Skip to main content
Journal cover image

Clinical characteristics and outcome of infective endocarditis due to Abiotrophia and Granulicatella compared to Viridans group streptococci.

Publication ,  Journal Article
Téllez, A; Ambrosioni, J; Hernández-Meneses, M; Llopis, J; Ripa, M; Chambers, ST; Holland, D; Almela, M; Fernández-Hidalgo, N; Almirante, B ...
Published in: J Infect
August 2022

OBJECTIVE: To describe the clinical characteristics and outcome of Abiotrophia and Granulicatella infective endocarditis and compare them with Viridans group streptococci infective endocarditis. METHODS: All patients in the International Collaboration on Endocarditis (ICE) - prospective cohort study (PCS) and the ICE-PLUS cohort were included (n = 8112). Data from patients with definitive or possible IE due to Abiotrophia species, Granulicatella species and Viridans group streptococci was analyzed. A propensity score (PS) analysis comparing the ABI/GRA-IE and VGS-IE groups according to a 1:2 ratio was performed. RESULTS: Forty-eight (0.64%) cases of ABI/GRA-IE and 1,292 (17.2%) VGS-IE were included in the analysis. The median age of patients with ABI/GRA-IE was lower than VGS-IE (48.1 years vs. 57.9 years; p = 0.001). Clinical features and the rate of in-hospital surgery was similar between ABI/GRA-IE and VGS-IE (52.1% vs. 45.4%; p = 0.366). Unadjusted in-hospital death was lower in ABI/GRA-IE than VGS-IE (2.1% vs. 8.8%; p = 0.003), and cumulative six-month mortality was lower in ABI/GRA-IE than VGS-IE (2.1% vs. 11.9%; p<0.001). After PS analysis, in-hospital mortality was similar in both groups, but six-month mortality was lower in the ABI/GRA IE group (2.1% vs. 10.4%; p = 0.029). CONCLUSIONS: Patients with ABI/GRA-IE were younger, had similar clinical features and rates of surgery and better prognosis than VGS-IE.

Duke Scholars

Published In

J Infect

DOI

EISSN

1532-2742

Publication Date

August 2022

Volume

85

Issue

2

Start / End Page

137 / 146

Location

England

Related Subject Headings

  • Viridans Streptococci
  • Prospective Studies
  • Middle Aged
  • Microbiology
  • Humans
  • Hospital Mortality
  • Endocarditis, Bacterial
  • Endocarditis
  • Abiotrophia
  • 3202 Clinical sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Téllez, A., Ambrosioni, J., Hernández-Meneses, M., Llopis, J., Ripa, M., Chambers, S. T., … International Collaboration on Endocarditis (ICE) Investigators, . (2022). Clinical characteristics and outcome of infective endocarditis due to Abiotrophia and Granulicatella compared to Viridans group streptococci. J Infect, 85(2), 137–146. https://doi.org/10.1016/j.jinf.2022.05.023
Téllez, Adrián, Juan Ambrosioni, Marta Hernández-Meneses, Jaume Llopis, Marco Ripa, Stephen T. Chambers, David Holland, et al. “Clinical characteristics and outcome of infective endocarditis due to Abiotrophia and Granulicatella compared to Viridans group streptococci.J Infect 85, no. 2 (August 2022): 137–46. https://doi.org/10.1016/j.jinf.2022.05.023.
Téllez A, Ambrosioni J, Hernández-Meneses M, Llopis J, Ripa M, Chambers ST, et al. Clinical characteristics and outcome of infective endocarditis due to Abiotrophia and Granulicatella compared to Viridans group streptococci. J Infect. 2022 Aug;85(2):137–46.
Téllez, Adrián, et al. “Clinical characteristics and outcome of infective endocarditis due to Abiotrophia and Granulicatella compared to Viridans group streptococci.J Infect, vol. 85, no. 2, Aug. 2022, pp. 137–46. Pubmed, doi:10.1016/j.jinf.2022.05.023.
Téllez A, Ambrosioni J, Hernández-Meneses M, Llopis J, Ripa M, Chambers ST, Holland D, Almela M, Fernández-Hidalgo N, Almirante B, Bouza E, Strahilevitz J, Hannan MM, Harkness J, Kanafani ZA, Lalani T, Lang S, Raymond N, Read K, Vinogradova T, Woods CW, Wray D, Moreno A, Chu VH, Miro JM, International Collaboration on Endocarditis (ICE) Investigators. Clinical characteristics and outcome of infective endocarditis due to Abiotrophia and Granulicatella compared to Viridans group streptococci. J Infect. 2022 Aug;85(2):137–146.
Journal cover image

Published In

J Infect

DOI

EISSN

1532-2742

Publication Date

August 2022

Volume

85

Issue

2

Start / End Page

137 / 146

Location

England

Related Subject Headings

  • Viridans Streptococci
  • Prospective Studies
  • Middle Aged
  • Microbiology
  • Humans
  • Hospital Mortality
  • Endocarditis, Bacterial
  • Endocarditis
  • Abiotrophia
  • 3202 Clinical sciences