Overview
Major focus is in three areas: epidemiology of dementia, assessment of functional status in the elderly, and pharmacoepidemiology.
With respect to the epidemiology of dementia I am running a major survey to determine the prevalence and incidence of Alzheimer's disease and other dementias in black and white elderly community residents. In addition to determining age-, sex-, and race-specific rates, risk factors for these conditions are being determined. Attempts are underway to improve …
With respect to the epidemiology of dementia I am running a major survey to determine the prevalence and incidence of Alzheimer's disease and other dementias in black and white elderly community residents. In addition to determining age-, sex-, and race-specific rates, risk factors for these conditions are being determined. Attempts are underway to improve …
Current Appointments & Affiliations
Professor Emeritus in Psychiatry and Behavioral Sciences
·
2015 - Present
Psychiatry & Behavioral Sciences, Adult Psychiatry & Psychology,
Psychiatry & Behavioral Sciences
Senior Fellow in the Center for the Study of Aging and Human Development
·
1975 - Present
Center for the Study of Aging and Human Development,
Institutes and Centers
Recent Publications
Machine learning functional impairment classification with electronic health record data.
Journal Article J Am Geriatr Soc · September 2023 BACKGROUND: Poor functional status is a key marker of morbidity, yet is not routinely captured in clinical encounters. We developed and evaluated the accuracy of a machine learning algorithm that leveraged electronic health record (EHR) data to provide a s ... Full text Open Access Link to item CiteCERAD (Consortium to Establish a Registry for Alzheimer's Disease) Neuropsychology Assessment Battery: 35 Years and Counting.
Journal Article J Alzheimers Dis · 2023 BACKGROUND: In 1986, the Consortium to Establish a Registry for Alzheimer's Disease (CERAD) was mandated to develop a brief neuropsychological assessment battery (CERAD-NAB) for AD, for uniform neuropsychological assessment, and information aggregation. In ... Full text Link to item CiteCausal analysis identifies small HDL particles and physical activity as key determinants of longevity of older adults.
Journal Article EBioMedicine · November 2022 BACKGROUND: The hard endpoint of death is one of the most significant outcomes in both clinical practice and research settings. Our goal was to discover direct causes of longevity from medically accessible data. METHODS: Using a framework that combines loc ... Full text Link to item CiteRecent Grants
Epigenetic Mechanisms Promoting Longevity
ResearchInvestigator · Awarded by National Institutes of Health · 2018 - 2024Behavior And Physiology In Aging
Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 1999 - 2015Trend and Trajectories of Oral Health among Older Americans
ResearchInvestigator · Awarded by National Institutes of Health · 2009 - 2014View All Grants
Education, Training & Certifications
University of London (United Kingdom) ·
1966
Ph.D.