An interrupted time series evaluation of a hepatitis C intervention for persons with HIV.

Published

Journal Article

Accurate HCV knowledge is lacking among high-risk groups, including people with HIV/AIDS (PLWHA). Liver disease primarily due to HCV has emerged as a serious cause of mortality among PLWHA. We used an Interrupted Time Series design to evaluate a social-ecologically based intervention for PLWHA, where an infectious disease clinic serving a six-county intervention area was monitored before (7 months) and after (17 months) intervention onset. The intervention included education of PLWHA and medical providers, HIV/HCV support groups, and adaptation of the patient chart top sheet to include HCV test information. Clinic-level outcomes were assessed prospectively every other week for 2 years by interviewing patients (n = 259) with clinic appointments on assessment days. Abrupt, gradual and delayed intervention effects were tested. Weighted regression analyses showed higher average HCV knowledge and a higher prevalence of patients reporting HCV discussion with their medical providers after intervention onset. A delayed effect was found for HCV awareness, and a gradually increasing effect was found for knowing one's HCV status. Other communities may consider adopting this intervention. Additional HCV interventions for PLWHA with HIV are needed.

Full Text

Duke Authors

Cited Authors

  • Proeschold-Bell, RJ; Hoeppner, B; Taylor, B; Cohen, S; Blouin, R; Stringfield, B; Muir, AJ

Published Date

  • November 2011

Published In

Volume / Issue

  • 15 / 8

Start / End Page

  • 1721 - 1731

PubMed ID

  • 21191643

Pubmed Central ID

  • 21191643

Electronic International Standard Serial Number (EISSN)

  • 1573-3254

Digital Object Identifier (DOI)

  • 10.1007/s10461-010-9870-1

Language

  • eng

Conference Location

  • United States