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Safety and side-effect profile of intrathecal morphine in a diverse patient population undergoing total knee and hip arthroplasty.

Publication ,  Journal Article
Hess, SR; Lahaye, LA; Waligora, AC; Sima, AP; Jiranek, WA; Golladay, GJ
Published in: Eur J Orthop Surg Traumatol
January 2019

Intrathecal morphine (ITM) can be useful for postoperative analgesia following lower extremity joint arthroplasty, but concerns exist regarding potential dose-related side effects. In this study, we examined the safety and efficacy of ITM in patients undergoing lower extremity joint arthroplasty. We hypothesized that there would be (1) direct relationship between dosing and side effects, and (2) an inverse relationship between ITM dosing and 24-hour postoperative opioid requirement.

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Published In

Eur J Orthop Surg Traumatol

DOI

EISSN

1432-1068

Publication Date

January 2019

Volume

29

Issue

1

Start / End Page

125 / 129

Location

France

Related Subject Headings

  • Time Factors
  • Sex Factors
  • Retrospective Studies
  • Respiratory Insufficiency
  • Pruritus
  • Postoperative Nausea and Vomiting
  • Pain, Postoperative
  • Orthopedics
  • Morphine
  • Middle Aged
 

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Hess, S. R., Lahaye, L. A., Waligora, A. C., Sima, A. P., Jiranek, W. A., & Golladay, G. J. (2019). Safety and side-effect profile of intrathecal morphine in a diverse patient population undergoing total knee and hip arthroplasty. Eur J Orthop Surg Traumatol, 29(1), 125–129. https://doi.org/10.1007/s00590-018-2293-9
Hess, Shane R., Laura A. Lahaye, Andrew C. Waligora, Adam P. Sima, William A. Jiranek, and Gregory J. Golladay. “Safety and side-effect profile of intrathecal morphine in a diverse patient population undergoing total knee and hip arthroplasty.Eur J Orthop Surg Traumatol 29, no. 1 (January 2019): 125–29. https://doi.org/10.1007/s00590-018-2293-9.
Hess SR, Lahaye LA, Waligora AC, Sima AP, Jiranek WA, Golladay GJ. Safety and side-effect profile of intrathecal morphine in a diverse patient population undergoing total knee and hip arthroplasty. Eur J Orthop Surg Traumatol. 2019 Jan;29(1):125–9.
Hess, Shane R., et al. “Safety and side-effect profile of intrathecal morphine in a diverse patient population undergoing total knee and hip arthroplasty.Eur J Orthop Surg Traumatol, vol. 29, no. 1, Jan. 2019, pp. 125–29. Pubmed, doi:10.1007/s00590-018-2293-9.
Hess SR, Lahaye LA, Waligora AC, Sima AP, Jiranek WA, Golladay GJ. Safety and side-effect profile of intrathecal morphine in a diverse patient population undergoing total knee and hip arthroplasty. Eur J Orthop Surg Traumatol. 2019 Jan;29(1):125–129.
Journal cover image

Published In

Eur J Orthop Surg Traumatol

DOI

EISSN

1432-1068

Publication Date

January 2019

Volume

29

Issue

1

Start / End Page

125 / 129

Location

France

Related Subject Headings

  • Time Factors
  • Sex Factors
  • Retrospective Studies
  • Respiratory Insufficiency
  • Pruritus
  • Postoperative Nausea and Vomiting
  • Pain, Postoperative
  • Orthopedics
  • Morphine
  • Middle Aged