Metabolomics, pathway regulation, and pathway discovery.
Publication
, Journal Article
Zhang, G-F; Sadhukhan, S; Tochtrop, GP; Brunengraber, H
Published in: J Biol Chem
July 8, 2011
Metabolomics is a data-based research strategy, the aims of which are to identify biomarker pictures of metabolic systems and metabolic perturbations and to formulate hypotheses to be tested. It involves the assay by mass spectrometry or NMR of many metabolites present in the biological system investigated. In this minireview, we outline studies in which metabolomics led to useful biomarkers of metabolic processes. We also illustrate how the discovery potential of metabolomics is enhanced by associating it with stable isotopic techniques.
Duke Scholars
Published In
J Biol Chem
DOI
EISSN
1083-351X
Publication Date
July 8, 2011
Volume
286
Issue
27
Start / End Page
23631 / 23635
Location
United States
Related Subject Headings
- Metabolomics
- Metabolome
- Mass Spectrometry
- Magnetic Resonance Spectroscopy
- Biomarkers
- Biochemistry & Molecular Biology
- Animals
- 34 Chemical sciences
- 32 Biomedical and clinical sciences
- 31 Biological sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Zhang, G.-F., Sadhukhan, S., Tochtrop, G. P., & Brunengraber, H. (2011). Metabolomics, pathway regulation, and pathway discovery. J Biol Chem, 286(27), 23631–23635. https://doi.org/10.1074/jbc.R110.171405
Zhang, Guo-Fang, Sushabhan Sadhukhan, Gregory P. Tochtrop, and Henri Brunengraber. “Metabolomics, pathway regulation, and pathway discovery.” J Biol Chem 286, no. 27 (July 8, 2011): 23631–35. https://doi.org/10.1074/jbc.R110.171405.
Zhang G-F, Sadhukhan S, Tochtrop GP, Brunengraber H. Metabolomics, pathway regulation, and pathway discovery. J Biol Chem. 2011 Jul 8;286(27):23631–5.
Zhang, Guo-Fang, et al. “Metabolomics, pathway regulation, and pathway discovery.” J Biol Chem, vol. 286, no. 27, July 2011, pp. 23631–35. Pubmed, doi:10.1074/jbc.R110.171405.
Zhang G-F, Sadhukhan S, Tochtrop GP, Brunengraber H. Metabolomics, pathway regulation, and pathway discovery. J Biol Chem. 2011 Jul 8;286(27):23631–23635.
Published In
J Biol Chem
DOI
EISSN
1083-351X
Publication Date
July 8, 2011
Volume
286
Issue
27
Start / End Page
23631 / 23635
Location
United States
Related Subject Headings
- Metabolomics
- Metabolome
- Mass Spectrometry
- Magnetic Resonance Spectroscopy
- Biomarkers
- Biochemistry & Molecular Biology
- Animals
- 34 Chemical sciences
- 32 Biomedical and clinical sciences
- 31 Biological sciences