Update on the Diagnosis and Treatment of Spontaneous Intracranial Hypotension.

Journal Article (Review;Journal Article)

Purpose of review

The purpose of this study is to provide an update on recent developments in the understanding, diagnosis, and treatment of spontaneous intracranial hypotension (SIH).

Recent findings

SIH is an important cause of headaches caused by spinal cerebrospinal fluid (CSF) leaks, with an increasingly broad spectrum of clinical presentations and diagnostic findings. A simple conception of the condition as being defined by the presence of low CSF pressure is no longer sufficient or accurate. A number of etiologies for spinal CSF leaks have been identified, including the recent discovery of CSF-venous fistulas, and these various etiologies may require different diagnostic and therapeutic pathways in order to affect a cure. Familiarity with the spectrum of presentations and causes of SIH is critical to accurate and timely diagnosis and management. Challenges exist in both diagnosis and treatment, and require understanding of the underlying pathogenesis of the condition in order to appropriately select testing and treatment. Prospective studies are needed going forward in order to inform workup and guide treatment decisions.

Full Text

Duke Authors

Cited Authors

  • Kranz, PG; Malinzak, MD; Amrhein, TJ; Gray, L

Published Date

  • August 2017

Published In

Volume / Issue

  • 21 / 8

Start / End Page

  • 37 -

PubMed ID

  • 28755201

Electronic International Standard Serial Number (EISSN)

  • 1534-3081

International Standard Serial Number (ISSN)

  • 1531-3433

Digital Object Identifier (DOI)

  • 10.1007/s11916-017-0639-3


  • eng