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Metabolomics, pathway regulation, and pathway discovery.

Publication ,  Journal Article
Zhang, G-F; Sadhukhan, S; Tochtrop, GP; Brunengraber, H
Published in: J Biol Chem
July 8, 2011

Metabolomics is a data-based research strategy, the aims of which are to identify biomarker pictures of metabolic systems and metabolic perturbations and to formulate hypotheses to be tested. It involves the assay by mass spectrometry or NMR of many metabolites present in the biological system investigated. In this minireview, we outline studies in which metabolomics led to useful biomarkers of metabolic processes. We also illustrate how the discovery potential of metabolomics is enhanced by associating it with stable isotopic techniques.

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Published In

J Biol Chem

DOI

EISSN

1083-351X

Publication Date

July 8, 2011

Volume

286

Issue

27

Start / End Page

23631 / 23635

Location

United States

Related Subject Headings

  • Metabolomics
  • Metabolome
  • Mass Spectrometry
  • Magnetic Resonance Spectroscopy
  • Biomarkers
  • Biochemistry & Molecular Biology
  • Animals
  • 34 Chemical sciences
  • 32 Biomedical and clinical sciences
  • 31 Biological sciences
 

Citation

APA
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ICMJE
MLA
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Zhang, G.-F., Sadhukhan, S., Tochtrop, G. P., & Brunengraber, H. (2011). Metabolomics, pathway regulation, and pathway discovery. J Biol Chem, 286(27), 23631–23635. https://doi.org/10.1074/jbc.R110.171405
Zhang, Guo-Fang, Sushabhan Sadhukhan, Gregory P. Tochtrop, and Henri Brunengraber. “Metabolomics, pathway regulation, and pathway discovery.J Biol Chem 286, no. 27 (July 8, 2011): 23631–35. https://doi.org/10.1074/jbc.R110.171405.
Zhang G-F, Sadhukhan S, Tochtrop GP, Brunengraber H. Metabolomics, pathway regulation, and pathway discovery. J Biol Chem. 2011 Jul 8;286(27):23631–5.
Zhang, Guo-Fang, et al. “Metabolomics, pathway regulation, and pathway discovery.J Biol Chem, vol. 286, no. 27, July 2011, pp. 23631–35. Pubmed, doi:10.1074/jbc.R110.171405.
Zhang G-F, Sadhukhan S, Tochtrop GP, Brunengraber H. Metabolomics, pathway regulation, and pathway discovery. J Biol Chem. 2011 Jul 8;286(27):23631–23635.

Published In

J Biol Chem

DOI

EISSN

1083-351X

Publication Date

July 8, 2011

Volume

286

Issue

27

Start / End Page

23631 / 23635

Location

United States

Related Subject Headings

  • Metabolomics
  • Metabolome
  • Mass Spectrometry
  • Magnetic Resonance Spectroscopy
  • Biomarkers
  • Biochemistry & Molecular Biology
  • Animals
  • 34 Chemical sciences
  • 32 Biomedical and clinical sciences
  • 31 Biological sciences