Study of "ALS reversals": LifeTime environmental exposures (StARLiTE).

Journal Article (Journal Article)

We previously reported on a series of patients diagnosed with ALS whom had an extraordinary course defined by substantial and sustained improvement in weakness and function. For this study, twenty-five of these "ALS Reversals" completed extensive environmental exposure questionnaires. These responses were then compared to a large database of prior responses from patients with typically progressive ALS (n = 6187). The results demonstrated that the "Reversal" participants have had a diverse number of exposures with substantial heterogeneity. In general, this was similar to the control group; however, there were a few specific differences that could be further explored in future research.

Full Text

Duke Authors

Cited Authors

  • Crayle, J; Lutz, M; Raymond, J; Mehta, P; Bedlack, R

Published Date

  • February 2023

Published In

Volume / Issue

  • 24 / 1-2

Start / End Page

  • 54 - 62

PubMed ID

  • 35775279

Electronic International Standard Serial Number (EISSN)

  • 2167-9223

Digital Object Identifier (DOI)

  • 10.1080/21678421.2022.2090846


  • eng

Conference Location

  • England