Adverse hypersensitivity reactions to mesna as adjunctive therapy for cyclophosphamide.
Journal Article (Journal Article;Review)
Mesna is widely used for the prevention of cyclophosphamide-related hemorrhagic cystitis. It has been associated with hypersensitivity-like cutaneous and systemic reactions in adult patients. We report a series of children with malignant disease, who developed such reactions following mesna administration and discuss possible mechanisms and management issues.
Full Text
Duke Authors
Cited Authors
- Khaw, SL; Downie, PA; Waters, KD; Ashley, DM; Heath, JA
Published Date
- September 2007
Published In
Volume / Issue
- 49 / 3
Start / End Page
- 341 - 343
PubMed ID
- 16333822
Pubmed Central ID
- 16333822
International Standard Serial Number (ISSN)
- 1545-5009
Digital Object Identifier (DOI)
- 10.1002/pbc.20617
Language
- eng
Conference Location
- United States