Tcf-3 expression and beta-catenin mediated transcriptional activation in aggressive fibromatosis (desmoid tumour).
Publication
, Journal Article
Tejpar, S; Li, C; Yu, C; Poon, R; Denys, H; Sciot, R; Van Cutsem, E; Cassiman, JJ; Alman, BA
Published in: Br J Cancer
July 6, 2001
Aggressive fibromatosis harbours mutations resulting in beta-catenin protein stabilization. Primary cell cultures demonstrate constitutive tcf activation in aggressive fibromatosis. Expression and co-immunoprecipitation studies suggest that beta-catenin binds and activates tcf-3 in this tumour. This is the first demonstration of tcf-3 activation by beta-catenin stabilization in a human neoplastic process.
Duke Scholars
Published In
Br J Cancer
DOI
ISSN
0007-0920
Publication Date
July 6, 2001
Volume
85
Issue
1
Start / End Page
98 / 101
Location
England
Related Subject Headings
- beta Catenin
- Tumor Cells, Cultured
- Transcriptional Activation
- Transcription Factors
- Transcription Factor 7-Like 1 Protein
- Trans-Activators
- TCF Transcription Factors
- Precipitin Tests
- Oncology & Carcinogenesis
- Humans
Citation
APA
Chicago
ICMJE
MLA
NLM
Tejpar, S., Li, C., Yu, C., Poon, R., Denys, H., Sciot, R., … Alman, B. A. (2001). Tcf-3 expression and beta-catenin mediated transcriptional activation in aggressive fibromatosis (desmoid tumour). Br J Cancer, 85(1), 98–101. https://doi.org/10.1054/bjoc.2001.1857
Tejpar, S., C. Li, C. Yu, R. Poon, H. Denys, R. Sciot, E. Van Cutsem, J. J. Cassiman, and B. A. Alman. “Tcf-3 expression and beta-catenin mediated transcriptional activation in aggressive fibromatosis (desmoid tumour).” Br J Cancer 85, no. 1 (July 6, 2001): 98–101. https://doi.org/10.1054/bjoc.2001.1857.
Tejpar S, Li C, Yu C, Poon R, Denys H, Sciot R, et al. Tcf-3 expression and beta-catenin mediated transcriptional activation in aggressive fibromatosis (desmoid tumour). Br J Cancer. 2001 Jul 6;85(1):98–101.
Tejpar, S., et al. “Tcf-3 expression and beta-catenin mediated transcriptional activation in aggressive fibromatosis (desmoid tumour).” Br J Cancer, vol. 85, no. 1, July 2001, pp. 98–101. Pubmed, doi:10.1054/bjoc.2001.1857.
Tejpar S, Li C, Yu C, Poon R, Denys H, Sciot R, Van Cutsem E, Cassiman JJ, Alman BA. Tcf-3 expression and beta-catenin mediated transcriptional activation in aggressive fibromatosis (desmoid tumour). Br J Cancer. 2001 Jul 6;85(1):98–101.
Published In
Br J Cancer
DOI
ISSN
0007-0920
Publication Date
July 6, 2001
Volume
85
Issue
1
Start / End Page
98 / 101
Location
England
Related Subject Headings
- beta Catenin
- Tumor Cells, Cultured
- Transcriptional Activation
- Transcription Factors
- Transcription Factor 7-Like 1 Protein
- Trans-Activators
- TCF Transcription Factors
- Precipitin Tests
- Oncology & Carcinogenesis
- Humans