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George Charles Hughes IV

Professor of Surgery
Surgery, Cardiovascular and Thoracic Surgery
Box 3051 Med Ctr, Durham, NC 27710
3580 White Zone, Duke South, Durham, NC 27710

Current Appointments & Affiliations


Professor of Surgery · 2020 - Present Surgery, Cardiovascular and Thoracic Surgery, Surgery

Recent Publications


Outcomes of Transcatheter Aortic Valve Replacement in Low-Risk Patients in the United States: A Report From the STS/ACC TVT Registry.

Journal Article Circulation · April 22, 2025 BACKGROUND: Real-world low-risk transcatheter aortic valve replacement (TAVR) outcomes in the United States have not been assessed comprehensively versus pivotal trials, which is a key component of measuring the quality of clinical technology adoption. MET ... Full text Link to item Cite

Influence of Failure to Rescue on Mortality After Transcatheter Aortic Valve Replacement

Journal Article Annals of Thoracic Surgery Short Reports · April 2025 Full text Cite
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Recent Grants


GORE® EXCLUDER® Thoracoabdominal Branch Endoprosthesis Post-Approval Study

Clinical TrialPrincipal Investigator · Awarded by W. L. Gore & Associates, Inc. · 2024 - 2040

Long-term Characterization of GORE® TAG® Conformable Thoracic Stent Graft with ACTIVE CONTROL System Performance

Clinical TrialPrincipal Investigator · Awarded by W. L. Gore & Associates, Inc. · 2025 - 2038

EXTEND Thoraflex Hybrid Study

Clinical TrialPrincipal Investigator · Awarded by Vascutek Limited · 2023 - 2038

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Education, Training & Certifications


Duke University · 1995 M.D.