Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Ph.D., University of Virginia 1985
• 

  Previous Appointments & Affiliations

  • Professor of Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Clinical Science Departments 2004 - 2020
  • Director, Alzheimer's Disease Research Center, Medicine, Clinical Science Departments 2006 - 2018
  • Assistant Professor in Neurology, Neurology, Behavioral Neurology, Neurology 2013 - 2015
  • Assistant Professor in Medicine, Neurology, Clinical Science Departments 1997 - 2013
  • Associate Professor of Psychological and Brain Sciences, Psychology & Neuroscience, Trinity College of Arts & Sciences 2002 - 2006
  • Associate Professor of Medical Psychology in the Department of Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Clinical Science Departments 1997 - 2003
  • Associate Professor of Psychology-Experimental, Psychology & Neuroscience, Trinity College of Arts & Sciences 1997 - 1999
  • Associate Professor of Medical Psychology in the Department of Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Clinical Science Departments 1995 - 1997
  • Assistant Professor of Medical Psychology in the Department of Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Clinical Science Departments 1987 - 1995
  • Assistant Professor of Psychology: Experimental, Psychology & Neuroscience, Trinity College of Arts & Sciences 1994 - 1995
• Recognition
• 

  In the News

  • MAY 7, 2015

    Durham Herald-Sun

    War on Alzheimer's: Durham firms lead push in treatment R&D
• Research
• 

  Selected Grants

  • Behavior and Physiology in Aging awarded by National Institutes of Health 2015 - 2025
  • Integrative modeling and dynamic prediction of Alzheimer's disease awarded by National Institutes of Health 2020 - 2025
  • Duke Creating ADRD Researchers for the Next Generation - Stimulating Access to Research in Residency Program (CARiNG-StARR)" awarded by National Institutes of Health 2020 - 2024
  • TOMMORROW DATA SHARING TO ADVANCE PRE-DEMENTIA CLINICAL TRIALS awarded by National Philanthropic Trust 2021 - 2023
  • An acoustofluidic device for diagnosing preclinical Alzheimer's disease awarded by Ascent Bio-Nano Technologies, Inc. 2022 - 2023
  • NC Registry for Brain Health Phase 3 awarded by State of North Carolina 2021 - 2023
  • Neuropsychology of Pre-dementia Alzheimer's Disease awarded by VeraSci 2018 - 2023
  • Therapeutic Effects of Exercise in Adults with Amnestic Mild Cognitive Impairment ("EXERT") awarded by University of California - San Diego 2016 - 2022
  • Impact of Disclosing Amyloid Imaging Results to Cognitively Normal Individuals--Reveal Scan Admin Supplement awarded by Brigham and Women's Hospital 2020 - 2021
  • NC Registry for Brain Health Phase 2 awarded by State of North Carolina 2019 - 2021
  • An acoustofluidic device for diagnosing preclinical Alzheimer's Disease awarded by Ascent Bio-Nano Technologies, Inc. 2020 - 2021
  • White Matter Damage in Subconcussive Blast Exposure awarded by National Institutes of Health 2014 - 2021
  • Integrative modeling and dynamic prediction of Alzheimer's disease awarded by National Institutes of Health 2019 - 2020
  • Shared genetic, epigenetic, and transcriptomic profiles between AD and PTSD: molecular insights into the heterogeneity of neuropsychiatric symptoms in Alzheimers Disease awarded by National Institutes of Health 2018 - 2020
  • Metabolic Signatures Underlying Vascular Risk Factors for Alzheimer-type Dementias awarded by National Institutes of Health 2015 - 2020
  • NC Registry for Brain Health awarded by State of North Carolina 2018 - 2020
  • Impact of Disclosing Amyloid Imaging Results to Cognitively Normal Individuals awarded by Brigham and Women's Hospital 2015 - 2020
  • A Double-Blind, Placebo Controlled Study to Evaluate the Safety and Efficacy of Two Doses of T3D-959 in Subjects with Mild to Moderate Alzheimer's Disease awarded by T3D Therapeutics, Inc. 2018 - 2019
  • Metabolic Networks and Pathways in Alzheimer's Disease awarded by National Institutes of Health 2014 - 2019
  • Innovating Tablet-Based Cognitive Assessment for CNS Disorders of Aging awarded by NeuroCog Trials 2016 - 2018
  • Lifestyle, CVD Risk and Cognitive Impairment awarded by National Institutes of Health 2011 - 2018
  • Bryan ADRC Brain Bank awarded by Cofactor Genomics, Inc. 2016 - 2017
  • A Randomized,Cross-Over,Controlled Feasibililty and Validation Study of a Self-Adminstered Memory Screening Test with Automated Reporting(SAMSTAR) inNormal Control subjects and Subjects with MCI, age 55-84 awarded by Janssen Research & Development, LLC 2015 - 2016
  • North Carolina Regional Consortium for Brain Health in Aging awarded by Alzheimers North Carolina, Inc 2013 - 2015
  • Behavior And Physiology In Aging awarded by National Institutes of Health 1999 - 2015
  • Emotion Regulation in Late-Life Depression: Effectiveness and Neural Mechanisms awarded by National Institutes of Health 2009 - 2015
  • ADCC Genomic Medical Approach to MCI and Dementia awarded by National Institutes of Health 2006 - 2013
  • Cognitive Endophenotypes for Genetic Studies of Alzheimer's Disease awarded by National Institutes of Health 2007 - 2012
  • Geriatric Depression: Risk Factors for Adverse Outcomes awarded by National Institutes of Health 1995 - 2012
  • FMRI: Prediction of Mild Cognitive Impairment in Geriatric Depression awarded by National Institutes of Health 2008 - 2012
  • Metabolic Signatures for Alzheimer's Disease awarded by National Institutes of Health 2007 - 2011
  • Epidemiology of Dementia in Cache County, Utah (Bridge-Funding Request) awarded by National Institutes of Health 2002 - 2011
  • Epidemiology of Dementia in Cache County, Utah awarded by National Institutes of Health 1994 - 2011
  • PeriOperative Interventional Neuroprotection Trial POINT awarded by National Institutes of Health 2001 - 2008
  • Same awarded by National Institutes of Health 1989 - 2008
  • Treatment Outcomes of Vascular Depression awarded by National Institutes of Health 2001 - 2007
  • An Integrated Genomic approach to Alzheimer Disease awarded by National Institutes of Health 2002 - 2007
  • Alzheimer's Disease Research Center awarded by National Institutes of Health 1985 - 2006
  • Epidemiology Of Alzheimer'S Dementia In Cache County Utah awarded by National Institutes of Health 1994 - 1999
  • Alzheimer'S Disease Research Center awarded by National Institutes of Health 1985 - 1999
  • Alzheimer'S Disease Research Center awarded by National Institutes of Health 1985 - 1999
  • Alzheimer'S Disease Research Center awarded by National Institutes of Health 1985 - 1999
  • Alzheimer'S Disease Research Center awarded by National Institutes of Health 1985 - 1999
  • Neuropsychological Study Of Alzheimer'S Disease awarded by National Institutes of Health 1992 - 1998
  • Genetic Epidemiolgy Of Alzheimer Disease In Twins awarded by National Institutes of Health 1996 - 1998
  • Neuropsychological Study Of Alzheimer'S Diseases awarded by National Institutes of Health 1992 - 1997
  • Genetic Epidemiology Alzheimer Disease In Twins awarded by National Institutes of Health 1993 - 1995
• 

  External Relationships

  • Biogen
  • Center for Neurodegeneration and Translational Neuroscience (CNTN) COBRE
  • Dementia Alliance of NC
  • Genentech Roche
  • Guilford Publications
  • Pointer Study
  • WCG VeraSci
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Blair, Emilie M., Bailey K. Reale, Darin B. Zahuranec, Jane Forman, Kenneth M. Langa, Bruno J. Giordani, Brenda L. Plassman, et al. “Influence of mild cognitive impairment on patient and care partner decision-making for acute ischemic stroke.” J Stroke Cerebrovasc Dis 32, no. 6 (June 2023): 107068. https://doi.org/10.1016/j.jstrokecerebrovasdis.2023.107068.
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    • Largent, Emily A., Sarah Walter, Nancy Childs, Penny A. Dacks, Shana Dodge, Hana Florian, Jonathan Jackson, et al. “Putting participants and study partners FIRST when clinical trials end early.” Alzheimers Dement 18, no. 12 (December 2022): 2736–46. https://doi.org/10.1002/alz.12732.
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    • Levine, Deborah A., Andrzej T. Galecki, Brenda L. Plassman, Angela Fagerlin, Lauren P. Wallner, Kenneth M. Langa, Rachael T. Whitney, et al. “The Association Between Mild Cognitive Impairment Diagnosis and Patient Treatment Preferences: a Survey of Older Adults.” Journal of General Internal Medicine 37, no. 8 (June 2022): 1925–34. https://doi.org/10.1007/s11606-021-06839-w.
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    • Hao, Nanjing, Zeyu Wang, Pengzhan Liu, Ryan Becker, Shujie Yang, Kaichun Yang, Zhichao Pei, et al. “Acoustofluidic multimodal diagnostic system for Alzheimer's disease.” Biosens Bioelectron 196 (January 15, 2022): 113730. https://doi.org/10.1016/j.bios.2021.113730.
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    • Kimmel, Hannah J., Deborah A. Levine, Rachael T. Whitney, Jane Forman, Brenda L. Plassman, Angela Fagerlin, Kathleen Anne Welsh-Bohmer, et al. “A Mixed-Methods Study of the Impact of Mild Cognitive Impairment Diagnosis on Patient and Care Partner Perception of Health Risks.” J Alzheimers Dis 85, no. 3 (2022): 1175–87. https://doi.org/10.3233/JAD-215155.
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    • Schneider, L. S., D. A. Bennett, M. R. Farlow, E. R. Peskind, M. A. Raskind, M. Sano, Y. Stern, et al. “Adjudicating Mild Cognitive Impairment Due to Alzheimer's Disease as a Novel Endpoint Event in the TOMMORROW Prevention Clinical Trial.” J Prev Alzheimers Dis 9, no. 4 (2022): 625–34. https://doi.org/10.14283/jpad.2022.72.
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    • Shadyab, Aladdin H., Andrea Z. LaCroix, Howard H. Feldman, Christopher H. van Dyck, Ozioma C. Okonkwo, Steven P. Tam, J Kaci Fairchild, et al. “Recruitment of a multi-site randomized controlled trial of aerobic exercise for older adults with amnestic mild cognitive impairment: The EXERT trial.” Alzheimers Dement 17, no. 11 (November 2021): 1808–17. https://doi.org/10.1002/alz.12401.
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    • Clausen, Ashley N., Heather C. Bouchard, Heather C. VA Mid-Atlantic MIRECC Workgroup, Kathleen A. Welsh-Bohmer, and Rajendra A. Morey. “Assessment of Neuropsychological Function in Veterans With Blast-Related Mild Traumatic Brain Injury and Subconcussive Blast Exposure.” Front Psychol 12 (2021): 686330. https://doi.org/10.3389/fpsyg.2021.686330.
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    • Cocroft, Shelytia, Kathleen A. Welsh-Bohmer, Brenda L. Plassman, Marianne Chanti-Ketterl, Henry Edmonds, Lisa Gwyther, Michelle McCart, Heather MacDonald, Guy Potter, and James R. Burke. “Racially diverse participant registries to facilitate the recruitment of African Americans into presymptomatic Alzheimer's disease studies.” Alzheimers Dement 16, no. 8 (August 2020): 1107–14. https://doi.org/10.1002/alz.12048.
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    • Blumenthal, James A., Patrick J. Smith, Stephanie Mabe, Alan Hinderliter, Kathleen Welsh-Bohmer, Jeffrey N. Browndyke, P Murali Doraiswamy, et al. “Longer Term Effects of Diet and Exercise on Neurocognition: 1-Year Follow-up of the ENLIGHTEN Trial.” J Am Geriatr Soc 68, no. 3 (March 2020): 559–68. https://doi.org/10.1111/jgs.16252.
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    • Dodge, Hiroko H., Felicia C. Goldstein, Nicole I. Wakim, Tamar Gefen, Merilee Teylan, Kwun C. G. Chan, Walter A. Kukull, et al. “Differentiating among stages of cognitive impairment in aging: Version 3 of the Uniform Data Set (UDS) neuropsychological test battery and MoCA index scores.” Alzheimers Dement (N Y) 6, no. 1 (2020): e12103. https://doi.org/10.1002/trc2.12103.
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    • Smith, Patrick J., Stephanie M. Mabe, Andrew Sherwood, P Murali Doraiswamy, Kathleen A. Welsh-Bohmer, James R. Burke, William E. Kraus, et al. “Metabolic and Neurocognitive Changes Following Lifestyle Modification: Examination of Biomarkers from the ENLIGHTEN Randomized Clinical Trial.” J Alzheimers Dis 77, no. 4 (2020): 1793–1803. https://doi.org/10.3233/JAD-200374.
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    • Mathew, Joseph P., Kathleen A. Welsh-Bohmer, and Mark F. Newman. “Nomenclature for Perioperative Cognitive Disorders: Comment.” Anesthesiology 131, no. 2 (August 2019): 443–44. https://doi.org/10.1097/ALN.0000000000002831.
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    • Klinger, Rebecca Y., Mary Cooter, Tiffany Bisanar, Niccolò Terrando, Miles Berger, Mihai V. Podgoreanu, Mark Stafford-Smith, Mark F. Newman, Joseph P. Mathew, and Joseph P. Neurologic Outcomes Research Group of the Duke Heart Center. “Intravenous Lidocaine Does Not Improve Neurologic Outcomes after Cardiac Surgery: A Randomized Controlled Trial.” Anesthesiology 130, no. 6 (June 2019): 958–70. https://doi.org/10.1097/ALN.0000000000002668.
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    • Blumenthal, James A., Patrick J. Smith, Stephanie Mabe, Alan Hinderliter, Pao-Hwa Lin, Lawrence Liao, Kathleen A. Welsh-Bohmer, et al. “Lifestyle and neurocognition in older adults with cognitive impairments: A randomized trial.” Neurology 92, no. 3 (January 15, 2019): e212–23. https://doi.org/10.1212/WNL.0000000000006784.
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    • Burns, Daniel K., Carl Chiang, Kathleen A. Welsh-Bohmer, Stephen K. Brannan, Meredith Culp, Janet O’Neil, Grant Runyan, et al. “The TOMMORROW study: Design of an Alzheimer's disease delay-of-onset clinical trial.” Alzheimers Dement (N Y) 5 (2019): 661–70. https://doi.org/10.1016/j.trci.2019.09.010.
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    • Gauthier, S., J. Alam, H. Fillit, T. Iwatsubo, H. Liu-Seifert, M. Sabbagh, S. Salloway, et al. “Combination Therapy for Alzheimer's Disease: Perspectives of the EU/US CTAD Task Force.” J Prev Alzheimers Dis 6, no. 3 (2019): 164–68. https://doi.org/10.14283/jpad.2019.12.
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    • Knodt, Annchen R., James R. Burke, Kathleen A. Welsh-Bohmer, Brenda L. Plassman, Daniel K. Burns, Stephen K. Brannan, Michael Kukulka, Jingtao Wu, and Ahmad R. Hariri. “Effects of pioglitazone on mnemonic hippocampal function: A blood oxygen level-dependent functional magnetic resonance imaging study in elderly adults.” Alzheimers Dement (N Y) 5 (2019): 254–63. https://doi.org/10.1016/j.trci.2019.05.004.
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    • Smith, Patrick J., Stephanie Mabe, Andrew Sherwood, Michael A. Babyak, P Murali Doraiswamy, Kathleen A. Welsh-Bohmer, William Kraus, James Burke, Alan Hinderliter, and James A. Blumenthal. “Association Between Insulin Resistance, Plasma Leptin, and Neurocognition in Vascular Cognitive Impairment.” J Alzheimers Dis 71, no. 3 (2019): 921–29. https://doi.org/10.3233/JAD-190569.
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    • Tsui-Caldwell, Y. H. W., T. J. Farrer, Z. McDonnell, Z. Christensen, C. Finuf, E. D. Bigler, J. T. Tschanz, M. C. Norton, and K. A. Welsh-Bohmer. “MRI Clinical Ratings and Cognitive Function in a Cross-Sectional Population Study of Dementia: The Cache County Memory Study.” J Prev Alzheimers Dis 6, no. 2 (2019): 100–107. https://doi.org/10.14283/jpad.2019.1.
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    • Deming, Yuetiva, Logan Dumitrescu, Lisa L. Barnes, Madhav Thambisetty, Brian Kunkle, Katherine A. Gifford, William S. Bush, et al. “Sex-specific genetic predictors of Alzheimer's disease biomarkers.” Acta Neuropathol 136, no. 6 (December 2018): 857–72. https://doi.org/10.1007/s00401-018-1881-4.
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    • Hohman, Timothy J., Logan Dumitrescu, Lisa L. Barnes, Madhav Thambisetty, Gary Beecham, Brian Kunkle, Katherine A. Gifford, et al. “Sex-Specific Association of Apolipoprotein E With Cerebrospinal Fluid Levels of Tau.” Jama Neurol 75, no. 8 (August 1, 2018): 989–98. https://doi.org/10.1001/jamaneurol.2018.0821.
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    • Browndyke, Jeffrey N., Miles Berger, Patrick J. Smith, Todd B. Harshbarger, Zachary A. Monge, Viral Panchal, Tiffany L. Bisanar, et al. “Task-related changes in degree centrality and local coherence of the posterior cingulate cortex after major cardiac surgery in older adults.” Hum Brain Mapp 39, no. 2 (February 2018): 985–1003. https://doi.org/10.1002/hbm.23898.
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    • Atkins, A. S., A. Khan, D. Ulshen, A. Vaughan, D. Balentin, H. Dickerson, L. E. Liharska, B. Plassman, K. Welsh-Bohmer, and R. S. E. Keefe. “Assessment of Instrumental Activities of Daily Living in Older Adults with Subjective Cognitive Decline Using the Virtual Reality Functional Capacity Assessment Tool (VRFCAT).” J Prev Alzheimers Dis 5, no. 4 (2018): 216–34. https://doi.org/10.14283/jpad.2018.28.
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    • Morrison, Randall L., Huiling Pei, Gerald Novak, Daniel I. Kaufer, Kathleen A. Welsh-Bohmer, Stephen Ruhmel, and Vaibhav A. Narayan. “A computerized, self-administered test of verbal episodic memory in elderly patients with mild cognitive impairment and healthy participants: A randomized, crossover, validation study.” Alzheimers Dement (Amst) 10 (2018): 647–56. https://doi.org/10.1016/j.dadm.2018.08.010.
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    • Peloso, G. M., S. J. van der Lee, R. Sims, A. C. Naj, C. Bellenguez, N. Badarinarayan, J. Jakobsdottir, et al. “Genetically elevated high-density lipoprotein cholesterol through the cholesteryl ester transfer protein gene does not associate with risk of Alzheimer's disease.” Alzheimer’S and Dementia: Diagnosis, Assessment and Disease Monitoring 10 (January 1, 2018): 595–98. https://doi.org/10.1016/j.dadm.2018.08.008.
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    • Romero, Heather R., Andreas U. Monsch, Kathleen M. Hayden, Brenda L. Plassman, Alexandra S. Atkins, Richard S. E. Keefe, Shyama Brewster, et al. “TOMMORROW neuropsychological battery: German language validation and normative study.” Alzheimers Dement (N Y) 4 (2018): 314–23. https://doi.org/10.1016/j.trci.2018.06.009.
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    • Weintraub, Sandra, Lilah Besser, Hiroko H. Dodge, Merilee Teylan, Steven Ferris, Felicia C. Goldstein, Bruno Giordani, et al. “Version 3 of the Alzheimer Disease Centers' Neuropsychological Test Battery in the Uniform Data Set (UDS).” Alzheimer Dis Assoc Disord 32, no. 1 (2018): 10–17. https://doi.org/10.1097/WAD.0000000000000223.
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    • Weintraub, Sandra, Maria C. Carrillo, Sarah Tomaszewski Farias, Terry E. Goldberg, James A. Hendrix, Judith Jaeger, David S. Knopman, et al. “Measuring cognition and function in the preclinical stage of Alzheimer's disease.” Alzheimers Dement (N Y) 4 (2018): 64–75. https://doi.org/10.1016/j.trci.2018.01.003.
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    • Whitson, Heather E., Guy G. Potter, Jody A. Feld, Brenda L. Plassman, Kelly Reynolds, Richard Sloane, and Kathleen A. Welsh-Bohmer. “Dual-Task Gait and Alzheimer's Disease Genetic Risk in Cognitively Normal Adults: A Pilot Study.” J Alzheimers Dis 64, no. 4 (2018): 1137–48. https://doi.org/10.3233/JAD-180016.
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    • Sims, Rebecca, Sven J. van der Lee, Adam C. Naj, Céline Bellenguez, Nandini Badarinarayan, Johanna Jakobsdottir, Brian W. Kunkle, et al. “Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.” Nat Genet 49, no. 9 (September 2017): 1373–84. https://doi.org/10.1038/ng.3916.
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    • Jun, Gyungah R., Jaeyoon Chung, Jesse Mez, Robert Barber, Gary W. Beecham, David A. Bennett, Joseph D. Buxbaum, et al. “Transethnic genome-wide scan identifies novel Alzheimer's disease loci.” Alzheimers Dement 13, no. 7 (July 2017): 727–38. https://doi.org/10.1016/j.jalz.2016.12.012.
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    • Blumenthal, James A., Patrick J. Smith, Stephanie Mabe, Alan Hinderliter, Kathleen Welsh-Bohmer, Jeffrey N. Browndyke, Pao-Hwa Lin, et al. “Lifestyle and Neurocognition in Older Adults With Cardiovascular Risk Factors and Cognitive Impairment.” Psychosom Med 79, no. 6 (2017): 719–27. https://doi.org/10.1097/PSY.0000000000000474.
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    • Browndyke, Jeffrey N., Miles Berger, Todd B. Harshbarger, Patrick J. Smith, William White, Tiffany L. Bisanar, John H. Alexander, et al. “Resting-State Functional Connectivity and Cognition After Major Cardiac Surgery in Older Adults without Preoperative Cognitive Impairment: Preliminary Findings.” J Am Geriatr Soc 65, no. 1 (January 2017): e6–12. https://doi.org/10.1111/jgs.14534.
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    • Lutz, Michael W., Donna Crenshaw, Kathleen A. Welsh-Bohmer, Daniel K. Burns, and Allen D. Roses. “New Genetic Approaches to AD: Lessons from APOE-TOMM40 Phylogenetics.” Curr Neurol Neurosci Rep 16, no. 5 (May 2016): 48. https://doi.org/10.1007/s11910-016-0643-8.
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    • Ridge, Perry G., Kaitlyn B. Hoyt, Kevin Boehme, Shubhabrata Mukherjee, Paul K. Crane, Jonathan L. Haines, Richard Mayeux, et al. “Assessment of the genetic variance of late-onset Alzheimer's disease.” Neurobiol Aging 41 (May 2016): 200.e13-200.e20. https://doi.org/10.1016/j.neurobiolaging.2016.02.024.
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    • Weninger, Stacie, Maria C. Carrillo, Billy Dunn, Paul S. Aisen, Randall J. Bateman, Joanne D. Kotz, Jessica B. Langbaum, et al. “Collaboration for Alzheimer's Prevention: Principles to guide data and sample sharing in preclinical Alzheimer's disease trials.” Alzheimers Dement 12, no. 5 (May 2016): 631–32. https://doi.org/10.1016/j.jalz.2016.04.001.
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    • Perry, David C., Virginia E. Sturm, Matthew J. Peterson, Carl F. Pieper, Thomas Bullock, Bradley F. Boeve, Bruce L. Miller, et al. “Association of traumatic brain injury with subsequent neurological and psychiatric disease: a meta-analysis.” J Neurosurg 124, no. 2 (February 2016): 511–26. https://doi.org/10.3171/2015.2.JNS14503.
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    • Foster, Chris M., Donna Rose Addis, Jaclyn H. Ford, Daniel I. Kaufer, James R. Burke, Jeffrey N. Browndyke, Kathleen A. Welsh-Bohmer, and Kelly S. Giovanello. “Prefrontal contributions to relational encoding in amnestic mild cognitive impairment.” Neuroimage Clin 11 (2016): 158–66. https://doi.org/10.1016/j.nicl.2016.01.008.
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    • Jun, G., C. A. Ibrahim-Verbaas, M. Vronskaya, J. -. C. Lambert, J. Chung, A. C. Naj, B. W. Kunkle, et al. “A novel Alzheimer disease locus located near the gene encoding tau protein.” Mol Psychiatry 21, no. 1 (January 2016): 108–17. https://doi.org/10.1038/mp.2015.23.
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    • Karch, Celeste M., Lubov A. Ezerskiy, Sarah Bertelsen, Sarah Alzheimer’s Disease Genetics Consortium (ADGC), and Alison M. Goate. “Alzheimer's Disease Risk Polymorphisms Regulate Gene Expression in the ZCWPW1 and the CELF1 Loci.” Plos One 11, no. 2 (2016): e0148717. https://doi.org/10.1371/journal.pone.0148717.
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    • Lutz, Michael W., Scott S. Sundseth, Daniel K. Burns, Ann M. Saunders, Kathleen M. Hayden, James R. Burke, Kathleen A. Welsh-Bohmer, and Allen D. Roses. “A Genetics-based Biomarker Risk Algorithm for Predicting Risk of Alzheimer's Disease.” Alzheimers Dement (N Y) 2, no. 1 (January 1, 2016): 30–44. https://doi.org/10.1016/j.trci.2015.12.002.
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    • Monsell, Sarah E., Hiroko H. Dodge, Xiao-Hua Zhou, Yunqi Bu, Lilah M. Besser, Charles Mock, Stephen E. Hawes, Walter A. Kukull, Sandra Weintraub, and Sandra Neuropsychology Work Group Advisory to the Clinical Task Force. “Results From the NACC Uniform Data Set Neuropsychological Battery Crosswalk Study.” Alzheimer Dis Assoc Disord 30, no. 2 (2016): 134–39. https://doi.org/10.1097/WAD.0000000000000111.
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    • Reiman, Eric M., Jessica B. Langbaum, Pierre N. Tariot, Francisco Lopera, Randall J. Bateman, John C. Morris, Reisa A. Sperling, et al. “CAP--advancing the evaluation of preclinical Alzheimer disease treatments.” Nat Rev Neurol 12, no. 1 (January 2016): 56–61. https://doi.org/10.1038/nrneurol.2015.177.
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    • Mukherjee, Shubhabrata, Stefan Walter, John S. K. Kauwe, Andrew J. Saykin, David A. Bennett, Eric B. Larson, Paul K. Crane, et al. “Genetically predicted body mass index and Alzheimer's disease-related phenotypes in three large samples: Mendelian randomization analyses.” Alzheimers Dement 11, no. 12 (December 2015): 1439–51. https://doi.org/10.1016/j.jalz.2015.05.015.
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    • Ghani, Mahdi, Christiane Reitz, Rong Cheng, Badri Narayan Vardarajan, Gyungah Jun, Christine Sato, Adam Naj, et al. “Association of Long Runs of Homozygosity With Alzheimer Disease Among African American Individuals.” Jama Neurol 72, no. 11 (November 2015): 1313–23. https://doi.org/10.1001/jamaneurol.2015.1700.
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    • Mistridis, P., S. C. Egli, G. L. Iverson, M. Berres, K. Willmes, K. A. Welsh-Bohmer, and A. U. Monsch. “Considering the base rates of low performance in cognitively healthy older adults improves the accuracy to identify neurocognitive impairment with the Consortium to Establish a Registry for Alzheimer’s Disease-Neuropsychological Assessment Battery (CERAD-NAB).” European Archives of Psychiatry and Clinical Neuroscience 265, no. 5 (August 12, 2015): 407–17. https://doi.org/10.1007/s00406-014-0571-z.
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    • Cao, Lin, Sean D. Pokorney, Kathleen Hayden, Kathleen Welsh-Bohmer, and L Kristin Newby. “Cognitive Function: Is There More to Anticoagulation in Atrial Fibrillation Than Stroke?” J Am Heart Assoc 4, no. 8 (August 3, 2015): e001573. https://doi.org/10.1161/JAHA.114.001573.
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    • Mistridis, Panagiota, Simone C. Egli, Grant L. Iverson, Manfred Berres, Klaus Willmes, Kathleen A. Welsh-Bohmer, and Andreas U. Monsch. “Considering the base rates of low performance in cognitively healthy older adults improves the accuracy to identify neurocognitive impairment with the Consortium to Establish a Registry for Alzheimer's Disease-Neuropsychological Assessment Battery (CERAD-NAB).” Eur Arch Psychiatry Clin Neurosci 265, no. 5 (August 2015): 407–17. https://doi.org/10.1007/s00406-014-0571-z.
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    • Østergaard, Søren D., Shubhabrata Mukherjee, Stephen J. Sharp, Petroula Proitsi, Luca A. Lotta, Felix Day, John R. B. Perry, et al. “Associations between Potentially Modifiable Risk Factors and Alzheimer Disease: A Mendelian Randomization Study.” Plos Med 12, no. 6 (June 2015): e1001841. https://doi.org/10.1371/journal.pmed.1001841.
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    • Smith, Patrick J., James A. Blumenthal, Benson M. Hoffman, Harris Cooper, Timothy A. Strauman, Kathleen Welsh-Bohmer, Jeffrey N. Browndyke, and Andrew Sherwood. “Aerobic exercise and neurocognitive performance: a meta-analytic review of randomized controlled trials.” Psychosom Med 72, no. 3 (April 2010): 239–52. https://doi.org/10.1097/PSY.0b013e3181d14633.
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    • Sheline, Yvette I., Carl F. Pieper, Deanna M. Barch, Kathleen Welsh-Bohmer, Robert C. McKinstry, James R. MacFall, Gina D’Angelo, et al. “Support for the vascular depression hypothesis in late-life depression: results of a 2-site, prospective, antidepressant treatment trial.” Arch Gen Psychiatry 67, no. 3 (March 2010): 277–85. https://doi.org/10.1001/archgenpsychiatry.2009.204.
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    • Chuang, Yi-Fang, Kathleen M. Hayden, Maria C. Norton, Joann Tschanz, John C. S. Breitner, Kathleen A. Welsh-Bohmer, and Peter P. Zandi. “Association between APOE epsilon4 allele and vascular dementia: The Cache County study.” Dement Geriatr Cogn Disord 29, no. 3 (2010): 248–53. https://doi.org/10.1159/000285166.
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    • Welsh-Bohmer, K. A., B. L. Plassman, and K. M. Hayden. “Genetic and environmental contributions to cognitive decline in aging and Alzheimer's disease.” Annual Review of Gerontology and Geriatrics 30, no. 1 (January 1, 2010): 81–114. https://doi.org/10.1891/0198-8794.30.81.
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    • Heinzen, Erin L., Anna C. Need, Kathleen M. Hayden, Ornit Chiba-Falek, Allen D. Roses, Warren J. Strittmatter, James R. Burke, Christine M. Hulette, Kathleen A. Welsh-Bohmer, and David B. Goldstein. “Genome-wide scan of copy number variation in late-onset Alzheimer's disease.” J Alzheimers Dis 19, no. 1 (2010): 69–77. https://doi.org/10.3233/JAD-2010-1212.
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    • Hayden, Kathleen M., Peter P. Zandi, Nancy A. West, Joann T. Tschanz, Maria C. Norton, Chris Corcoran, John C. S. Breitner, Kathleen A. Welsh-Bohmer, and Kathleen A. Cache County Study Group. “Effects of family history and apolipoprotein E epsilon4 status on cognitive decline in the absence of Alzheimer dementia: the Cache County Study.” Arch Neurol 66, no. 11 (November 2009): 1378–83. https://doi.org/10.1001/archneurol.2009.237.
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    • Linnertz, Colton, Laura Saucier, Dongliang Ge, Kenneth D. Cronin, James R. Burke, Jeffrey N. Browndyke, Christine M. Hulette, Kathleen A. Welsh-Bohmer, and Ornit Chiba-Falek. “Genetic regulation of alpha-synuclein mRNA expression in various human brain tissues.” Plos One 4, no. 10 (October 16, 2009): e7480. https://doi.org/10.1371/journal.pone.0007480.
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    • Potter, G. G., W. D. Taylor, D. R. McQuoid, D. C. Steffens, K. A. Welsh-Bohmer, and K. R. R. Krishnan. “The COMT Val158Met polymorphism and cognition in depressed and nondepressed older adults.” Int J Geriatr Psychiatry 24, no. 10 (October 2009): 1127–33. https://doi.org/10.1002/gps.2235.
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    • Levin, Edward D., Michael Aschner, Ulrike Heberlein, Douglas Ruden, Kathleen A. Welsh-Bohmer, Selena Bartlett, Karen Berger, et al. “Genetic aspects of behavioral neurotoxicology.” Neurotoxicology 30, no. 5 (September 2009): 741–53. https://doi.org/10.1016/j.neuro.2009.07.014.
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    • Norton, Maria C., Kathleen W. Piercy, Peter V. Rabins, Robert C. Green, John C. S. Breitner, Truls Ostbye, Christopher Corcoran, Kathleen A. Welsh-Bohmer, Constantine G. Lyketsos, and Joann T. Tschanz. “Caregiver-recipient closeness and symptom progression in Alzheimer disease. The Cache County Dementia Progression Study.” J Gerontol B Psychol Sci Soc Sci 64, no. 5 (September 2009): 560–68. https://doi.org/10.1093/geronb/gbp052.
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    • Hulette, Christine M., John F. Ervin, Yvette Edmonds, Samantha Antoine, Nicolas Stewart, Mari H. Szymanski, Kathleen M. Hayden, Carl F. Pieper, James R. Burke, and Kathleen A. Welsh-Bohmer. “Cerebrovascular smooth muscle actin is increased in nondemented subjects with frequent senile plaques at autopsy: implications for the pathogenesis of Alzheimer disease.” J Neuropathol Exp Neurol 68, no. 4 (April 2009): 417–24. https://doi.org/10.1097/NEN.0b013e31819e6334.
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    • Potter, G. G., D. R. McQuoid, D. C. Steffens, K. A. Welsh-Bohmer, and K. R. R. Krishnan. “Neuropsychological correlates of magnetic resonance imaging-defined subcortical ischemic depression.” Int J Geriatr Psychiatry 24, no. 3 (March 2009): 219–25. https://doi.org/10.1002/gps.2093.
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    • Welsh-Bohmer, Kathleen A., and Charles L. White. “Alzheimer disease: what changes in the brain cause dementia?” Neurology 72, no. 4 (January 27, 2009): e21. https://doi.org/10.1212/01.wnl.0000343818.11392.d9.
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    • Welsh-Bohmer, Katheen A., Truls Ostbye, Linda Sanders, Carl F. Pieper, Kathleen M. Hayden, JoAnn T. Tschanz, Maria C. Norton, and Maria C. Cache Country Study Group. “Neuropsychological performance in advanced age: influences of demographic factors and Apolipoprotein E: findings from the Cache County Memory Study.” Clin Neuropsychol 23, no. 1 (January 2009): 77–99. https://doi.org/10.1080/13854040801894730.
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    • Heinzen, Erin L., Dongliang Ge, Kenneth D. Cronin, Jessica M. Maia, Kevin V. Shianna, Willow N. Gabriel, Kathleen A. Welsh-Bohmer, Christine M. Hulette, Thomas N. Denny, and David B. Goldstein. “Tissue-specific genetic control of splicing: implications for the study of complex traits.” Plos Biol 6, no. 12 (December 23, 2008): e1. https://doi.org/10.1371/journal.pbio.1000001.
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    • Rosenberg, P. B., M. M. Mielke, J. Tschanz, L. Cook, Chris Corcoran, K. M. Hayden, M. Norton, et al. “Effects of cardiovascular medications on rate of functional decline in Alzheimer disease.” Am J Geriatr Psychiatry 16, no. 11 (November 2008): 883–92. https://doi.org/10.1097/JGP.0b013e318181276a.
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    • Welsh-Bohmer, K. “Neuropsychological characterization of dementia patients.” Primary Psychiatry 15, no. 10 SUPPL. 6 (October 1, 2008): 10–13.
    • Welsh-Bohmer, Kathleen. “Neuropsychological characterization of dementia patients.” Cns Spectr 13, no. 10 Suppl 16 (October 2008): 10–13. https://doi.org/10.1017/s1092852900026973.
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    • Story, Tyler J., Guy G. Potter, Deborah K. Attix, Kathleen A. Welsh-Bohmer, and David C. Steffens. “Neurocognitive correlates of response to treatment in late-life depression.” Am J Geriatr Psychiatry 16, no. 9 (September 2008): 752–59. https://doi.org/10.1097/JGP.0b013e31817e739a.
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    • Carney, R. M., M. A. Slifer, P. I. Lin, P. C. Gaskell, W. K. Scott, C. F. Potocky, C. M. Hulette, et al. “Longitudinal follow-up of late-onset Alzheimer disease families.” Am J Med Genet B Neuropsychiatr Genet 147B, no. 5 (July 5, 2008): 571–78. https://doi.org/10.1002/ajmg.b.30590.
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    • Szekely, C. A., R. C. Green, J. C. S. Breitner, T. Østbye, A. S. Beiser, M. M. Corrada, H. H. Dodge, et al. “No advantage of A beta 42-lowering NSAIDs for prevention of Alzheimer dementia in six pooled cohort studies.” Neurology 70, no. 24 (June 10, 2008): 2291–98. https://doi.org/10.1212/01.wnl.0000313933.17796.f6.
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    • Browndyke, Jeffrey N., James Paskavitz, Lawrence H. Sweet, Ronald A. Cohen, Karen A. Tucker, Kathleen A. Welsh-Bohmer, James R. Burke, and Donald E. Schmechel. “Neuroanatomical correlates of malingered memory impairment: event-related fMRI of deception on a recognition memory task.” Brain Inj 22, no. 6 (June 2008): 481–89. https://doi.org/10.1080/02699050802084894.
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    • Treiber, Katherine A., Constantine G. Lyketsos, Chris Corcoran, Martin Steinberg, Maria Norton, Robert C. Green, Peter Rabins, et al. “Vascular factors and risk for neuropsychiatric symptoms in Alzheimer's disease: the Cache County Study.” Int Psychogeriatr 20, no. 3 (June 2008): 538–53. https://doi.org/10.1017/S1041610208006704.
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    • Hallam, Bradley J., Warren S. Brown, Chris Ross, J Galen Buckwalter, Erin D. Bigler, Joann T. Tschanz, Maria C. Norton, Kathleen A. Welsh-Bohmer, and John C. S. Breitner. “Regional atrophy of the corpus callosum in dementia.” J Int Neuropsychol Soc 14, no. 3 (May 2008): 414–23. https://doi.org/10.1017/S1355617708080533.
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    • Norton, Maria C., Archana Singh, Ingmar Skoog, Christopher Corcoran, Joann T. Tschanz, Peter P. Zandi, John C. S. Breitner, Kathleen A. Welsh-Bohmer, David C. Steffens, and David C. Cache County Investigators. “Church attendance and new episodes of major depression in a community study of older adults: the Cache County Study.” J Gerontol B Psychol Sci Soc Sci 63, no. 3 (May 2008): P129–37. https://doi.org/10.1093/geronb/63.3.p129.
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    • Fotuhi, Majid, Peter P. Zandi, Kathleen M. Hayden, Ara S. Khachaturian, Christine A. Szekely, Heidi Wengreen, Ronald G. Munger, et al. “Better cognitive performance in elderly taking antioxidant vitamins E and C supplements in combination with nonsteroidal anti-inflammatory drugs: the Cache County Study.” Alzheimers Dement 4, no. 3 (May 2008): 223–27. https://doi.org/10.1016/j.jalz.2008.01.004.
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    • Martini, Barbara, Angela L. H. Buffington, Kathleen A. Welsh-Bohmer, Jason Brandt, and Jason ADAPT Research Group. “Time of day affects episodic memory in older adults.” Neuropsychol Dev Cogn B Aging Neuropsychol Cogn 15, no. 2 (March 2008): 146–64. https://doi.org/10.1080/13825580601186643.
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    • Fillenbaum, Gerda G., Gerald van Belle, John C. Morris, Richard C. Mohs, Suzanne S. Mirra, Patricia C. Davis, Pierre N. Tariot, et al. “Consortium to Establish a Registry for Alzheimer's Disease (CERAD): the first twenty years.” Alzheimers Dement 4, no. 2 (March 2008): 96–109. https://doi.org/10.1016/j.jalz.2007.08.005.
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    • Welsh-Bohmer, Kathleen A. “Defining "prodromal" Alzheimer's disease, frontotemporal dementia, and Lewy body dementia: are we there yet?” Neuropsychol Rev 18, no. 1 (March 2008): 70–72. https://doi.org/10.1007/s11065-008-9057-y.
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    • Steinberg, Martin, Huibo Shao, Peter Zandi, Constantine G. Lyketsos, Kathleen A. Welsh-Bohmer, Maria C. Norton, John C. S. Breitner, David C. Steffens, Joann T. Tschanz, and Joann T. Cache County Investigators. “Point and 5-year period prevalence of neuropsychiatric symptoms in dementia: the Cache County Study.” Int J Geriatr Psychiatry 23, no. 2 (February 2008): 170–77. https://doi.org/10.1002/gps.1858.
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    • Heinzen, E. L., D. Ge, K. D. Cronin, J. M. Maia, K. V. Shianna, W. N. Gabriel, K. A. Welsh-Bohmer, C. M. Hulette, T. N. Denny, and D. B. Goldstein. “Tissue-specific genetic control of splicing: Implications for the study of complex traits.” Plos Biology 6, no. 12 (2008): 2869–79. https://doi.org/10.1371/journal.pbio.1000001.
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    • Ervin, John F., Erin L. Heinzen, Kenneth D. Cronin, David Goldstein, Mari H. Szymanski, James R. Burke, Kathleen A. Welsh-Bohmer, and Christine M. Hulette. “Postmortem delay has minimal effect on brain RNA integrity.” J Neuropathol Exp Neurol 66, no. 12 (December 2007): 1093–99. https://doi.org/10.1097/nen.0b013e31815c196a.
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    • Potter, Guy G., Andrew D. Blackwell, Douglas R. McQuoid, Martha E. Payne, David C. Steffens, Barbara J. Sahakian, Kathleen A. Welsh-Bohmer, and KR Ranga Krishnan. “Prefrontal white matter lesions and prefrontal task impersistence in depressed and nondepressed elders.” Neuropsychopharmacology 32, no. 10 (October 2007): 2135–42. https://doi.org/10.1038/sj.npp.1301339.
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    • Steffens, David C., Guy G. Potter, Douglas R. McQuoid, James R. MacFall, Martha E. Payne, James R. Burke, Brenda L. Plassman, and Kathleen A. Welsh-Bohmer. “Longitudinal magnetic resonance imaging vascular changes, apolipoprotein E genotype, and development of dementia in the neurocognitive outcomes of depression in the elderly study.” Am J Geriatr Psychiatry 15, no. 10 (October 2007): 839–49. https://doi.org/10.1097/JGP.0b013e318048a1a0.
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    • Hayden, K. M., P. P. Zandi, A. S. Khachaturian, C. A. Szekely, M. Fotuhi, M. C. Norton, J. T. Tschanz, et al. “Does NSAID use modify cognitive trajectories in the elderly? The Cache County study.” Neurology 69, no. 3 (July 17, 2007): 275–82. https://doi.org/10.1212/01.wnl.0000265223.25679.2a.
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    • Fearing, Michael A., Erin D. Bigler, Maria Norton, Jo Ann Tschanz, Christine Hulette, Carol Leslie, Kathleen Welsh-Bohmer, and Kathleen Cache County Investigators. “Autopsy-confirmed Alzheimer's disease versus clinically diagnosed Alzheimer's disease in the Cache County Study on Memory and Aging: a comparison of quantitative MRI and neuropsychological findings.” J Clin Exp Neuropsychol 29, no. 5 (July 2007): 553–60. https://doi.org/10.1080/13803390600826579.
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    • Onyike, Chiadi U., Jeannie-Marie E. Sheppard, JoAnn T. Tschanz, Maria C. Norton, Robert C. Green, Martin Steinberg, Kathleen A. Welsh-Bohmer, John C. Breitner, and Constantine G. Lyketsos. “Epidemiology of apathy in older adults: the Cache County Study.” Am J Geriatr Psychiatry 15, no. 5 (May 2007): 365–75. https://doi.org/10.1097/01.JGP.0000235689.42910.0d.
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    • Sugarman, Jeremy, Debra Roter, Carole Cain, Roberta Wallace, Don Schmechel, and Kathleen A. Welsh-Bohmer. “Proxies and consent discussions for dementia research.” J Am Geriatr Soc 55, no. 4 (April 2007): 556–61. https://doi.org/10.1111/j.1532-5415.2007.01101.x.
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    • Hulette, Christine M., and Kathleen Welsh-Bohmer. “Coronary artery disease is associated with Alzheimer disease neuropathology in APOE4 carriers.” Neurology 68, no. 6 (February 6, 2007): 471. https://doi.org/10.1212/01.wnl.0000256286.78188.dd.
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    • Hayden, Kathleen M., Kathleen A. Welsh-Bohmer, Heidi J. Wengreen, Peter P. Zandi, Constantine G. Lyketsos, John C. S. Breitner, and John C. S. Cache County Investigators. “Risk of mortality with vitamin E supplements: the Cache County study.” Am J Med 120, no. 2 (February 2007): 180–84. https://doi.org/10.1016/j.amjmed.2006.03.039.
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    • Lee, Jung Sik, Guy G. Potter, H Ryan Wagner, Kathleen A. Welsh-Bohmer, and David C. Steffens. “Persistent mild cognitive impairment in geriatric depression.” Int Psychogeriatr 19, no. 1 (February 2007): 125–35. https://doi.org/10.1017/S1041610206003607.
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    • Heinzen, Erin L., Woohyun Yoon, Michael E. Weale, Arjune Sen, Nicholas W. Wood, James R. Burke, Kathleen A. Welsh-Bohmer, Christine M. Hulette, Sanjay M. Sisodiya, and David B. Goldstein. “Alternative ion channel splicing in mesial temporal lobe epilepsy and Alzheimer's disease.” Genome Biol 8, no. 3 (2007): R32. https://doi.org/10.1186/gb-2007-8-3-r32.
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    • Trembath, Dimitri, John F. Ervin, Lucy Broom, Mari Szymanski, Kathleen Welsh-Bohmer, Carl Pieper, and Christine M. Hulette. “The distribution of cerebrovascular amyloid in Alzheimer's disease varies with ApoE genotype.” Acta Neuropathol 113, no. 1 (January 2007): 23–31. https://doi.org/10.1007/s00401-006-0162-9.
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    • Plassman, Brenda L., David C. Steffens, James R. Burke, Kathleen A. Welsh-Bohmer, Tiffany N. Newman, Deborah Drosdick, Michael J. Helms, Guy G. Potter, and John C. S. Breitner. “Duke Twins Study of Memory in Aging in the NAS-NRC Twin Registry.” Twin Res Hum Genet 9, no. 6 (December 2006): 950–57. https://doi.org/10.1375/183242706779462381.
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    • Steinberg, M., C. Corcoran, J. T. Tschanz, C. Huber, K. Welsh-Bohmer, M. C. Norton, P. Zandi, J. C. S. Breitner, D. C. Steffens, and C. G. Lyketsos. “Risk factors for neuropsychiatric symptoms in dementia: the Cache County Study.” Int J Geriatr Psychiatry 21, no. 9 (September 2006): 824–30. https://doi.org/10.1002/gps.1567.
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    • Newman, Mark F., Joseph P. Mathew, Hilary P. Grocott, G Burkhard Mackensen, Terri Monk, Kathleen A. Welsh-Bohmer, James A. Blumenthal, Daniel T. Laskowitz, and Daniel B. Mark. “Central nervous system injury associated with cardiac surgery.” Lancet 368, no. 9536 (August 19, 2006): 694–703. https://doi.org/10.1016/S0140-6736(06)69254-4.
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    • Tschanz, J. T., K. A. Welsh-Bohmer, C. G. Lyketsos, C. Corcoran, R. C. Green, K. Hayden, M. C. Norton, et al. “Conversion to dementia from mild cognitive disorder: the Cache County Study.” Neurology 67, no. 2 (July 25, 2006): 229–34. https://doi.org/10.1212/01.wnl.0000224748.48011.84.
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    • Lin, P. I., E. R. Martin, P. G. Bronson, C. Browning-Large, G. W. Small, D. E. Schmechel, K. A. Welsh-Bohmer, J. L. Haines, J. R. Gilbert, and M. A. Pericak-Vance. “Exploring the association of glyceraldehyde-3-phosphate dehydrogenase gene and Alzheimer disease.” Neurology 67, no. 1 (July 11, 2006): 64–68. https://doi.org/10.1212/01.wnl.0000223438.90113.4e.
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    • Akomolafe, A., K. L. Lunetta, P. M. Erlich, L. A. Cupples, C. T. Baldwin, M. Huyck, R. C. Green, L. A. Farrer, and L. A. MIRAGE Study Group. “Genetic association between endothelial nitric oxide synthase and Alzheimer disease.” Clin Genet 70, no. 1 (July 2006): 49–56. https://doi.org/10.1111/j.1399-0004.2006.00638.x.
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    • Lin, Ping-I, Eden R. Martin, Carrie A. Browning-Large, Donald E. Schmechel, Kathleen A. Welsh-Bohmer, P Murali Doraiswamy, John R. Gilbert, Jonathan L. Haines, and Margaret A. Pericak-Vance. “Parsing the genetic heterogeneity of chromosome 12q susceptibility genes for Alzheimer disease by family-based association analysis.” Neurogenetics 7, no. 3 (July 2006): 157–65. https://doi.org/10.1007/s10048-006-0047-z.
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    • Sheline, Yvette I., Deanna M. Barch, Keith Garcia, Kenneth Gersing, Carl Pieper, Kathleen Welsh-Bohmer, David C. Steffens, and P Murali Doraiswamy. “Cognitive function in late life depression: relationships to depression severity, cerebrovascular risk factors and processing speed.” Biol Psychiatry 60, no. 1 (July 1, 2006): 58–65. https://doi.org/10.1016/j.biopsych.2005.09.019.
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    • Welsh-Bohmer, Kathleen A., John C. S. Breitner, Kathleen M. Hayden, Constantine Lyketsos, Peter P. Zandi, Joann T. Tschanz, Maria C. Norton, and Ron Munger. “Modifying dementia risk and trajectories of cognitive decline in aging: the Cache County Memory Study.” Alzheimers Dement 2, no. 3 (July 2006): 257–60. https://doi.org/10.1016/j.jalz.2006.04.011.
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    • Lyketsos, Constantine G., Leslie Toone, Joann Tschanz, Christopher Corcoran, Maria Norton, Peter Zandi, Ron Munger, John C. S. Breitner, Kathleen Welsh-Bohmer, and Kathleen Cache County Study Group. “A population-based study of the association between coronary artery bypass graft surgery (CABG) and cognitive decline: the Cache County study.” Int J Geriatr Psychiatry 21, no. 6 (June 2006): 509–18. https://doi.org/10.1002/gps.1502.
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    • Norton, Maria C., Ingmar Skoog, Lynn M. Franklin, Christopher Corcoran, JoAnn T. Tschanz, Peter P. Zandi, John C. S. Breitner, Kathleen A. Welsh-Bohmer, David C. Steffens, and David C. Cache County Investigators. “Gender differences in the association between religious involvement and depression: the Cache County (Utah) study.” J Gerontol B Psychol Sci Soc Sci 61, no. 3 (May 2006): P129–36. https://doi.org/10.1093/geronb/61.3.p129.
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    • Khachaturian, Ara S., Peter P. Zandi, Constantine G. Lyketsos, Kathleen M. Hayden, Ingmar Skoog, Maria C. Norton, JoAnn T. Tschanz, Lawrence S. Mayer, Kathleen A. Welsh-Bohmer, and John C. S. Breitner. “Antihypertensive medication use and incident Alzheimer disease: the Cache County Study.” Arch Neurol 63, no. 5 (May 2006): 686–92. https://doi.org/10.1001/archneur.63.5.noc60013.
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    • Slifer, M. A., E. R. Martin, P. G. Bronson, C. Browning-Large, P. M. Doraiswamy, K. A. Welsh-Bohmer, J. R. Gilbert, J. L. Haines, and M. A. Pericak-Vance. “Lack of association between UBQLN1 and Alzheimer disease.” Am J Med Genet B Neuropsychiatr Genet 141B, no. 3 (April 5, 2006): 208–13. https://doi.org/10.1002/ajmg.b.30298.
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    • McCauley, Jacob L., Daniel W. Hahs, Lan Jiang, William K. Scott, Kathleen A. Welsh-Bohmer, Charles E. Jackson, Jeffery M. Vance, Margaret A. Pericak-Vance, and Jonathan L. Haines. “Combinatorial Mismatch Scan (CMS) for loci associated with dementia in the Amish.” Bmc Med Genet 7 (March 3, 2006): 19. https://doi.org/10.1186/1471-2350-7-19.
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    • Norton, Maria C., Ingmar Skoog, Leslie Toone, Christopher Corcoran, Joann T. Tschanz, Robert D. Lisota, Andrea D. Hart, et al. “Three-year incidence of first-onset depressive syndrome in a population sample of older adults: the Cache County study.” Am J Geriatr Psychiatry 14, no. 3 (March 2006): 237–45. https://doi.org/10.1097/01.JGP.0000196626.34881.42.
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    • Steffens, David C., Emeline Otey, George S. Alexopoulos, Meryl A. Butters, Bruce Cuthbert, Mary Ganguli, Yonas E. Geda, et al. “Perspectives on depression, mild cognitive impairment, and cognitive decline.” Arch Gen Psychiatry 63, no. 2 (February 2006): 130–38. https://doi.org/10.1001/archpsyc.63.2.130.
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    • Østbye, Truls, Katrina M. Krause, Maria C. Norton, JoAnn Tschanz, Linda Sanders, Kathleen Hayden, Carl Pieper, Kathleen A. Welsh-Bohmer, and Kathleen A. Cache County Investigators. “Ten dimensions of health and their relationships with overall self-reported health and survival in a predominately religiously active elderly population: the cache county memory study.” J Am Geriatr Soc 54, no. 2 (February 2006): 199–209. https://doi.org/10.1111/j.1532-5415.2005.00583.x.
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    • Sair, Haris I., Kathleen A. Welsh-Bohmer, H Ryan Wagner, and David C. Steffens. “Ascending digits task as a measure of executive function in geriatric depression.” J Neuropsychiatry Clin Neurosci 18, no. 1 (2006): 117–20. https://doi.org/10.1176/jnp.18.1.117.
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    • Erlich, Porat M., Kathryn L. Lunetta, L Adrienne Cupples, Matthew Huyck, Robert C. Green, Clinton T. Baldwin, Lindsay A. Farrer, and Lindsay A. MIRAGE Study Group. “Polymorphisms in the PON gene cluster are associated with Alzheimer disease.” Hum Mol Genet 15, no. 1 (January 1, 2006): 77–85. https://doi.org/10.1093/hmg/ddi428.
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    • Hayden, Kathleen M., Peter P. Zandi, Constantine G. Lyketsos, Ara S. Khachaturian, Lori A. Bastian, Gene Charoonruk, JoAnn T. Tschanz, et al. “Vascular risk factors for incident Alzheimer disease and vascular dementia: the Cache County study.” Alzheimer Dis Assoc Disord 20, no. 2 (2006): 93–100. https://doi.org/10.1097/01.wad.0000213814.43047.86.
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    • Plassman, Brenda L., Ara S. Khachaturian, Jeannette J. Townsend, Melvyn J. Ball, David C. Steffens, Carol E. Leslie, JoAnn T. Tschanz, et al. “Comparison of clinical and neuropathologic diagnoses of Alzheimer's disease in 3 epidemiologic samples.” Alzheimers Dement 2, no. 1 (January 2006): 2–11. https://doi.org/10.1016/j.jalz.2005.11.001.
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    • Walt, Joelle M. van der, William K. Scott, Susan Slifer, P. C. Gaskell, Eden R. Martin, Kathleen Welsh-Bohmer, Marilyn Creason, et al. “Maternal lineages and Alzheimer disease risk in the Old Order Amish.” Hum Genet 118, no. 1 (October 2005): 115–22. https://doi.org/10.1007/s00439-005-0032-x.
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    • Lyketsos, Constantine G., Leslie Toone, JoAnn Tschanz, Peter V. Rabins, Martin Steinberg, Chiadi U. Onyike, Christopher Corcoran, et al. “Population-based study of medical comorbidity in early dementia and "cognitive impairment, no dementia (CIND)": association with functional and cognitive impairment: The Cache County Study.” Am J Geriatr Psychiatry 13, no. 8 (August 2005): 656–64. https://doi.org/10.1176/appi.ajgp.13.8.656.
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    • Hayden, K. M., L. H. Warren, C. F. Pieper, T. Østbye, J. T. Tschanz, M. C. Norton, J. C. S. Breitner, and K. A. Welsh-Bohmer. “Identification of VaD and AD prodromes: the Cache County Study.” Alzheimers Dement 1, no. 1 (July 2005): 19–29. https://doi.org/10.1016/j.jalz.2005.06.002.
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    • Hayden, Kathleen M., Peter P. Zandi, Constantine G. Lyketsos, JoAnn T. Tschanz, Maria C. Norton, Ara S. Khachaturian, Carl F. Pieper, Kathleen A. Welsh-Bohmer, John C. S. Breitner, and John C. S. Cache County Investigators. “Apolipoprotein E genotype and mortality: findings from the Cache County Study.” J Am Geriatr Soc 53, no. 6 (June 2005): 935–42. https://doi.org/10.1111/j.1532-5415.2005.53301.x.
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    • Ashley-Koch, A. E., Y. Shao, J. B. Rimmler, P. C. Gaskell, K. A. Welsh-Bohmer, C. E. Jackson, W. K. Scott, J. L. Haines, and M. A. Pericak-Vance. “An autosomal genomic screen for dementia in an extended Amish family.” Neurosci Lett 379, no. 3 (May 13, 2005): 199–204. https://doi.org/10.1016/j.neulet.2004.12.065.
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    • Zandi, Peter P., D Larry Sparks, Ara S. Khachaturian, Joann Tschanz, Maria Norton, Martin Steinberg, Kathleen A. Welsh-Bohmer, John C. S. Breitner, and John C. S. Cache County Study investigators. “Do statins reduce risk of incident dementia and Alzheimer disease? The Cache County Study.” Arch Gen Psychiatry 62, no. 2 (February 2005): 217–24. https://doi.org/10.1001/archpsyc.62.2.217.
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    • LaBar, Kevin S., Dana C. Torpey, Craig A. Cook, Stephanie R. Johnson, Lauren H. Warren, James R. Burke, and Kathleen A. Welsh-Bohmer. “Emotional enhancement of perceptual priming is preserved in aging and early-stage Alzheimer's disease.” Neuropsychologia 43, no. 12 (2005): 1824–37. https://doi.org/10.1016/j.neuropsychologia.2005.01.018.
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    • Tschanz, Joann T., Katherine Treiber, Maria C. Norton, Kathleen A. Welsh-Bohmer, Leslie Toone, Peter P. Zandi, Christine A. Szekely, Constantine Lyketsos, John C. S. Breitner, and John C. S. Cache County Study Group. “A population study of Alzheimer's disease: findings from the Cache County Study on Memory, Health, and Aging.” Care Manag J 6, no. 2 (2005): 107–14. https://doi.org/10.1891/cmaj.6.2.107.
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    • Potter, G. G., B. L. Plassman, M. J. Helms, D. C. Steffens, and K. A. Welsh-Bohmer. “Age effects of coronary artery bypass graft on cognitive status change among elderly male twins.” Neurology 63, no. 12 (December 28, 2004): 2245–49. https://doi.org/10.1212/01.wnl.0000147291.49404.0a.
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    • Nicodemus, Kristin K., Judith E. Stenger, Donald E. Schmechel, Kathleen A. Welsh-Bohmer, Ann M. Saunders, Allen D. Roses, John R. Gilbert, et al. “Comprehensive association analysis of APOE regulatory region polymorphisms in Alzheimer disease.” Neurogenetics 5, no. 4 (December 2004): 201–8. https://doi.org/10.1007/s10048-004-0189-9.
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    • Steffens, David C., Kathleen A. Welsh-Bohmer, James R. Burke, Brenda L. Plassman, John L. Beyer, Kenneth R. Gersing, and Guy G. Potter. “Methodology and preliminary results from the neurocognitive outcomes of depression in the elderly study.” J Geriatr Psychiatry Neurol 17, no. 4 (December 2004): 202–11. https://doi.org/10.1177/0891988704269819.
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    • Labar, Kevin S., Craig A. Cook, Dana C. Torpey, and Kathleen A. Welsh-Bohmer. “Impact of healthy aging on awareness and fear conditioning.” Behav Neurosci 118, no. 5 (October 2004): 905–15. https://doi.org/10.1037/0735-7044.118.5.905.
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    • Walt, Joelle M. van der, Yulia A. Dementieva, Eden R. Martin, William K. Scott, Kristin K. Nicodemus, Charles C. Kroner, Kathleen A. Welsh-Bohmer, et al. “Analysis of European mitochondrial haplogroups with Alzheimer disease risk.” Neurosci Lett 365, no. 1 (July 15, 2004): 28–32. https://doi.org/10.1016/j.neulet.2004.04.051.
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    • Ervin, John F., Catherine Pannell, Mari Szymanski, Kathleen Welsh-Bohmer, Donald E. Schmechel, and Christine M. Hulette. “Vascular smooth muscle actin is reduced in Alzheimer disease brain: a quantitative analysis.” J Neuropathol Exp Neurol 63, no. 7 (July 2004): 735–41. https://doi.org/10.1093/jnen/63.7.735.
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    • Hayden, K. M., C. F. Pieper, K. A. Welsh-Bohmer, J. C. S. Breitner, M. C. Norton, and R. Munger. “Self- or proxy-reported stroke and the risk of Alzheimer disease.” Arch Neurol 61, no. 6 (June 2004): 982. https://doi.org/10.1001/archneur.61.6.982.
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    • Bigler, Erin D., E Shannon Neeley, Michael J. Miller, David F. Tate, Sara A. Rice, Howard Cleavinger, Lara Wolfson, Joann Tschanz, and Kathleen Welsh-Bohmer. “Cerebral volume loss, cognitive deficit and neuropsychological performance: comparative measures of brain atrophy: I. Dementia.” J Int Neuropsychol Soc 10, no. 3 (May 2004): 442–52. https://doi.org/10.1017/S1355617704103111.
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    • Tschanz, J. T., C. Corcoran, I. Skoog, A. S. Khachaturian, J. Herrick, K. M. Hayden, K. A. Welsh-Bohmer, et al. “Dementia: the leading predictor of death in a defined elderly population: the Cache County Study.” Neurology 62, no. 7 (April 13, 2004): 1156–62. https://doi.org/10.1212/01.wnl.0000118210.12660.c2.
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    • Li, Y. L., S. A. Oliveira, P. Xu, E. R. Martin, J. E. Stenger, C. Hulette, C. R. Scherzer, et al. “Erratum: Glutathione S-transferase omega-1 modifies age-at-onset of Alzheimer disease and Parkinson disease (Human Molecular Genetics (2003) vol. 12 (3259-3267)).” Human Molecular Genetics 13, no. 5 (March 1, 2004): 573. https://doi.org/10.1093/hmg/ddh059.
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    • Zandi, Peter P., James C. Anthony, Ara S. Khachaturian, Stephanie V. Stone, Deborah Gustafson, JoAnn T. Tschanz, Maria C. Norton, Kathleen A. Welsh-Bohmer, John C. S. Breitner, and John C. S. Cache County Study Group. “Reduced risk of Alzheimer disease in users of antioxidant vitamin supplements: the Cache County Study.” Arch Neurol 61, no. 1 (January 2004): 82–88. https://doi.org/10.1001/archneur.61.1.82.
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    • Steffens, David C., Douglas R. McQuoid, Kathleen A. Welsh-Bohmer, and K Ranga Rama Krishnan. “Left orbital frontal cortex volume and performance on the benton visual retention test in older depressives and controls.” Neuropsychopharmacology 28, no. 12 (December 2003): 2179–83. https://doi.org/10.1038/sj.npp.1300285.
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    • Scott, William K., Elizabeth R. Hauser, Donald E. Schmechel, Kathleen A. Welsh-Bohmer, Gary W. Small, Allen D. Roses, Ann M. Saunders, et al. “Ordered-subsets linkage analysis detects novel Alzheimer disease loci on chromosomes 2q34 and 15q22.” Am J Hum Genet 73, no. 5 (November 2003): 1041–51. https://doi.org/10.1086/379083.
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    • Bigler, Erin D., Christopher M. Lowry, Burton Kerr, David F. Tate, Cory D. Hessel, Heath D. Earl, Michael J. Miller, et al. “Role of white matter lesions, cerebral atrophy, and APOE on cognition in older persons with and without dementia: the Cache County, Utah, study of memory and aging.” Neuropsychology 17, no. 3 (July 2003): 339–52. https://doi.org/10.1037/0894-4105.17.3.339.
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    • Steffens, D. C., M. C. Norton, A. D. Hart, I. Skoog, C. Corcoran, J. C. S. Breitner, and J. C. S. Cache County Study Group. “Apolipoprotein E genotype and major depression in a community of older adults. The Cache County Study.” Psychol Med 33, no. 3 (April 2003): 541–47. https://doi.org/10.1017/s0033291702007201.
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    • Phillips Bute, Barbara, Joseph Mathew, James A. Blumenthal, Kathleen Welsh-Bohmer, William D. White, Daniel Mark, Kevin Landolfo, and Mark F. Newman. “Female gender is associated with impaired quality of life 1 year after coronary artery bypass surgery.” Psychosom Med 65, no. 6 (2003): 944–51. https://doi.org/10.1097/01.psy.0000097342.24933.a2.
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    • Zandi, Peter P., Michelle C. Carlson, Brenda L. Plassman, Kathleen A. Welsh-Bohmer, Lawrence S. Mayer, David C. Steffens, John C. S. Breitner, and John C. S. Cache County Memory Study Investigators. “Hormone replacement therapy and incidence of Alzheimer disease in older women: the Cache County Study.” Jama 288, no. 17 (November 6, 2002): 2123–29. https://doi.org/10.1001/jama.288.17.2123.
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    • Bigler, Erin D., David F. Tate, Michael J. Miller, Sara A. Rice, Cory D. Hessel, Heath D. Earl, Joann T. Tschanz, Brenda Plassman, and Kathleen A. Welsh-Bohmer. “Dementia, asymmetry of temporal lobe structures, and apolipoprotein E genotype: relationships to cerebral atrophy and neuropsychological impairment.” J Int Neuropsychol Soc 8, no. 7 (November 2002): 925–33. https://doi.org/10.1017/s1355617702870072.
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    • Li, Yi-Ju, William K. Scott, Dale J. Hedges, Fengyu Zhang, P Craig Gaskell, Martha A. Nance, Ray L. Watts, et al. “Age at onset in two common neurodegenerative diseases is genetically controlled.” Am J Hum Genet 70, no. 4 (April 2002): 985–93. https://doi.org/10.1086/339815.
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    • Tschanz, JoAnn T., Kathleen A. Welsh-Bohmer, Brenda L. Plassman, Maria C. Norton, Bonita W. Wyse, John C. S. Breitner, and John C. S. Cache County Study Group. “An adaptation of the modified mini-mental state examination: analysis of demographic influences and normative data: the cache county study.” Neuropsychiatry Neuropsychol Behav Neurol 15, no. 1 (March 2002): 28–38.
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    • Carlson, Michelle C., JoAnn T. Tschanz, Maria C. Norton, Kathleen Welsh-Bohmer, Barbara K. Martin, and John C. S. Breitner. “H2 histamine receptor blockade in the treatment of Alzheimer disease: a randomized, double-blind, placebo-controlled trial of nizatidine.” Alzheimer Dis Assoc Disord 16, no. 1 (2002): 24–30. https://doi.org/10.1097/00002093-200201000-00004.
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    • Schiffman, S. S., B. G. Graham, E. A. Sattely-Miller, J. Zervakis, and K. Welsh-Bohmer. “Taste, smell and neuropsychological performance of individuals at familial risk for Alzheimer's disease.” Neurobiol Aging 23, no. 3 (2002): 397–404. https://doi.org/10.1016/s0197-4580(01)00337-2.
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    • Steffens, David C., Martha E. Payne, Daniel L. Greenberg, Christopher E. Byrum, Kathleen A. Welsh-Bohmer, H Ryan Wagner, and James R. MacFall. “Hippocampal volume and incident dementia in geriatric depression.” Am J Geriatr Psychiatry 10, no. 1 (2002): 62–71.
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    • Carlson, M. C., P. P. Zandi, B. L. Plassman, J. T. Tschanz, K. A. Welsh-Bohmer, D. C. Steffens, L. A. Bastian, K. M. Mehta, J. C. Breitner, and J. C. Cache County Study Group. “Hormone replacement therapy and reduced cognitive decline in older women: the Cache County Study.” Neurology 57, no. 12 (December 26, 2001): 2210–16. https://doi.org/10.1212/wnl.57.12.2210.
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    • Silverman, D. H., G. W. Small, C. Y. Chang, C. S. Lu, M. A. Kung De Aburto, W. Chen, J. Czernin, et al. “Positron emission tomography in evaluation of dementia: Regional brain metabolism and long-term outcome.” Jama 286, no. 17 (November 7, 2001): 2120–27. https://doi.org/10.1001/jama.286.17.2120.
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    • Sugarman, J., C. Cain, R. Wallace, and K. A. Welsh-Bohmer. “How proxies make decisions about research for patients with Alzheimer's disease.” J Am Geriatr Soc 49, no. 8 (August 2001): 1110–19. https://doi.org/10.1046/j.1532-5415.2001.49218.x.
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    • Koltai, D. C., K. A. Welsh-Bohmer, and D. E. Schmechel. “Influence of anosognosia on treatment outcome among dementia patients.” Neuropsychological Rehabilitation 11, no. 3–4 (July 30, 2001): 455–75. https://doi.org/10.1080/09602010042000097.
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    • Steffens, D. C., J. R. MacFall, M. E. Payne, K. A. Welsh-Bohmer, and K. R. Krishnan. “Grey-matter lesions and dementia.” Lancet 356, no. 9242 (November 11, 2000): 1686–87. https://doi.org/10.1016/S0140-6736(05)70393-7.
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    • Hoffman, J. M., K. A. Welsh-Bohmer, M. Hanson, B. Crain, C. Hulette, N. Earl, and R. E. Coleman. “FDG PET imaging in patients with pathologically verified dementia.” J Nucl Med 41, no. 11 (November 2000): 1920–28.
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    • Plassman, B. L., R. J. Havlik, D. C. Steffens, M. J. Helms, T. N. Newman, D. Drosdick, C. Phillips, et al. “Documented head injury in early adulthood and risk of Alzheimer's disease and other dementias.” Neurology 55, no. 8 (October 24, 2000): 1158–66. https://doi.org/10.1212/wnl.55.8.1158.
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    • Steffens, D. C., I. Skoog, M. C. Norton, A. D. Hart, J. T. Tschanz, B. L. Plassman, B. W. Wyse, K. A. Welsh-Bohmer, and J. C. Breitner. “Prevalence of depression and its treatment in an elderly population: the Cache County study.” Arch Gen Psychiatry 57, no. 6 (June 2000): 601–7. https://doi.org/10.1001/archpsyc.57.6.601.
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    • Tschanz, J. T., K. A. Welsh-Bohmer, I. Skoog, N. West, M. C. Norton, B. W. Wyse, R. Nickles, and J. C. Breitner. “Dementia diagnoses from clinical and neuropsychological data compared: the Cache County study.” Neurology 54, no. 6 (March 28, 2000): 1290–96. https://doi.org/10.1212/wnl.54.6.1290.
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    • Steffens, D. C., B. L. Plassman, M. J. Helms, K. A. Welsh-Bohmer, T. T. Newman, and J. C. Breitner. “APOE and AD concordance in twin pairs as predictors of AD in first-degree relatives.” Neurology 54, no. 3 (February 8, 2000): 593–98. https://doi.org/10.1212/wnl.54.3.593.
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    • Clark, L. M., H. B. Bosworth, K. A. Welsh-Bohmer, D. V. Dawson, and I. C. Siegler. “Relation between informant-rated personality and clinician-rated depression in patients with memory disorders.” Neuropsychiatry Neuropsychol Behav Neurol 13, no. 1 (January 2000): 39–47.
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    • Dawson, D. V., K. A. Welsh-Bohmer, and I. C. Siegler. “Premorbid personality predicts level of rated personality change in patients with Alzheimer disease.” Alzheimer Dis Assoc Disord 14, no. 1 (2000): 11–19. https://doi.org/10.1097/00002093-200001000-00002.
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    • Welsh-Bohmer, K. A., and J. C. Morgenlander. “Determining the cause of memory loss in the elderly. From in-office screening to neuropsychological referral.” Postgrad Med 106, no. 5 (October 15, 1999): 99-passim. https://doi.org/10.3810/pgm.1999.10.15.747.
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    • Norton, M. C., J. A. Tschanz, X. Fan, B. L. Plassman, K. A. Welsh-Bohmer, N. West, B. W. Wyse, and J. C. Breitner. “Telephone adaptation of the Modified Mini-Mental State Exam (3MS). The Cache County Study.” Neuropsychiatry Neuropsychol Behav Neurol 12, no. 4 (October 1999): 270–76.
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    • Steffens, D. C., M. C. Norton, B. L. Plassman, J. T. Tschanz, B. W. Wyse, K. A. Welsh-Bohmer, J. C. Anthony, and J. C. Breitner. “Enhanced cognitive performance with estrogen use in nondemented community-dwelling older women.” J Am Geriatr Soc 47, no. 10 (October 1999): 1171–75. https://doi.org/10.1111/j.1532-5415.1999.tb05195.x.
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    • Hulette, C. M., M. A. Pericak-Vance, A. D. Roses, D. E. Schmechel, L. H. Yamaoka, P. C. Gaskell, K. A. Welsh-Bohmer, R. A. Crowther, and M. G. Spillantini. “Neuropathological features of frontotemporal dementia and parkinsonism linked to chromosome 17q21-22 (FTDP-17): Duke Family 1684.” J Neuropathol Exp Neurol 58, no. 8 (August 1999): 859–66. https://doi.org/10.1097/00005072-199908000-00008.
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    • Breitner, J. C., B. W. Wyse, J. C. Anthony, K. A. Welsh-Bohmer, D. C. Steffens, M. C. Norton, J. T. Tschanz, et al. “APOE-epsilon4 count predicts age when prevalence of AD increases, then declines: the Cache County Study.” Neurology 53, no. 2 (July 22, 1999): 321–31. https://doi.org/10.1212/wnl.53.2.321.
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    • Heyman, A., G. G. Fillenbaum, M. Gearing, S. S. Mirra, K. A. Welsh-Bohmer, B. Peterson, and C. Pieper. “Comparison of Lewy body variant of Alzheimer's disease with pure Alzheimer's disease: Consortium to Establish a Registry for Alzheimer's Disease, Part XIX.” Neurology 52, no. 9 (June 10, 1999): 1839–44. https://doi.org/10.1212/wnl.52.9.1839.
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    • Watson, M. E., K. A. Welsh-Bohmer, J. M. Hoffman, V. Lowe, and D. C. Rubin. “The neural basis of naming impairments in Alzheimer's disease revealed through positron emission tomography.” Arch Clin Neuropsychol 14, no. 4 (May 1999): 347–57.
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    • McKinney, C. J., E. R. MacCormac, and K. A. Welsh-Bohmer. “Hardware and software for tachistoscopy: how to make accurate measurements on any PC utilizing the Microsoft Windows operating system.” Behav Res Methods Instrum Comput 31, no. 1 (February 1999): 129–36. https://doi.org/10.3758/bf03207703.
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    • Madden, D. J., K. A. Welsh-Bohmer, and L. A. Tupler. “Task complexity and signal detection analyses of lexical decision performance in Alzheimer's disease.” Developmental Neuropsychology 16, no. 1 (January 1, 1999): 1–18. https://doi.org/10.1207/S15326942DN160101.
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    • Hulette, C. M., K. A. Welsh-Bohmer, M. G. Murray, A. M. Saunders, D. C. Mash, and L. M. McIntyre. “Neuropathological and neuropsychological changes in "normal" aging: evidence for preclinical Alzheimer disease in cognitively normal individuals.” J Neuropathol Exp Neurol 57, no. 12 (December 1998): 1168–74. https://doi.org/10.1097/00005072-199812000-00009.
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    • Clark, L. M., W. M. McDonald, K. A. Welsh-Bohmer, I. C. Siegler, D. V. Dawson, L. A. Tupler, and K. R. Krishnan. “Magnetic resonance imaging correlates of depression in early- and late-onset Alzheimer's disease.” Biol Psychiatry 44, no. 7 (October 1, 1998): 592–99. https://doi.org/10.1016/s0006-3223(98)00106-1.
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    • Meyer, M. R., J. T. Tschanz, M. C. Norton, K. A. Welsh-Bohmer, D. C. Steffens, B. W. Wyse, and J. C. Breitner. “APOE genotype predicts when--not whether--one is predisposed to develop Alzheimer disease.” Nat Genet 19, no. 4 (August 1998): 321–22. https://doi.org/10.1038/1206.
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    • Bass, M. P., L. H. Yamaoka, W. K. Scott, P. C. Gaskell, K. A. Welsh-Bohmer, A. D. Roses, A. M. Saunders, J. L. Haines, and M. A. Pericak-Vance. “No association of alpha1-antichymotrypsin flanking region polymorphism and Alzheimer disease risk in early- and late-onset Alzheimer disease patients.” Neurosci Lett 250, no. 2 (July 3, 1998): 79–82. https://doi.org/10.1016/s0304-3940(98)00398-x.
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    • Fillenbaum, G. G., B. Peterson, K. A. Welsh-Bohmer, W. A. Kukull, and A. Heyman. “Progression of Alzheimer's disease in black and white patients: the CERAD experience, part XVI. Consortium to Establish a Registry for Alzheimer's Disease.” Neurology 51, no. 1 (July 1998): 154–58. https://doi.org/10.1212/wnl.51.1.154.
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    • Heyman, A., G. G. Fillenbaum, K. A. Welsh-Bohmer, M. Gearing, S. S. Mirra, R. C. Mohs, B. L. Peterson, and C. F. Pieper. “Cerebral infarcts in patients with autopsy-proven Alzheimer's disease: CERAD, part XVIII. Consortium to Establish a Registry for Alzheimer's Disease.” Neurology 51, no. 1 (July 1998): 159–62. https://doi.org/10.1212/wnl.51.1.159.
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    • Ikeuchi, T., K. Sanpei, H. Takano, H. Sasaki, K. Tashiro, G. Cancel, A. Brice, et al. “A novel long and unstable CAG/CTG trinucleotide repeat on chromosome 17q.” Genomics 49, no. 2 (April 15, 1998): 321–26. https://doi.org/10.1006/geno.1998.5266.
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    • Breitner, J. C., G. P. Jarvik, B. L. Plassman, A. M. Saunders, and K. A. Welsh. “Risk of Alzheimer disease with the epsilon4 allele for apolipoprotein E in a population-based study of men aged 62-73 years.” Alzheimer Dis Assoc Disord 12, no. 1 (March 1998): 40–44. https://doi.org/10.1097/00002093-199803000-00006.
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    • Welsh-Bohmer, K. A., M. Gearing, A. M. Saunders, A. D. Roses, and S. Mirra. “Apolipoprotein E genotypes in a neuropathological series from the Consortium to Establish a Registry for Alzheimer's Disease.” Ann Neurol 42, no. 3 (September 1997): 319–25. https://doi.org/10.1002/ana.410420308.
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    • Welsh-Bohmer, K. A., and R. C. Mohs. “Neuropsychological assessment of Alzheimer's disease.” Neurology 49, no. 3 Suppl 3 (September 1997): S11–13. https://doi.org/10.1212/wnl.49.3_suppl_3.s11.
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    • Hulette, C. M., K. A. Welsh-Bohmer, B. Crain, M. H. Szymanski, N. O. Sinclaire, and A. D. Roses. “Rapid brain autopsy. The Joseph and Kathleen Bryan Alzheimer's Disease Research Center experience.” Arch Pathol Lab Med 121, no. 6 (June 1997): 615–18.
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    • Steffens, D. C., B. L. Plassman, M. J. Helms, K. A. Welsh-Bohmer, A. M. Saunders, and J. C. Breitner. “A twin study of late-onset depression and apolipoprotein E epsilon 4 as risk factors for Alzheimer's disease.” Biol Psychiatry 41, no. 8 (April 15, 1997): 851–56. https://doi.org/10.1016/S0006-3223(96)00247-8.
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    • Plassman, B. L., K. A. Welsh-Bohmer, E. D. Bigler, S. C. Johnson, C. V. Anderson, M. J. Helms, A. M. Saunders, and J. C. Breitner. “Apolipoprotein E epsilon 4 allele and hippocampal volume in twins with normal cognition.” Neurology 48, no. 4 (April 1997): 985–89. https://doi.org/10.1212/wnl.48.4.985.
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    • Yamaoka, L. H., K. A. Welsh-Bohmer, C. M. Hulette, P. C. Gaskell, M. Murray, J. L. Rimmler, B. R. Helms, et al. “Linkage of frontotemporal dementia to chromosome 17: clinical and neuropathological characterization of phenotype.” Am J Hum Genet 59, no. 6 (December 1996): 1306–12.
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    • Davidson, M., P. Harvey, K. A. Welsh, P. Powchik, K. M. Putnam, and R. C. Mohs. “Cognitive functioning in late-life schizophrenia: a comparison of elderly schizophrenic patients and patients with Alzheimer's disease.” Am J Psychiatry 153, no. 10 (October 1996): 1274–79. https://doi.org/10.1176/ajp.153.10.1274.
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    • Saunders, A. M., O. Hulette, K. A. Welsh-Bohmer, D. E. Schmechel, B. Crain, J. R. Burke, M. J. Alberts, W. J. Strittmatter, J. C. Breitner, and C. Rosenberg. “Specificity, sensitivity, and predictive value of apolipoprotein-E genotyping for sporadic Alzheimer's disease.” Lancet 348, no. 9020 (July 13, 1996): 90–93. https://doi.org/10.1016/s0140-6736(96)01251-2.
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    • Hoffman, J. M., M. W. Hanson, K. A. Welsh, N. Earl, S. Paine, D. Delong, and R. E. Coleman. “Interpretation variability of 18FDG-positron emission tomography studies in dementia.” Invest Radiol 31, no. 6 (June 1996): 316–22. https://doi.org/10.1097/00004424-199606000-00002.
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    • Steffens, D. C., K. A. Welsh, J. R. Burke, M. J. Helms, M. F. Folstein, J. Brandt, W. M. McDonald, and J. C. S. Breitner. “Diagnosis of Alzheimer's disease in epidemiologic studies by staged review of clinical data.” Neuropsychiatry, Neuropsychology and Behavioral Neurology 9, no. 2 (April 1, 1996): 107–13.
    • Welsh, K. A., G. Fillenbaum, W. Wilkinson, A. Heyman, R. C. Mohs, Y. Stern, L. Harrell, S. D. Edland, and D. Beekly. “Neuropsychological test performance in African-American and white patients with Alzheimer's disease.” Neurology 45, no. 12 (December 1995): 2207–11. https://doi.org/10.1212/wnl.45.12.2207.
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    • Deguchi, A., K. Ohnishi, H. Nakagawa, H. Hamaguchi, H. Shiku, and K. Deguchi. “Lipoprotein(A) and effective renal plasma flow rate in older patients with arteriosclerotic diseases.” J Am Geriatr Soc 43, no. 9 (September 1995): 1067–68. https://doi.org/10.1111/j.1532-5415.1995.tb05582.x.
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    • Breitner, J. C., K. A. Welsh, B. A. Gau, W. M. McDonald, D. C. Steffens, A. M. Saunders, K. M. Magruder, M. J. Helms, B. L. Plassman, and M. F. Folstein. “Alzheimer's disease in the National Academy of Sciences-National Research Council Registry of Aging Twin Veterans. III. Detection of cases, longitudinal results, and observations on twin concordance.” Arch Neurol 52, no. 8 (August 1995): 763–71. https://doi.org/10.1001/archneur.1995.00540320035011.
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    • Plassman, B. L., K. A. Welsh, M. Helms, J. Brandt, W. F. Page, and J. C. Breitner. “Intelligence and education as predictors of cognitive state in late life: a 50-year follow-up.” Neurology 45, no. 8 (August 1995): 1446–50. https://doi.org/10.1212/wnl.45.8.1446.
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    • Tupler, L. A., K. A. Welsh, Y. Asare-Aboagye, and D. V. Dawson. “Reliability of the Rey-Osterrieth Complex Figure in use with memory-impaired patients.” J Clin Exp Neuropsychol 17, no. 4 (August 1995): 566–79. https://doi.org/10.1080/01688639508405146.
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    • Smith, C. J., P. M. Lippiello, and J. W. Ashford. “Smoking, Alzheimer's disease, and confounding with genes.” Lancet 345, no. 8956 (April 22, 1995): 1054. https://doi.org/10.1016/s0140-6736(95)90796-3.
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    • Plassman, B. L., M. J. Helms, K. A. Welsh, A. M. Saunders, and J. C. Breitner. “Smoking, Alzheimer's disease, and confounding with genes.” Lancet 345, no. 8946 (February 11, 1995): 387. https://doi.org/10.1016/s0140-6736(95)90374-7.
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    • Breitner, J. C., and K. A. Welsh. “Diagnosis and management of memory loss and cognitive disorders among elderly persons.” Psychiatr Serv 46, no. 1 (January 1995): 29–35. https://doi.org/10.1176/ps.46.1.29.
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    • Breitner, J. C., and K. A. Welsh. “Genes and recent developments in the epidemiology of Alzheimer's disease and related dementia.” Epidemiol Rev 17, no. 1 (1995): 39–47. https://doi.org/10.1093/oxfordjournals.epirev.a036184.
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    • Breitner, J. C., K. A. Welsh, M. J. Helms, P. C. Gaskell, B. A. Gau, A. D. Roses, M. A. Pericak-Vance, and A. M. Saunders. “Delayed onset of Alzheimer's disease with nonsteroidal anti-inflammatory and histamine H2 blocking drugs.” Neurobiol Aging 16, no. 4 (1995): 523–30. https://doi.org/10.1016/0197-4580(95)00049-k.
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    • Norton, M. C., J. C. Breitner, K. A. Welsh, and B. W. Wyse. “Characteristics of nonresponders in a community survey of the elderly.” J Am Geriatr Soc 42, no. 12 (December 1994): 1252–56. https://doi.org/10.1111/j.1532-5415.1994.tb06506.x.
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    • Reed, T., D. Carmelli, G. E. Swan, J. C. Breitner, K. A. Welsh, G. P. Jarvik, S. Deeb, and J. Auwerx. “Lower cognitive performance in normal older adult male twins carrying the apolipoprotein E epsilon 4 allele.” Arch Neurol 51, no. 12 (December 1994): 1189–92. https://doi.org/10.1001/archneur.1994.00540240033012.
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    • Welsh, K. A., J. M. Hoffman, N. L. Earl, and M. W. Hanson. “Neural correlates of dementia: regional brain metabolism (FDG-PET) and the CERAD neuropsychological battery.” Arch Clin Neuropsychol 9, no. 5 (October 1994): 395–409.
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    • Fillenbaum, G. G., W. E. Wilkinson, K. A. Welsh, and R. C. Mohs. “Discrimination between stages of Alzheimer's disease with subsets of Mini-Mental State Examination items. An analysis of Consortium to Establish a Registry for Alzheimer's Disease data.” Arch Neurol 51, no. 9 (September 1994): 916–21. https://doi.org/10.1001/archneur.1994.00540210088017.
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    • Siegler, I. C., D. V. Dawson, and K. A. Welsh. “Caregiver ratings of personality change in Alzheimer's disease patients: a replication.” Psychol Aging 9, no. 3 (September 1994): 464–66. https://doi.org/10.1037//0882-7974.9.3.464.
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    • Welsh, K. A., N. Butters, R. C. Mohs, D. Beekly, S. Edland, G. Fillenbaum, and A. Heyman. “The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part V. A normative study of the neuropsychological battery.” Neurology 44, no. 4 (April 1994): 609–14. https://doi.org/10.1212/wnl.44.4.609.
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    • Breitner, J. C., B. A. Gau, K. A. Welsh, B. L. Plassman, W. M. McDonald, M. J. Helms, and J. C. Anthony. “Inverse association of anti-inflammatory treatments and Alzheimer's disease: initial results of a co-twin control study.” Neurology 44, no. 2 (February 1994): 227–32. https://doi.org/10.1212/wnl.44.2.227.
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    • Plassman, B. L., T. T. Newman, K. A. Welsh, M. Helms, and J. C. S. Breitner. “Properties of the telephone interview for cognitive status: Application in epidemiological and longitudinal studies.” Neuropsychiatry, Neuropsychology and Behavioral Neurology 7, no. 3 (January 1, 1994): 235–41.
    • Breitner, J. C., K. A. Welsh, C. D. Robinette, B. A. Gau, M. F. Folstein, and J. Brandt. “Alzheimer's disease in the NAS-NRC registry of aging twin veterans. II. Longitudinal findings in a pilot series. National Academy of Sciences. National Research Council Registry.” Dementia 5, no. 2 (1994): 99–105. https://doi.org/10.1159/000106703.
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    • Welsh, Kathleen A., Edna Ballard, Florence Nash, Kate Raiford, and Lindy Harrell. “Issues affecting minority participation in research studies of Alzheimer disease.” Alzheimer Dis Assoc Disord 8, no. Suppl. 4 (1994): 38–48.
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    • Brandt, J., K. A. Welsh, J. C. Breitner, M. F. Folstein, M. Helms, and J. C. Christian. “Hereditary influences on cognitive functioning in older men. A study of 4000 twin pairs.” Arch Neurol 50, no. 6 (June 1993): 599–603. https://doi.org/10.1001/archneur.1993.00540060039014.
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    • Breitner, J. C., M. Gatz, A. L. Bergem, J. C. Christian, J. A. Mortimer, G. E. McClearn, L. L. Heston, K. A. Welsh, J. C. Anthony, and M. F. Folstein. “Use of twin cohorts for research in Alzheimer's disease.” Neurology 43, no. 2 (February 1993): 261–67. https://doi.org/10.1212/wnl.43.2.261.
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    • Welsh, K. A., J. C. S. Breitner, and K. M. Magruder-Habib. “Detection of dementia in the elderly using telephone screening of cognitive status.” Neuropsychiatry, Neuropsychology and Behavioral Neurology 6, no. 2 (January 1, 1993): 103–10.
    • Welsh, K. A., J. M. Hoffman, W. M. McDonald, N. L. Earl, and J. C. S. Breitner. “Concordant but Different: Cognitive Function, Cerebral Anatomy, and Metabolism in Monozygotic Twins With Alzheimer's Disease.” Neuropsychology 7, no. 2 (January 1, 1993): 158–71. https://doi.org/10.1037/0894-4105.7.2.158.
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    • Welsh, K. A., N. Butters, J. P. Hughes, R. C. Mohs, and A. Heyman. “Detection and staging of dementia in Alzheimer's disease. Use of the neuropsychological measures developed for the Consortium to Establish a Registry for Alzheimer's Disease.” Arch Neurol 49, no. 5 (May 1992): 448–52. https://doi.org/10.1001/archneur.1992.00530290030008.
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    • Pericak-Vance, M. A., J. L. Bebout, P. C. Gaskell, L. H. Yamaoka, W. Y. Hung, M. J. Alberts, A. P. Walker, R. J. Bartlett, C. A. Haynes, and K. A. Welsh. “Linkage studies in familial Alzheimer disease: evidence for chromosome 19 linkage.” Am J Hum Genet 48, no. 6 (June 1991): 1034–50.
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    • Schellenberg, G. D., M. A. Pericak-Vance, E. M. Wijsman, D. K. Moore, P. C. Gaskell, L. A. Yamaoka, J. L. Bebout, L. Anderson, K. A. Welsh, and C. M. Clark. “Linkage analysis of familial Alzheimer disease, using chromosome 21 markers.” Am J Hum Genet 48, no. 3 (March 1991): 563–83.
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    • Welsh, K., N. Butters, J. Hughes, R. Mohs, and A. Heyman. “Detection of abnormal memory decline in mild cases of Alzheimer's disease using CERAD neuropsychological measures.” Arch Neurol 48, no. 3 (March 1991): 278–81. https://doi.org/10.1001/archneur.1991.00530150046016.
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    • Siegler, I. C., K. A. Welsh, D. V. Dawson, G. G. Fillenbaum, N. L. Earl, E. B. Kaplan, and C. M. Clark. “Ratings of personality change in patients being evaluated for memory disorders.” Alzheimer Dis Assoc Disord 5, no. 4 (1991): 240–50. https://doi.org/10.1097/00002093-199100540-00003.
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    • Welsh, K. A. “Detection of early dementia in the elderly.” Experimental Aging Research 17, no. 2 (1991): 101-.
    • Breitner, J. C. S., K. A. Welsh, K. M. Magruder-Habib, C. M. Churchill, C. D. Robinette, M. F. Folslein, E. A. Murphy, C. C. Priolo, and J. Brandt. “Alzheimer’s disease in the national academy of sciences registry of aging twin veterans: I. Pilot investigations.” Dementia and Geriatric Cognitive Disorders 1, no. 6 (January 1, 1990): 297–303. https://doi.org/10.1159/000107157.
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    • Pericak-Vance, M. A., J. L. Bebout, L. A. Yamaoka, P. C. Gaskell, W. Y. Hung, M. J. Alberts, C. M. Clark, et al. “Linkage studies in familial Alzheimer's disease, application of the affected pedigree member (APM) method of linkage analysis.” Molecular Biology and Genetics of Alzheimer’S Disease: Proceedings of the International Symposium on Dementia: Molecular Biology and Genetics of Alzheimer’S Disease. Ics884, January 1, 1990, 215–28.
    • Gold, P. E., and K. A. Welsh. “Regional brain catecholamines and memory: effects of footshock, amygdala implantation, and stimulation.” Behav Neural Biol 47, no. 2 (March 1987): 116–29. https://doi.org/10.1016/s0163-1047(87)90215-9.
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    • Welsh, K. A., and P. E. Gold. “Epinephrine proactive retardation of amygdala-kindled epileptogenesis.” Behav Neurosci 100, no. 2 (April 1986): 236–45. https://doi.org/10.1037//0735-7044.100.2.236.
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    • Welsh, K. A., and P. E. Gold. “Brain catecholamines and memory modulation: effects of footshock, amygdala implantation, and stimulation.” Behav Neural Biol 43, no. 2 (March 1985): 119–31. https://doi.org/10.1016/s0163-1047(85)91317-2.
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    • Welsh, K. A., and P. E. Gold. “Attenuation of epileptogenesis: proactive effect of a single epinephrine injection of amygdaloid kindling.” Behav Neural Biol 40, no. 2 (March 1984): 179–85. https://doi.org/10.1016/s0163-1047(84)90279-6.
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    • Welsh, K. A., and P. E. Gold. “Age-related changes in brain catecholamine responses to a single footshock.” Neurobiol Aging 5, no. 1 (1984): 55–59. https://doi.org/10.1016/0197-4580(84)90086-1.
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  • Book Sections

    • Welsh-Bohmer, K. A., and S. Johnson. “Neuropsychological Assessment of Dementia.” In Handbook of Dementing Illnesses, Second Edition, 59–87, 2006. https://doi.org/10.3109/9780849354847-8.
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  • Other Articles

    • Mackensen, G. B., L. K. Ti, B. G. Phillips-Bute, J. P. Mathew, M. F. Newman, H. P. Grocott, and H. P. Neurologic Outcome Research Group (NORG). “Cerebral embolization during cardiac surgery: impact of aortic atheroma burden.” Br J Anaesth, November 2003. https://doi.org/10.1093/bja/aeg234.
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    • Swaminathan, Madhav, Brian J. McCreath, Barbara G. Phillips-Bute, Mark F. Newman, Joseph P. Mathew, Peter K. Smith, James A. Blumenthal, Mark Stafford-Smith, and Mark Perioperative Outcomes Research Group. “Serum creatinine patterns in coronary bypass surgery patients with and without postoperative cognitive dysfunction.” Anesth Analg, July 2002. https://doi.org/10.1097/00000539-200207000-00001.
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  • Conference Papers

    • Aisen, P., J. Touchon, R. Amariglio, S. Andrieu, R. Bateman, J. Breitner, M. Donohue, et al. “EU/US/CTAD Task Force: Lessons Learned from Recent and Current Alzheimer's Prevention Trials.” In J Prev Alzheimers Dis, 4:116–24, 2017. https://doi.org/10.14283/jpad.2017.13.
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