
Adverse hypersensitivity reactions to mesna as adjunctive therapy for cyclophosphamide.
Publication
, Journal Article
Khaw, SL; Downie, PA; Waters, KD; Ashley, DM; Heath, JA
Published in: Pediatr Blood Cancer
September 2007
Mesna is widely used for the prevention of cyclophosphamide-related hemorrhagic cystitis. It has been associated with hypersensitivity-like cutaneous and systemic reactions in adult patients. We report a series of children with malignant disease, who developed such reactions following mesna administration and discuss possible mechanisms and management issues.
Duke Scholars
Published In
Pediatr Blood Cancer
DOI
ISSN
1545-5009
Publication Date
September 2007
Volume
49
Issue
3
Start / End Page
341 / 343
Location
United States
Related Subject Headings
- Spinal Neoplasms
- Protective Agents
- Osteosarcoma
- Oncology & Carcinogenesis
- Mesna
- Medulloblastoma
- Humans
- Female
- Drug Hypersensitivity
- Cyclophosphamide
Citation
APA
Chicago
ICMJE
MLA
NLM
Khaw, S. L., Downie, P. A., Waters, K. D., Ashley, D. M., & Heath, J. A. (2007). Adverse hypersensitivity reactions to mesna as adjunctive therapy for cyclophosphamide. Pediatr Blood Cancer, 49(3), 341–343. https://doi.org/10.1002/pbc.20617
Khaw, Seong L., Peter A. Downie, Keith D. Waters, David M. Ashley, and John A. Heath. “Adverse hypersensitivity reactions to mesna as adjunctive therapy for cyclophosphamide.” Pediatr Blood Cancer 49, no. 3 (September 2007): 341–43. https://doi.org/10.1002/pbc.20617.
Khaw SL, Downie PA, Waters KD, Ashley DM, Heath JA. Adverse hypersensitivity reactions to mesna as adjunctive therapy for cyclophosphamide. Pediatr Blood Cancer. 2007 Sep;49(3):341–3.
Khaw, Seong L., et al. “Adverse hypersensitivity reactions to mesna as adjunctive therapy for cyclophosphamide.” Pediatr Blood Cancer, vol. 49, no. 3, Sept. 2007, pp. 341–43. Pubmed, doi:10.1002/pbc.20617.
Khaw SL, Downie PA, Waters KD, Ashley DM, Heath JA. Adverse hypersensitivity reactions to mesna as adjunctive therapy for cyclophosphamide. Pediatr Blood Cancer. 2007 Sep;49(3):341–343.

Published In
Pediatr Blood Cancer
DOI
ISSN
1545-5009
Publication Date
September 2007
Volume
49
Issue
3
Start / End Page
341 / 343
Location
United States
Related Subject Headings
- Spinal Neoplasms
- Protective Agents
- Osteosarcoma
- Oncology & Carcinogenesis
- Mesna
- Medulloblastoma
- Humans
- Female
- Drug Hypersensitivity
- Cyclophosphamide