On the reaction of ferric heme proteins with nitrite and sulfite.
Journal Article (Journal Article)
Optical and EPR spectroscopy of ferric heme proteins of the porphyrin, oxyporphyrin, and isobacteriochlorin classes has indicated that nitrite reacts with these proteins at the heme iron. Sulfite has been conclusively proven to react only with proteins containing the isobacteriochlorin macrocycle. Quantitative EPR spectroscopy of these nitrite and sulfite adducts showed that most contained a substantial quantity of undetectable heme. It is suggested that protein-induced autoreduction of nitrite (but not sulfite) and a strained and/or uniaxial g-tensor are the principal ways by which the silent state is produced.
Full Text
Duke Authors
Cited Authors
- Young, LJ; Siegel, LM
Published Date
- April 19, 1988
Published In
Volume / Issue
- 27 / 8
Start / End Page
- 2790 - 2800
PubMed ID
- 2840947
Pubmed Central ID
- 2840947
International Standard Serial Number (ISSN)
- 0006-2960
Digital Object Identifier (DOI)
- 10.1021/bi00408a020
Language
- eng
Conference Location
- United States