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On the reaction of ferric heme proteins with nitrite and sulfite.

Publication ,  Journal Article
Young, LJ; Siegel, LM
Published in: Biochemistry
April 19, 1988

Optical and EPR spectroscopy of ferric heme proteins of the porphyrin, oxyporphyrin, and isobacteriochlorin classes has indicated that nitrite reacts with these proteins at the heme iron. Sulfite has been conclusively proven to react only with proteins containing the isobacteriochlorin macrocycle. Quantitative EPR spectroscopy of these nitrite and sulfite adducts showed that most contained a substantial quantity of undetectable heme. It is suggested that protein-induced autoreduction of nitrite (but not sulfite) and a strained and/or uniaxial g-tensor are the principal ways by which the silent state is produced.

Duke Scholars

Published In

Biochemistry

DOI

ISSN

0006-2960

Publication Date

April 19, 1988

Volume

27

Issue

8

Start / End Page

2790 / 2800

Location

United States

Related Subject Headings

  • Sulfites
  • Spectrophotometry
  • Oxidation-Reduction
  • Nitrites
  • Kinetics
  • Hemeproteins
  • Heme
  • Electron Spin Resonance Spectroscopy
  • Biochemistry & Molecular Biology
  • 3404 Medicinal and biomolecular chemistry
 

Citation

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MLA
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Young, L. J., & Siegel, L. M. (1988). On the reaction of ferric heme proteins with nitrite and sulfite. Biochemistry, 27(8), 2790–2800. https://doi.org/10.1021/bi00408a020
Young, L. J., and L. M. Siegel. “On the reaction of ferric heme proteins with nitrite and sulfite.Biochemistry 27, no. 8 (April 19, 1988): 2790–2800. https://doi.org/10.1021/bi00408a020.
Young LJ, Siegel LM. On the reaction of ferric heme proteins with nitrite and sulfite. Biochemistry. 1988 Apr 19;27(8):2790–800.
Young, L. J., and L. M. Siegel. “On the reaction of ferric heme proteins with nitrite and sulfite.Biochemistry, vol. 27, no. 8, Apr. 1988, pp. 2790–800. Pubmed, doi:10.1021/bi00408a020.
Young LJ, Siegel LM. On the reaction of ferric heme proteins with nitrite and sulfite. Biochemistry. 1988 Apr 19;27(8):2790–2800.
Journal cover image

Published In

Biochemistry

DOI

ISSN

0006-2960

Publication Date

April 19, 1988

Volume

27

Issue

8

Start / End Page

2790 / 2800

Location

United States

Related Subject Headings

  • Sulfites
  • Spectrophotometry
  • Oxidation-Reduction
  • Nitrites
  • Kinetics
  • Hemeproteins
  • Heme
  • Electron Spin Resonance Spectroscopy
  • Biochemistry & Molecular Biology
  • 3404 Medicinal and biomolecular chemistry