Cytomegalovirus pericarditis: a case series and review of the literature.

Journal Article (Journal Article)

Cytomegalovirus (CMV) commonly infects both normal and immunocompromised hosts. Although it usually produces an asymptomatic infection to mild illness, CMV has the potential to significantly injure many different organs. Reports of CMV causing pericardial disease, however, are limited and documentation of infection by growth of the virus from tissue or fluid is rare. As part of a prospective trial of subxiphoid pericardial biopsy in 57 adult patients with large pericardial effusions, three culture-proven cases and one serologically confirmed case of CMV pericardial disease were discovered. Subsequently, CMV was grown from the pericardium of an infant with congenital heart disease. A review of the documented cases of CMV pericarditis is provided along with a discussion of the pathogenesis and significance of this perhaps not so uncommon disease.

Full Text

Duke Authors

Cited Authors

  • Campbell, PT; Li, JS; Wall, TC; O'Connor, CM; Van Trigt, P; Kenney, RT; Melhus, O; Corey, GR

Published Date

  • April 1995

Published In

Volume / Issue

  • 309 / 4

Start / End Page

  • 229 - 234

PubMed ID

  • 7900747

International Standard Serial Number (ISSN)

  • 0002-9629

Digital Object Identifier (DOI)

  • 10.1097/00000441-199504000-00009


  • eng

Conference Location

  • United States