Safety and side-effect profile of intrathecal morphine in a diverse patient population undergoing total knee and hip arthroplasty.
Publication
, Journal Article
Hess, SR; Lahaye, LA; Waligora, AC; Sima, AP; Jiranek, WA; Golladay, GJ
Published in: Eur J Orthop Surg Traumatol
January 2019
Intrathecal morphine (ITM) can be useful for postoperative analgesia following lower extremity joint arthroplasty, but concerns exist regarding potential dose-related side effects. In this study, we examined the safety and efficacy of ITM in patients undergoing lower extremity joint arthroplasty. We hypothesized that there would be (1) direct relationship between dosing and side effects, and (2) an inverse relationship between ITM dosing and 24-hour postoperative opioid requirement.
Duke Scholars
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Published In
Eur J Orthop Surg Traumatol
DOI
EISSN
1432-1068
Publication Date
January 2019
Volume
29
Issue
1
Start / End Page
125 / 129
Location
France
Related Subject Headings
- Time Factors
- Sex Factors
- Retrospective Studies
- Respiratory Insufficiency
- Pruritus
- Postoperative Nausea and Vomiting
- Pain, Postoperative
- Orthopedics
- Morphine
- Middle Aged
Citation
APA
Chicago
ICMJE
MLA
NLM
Hess, S. R., Lahaye, L. A., Waligora, A. C., Sima, A. P., Jiranek, W. A., & Golladay, G. J. (2019). Safety and side-effect profile of intrathecal morphine in a diverse patient population undergoing total knee and hip arthroplasty. Eur J Orthop Surg Traumatol, 29(1), 125–129. https://doi.org/10.1007/s00590-018-2293-9
Published In
Eur J Orthop Surg Traumatol
DOI
EISSN
1432-1068
Publication Date
January 2019
Volume
29
Issue
1
Start / End Page
125 / 129
Location
France
Related Subject Headings
- Time Factors
- Sex Factors
- Retrospective Studies
- Respiratory Insufficiency
- Pruritus
- Postoperative Nausea and Vomiting
- Pain, Postoperative
- Orthopedics
- Morphine
- Middle Aged