Overview
Miguel Nicolelis, M.D., Ph.D., is the Duke School of Medicine Distinguished Professor of Neuroscience, Duke University Professor of Neurobiology, Biomedical Engineering and Psychology and Neuroscience, and founder of Duke's Center for Neuroengineering. He is the founder and Scientific Director of the Edmond and Lily Safra International Institute for Neuroscience of Natal. Dr. Nicolelis is also founder of the Walk Again Project, an international consortium of scientists and engineers, dedicated to the development of an exoskeleton device to assist severely paralyzed patients in regaining full body mobility.
Dr. Nicolelis has dedicated his career to investigate how the brains of freely behaving animals encode sensory and motor information. As a result of his studies, Dr. Nicolelis was first to propose and demonstrate that animals and human subjects can utilize their electrical brain activity to directly control neuroprosthetic devices via brain-machine interfaces (BMI).
Over the past 25 years, Dr. Nicolelis pioneered and perfected the development of a new neurophysiological method, known today as chronic, multi-site, multi-electrode recordings. Using this approach in a variety of animal species, as well as in intra-operative procedures in human patients, Dr. Nicolelis launched a new field of investigation, which aims at measuring the concurrent activity and interactions of large populations of single neurons throughout the brain. Through his work, Dr. Nicolelis has discovered a series of key physiological principles that govern the operation of mammalian brain circuits.
Dr. Nicolelis pioneering BMI studies have become extremely influential since they offer new potential therapies for patients suffering from severe levels of paralysis, Parkinson’s disease, and epilepsy. Today, numerous neuroscience laboratories in the US, Europe, Asia, and Latin America have incorporated Dr. Nicolelis' experimental paradigm to study a variety of mammalian neuronal systems. His research has influenced basic and applied research in computer science, robotics, and biomedical engineering.
Current Appointments & Affiliations
Recent Publications
Rethinking the neurosurgical approach to brain disorders from the network neuroscience perspective.
Journal Article Sci Bull (Beijing) · December 15, 2022 Full text Link to item CiteTraining with noninvasive brain-machine interface, tactile feedback, and locomotion to enhance neurological recovery in individuals with complete paraplegia: a randomized pilot study.
Journal Article Sci Rep · November 29, 2022 In recent years, our group and others have reported multiple cases of consistent neurological recovery in people with spinal cord injury (SCI) following a protocol that integrates locomotion training with brain machine interfaces (BMI). The primary objecti ... Full text Link to item CiteBrain-machine-brain interfaces as the foundation for the next generation of neuroprostheses.
Journal Article Natl Sci Rev · October 2022 Full text Link to item CiteRecent Grants
Basic predoctoral training in neuroscience
Inst. Training Prgm or CMETraining Faculty · Awarded by National Institutes of Health · 1992 - 2018Path Toward MRI with Direct Sensitivity to Neuro-Electro-Magnetic Oscillations
ResearchCo Investigator · Awarded by National Institutes of Health · 2014 - 2018Autism as a Disease of Brain Circuit Timing
ResearchPrincipal Investigator · Awarded by Hartwell Foundation · 2014 - 2017View All Grants