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Miguel Angelo L. Nicolelis

Professor Emeritus of Neurobiology
Neurobiology
Gsrbii 210 Research Drive, Box 103905 Room 4028, Durham, NC 27710
Gsrbii 210 Research Drive, Box 103905 Room 4028, Durham, NC 27710

Overview


Miguel Nicolelis, M.D., Ph.D., is the Duke School of Medicine Distinguished Professor of Neuroscience, Duke University Professor of Neurobiology, Biomedical Engineering and Psychology and Neuroscience, and founder of Duke's Center for Neuroengineering. He is the founder and Scientific Director of the Edmond and Lily Safra International Institute for Neuroscience of Natal.  Dr. Nicolelis is also founder of the Walk Again Project, an international consortium of scientists and engineers, dedicated to the development of an exoskeleton device to assist severely paralyzed patients in regaining full body mobility.

Dr. Nicolelis has dedicated his career to investigate how the brains of freely behaving animals encode sensory and motor information. As a result of his studies, Dr. Nicolelis was first to propose and demonstrate that animals and human subjects can utilize their electrical brain activity to directly control neuroprosthetic devices via brain-machine interfaces (BMI).

Over the past 25 years, Dr. Nicolelis pioneered and perfected the development of a new neurophysiological method, known today as chronic, multi-site, multi-electrode recordings. Using this approach in a variety of animal species, as well as in intra-operative procedures in human patients, Dr. Nicolelis launched a new field of investigation, which aims at measuring the concurrent activity and interactions of large populations of single neurons throughout the brain. Through his work, Dr. Nicolelis has discovered a series of key physiological principles that govern the operation of mammalian brain circuits.

Dr. Nicolelis pioneering BMI studies have become extremely influential since they offer new potential therapies for patients suffering from severe levels of paralysis, Parkinson’s disease, and epilepsy. Today, numerous neuroscience laboratories in the US, Europe, Asia, and Latin America have incorporated Dr. Nicolelis' experimental paradigm to study a variety of mammalian neuronal systems. His research has influenced basic and applied research in computer science, robotics, and biomedical engineering. 

Current Appointments & Affiliations


Professor Emeritus of Neurobiology · 2021 - Present Neurobiology, Basic Science Departments

In the News


Published March 29, 2018
Monkeys' Brains Synchronize As They Collaborate To Perform A Motor Task
Published November 8, 2016
Brain-Machine Interface Helps Patients With Severe Spinal Cord Injuries Restore Some Mobility
Published August 12, 2016
Breakthrough for paralyzed patients

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Recent Publications


Training with noninvasive brain-machine interface, tactile feedback, and locomotion to enhance neurological recovery in individuals with complete paraplegia: a randomized pilot study.

Journal Article Sci Rep · November 29, 2022 In recent years, our group and others have reported multiple cases of consistent neurological recovery in people with spinal cord injury (SCI) following a protocol that integrates locomotion training with brain machine interfaces (BMI). The primary objecti ... Full text Link to item Cite
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Recent Grants


Basic predoctoral training in neuroscience

Inst. Training Prgm or CMETraining Faculty · Awarded by National Institutes of Health · 1992 - 2018

Path Toward MRI with Direct Sensitivity to Neuro-Electro-Magnetic Oscillations

ResearchCo Investigator · Awarded by National Institutes of Health · 2014 - 2018

Autism as a Disease of Brain Circuit Timing

ResearchPrincipal Investigator · Awarded by Hartwell Foundation · 2014 - 2017

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Education, Training & Certifications


University of Sao Paulo (Brazil) · 1988 Ph.D.
University of Sao Paulo (Brazil) · 1984 M.D.