Evidence supporting secondary prevention strategies.

Journal Article (Journal Article;Review)

Currently 14 million individuals in the United States have coronary disease. Within the next 2 decades, this number is expected to increase to 21 million persons. To minimize the excessive risk of recurrent cardiac events in these people, evidence-based, cost-effective prevention strategies must be developed. This review highlights the evidence supporting commonly used means of secondary prevention and is divided into two major sections: lifestyle modifications and pharmacologic interventions. Lifestyle changes discussed include smoking cessation, especially newer pharmacologic adjuncts; the efficacy of dietary interventions; and current inroads into the treatment of depression in recurrent events. Pharmacologic innovations include reexamination of a role for warfarin; continued advances in the treatment of hyper- and dyslipidemias, new roles for beta-blockade in congestive heart failure, and finally a view of future measures, risk and targets of risk intervention.

Full Text

Duke Authors

Cited Authors

  • Blazing, MA; O'Connor, CM

Published Date

  • July 1999

Published In

Volume / Issue

  • 14 / 4

Start / End Page

  • 303 - 309

PubMed ID

  • 10448610

International Standard Serial Number (ISSN)

  • 0268-4705

Digital Object Identifier (DOI)

  • 10.1097/00001573-199907000-00005


  • eng

Conference Location

  • United States