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Adverse hypersensitivity reactions to mesna as adjunctive therapy for cyclophosphamide.

Publication ,  Journal Article
Khaw, SL; Downie, PA; Waters, KD; Ashley, DM; Heath, JA
Published in: Pediatr Blood Cancer
September 2007

Mesna is widely used for the prevention of cyclophosphamide-related hemorrhagic cystitis. It has been associated with hypersensitivity-like cutaneous and systemic reactions in adult patients. We report a series of children with malignant disease, who developed such reactions following mesna administration and discuss possible mechanisms and management issues.

Duke Scholars

Published In

Pediatr Blood Cancer

DOI

ISSN

1545-5009

Publication Date

September 2007

Volume

49

Issue

3

Start / End Page

341 / 343

Location

United States

Related Subject Headings

  • Spinal Neoplasms
  • Protective Agents
  • Osteosarcoma
  • Oncology & Carcinogenesis
  • Mesna
  • Medulloblastoma
  • Humans
  • Female
  • Drug Hypersensitivity
  • Cyclophosphamide
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Khaw, S. L., Downie, P. A., Waters, K. D., Ashley, D. M., & Heath, J. A. (2007). Adverse hypersensitivity reactions to mesna as adjunctive therapy for cyclophosphamide. Pediatr Blood Cancer, 49(3), 341–343. https://doi.org/10.1002/pbc.20617
Khaw, Seong L., Peter A. Downie, Keith D. Waters, David M. Ashley, and John A. Heath. “Adverse hypersensitivity reactions to mesna as adjunctive therapy for cyclophosphamide.Pediatr Blood Cancer 49, no. 3 (September 2007): 341–43. https://doi.org/10.1002/pbc.20617.
Khaw SL, Downie PA, Waters KD, Ashley DM, Heath JA. Adverse hypersensitivity reactions to mesna as adjunctive therapy for cyclophosphamide. Pediatr Blood Cancer. 2007 Sep;49(3):341–3.
Khaw, Seong L., et al. “Adverse hypersensitivity reactions to mesna as adjunctive therapy for cyclophosphamide.Pediatr Blood Cancer, vol. 49, no. 3, Sept. 2007, pp. 341–43. Pubmed, doi:10.1002/pbc.20617.
Khaw SL, Downie PA, Waters KD, Ashley DM, Heath JA. Adverse hypersensitivity reactions to mesna as adjunctive therapy for cyclophosphamide. Pediatr Blood Cancer. 2007 Sep;49(3):341–343.
Journal cover image

Published In

Pediatr Blood Cancer

DOI

ISSN

1545-5009

Publication Date

September 2007

Volume

49

Issue

3

Start / End Page

341 / 343

Location

United States

Related Subject Headings

  • Spinal Neoplasms
  • Protective Agents
  • Osteosarcoma
  • Oncology & Carcinogenesis
  • Mesna
  • Medulloblastoma
  • Humans
  • Female
  • Drug Hypersensitivity
  • Cyclophosphamide