Randomized trial of an uncertainty self-management telephone intervention for patients awaiting liver transplant.

Journal Article (Journal Article)

OBJECTIVE: We tested an uncertainty self-management telephone intervention (SMI) with patients awaiting liver transplant and their caregivers. METHODS: Participants were recruited from four transplant centers and completed questionnaires at baseline, 10, and 12 weeks from baseline (generally two and four weeks after intervention delivery, respectively). Dyads were randomized to either SMI (n=56) or liver disease education (LDE; n=59), both of which involved six weekly telephone sessions. SMI participants were taught coping skills and uncertainty management strategies while LDE participants learned about liver function and how to stay healthy. Outcomes included illness uncertainty, uncertainty management, depression, anxiety, self-efficacy, and quality of life. General linear models were used to test for group differences. RESULTS: No differences were found between the SMI and LDE groups for study outcomes. CONCLUSION: This trial offers insight regarding design for future interventions that may allow greater flexibility in length of delivery beyond our study's 12-week timeframe. PRACTICE IMPLICATIONS: Our study was designed for the time constraints of today's clinical practice setting. This trial is a beginning point to address the unmet needs of these patients and their caregivers as they wait for transplants that could save their lives.

Full Text

Duke Authors

Cited Authors

  • Bailey, DE; Hendrix, CC; Steinhauser, KE; Stechuchak, KM; Porter, LS; Hudson, J; Olsen, MK; Muir, A; Lowman, S; DiMartini, A; Salonen, LW; Tulsky, JA

Published Date

  • March 2017

Published In

Volume / Issue

  • 100 / 3

Start / End Page

  • 509 - 517

PubMed ID

  • 28277289

Pubmed Central ID

  • PMC5350046

Electronic International Standard Serial Number (EISSN)

  • 1873-5134

Digital Object Identifier (DOI)

  • 10.1016/j.pec.2016.10.017


  • eng

Conference Location

  • Ireland