Serial measurements of CT attenuation and specific gravity in experimental cerebral edema.

Journal Article (Journal Article)

Vasogenic cerebral edema was induced cryogenically in rhesus monkeys. Serial scans in both axial and coronal planes were used to study the onset, peak, and regression of edema. Progression of edema, predominantly involving the white matter, was analyzed from the postmortem distribution of a blood/brain barrier indicator (Evans blue) injected at surgery. Specific gravity was measured in fresh, unfixed specimens from both the edematous and normal hemispheres and correlated with corresponding CT attenuation values obtained before death. The drop in specific gravity closely corresponded to the decrease in CT attenuation.

Full Text

Duke Authors

Cited Authors

  • Rieth, KG; Fujiwara, K; Di Chiro, G; Klatzo, I; Brooks, RA; Johnston, GS; O'Connor, CM; Mitchell, LG

Published Date

  • May 1980

Published In

Volume / Issue

  • 135 / 2

Start / End Page

  • 343 - 348

PubMed ID

  • 6768102

International Standard Serial Number (ISSN)

  • 0033-8419

Digital Object Identifier (DOI)

  • 10.1148/radiology.135.2.6768102


  • eng

Conference Location

  • United States