December 2015): 1485-94.e2.  Full Text
    • Davis, RP, Andersen, ND, Ganapathi, AM, DiBernardo, LR, and Hughes, GC. "Repair of Bicuspid Aortic Valve Syndrome with Anomalous Right Coronary Artery in Osteogenesis Imperfecta." The Journal of heart valve disease 24, no. 6 (November 2015): 666-668.
    • Klinger, RY, Thunberg, CA, White, WD, Fontes, M, Waldron, NH, Piccini, JP, Hughes, GC, Podgoreanu, MV, Stafford-Smith, M, Newman, MF, and Mathew, JP. "Intraoperative Magnesium Administration Does Not Reduce Postoperative Atrial Fibrillation After Cardiac Surgery." Anesthesia and Analgesia 121, no. 4 (October 2015): 861-867.  Full Text
    • Bavaria, JE, Brinkman, WT, Hughes, GC, Khoynezhad, A, Szeto, WY, Azizzadeh, A, Lee, WA, and White, RA. "Outcomes of Thoracic Endovascular Aortic Repair in Acute Type B Aortic Dissection: Results From the Valiant United States Investigational Device Exemption Study." The Annals of thoracic surgery 100, no. 3 (September 2015): 802-808.  Full Text
    • Yakubov, SJ, Adams, DH, Watson, DR, Reardon, MJ, Kleiman, NS, Heimansohn, D, Hermiller, J, Hughes, GC, Harrison, JK, Coselli, J, Diez, J, Schreiber, T, Gleason, TG, Conte, J, Deeb, GM, Huang, J, Oh, J, Byrne, T, Caskey, M, Popma, JJ, and CoreValve United States Clinical Investigators, . "2-Year Outcomes After Iliofemoral Self-Expanding Transcatheter Aortic Valve Replacement in Patients With Severe Aortic Stenosis Deemed Extreme Risk for Surgery." Journal of the American College of Cardiology 66, no. 12 (September 2015): 1327-1334.  Full Text
    • Shah, AA, Gregory, SG, Krupp, D, Feng, S, Dorogi, A, Haynes, C, Grass, E, Lin, SS, Hauser, ER, Kraus, WE, Shah, SH, and Hughes, GC. "Epigenetic profiling identifies novel genes for ascending aortic aneurysm formation with bicuspid aortic valves." The heart surgery forum 18, no. 4 (August 30, 2015): E134-E139.  Full Text
    • Ganapathi, AM, Englum, BR, Keenan, JE, Schechter, MA, Wang, H, Smith, PK, Glower, DD, and Hughes, GC. "Long-Term Survival After Bovine Pericardial Versus Porcine Stented Bioprosthetic Aortic Valve Replacement: Does Valve Choice Matter?." The Annals of thoracic surgery 100, no. 2 (August 2015): 550-559.  Full Text
    • Keenan, JE, Vavalle, JP, Ganapathi, AM, Wang, H, Harrison, JK, Wang, A, and Hughes, GC. "Factor VIIa for Annulus Rupture After Transcatheter Aortic Valve Replacement." The Annals of thoracic surgery 100, no. 1 (July 2015): 313-315.  Full Text
    • Klein, MR, Sundh, F, Simlund, J, Harrison, JK, Jackson, KP, Hughes, GC, Wagner, GS, Risum, N, Søgaard, P, Strauss, DG, and Kisslo, J. "Immediate mechanical effects of acute left bundle branch block by speckle tracked strain." Journal of electrocardiology 48, no. 4 (July 2015): 643-651.  Full Text
    • Reardon, MJ, Adams, DH, Kleiman, NS, Yakubov, SJ, Coselli, JS, Deeb, GM, Gleason, TG, Lee, JS, Hermiller, JB, Chetcuti, S, Heiser, J, Merhi, W, Zorn, GL, Tadros, P, Robinson, N, Petrossian, G, Hughes, GC, Harrison, JK, Maini, B, Mumtaz, M, Conte, JV, Resar, JR, Aharonian, V, Pfeffer, T, Oh, JK, Qiao, H, and Popma, JJ. "2-Year Outcomes in Patients Undergoing Surgical or Self-Expanding Transcatheter Aortic Valve Replacement." Journal of the American College of Cardiology 66, no. 2 (July 2015): 113-121.  Full Text
    • Wang, H, Hanna, JM, Ganapathi, A, Keenan, JE, Hurwitz, LM, Vavalle, JP, Kiefer, TL, Wang, A, Harrison, JK, and Hughes, GC. "Comparison of aortic annulus size by transesophageal echocardiography and computed tomography angiography with direct surgical measurement." The American journal of cardiology 115, no. 11 (June 2015): 1568-1573.  Full Text
    • Williams, JA, Hanna, JM, Shah, AA, Andersen, ND, McDonald, MT, Jiang, Y-H, Wechsler, SB, Zomorodi, A, McCann, RL, and Hughes, GC. "Adult surgical experience with Loeys-Dietz syndrome." The Annals of thoracic surgery 99, no. 4 (April 2015): 1275-1281.  Full Text
    • Sundh, F, Simlund, J, Harrison, JK, Hughes, GC, Vavalle, J, Maynard, C, Strauss, DG, Wagner, GS, and Ugander, M. "Incidence of strict versus nonstrict left bundle branch block after transcatheter aortic valve replacement." American heart journal 169, no. 3 (March 2015): 438-444.  Full Text
    • Walker, WL, Boll, DT, Bueno, JM, Kiefer, TL, Vavalle, JP, Gaca, JG, Harrison, JK, Hughes, GC, Wang, A, and Hurwitz, LM. "Assessment of single-bolus contrast administration technique using hybrid dual-source ECG-gated thoracic and dual-source non-ECG-gated high-pitch abdominopelvic CT acquisitions for procedural planning before transcatheter aortic valve replacement." Journal of computer assisted tomography 39, no. 2 (March 2015): 207-212.  Full Text
    • Hughes, GC. "Management of acute type B aortic dissection; ADSORB trial." The Journal of thoracic and cardiovascular surgery 149, no. 2 Suppl (February 2015): S158-S162. (Review)  Full Text
    • Di Eusanio, M, Trimarchi, S, Peterson, MD, Myrmel, T, Hughes, GC, Korach, A, Sundt, TM, Di Bartolomeo, R, Greason, K, Khoynezhad, A, Appoo, JJ, Folesani, G, De Vincentiis, C, Montgomery, DG, Isselbacher, EM, Eagle, KA, Nienaber, CA, and Patel, HJ. "Root replacement surgery versus more conservative management during type A acute aortic dissection repair." The Annals of Thoracic Surgery 98, no. 6 (December 2014): 2078-2084.  Full Text
    • Englum, BR, Pavlisko, EN, Mack, MC, Ganapathi, AM, Schechter, MA, Hanna, JM, and Hughes, GC. "Pseudoaneurysm formation after medtronic freestyle porcine aortic bioprosthesis implantation: a word of caution." The Annals of thoracic surgery 98, no. 6 (December 2014): 2061-2067.  Full Text
    • Ganapathi, AM, Hanna, JM, Schechter, MA, Englum, BR, Castleberry, AW, Gaca, JG, and Hughes, GC. "Antegrade versus retrograde cerebral perfusion for hemiarch replacement with deep hypothermic circulatory arrest: does it matter? A propensity-matched analysis." The Journal of Thoracic and Cardiovascular Surgery 148, no. 6 (December 2014): 2896-2902.  Full Text
    • Hughes, GC, Ganapathi, AM, Keenan, JE, Englum, BR, Hanna, JM, Schechter, MA, Wang, H, and McCann, RL. "Thoracic endovascular aortic repair for chronic DeBakey IIIb aortic dissection." The Annals of thoracic surgery 98, no. 6 (December 2014): 2092-2098.  Full Text
    • Reardon, MJ, Adams, DH, Coselli, JS, Deeb, GM, Kleiman, NS, Chetcuti, S, Yakubov, SJ, Heimansohn, D, Hermiller, J, Hughes, GC, Harrison, JK, Khabbaz, K, Tadros, P, Zorn, GL, Merhi, W, Heiser, J, Petrossian, G, Robinson, N, Maini, B, Mumtaz, M, Lee, JS, Gleason, TG, Resar, J, Conte, J, Watson, D, Chenoweth, S, Popma, JJ, and CoreValve US Clinical Investigators, . "Self-expanding transcatheter aortic valve replacement using alternative access sites in symptomatic patients with severe aortic stenosis deemed extreme risk of surgery." The Journal of thoracic and cardiovascular surgery 148, no. 6 (December 2014): 2869-76.e1-7-.  Full Text
    • Andersen, ND, Hanna, JM, Ganapathi, AM, Bhattacharya, SD, Williams, JB, Gaca, JG, McCann, RL, and Hughes, GC. "Insurance status predicts acuity of thoracic aortic operations." The Journal of thoracic and cardiovascular surgery 148, no. 5 (November 2014): 2082-2086.  Full Text
    • Dean, JH, Woznicki, EM, O'Gara, P, Montgomery, DG, Trimarchi, S, Myrmel, T, Pyeritz, RE, Harris, KM, Suzuki, T, Braverman, AC, Hughes, GC, Kline-Rogers, E, Nienaber, CA, Isselbacher, EM, Eagle, KA, and Bossone, E. "Cocaine-related aortic dissection: lessons from the International Registry of Acute Aortic Dissection." The American journal of medicine 127, no. 9 (September 2014): 878-885.  Full Text
    • Vavalle, JP, Phillips, HR, Holleran, SA, Wang, A, O'Connor, CM, Smith, PK, Hughes, GC, Harrison, JK, and Patel, MR. "Analysis of geographic variations in the diagnosis and treatment of patients with aortic stenosis in North Carolina." The American journal of cardiology 113, no. 11 (June 2014): 1874-1878.  Full Text
    • Adams, DH, Popma, JJ, Reardon, MJ, Yakubov, SJ, Coselli, JS, Deeb, GM, Gleason, TG, Buchbinder, M, Hermiller, J, Kleiman, NS, Chetcuti, S, Heiser, J, Merhi, W, Zorn, G, Tadros, P, Robinson, N, Petrossian, G, Hughes, GC, Harrison, JK, Conte, J, Maini, B, Mumtaz, M, Chenoweth, S, Oh, JK, and U.S. CoreValve Clinical Investigators, . "Transcatheter aortic-valve replacement with a self-expanding prosthesis." The New England Journal of Medicine 370, no. 19 (May 2014): 1790-1798.  Full Text
    • Andersen, ND, Brennan, JM, Zhao, Y, Williams, JB, Williams, ML, Smith, PK, Scarborough, JE, and Hughes, GC. "Insurance status is associated with acuity of presentation and outcomes for thoracic aortic operations." Circulation. Cardiovascular Quality and Outcomes 7, no. 3 (May 2014): 398-406.  Full Text
    • Andersen, ND, Ganapathi, AM, Hanna, JM, Williams, JB, Gaca, JG, and Hughes, GC. "Outcomes of acute type a dissection repair before and after implementation of a multidisciplinary thoracic aortic surgery program." Journal of the American College of Cardiology 63, no. 17 (May 2014): 1796-1803.  Full Text
    • Andersen, ND, Keenan, JE, Ganapathi, AM, Gaca, JG, McCann, RL, and Hughes, GC. "Current management and outcome of chronic type B aortic dissection: results with open and endovascular repair since the advent of thoracic endografting." Annals of Cardiothoracic Surgery 3, no. 3 (May 2014): 264-274.  Full Text
    • Popma, JJ, Adams, DH, Reardon, MJ, Yakubov, SJ, Kleiman, NS, Heimansohn, D, Hermiller, J, Hughes, GC, Harrison, JK, Coselli, J, Diez, J, Kafi, A, Schreiber, T, Gleason, TG, Conte, J, Buchbinder, M, Deeb, GM, Carabello, B, Serruys, PW, Chenoweth, S, Oh, JK, and CoreValve United States Clinical Investigators, . "Transcatheter aortic valve replacement using a self-expanding bioprosthesis in patients with severe aortic stenosis at extreme risk for surgery." Journal of the American College of Cardiology 63, no. 19 (May 2014): 1972-1981.  Full Text
    • Vavalle, JP, Kiefer, TL, Milano, CA, Harrison, JK, and Hughes, GC. "Transcatheter aortic valve replacement performed via left ventricular assist device inflow cannula." Circulation. Heart Failure 7, no. 3 (May 2014): 544-546.  Full Text
    • Ganapathi, AM, Andersen, ND, Hanna, JM, Gaca, JG, McCann, RL, and Hughes, GC. "Comparison of attachment site endoleak rates in Dacron versus native aorta landing zones after thoracic endovascular aortic repair." J Vasc Surg 59, no. 4 (April 2014): 921-929.  Full Text  Link to Item
    • Puskas, J, Gerdisch, M, Nichols, D, Quinn, R, Anderson, C, Rhenman, B, Fermin, L, McGrath, M, Kong, B, Hughes, C, Sethi, G, Wait, M, Martin, T, Graeve, A, and PROACT Investigators, . "Reduced anticoagulation after mechanical aortic valve replacement: interim results from the prospective randomized on-X valve anticoagulation clinical trial randomized Food and Drug Administration investigational device exemption trial." The Journal of Thoracic and Cardiovascular Surgery 147, no. 4 (April 2014): 1202-1210.  Full Text
    • Yan, TD, Tian, DH, LeMaire, SA, Hughes, GC, Chen, EP, Misfeld, M, Griepp, RB, Kazui, T, Bannon, PG, Coselli, JS, Elefteriades, JA, Kouchoukos, NT, Underwood, MJ, Mathew, JP, Mohr, F-W, Oo, A, Sundt, TM, Bavaria, JE, Di Bartolomeo, R, Di Eusanio, M, Trimarchi, S, and International Aortic Arch Surgery Study Group, . "Standardizing clinical end points in aortic arch surgery: a consensus statement from the International Aortic Arch Surgery Study Group." Circulation 129, no. 15 (April 2014): 1610-1616.  Full Text
    • Glower, DD, Desai, BS, Hughes, GC, Milano, CA, and Gaca, JG. "Aortic valve replacement via right minithoracotomy versus median sternotomy: a propensity score analysis." Innovations (Philadelphia, Pa.) 9, no. 2 (March 2014): 75-81.  Full Text
    • James, ML, Andersen, ND, Swaminathan, M, Phillips-Bute, B, Hanna, JM, Smigla, GR, Barfield, ME, Bhattacharya, SD, Williams, JB, Gaca, JG, Husain, AM, and Hughes, GC. "Predictors of electrocerebral inactivity with deep hypothermia." The Journal of Thoracic and Cardiovascular Surgery 147, no. 3 (March 2014): 1002-1007.  Full Text
    • Ganapathi, AM, Englum, BR, Hanna, JM, Schechter, MA, Gaca, JG, Hurwitz, LM, and Hughes, GC. "Frailty and risk in proximal aortic surgery." The Journal of Thoracic and Cardiovascular Surgery 147, no. 1 (January 2014): 186-191.e1.  Full Text
    • Ganapathi, AM, Englum, BR, Schechter, MA, Vavalle, JP, Harrison, JK, McCann, RL, and Hughes, GC. "Role of cardiac evaluation before thoracic endovascular aortic repair." Journal of Vascular Surgery 60, no. 5 (January 1, 2014): 1196-1203.  Full Text
    • Hanna, JM, Andersen, ND, Ganapathi, AM, McCann, RL, and Hughes, GC. "Five-year results for endovascular repair of acute complicated type B aortic dissection." J Vasc Surg 59, no. 1 (January 2014): 96-106.  Full Text  Link to Item
    • Kiefer, TL, Hughes, GC, Johnson, JC, and Harrison, JK. "Aortic subannular left ventricular aneurysm: a rare and surgically correctable cause of angina." Ann Thorac Surg 97, no. 1 (January 2014): 313-315.  Full Text  Link to Item
    • Yan, TD, Tian, DH, LeMaire, SA, Misfeld, M, Elefteriades, JA, Chen, EP, Hughes, GC, Kazui, T, Griepp, RB, Kouchoukos, NT, Bannon, PG, Underwood, MJ, Mohr, F-W, Oo, A, Sundt, TM, Bavaria, JE, Di Bartolomeo, R, Di Eusanio, M, Roselli, EE, Beyersdorf, F, Carrel, TP, Corvera, JS, Della Corte, A, Ehrlich, M, Hoffman, A, Jakob, H, Matalanis, G, Numata, S, Patel, HJ, Pochettino, A, Safi, HJ, Estrera, A, Perreas, KG, Sinatra, R, Trimarchi, S, Sun, L-Z, Tabata, M, Wang, C, Haverich, A, Shrestha, M, Okita, Y, and Coselli, J. "The ARCH Projects: design and rationale (IAASSG 001)." European Journal of Cardio Thoracic Surgery : Official Journal of the European Association for Cardio Thoracic Surgery 45, no. 1 (January 2014): 10-16.  Full Text
    • Yan, TD, Tian, DH, LeMaire, SA, Misfeld, M, Elefteriades, JA, Chen, EP, Hughes, GC, Kazui, T, Griepp, RB, Kouchoukos, NT, Bannon, PG, Underwood, MJ, Mohr, FW, Oo, A, Sundt, TM, Bavaria, JE, Di Bartolomeo, R, Di Eusanio, M, Roselli, EE, Beyersdorf, F, Carrel, TP, Corvera, JS, Della Corte, A, Ehrlich, M, Hoffman, A, Jakob, H, Matalanis, G, Numata, S, Patel, HJ, Pochettino, A, Safi, HJ, Estrera, A, Perreas, KG, Sinatra, R, Trimarchi, S, Sun, LZ, Tabata, M, Wang, C, Haverich, A, and Shrestha, M et al. "The ARCH projects: Design and rationale (IAASSG 001)." European Journal of Cardio-thoracic Surgery 45, no. 1 (January 1, 2014): 10-16.  Full Text
    • Gaca, JG, Clare, RM, Rankin, JS, Daneshmand, MA, Milano, CA, Hughes, GC, Wolfe, WG, Glower, DD, and Smith, PK. "Risk-adjusted survival after tissue versus mechanical aortic valve replacement: a 23-year assessment." The Journal of heart valve disease 22, no. 6 (November 2013): 810-816.
    • Ong, DS, Aertker, RA, Clark, AN, Kiefer, T, Hughes, GC, Harrison, JK, and Bashore, TM. "Radiation-associated valvular heart disease." The Journal of Heart Valve Disease 22, no. 6 (November 2013): 883-892. (Review)
    • Halim, SA, Kiefer, TL, Hughes, GC, Hurwitz, LM, and Harrison, JK. "Transcatheter aortic valve replacement: an update." Curr Cardiol Rep 15, no. 6 (June 2013): 367-. (Review)  Full Text  Link to Item
    • Hanna, JM, Andersen, ND, Aziz, H, Shah, AA, McCann, RL, and Hughes, GC. "Results with selective preoperative lumbar drain placement for thoracic endovascular aortic repair." Ann Thorac Surg 95, no. 6 (June 2013): 1968-1974.  Full Text  Link to Item
    • Ikonomidis, JS, Ivey, CR, Wheeler, JB, Akerman, AW, Rice, A, Patel, RK, Stroud, RE, Shah, AA, Hughes, CG, Ferrari, G, Mukherjee, R, and Jones, JA. "Plasma biomarkers for distinguishing etiologic subtypes of thoracic aortic aneurysm disease." The Journal of Thoracic and Cardiovascular Surgery 145, no. 5 (May 2013): 1326-1333.  Full Text
    • Shah, AA, Craig, DM, Andersen, ND, Williams, JB, Bhattacharya, SD, Shah, SH, McCann, RL, and Hughes, GC. "Risk factors for 1-year mortality after thoracic endovascular aortic repair." The Journal of thoracic and cardiovascular surgery 145, no. 5 (May 2013): 1242-1247.  Full Text
    • Andersen, ND, Barfield, ME, Hanna, JM, Shah, AA, Shortell, CK, McCann, RL, and Hughes, GC. "Intrathoracic subclavian artery aneurysm repair in the thoracic endovascular aortic repair era." J Vasc Surg 57, no. 4 (April 2013): 915-925.  Full Text  Link to Item
    • Andersen, ND, Williams, JB, Hanna, JM, Shah, AA, McCann, RL, and Hughes, GC. "Results with an algorithmic approach to hybrid repair of the aortic arch." Journal of Vascular Surgery 57, no. 3 (March 2013): 655-667.  Full Text
    • Englum, BR, Andersen, ND, Husain, AM, Mathew, JP, and Hughes, GC. "Degree of hypothermia in aortic arch surgery - optimal temperature for cerebral and spinal protection: deep hypothermia remains the gold standard in the absence of randomized data." Annals of Cardiothoracic Surgery 2, no. 2 (March 2013): 184-193.  Full Text
    • Hughes, GC, Andersen, ND, and McCann, RL. "Management of acute type B aortic dissection." J Thorac Cardiovasc Surg 145, no. 3 Suppl (March 2013): S202-S207. (Review)  Full Text  Link to Item
    • Atkins, BZ, Hashmi, ZA, Ganapathi, AM, Harrison, JK, Hughes, GC, Rogers, JG, and Milano, CA. "Surgical correction of aortic valve insufficiency after left ventricular assist device implantation." Journal of Thoracic and Cardiovascular Surgery 146, no. 5 (2013): 1247-1252.  Full Text
    • Bossone, E, Pyeritz, RE, O'Gara, P, Harris, KM, Braverman, AC, Pape, L, Russo, MJ, Hughes, GC, Tsai, TT, Montgomery, DG, Nienaber, CA, Isselbacher, EM, and Eagle, KA. "Acute aortic dissection in blacks: Insights from the international registry of acute aortic dissection." American Journal of Medicine 126, no. 10 (2013): 909-915.  Full Text
    • Ganapathi, AM, Andersen, ND, Prastein, DJ, Hashmi, ZA, Rogers, JG, Milano, CA, McCann, RL, and Hughes, GC. "Endovascular stent grafting of a left ventricular assist device outflow graft pseudoaneurysm." Circ Heart Fail 6, no. 1 (January 2013): e16-e18.  Full Text  Link to Item
    • Hughes, GC, Zhao, Y, Rankin, JS, Scarborough, JE, O'Brien, S, Bavaria, JE, Wolfe, WG, Gaca, JG, Gammie, JS, Shahian, DM, and Smith, PK. "Effects of institutional volumes on operative outcomes for aortic root replacement in North America." The Journal of Thoracic and Cardiovascular Surgery 145, no. 1 (January 2013): 166-170.  Full Text
    • Shah, AA, Mccann, RL, and Hughes, GC. "Conformable Gore® TAG® Thoracic Endoprosthesis for the treatment of thoracic aortic aneurysms." Interventional Cardiology (London) 5, no. 3 (2013): 267-274.  Full Text
    • Nelson, JA, Vavalle, J, Halim, S, Hughes, GC, Wang, A, Koweek, L, Glower, D, Gaca, J, Alexander, J, and Harrison, JK. "Who is Being Referred for TAVR?: Patterns of Referral for TAVR at a Single Academic Medical Center." CIRCULATION 126, no. 21 (November 20, 2012).  Link to Item
    • Shah, AA, Barfield, ME, Andersen, ND, Williams, JB, Shah, JA, Hanna, JM, McCann, RL, and Hughes, GC. "Results of thoracic endovascular aortic repair 6 years after United States Food and Drug Administration approval." The Annals of thoracic surgery 94, no. 5 (November 2012): 1394-1399.  Full Text
    • Steinberg, BA, Harrison, JK, Frazier-Mills, C, Hughes, GC, and Piccini, JP. "Cardiac conduction system disease after transcatheter aortic valve replacement." Am Heart J 164, no. 5 (November 2012): 664-671. (Review)  Full Text  Link to Item
    • Williams, JB, Peterson, ED, Zhao, Y, O'Brien, SM, Andersen, ND, Miller, DC, Chen, EP, and Hughes, GC. "Contemporary results for proximal aortic replacement in North America." Journal of the American College of Cardiology 60, no. 13 (September 5, 2012): 1156-1162.  Full Text
    • Hughes, GC, Barfield, ME, Shah, AA, Williams, JB, Kuchibhatla, M, Hanna, JM, Andersen, ND, and McCann, RL. "Staged total abdominal debranching and thoracic endovascular aortic repair for thoracoabdominal aneurysm." Journal of Vascular Surgery 56, no. 3 (September 2012): 621-629.  Full Text
    • Andersen, ND, Bhattacharya, SD, Williams, JB, Fosbol, EL, Lockhart, EL, Patel, MB, Gaca, JG, Welsby, IJ, and Hughes, GC. "Intraoperative use of low-dose recombinant activated factor VII during thoracic aortic operations." The Annals of thoracic surgery 93, no. 6 (June 2012): 1921-1928.  Full Text
    • Andersen, ND, Williams, JB, Fosbol, EL, Shah, AA, Bhattacharya, SD, Mehta, RH, and Hughes, GC. "Cardiac catheterization within 1 to 3 days of proximal aortic surgery is not associated with increased postoperative acute kidney injury." The Journal of thoracic and cardiovascular surgery 143, no. 6 (June 2012): 1404-1410.  Full Text
    • Williams, JB, Andersen, ND, Bhattacharya, SD, Scheer, E, Piccini, JP, McCann, RL, and Hughes, GC. "Retrograde ascending aortic dissection as an early complication of thoracic endovascular aortic repair." Journal of Vascular Surgery 55, no. 5 (May 2012): 1255-1262.  Full Text
    • Shah, AA, Craig, DM, Sebek, JK, Haynes, C, Stevens, RC, Muehlbauer, MJ, Granger, CB, Hauser, ER, Newby, LK, Newgard, CB, Kraus, WE, Hughes, GC, and Shah, SH. "Metabolic profiles predict adverse events after coronary artery bypass grafting." The Journal of Thoracic and Cardiovascular Surgery 143, no. 4 (April 2012): 873-878.  Full Text
    • Andersen, ND, Williams, JB, Harrison, JK, and Hughes, GC. "Ascending-descending aortic bypass with valve-sparing root replacement for coarctation with aortic root aneurysm." The Journal of Thoracic and Cardiovascular Surgery 143, no. 2 (February 2012): 514-515.  Full Text
    • Hughes, GC. "Endovascular repair will be the best option for thoracoabdominal aortic aneurysm in 2020." Tex Heart Inst J 39, no. 6 (2012): 834-835. (Review)  Link to Item
    • Kiefer, TL, Wang, A, Hughes, GC, and Bashore, TM. "Management of patients with bicuspid aortic valve disease." Curr Treat Options Cardiovasc Med 13, no. 6 (December 2011): 489-505.  Full Text  Link to Item
    • Lima, B, Williams, JB, Bhattacharya, SD, Shah, AA, Andersen, N, Gaca, JG, and Hughes, GC. "Results of proximal arch replacement using deep hypothermia for circulatory arrest: is moderate hypothermia really justifiable?." The American surgeon 77, no. 11 (November 2011): 1438-1444.
    • Andersen, ND, Bhattacharya, SD, Williams, JB, McCann, RL, and Hughes, GC. "Mycotic aneurysm of the thoracoabdominal aorta in a child with end-stage renal disease." Journal of Vascular Surgery 54, no. 4 (October 2011): 1161-1163.  Full Text
    • Mehta, RH, Honeycutt, E, Patel, UD, Lopes, RD, Williams, JB, Shaw, LK, O'Brien, SM, Califf, RM, Hughes, GC, and Sketch, MH. "Relationship of the time interval between cardiac catheterization and elective coronary artery bypass surgery with postprocedural acute kidney injury." Circulation 124, no. 11 Suppl (September 2011): S149-S155.  Full Text
    • Lee, TC, Andersen, ND, Williams, JB, Bhattacharya, SD, McCann, RL, and Hughes, GC. "Results with a selective revascularization strategy for left subclavian artery coverage during thoracic endovascular aortic repair." The Annals of Thoracic Surgery 92, no. 1 (July 2011): 97-102.  Full Text
    • Lima, B, Williams, JB, Bhattacharya, SD, Shah, AA, Andersen, N, Wang, A, Harrison, JK, and Hughes, GC. "Individualized thoracic aortic replacement for the aortopathy of biscuspid aortic valve disease." The Journal of heart valve disease 20, no. 4 (July 2011): 387-395.
    • Swaminathan, M, Nicoara, A, Phillips-Bute, BG, Aeschlimann, N, Milano, CA, Mackensen, GB, Podgoreanu, MV, Velazquez, EJ, Stafford-Smith, M, Mathew, JP, and Cardiothoracic Anesthesia Research Endeavors (CARE) Group, . "Utility of a simple algorithm to grade diastolic dysfunction and predict outcome after coronary artery bypass graft surgery." Ann Thorac Surg 91, no. 6 (June 2011): 1844-1850.  Full Text  Link to Item
    • Shah, AA, Bhattacharya, SD, McCann, RL, and Hughes, GC. "Pan-aortic hybrid treatment of mega-aorta syndrome." J Vasc Surg 53, no. 5 (May 2011): 1398-1401.  Full Text  Link to Item
    • Williams, JB, McCann, RL, and Hughes, GC. "Total aortic replacement in Loeys-Dietz syndrome." Journal of cardiac surgery 26, no. 3 (May 2011): 304-308.  Full Text
    • Williams, JB, Phillips-Bute, B, Bhattacharya, SD, Shah, AA, Andersen, ND, Altintas, B, Lima, B, Smith, PK, Hughes, GC, and Welsby, IJ. "Predictors of massive transfusion with thoracic aortic procedures involving deep hypothermic circulatory arrest." The Journal of thoracic and cardiovascular surgery 141, no. 5 (May 2011): 1283-1288.  Full Text
    • Parsa, CJ, Williams, JB, Bhattacharya, SD, Wolfe, WG, Daneshmand, MA, McCann, RL, and Hughes, GC. "Midterm results with thoracic endovascular aortic repair for chronic type B aortic dissection with associated aneurysm." The Journal of thoracic and cardiovascular surgery 141, no. 2 (February 2011): 322-327.  Full Text
    • Gaca, JG, Sheng, S, Daneshmand, MA, O'Brien, S, Rankin, JS, Brennan, JM, Hughes, GC, Glower, DD, Gammie, JS, and Smith, PK. "Outcomes for endocarditis surgery in North America: a simplified risk scoring system." The Journal of Thoracic and Cardiovascular Surgery 141, no. 1 (January 2011): 98-106.e1-2-null.  Full Text
    • Hughes, GC. "Aggressive aortic replacement for Loeys-Dietz syndrome." Tex Heart Inst J 38, no. 6 (2011): 663-666.  Link to Item
    • Hughes, GC, Lee, SM, Daneshmand, MA, Bhattacharya, SD, Williams, JB, Tucker, SW, and McCann, RL. "Endovascular repair of descending thoracic aneurysms: results with "on-label" application in the post Food and Drug Administration approval era." The Annals of thoracic surgery 90, no. 1 (July 2010): 83-89.  Full Text
    • Hudson, CCC, Welsby, IJ, Phillips-Bute, B, Mathew, JP, Lutz, A, Chad Hughes, G, Stafford-Smith, M, and Cardiothoracic Anesthesiology Research Endeavors (C.A.R.E.) Group, . "Glycosylated hemoglobin levels and outcome in non-diabetic cardiac surgery patients." Can J Anaesth 57, no. 6 (June 2010): 565-572.  Full Text  Link to Item
    • Parsa, CJ, McCann, RL, and Hughes, GC. "Novel approach to the treatment of distal malperfusion secondary to ascending aortic dissection." J Card Surg 25, no. 2 (March 2010): 220-222.  Full Text  Link to Item
    • Williams, ML, Wechsler, SB, and Hughes, GC. "Two-stage total aortic replacement for Loeys-Dietz syndrome." J Card Surg 25, no. 2 (March 2010): 223-224.  Full Text  Link to Item
    • Andersen, ND, Dubose, J, Shah, A, Lee, T, Wechsler, SB, and Hughes, GC. "Thoracic endografting in a patient with hereditary hemorrhagic telangiectasia presenting with a descending thoracic aneurysm." J Vasc Surg 51, no. 2 (February 2010): 468-470.  Full Text  Link to Item
    • Parsa, CJ, Daneshmand, MA, Lima, B, Balsara, K, McCann, RL, and Hughes, GC. "Utility of remote wireless pressure sensing for endovascular leak detection after endovascular thoracic aneurysm repair." Ann Thorac Surg 89, no. 2 (February 2010): 446-452.  Full Text  Link to Item
    • Parsa, CJ, Schroder, JN, Daneshmand, MA, McCann, RL, and Hughes, GC. "Midterm results for endovascular repair of complicated acute and chronic type B aortic dissection." Ann Thorac Surg 89, no. 1 (January 2010): 97-102.  Full Text  Link to Item
    • Williams, ML, Sheng, S, Gammie, JS, Rankin, JS, Smith, PK, and Hughes, GC. "Aortic dissection as a complication of cardiac surgery: Report from the society of thoracic surgeons database." Annals of Thoracic Surgery 90, no. 6 (2010): 1812-1816.  Full Text
    • Hughes, GC, Daneshmand, MA, Balsara, KR, Achneck, HA, Sileshi, B, Lee, SM, and McCann, RL. ""Hybrid" repair of aneurysms of the transverse aortic arch: midterm results." Ann Thorac Surg 88, no. 6 (December 2009): 1882-1887.  Full Text  Link to Item
    • Rajagopal, K, Rogers, JG, Lodge, AJ, Gaca, JG, McCann, RL, Milano, CA, and Hughes, GC. "Two-stage total cardioaortic replacement for end-stage heart and aortic disease in Marfan syndrome: case report and review of the literature." J Heart Lung Transplant 28, no. 9 (September 2009): 958-963. (Review)  Full Text  Link to Item
    • Atkins, BZ, Wooten, MK, Kistler, J, Hurley, K, Hughes, GC, and Wolfe, WG. "Does negative pressure wound therapy have a role in preventing poststernotomy wound complications?." Surgical Innovation 16, no. 2 (June 2009): 140-146.  Full Text
    • Parsa, CJ, Milano, CA, Proia, AD, Mackensen, GB, and Hughes, GC. "A previously unreported complication of apicoaortic conduit for severe aortic stenosis." Ann Thorac Surg 87, no. 3 (March 2009): 927-928.  Full Text  Link to Item
    • Hughes, GC, and McCann, RL. "Hybrid thoracoabdominal aortic aneurysm repair: concomitant visceral revascularization and endovascular aneurysm exclusion." Semin Thorac Cardiovasc Surg 21, no. 4 (2009): 355-362. (Review)  Full Text  Link to Item
    • Parsa, CJ, and Hughes, GC. "Surgical options to contend with thoracic aortic pathology." Semin Roentgenol 44, no. 1 (January 2009): 29-51. (Review)  Full Text  Link to Item
    • Swaminathan, M, Stuart, M, Hughes, GC, Jaggers, J, Hill, SE, Milano, CA, Bennett-Guerrero, E, and Stafford-Smith, M. "Institutional response to FDA warning on aprotinin and impact on outcomes." Hsr Proceedings in Intensive Care & Cardiovascular Anesthesia 1, no. 1 (January 2009): 30-36.
    • Hughes, GC, Sulzer, CF, McCann, RL, and Swaminathan, M. "Endovascular approaches to complex thoracic aortic disease." Semin Cardiothorac Vasc Anesth 12, no. 4 (December 2008): 298-319. (Review)  Full Text  Link to Item
    • Hughes, GC, Daneshmand, MA, Swaminathan, M, Nienaber, JJ, Bush, EL, Husain, AH, Wolfe, WG, and McCann, RL. ""Real world" thoracic endografting: results with the Gore TAG device 2 years after U.S. FDA approval." The Annals of thoracic surgery 86, no. 5 (November 2008): 1530-1537.  Full Text
    • Mullenix, PS, Parsa, CJ, Mackensen, GB, Jollis, JG, Harrison, JK, and Hughes, GC. "Pannus-related prosthetic valve dysfunction and life-threatening aortic regurgitation." J Heart Valve Dis 17, no. 6 (November 2008): 666-669.  Link to Item
    • Hughes, GC, Nienaber, JJ, Bush, EL, Daneshmand, MA, and McCann, RL. "Use of custom Dacron branch grafts for "hybrid" aortic debranching during endovascular repair of thoracic and thoracoabdominal aortic aneurysms." The Journal of thoracic and cardiovascular surgery 136, no. 1 (July 2008): 21-28.e6.  Full Text
    • Husain, AM, Swaminathan, M, McCann, RL, and Hughes, GC. "Neurophysiologic intraoperative monitoring during endovascular stent graft repair of the descending thoracic aorta." J Clin Neurophysiol 24, no. 4 (August 2007): 328-335.  Full Text  Link to Item
    • Rajagopal, K, Lima, B, Harrison, JK, Swaminathan, M, McCann, RL, and Hughes, GC. "Endovascular thoracic aortic aneurysm repair with concomitant myocardial and carotid revascularization." Ann Thorac Surg 84, no. 1 (July 2007): e1-e3.  Full Text  Link to Item
    • Swaminathan, M, Mackensen, GB, Podgoreanu, MV, McCann, RL, Mathew, JP, and Hughes, GC. "Spontaneous echocardiographic contrast indicating successful endoleak management." Anesth Analg 104, no. 5 (May 2007): 1037-1039.  Full Text  Link to Item
    • Hughes, GC, Swaminathan, M, and Wolfe, WG. "Reimplantation technique (David operation) for multiple sinus of valsalva aneurysms." Ann Thorac Surg 82, no. 2 (August 2006): e14-e16.  Full Text  Link to Item
    • Lima, B, Hughes, GC, Lemaire, A, Jaggers, J, Glower, DD, and Wolfe, WG. "Short-term and intermediate-term outcomes of aortic root replacement with St. Jude mechanical conduits and aortic allografts." Ann Thorac Surg 82, no. 2 (August 2006): 579-585.  Full Text  Link to Item
    • Hughes, GC, and Annex, BH. "Angiogenic therapy for coronary artery and peripheral arterial disease." Expert Rev Cardiovasc Ther 3, no. 3 (May 2005): 521-535. (Review)  Full Text  Link to Item
    • Hughes, GC, Biswas, SS, Yin, B, Coleman, RE, DeGrado, TR, Landolfo, CK, Lowe, JE, Annex, BH, and Landolfo, KP. "Therapeutic angiogenesis in chronically ischemic porcine myocardium: comparative effects of bFGF and VEGF." Ann Thorac Surg 77, no. 3 (March 2004): 812-818.  Full Text  Link to Item
    • Biswas, SS, Hughes, GC, Scarborough, JE, Domkowski, PW, Diodato, L, Smith, ML, Landolfo, C, Lowe, JE, Annex, BH, and Landolfo, KP. "Intramyocardial and intracoronary basic fibroblast growth factor in porcine hibernating myocardium: a comparative study." J Thorac Cardiovasc Surg 127, no. 1 (January 2004): 34-43.  Full Text  Link to Item
    • Hughes, GC, Baklanov, DV, Biswas, SS, Pippen, AM, DeGrado, TR, Coleman, RE, Landolfo, CK, Lowe, JE, Annex, BH, and Landolfo, KP. "Regional cardiac sympathetic innervation early and late after transmyocardial laser revascularization." J Card Surg 19, no. 1 (January 2004): 21-27.  Link to Item
    • Hughes, GC, Post, MJ, Simons, M, and Annex, BH. "Translational physiology: porcine models of human coronary artery disease: implications for preclinical trials of therapeutic angiogenesis." Journal of Applied Physiology (Bethesda, Md. : 1985) 94, no. 5 (May 2003): 1689-1701. (Review)  Full Text
    • Hughes, GC, Biswas, SS, Yin, B, Baklanov, DV, Annex, BH, Coleman, RE, DeGrado, TR, Landolfo, CK, Landolfo, KP, and Lowe, JE. "A comparison of mechanical and laser transmyocardial revascularization for induction of angiogenesis and arteriogenesis in chronically ischemic myocardium." J Am Coll Cardiol 39, no. 7 (April 3, 2002): 1220-1228.  Link to Item
    • Biswas, S, Clements, F, Diodato, L, Hughes, GC, and Landolfo, K. "Changes in systolic and diastolic function during multivessel off-pump coronary bypass grafting." Eur J Cardiothorac Surg 20, no. 5 (November 2001): 913-917.  Link to Item
    • Hughes, GC, Landolfo, CK, Yin, B, DeGrado, TR, Coleman, RE, Landolfo, KP, and Lowe, JE. "Is chronically dysfunctional yet viable myocardium distal to a severe coronary stenosis hypoperfused?." Ann Thorac Surg 72, no. 1 (July 2001): 163-168.  Link to Item
    • Domkowski, PW, Hughes, GC, Scarborough, JE, Diodato, LH, Smith, ML, Landolfo, KP, and Lowe, JE. "Lasers in cardiothoracic surgery." Optics and Photonics News 12, no. 7 (2001): 36-41.
    • Hughes, GC, Kypson, AP, Annex, BH, Yin, B, St Louis, JD, Biswas, SS, Coleman, RE, DeGrado, TR, Donovan, CL, Landolfo, KP, and Lowe, JE. "Induction of angiogenesis after TMR: a comparison of holmium: YAG, CO2, and excimer lasers." The Annals of Thoracic Surgery 70, no. 2 (August 2000): 504-509.  Full Text
    • St Louis, JD, Hughes, GC, Kypson, AP, DeGrado, TR, Donovan, CL, Coleman, RE, Yin, B, Steenbergen, C, Landolfo, KP, and Lowe, JE. "An experimental model of chronic myocardial hibernation." Ann Thorac Surg 69, no. 5 (May 2000): 1351-1357.  Link to Item
    • Hughes, GC, Shah, AS, Yin, B, Shu, M, Donovan, CL, Glower, DD, Lowe, JE, and Landolfo, KP. "Early postoperative changes in regional systolic and diastolic left ventricular function after transmyocardial laser revascularization: a comparison of holmium:YAG and CO2 lasers." J Am Coll Cardiol 35, no. 4 (March 15, 2000): 1022-1030.  Link to Item
    • Landolfo, CK, Landolfo, KP, Hughes, GC, Coleman, ER, Coleman, RB, and Lowe, JE. "Intermediate-term clinical outcome following transmyocardial laser revascularization in patients with refractory angina pectoris." Circulation 100, no. 19 Suppl (November 9, 1999): II128-II133.  Link to Item
    • Hughes, GC, Annex, BH, Yin, B, Pippen, AM, Lin, P, Kypson, AP, Peters, KG, Lowe, JE, and Landolfo, KP. "Transmyocardial laser revascularization limits in vivo adenoviral-mediated gene transfer in porcine myocardium." Cardiovasc Res 44, no. 1 (October 1999): 81-90.  Link to Item
    • Hughes, GC, Abdel-aleem, S, Biswas, SS, Landolfo, KP, and Lowe, JE. "Transmyocardial laser revascularization: experimental and clinical results." Can J Cardiol 15, no. 7 (July 1999): 797-806. (Review)  Link to Item
    • Abdel-Aleem, S, St Louis, JD, Hughes, GC, and Lowe, JE. "Metabolic changes in the normal and hypoxic neonatal myocardium." Ann N Y Acad Sci 874 (June 30, 1999): 254-261. (Review)  Link to Item
    • Hughes, GC, Kypson, AP, St Louis, JD, Annex, BH, Coleman, RE, DeGrado, TR, Donovan, CL, Lowe, JE, and Landolfo, KP. "Improved perfusion and contractile reserve after transmyocardial laser revascularization in a model of hibernating myocardium." Ann Thorac Surg 67, no. 6 (June 1999): 1714-1720.  Link to Item
    • Hughes, GC, Landolfo, KP, Lowe, JE, Coleman, RB, and Donovan, CL. "Diagnosis, incidence, and clinical significance of early postoperative ischemia after transmyocardial laser revascularization." Am Heart J 137, no. 6 (June 1999): 1163-1168.  Link to Item
    • Hughes, GC, Ketchersid, TL, Lenzen, JM, and Lowe, JE. "Thoracic complications of peritoneal dialysis." Ann Thorac Surg 67, no. 5 (May 1999): 1518-1522.  Link to Item
    • Hughes, GC, Landolfo, KP, Lowe, JE, Coleman, RB, and Donovan, CL. "Perioperative morbidity and mortality after transmyocardial laser revascularization: incidence and risk factors for adverse events." J Am Coll Cardiol 33, no. 4 (March 15, 1999): 1021-1026.  Link to Item
    • Hughes, GC, Smith, TP, Eachempati, SR, Vaslef, SN, and Reed, RL. "The use of a temporary vena caval interruption device in high-risk trauma patients unable to receive standard venous thromboembolism prophylaxis." J Trauma 46, no. 2 (February 1999): 246-249.  Link to Item
    • Abdel-aleem, S, El-Guindy, N, Sallam, TI, Hughes, GC, and Lowe, JE. "Stimulation of long-chain fatty acid uptake by dipyridamole in isolated myocytes." J Cardiovasc Pharmacol 33, no. 1 (January 1999): 43-48.  Link to Item
    • Lowe, JE, Hughes, GC, and Biswas, SS. "Non-blood-contacting biventricular support: Direct mechanical ventricular actuation." Operative Techniques in Thoracic and Cardiovascular Surgery 4, no. 4 (1999): 345-351.  Full Text
    • Hughes, GC, Lowe, JE, Kypson, AP, St Louis, JD, Pippen, AM, Peters, KG, Coleman, RE, DeGrado, TR, Donovan, CL, Annex, BH, and Landolfo, KP. "Neovascularization after transmyocardial laser revascularization in a model of chronic ischemia." Ann Thorac Surg 66, no. 6 (December 1998): 2029-2036.  Link to Item
    • Hughes, GC, Donovan, CL, Lowe, JE, and Landolfo, KP. "Combined TMR and mitral valve replacement via left thoracotomy." Ann Thorac Surg 65, no. 4 (April 1998): 1141-1143.  Link to Item
    • Hasselman, CT, Best, TM, Hughes, C, Martinez, S, and Garrett, WE. "An explanation for various rectus femoris strain injuries using previously undescribed muscle architecture." The American Journal of Sports Medicine 23, no. 4 (July 1995): 493-499.  Full Text
    • Hughes, C, Hasselman, CT, Best, TM, Martinez, S, and Garrett, WE. "Incomplete, intrasubstance strain injuries of the rectus femoris muscle." The American Journal of Sports Medicine 23, no. 4 (July 1995): 500-506.  Full Text
    • Chad Hughes, G, Andersen, ND, and McCann, RL. "Endovascular Repair of Chronic Type B Aortic Dissection With Aneurysmal Degeneration (Accepted)." Operative Techniques in Thoracic and Cardiovascular Surgery 18, no. 2: 101-116.  Full Text

  • Other Articles

    • Hughes, GC. "Invited Commentary." The Annals of thoracic surgery 101, no. 3 (March 2016): 973-.  Full Text
    • Hughes, GC, and Mathew, JP. "Invited Commentary." The Annals of thoracic surgery 101, no. 1 (January 2016): 152-153.  Full Text
    • Englum, BR, Ganapathi, AM, and Hughes, GC. "Reply: To PMID 25301369." The Annals of thoracic surgery 100, no. 4 (October 2015): 1508-. (Letter)  Full Text
    • Kiefer, TL, Halim, S, Wang, A, Kevin Harrison, J, Gaca, J, and Hughes, GC. "Fluoroscopic characterization of surgical bioprosthetic heart valves." Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 85, no. 7 (June 2015): 1274-1276. (Letter)  Full Text
    • Chen, EP, Garcia, , Preventza, , Hughes, GC, and Patel, H. "Discussion." Annals of Thoracic Surgery 100, no. 2 (January 1, 2015): 514-515.  Full Text
    • Andersen, ND, and Hughes, GC. "Reply to the Editor." Journal of Thoracic and Cardiovascular Surgery 145, no. 1 (2013): 313-314.  Full Text
    • Andersen, ND, and Hughes, GC. "Reply to the editor." Journal of Thoracic and Cardiovascular Surgery 144, no. 1 (2012): 280-281.  Full Text
    • Parsa, CJ, and Hughes, GC. "Rarity of Aortic Thrombus After Aortic Valve Bypass (Apicoaortic Conduit) Surgery Reply." ANNALS OF THORACIC SURGERY 89, no. 1 (January 2010): 342-342.  Full Text  Link to Item
    • Hughes, GC. "Cellular models of hibernating myocardium: Implications for future research." Cardiovascular Research 51, no. 2 (2001): 191-193.  Full Text
    • Domkowski, PW, Hughes, GC, and Lowe, JE. "Ameroid constrictor versus hydraulic occluder: creation of hibernating myocardium." Ann Thorac Surg 69, no. 6 (June 2000): 1984-. (Letter)  Link to Item
    • Beranek, JT, Hughes, GC, Annex, BH, Peters, KG, Paavonen, KJA, Lowe, JE, and Landolfo, KP. "Lymphatic angiogenesis induced by transmyocardial laser revascularization (multiple letters) [5]." Annals of Thoracic Surgery 68, no. 1 (1999): 295--.

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