Metabolomics, pathway regulation, and pathway discovery.

Journal Article (Journal Article;Review)

Metabolomics is a data-based research strategy, the aims of which are to identify biomarker pictures of metabolic systems and metabolic perturbations and to formulate hypotheses to be tested. It involves the assay by mass spectrometry or NMR of many metabolites present in the biological system investigated. In this minireview, we outline studies in which metabolomics led to useful biomarkers of metabolic processes. We also illustrate how the discovery potential of metabolomics is enhanced by associating it with stable isotopic techniques.

Full Text

Duke Authors

Cited Authors

  • Zhang, G-F; Sadhukhan, S; Tochtrop, GP; Brunengraber, H

Published Date

  • July 8, 2011

Published In

Volume / Issue

  • 286 / 27

Start / End Page

  • 23631 - 23635

PubMed ID

  • 21566142

Pubmed Central ID

  • PMC3129142

Electronic International Standard Serial Number (EISSN)

  • 1083-351X

Digital Object Identifier (DOI)

  • 10.1074/jbc.R110.171405

Language

  • eng

Conference Location

  • United States