Gustatory and reward brain circuits in the control of food intake.

Journal Article (Journal Article;Review)

Gustation is a multisensory process allowing for the selection of nutrients and the rejection of irritating and/or toxic compounds. Since obesity is a highly prevalent condition that is critically dependent on food intake and energy expenditure, a deeper understanding of gustatory processing is an important objective in biomedical research. Recent findings have provided evidence that central gustatory processes are distributed across several cortical and subcortical brain areas. Furthermore, these gustatory sensory circuits are closely related to the circuits that process reward. Here, we present an overview of the activation and connectivity between central gustatory and reward areas. Moreover, and given the limitations in number and effectiveness of treatments currently available for overweight patients, we discuss the possibility of modulating neuronal activity in these circuits as an alternative in the treatment of obesity.

Full Text

Duke Authors

Cited Authors

  • Oliveira-Maia, AJ; Roberts, CD; Simon, SA; Nicolelis, MAL

Published Date

  • 2011

Published In

Volume / Issue

  • 36 /

Start / End Page

  • 31 - 59

PubMed ID

  • 21197607

Pubmed Central ID

  • PMC3434955

International Standard Serial Number (ISSN)

  • 0095-4829

Digital Object Identifier (DOI)

  • 10.1007/978-3-7091-0179-7_3


  • eng

Conference Location

  • United States