The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part V. A normative study of the neuropsychological battery.
Published
Journal Article
The neuropsychological tests developed for the Consortium to Establish a Registry for Alzheimer's Disease (CERAD) are currently used to measure cognitive impairments of Alzheimer's disease (AD) in clinical investigations of this disorder. This report presents the normative information for the CERAD battery, obtained in a large sample (n = 413) of control subjects (ages 50 to 89) who were enrolled in 23 university medical centers in the United States participating in the CERAD study from 1987 to 1992. We compared separately the performance of subjects with high (> or = 12) and low (< 12) years of formal education. For many of the individual cognitive measures in the highly educated group, we observed significant age and gender effects. Only the praxis measure showed a significant age effect in the low-education group. Delayed recall, when adjusted for amount of material acquired (savings), was relatively unaffected by age, gender, and level of education. Our findings suggest that the savings scores, in particular, may be useful in distinguishing between AD and normal aging.
Full Text
Duke Authors
Cited Authors
- Welsh, KA; Butters, N; Mohs, RC; Beekly, D; Edland, S; Fillenbaum, G; Heyman, A
Published Date
- April 1, 1994
Published In
Volume / Issue
- 44 / 4
Start / End Page
- 609 - 614
PubMed ID
- 8164812
Pubmed Central ID
- 8164812
International Standard Serial Number (ISSN)
- 0028-3878
Digital Object Identifier (DOI)
- 10.1212/wnl.44.4.609
Language
- eng
Conference Location
- United States