Skip to main content
construction release_alert
Scholars@Duke will be undergoing maintenance April 11-15. Some features may be unavailable during this time.
cancel

Tcf-3 expression and beta-catenin mediated transcriptional activation in aggressive fibromatosis (desmoid tumour).

Publication ,  Journal Article
Tejpar, S; Li, C; Yu, C; Poon, R; Denys, H; Sciot, R; Van Cutsem, E; Cassiman, JJ; Alman, BA
Published in: Br J Cancer
July 6, 2001

Aggressive fibromatosis harbours mutations resulting in beta-catenin protein stabilization. Primary cell cultures demonstrate constitutive tcf activation in aggressive fibromatosis. Expression and co-immunoprecipitation studies suggest that beta-catenin binds and activates tcf-3 in this tumour. This is the first demonstration of tcf-3 activation by beta-catenin stabilization in a human neoplastic process.

Duke Scholars

Published In

Br J Cancer

DOI

ISSN

0007-0920

Publication Date

July 6, 2001

Volume

85

Issue

1

Start / End Page

98 / 101

Location

England

Related Subject Headings

  • beta Catenin
  • Tumor Cells, Cultured
  • Transcriptional Activation
  • Transcription Factors
  • Transcription Factor 7-Like 1 Protein
  • Trans-Activators
  • TCF Transcription Factors
  • Precipitin Tests
  • Oncology & Carcinogenesis
  • Humans
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Tejpar, S., Li, C., Yu, C., Poon, R., Denys, H., Sciot, R., … Alman, B. A. (2001). Tcf-3 expression and beta-catenin mediated transcriptional activation in aggressive fibromatosis (desmoid tumour). Br J Cancer, 85(1), 98–101. https://doi.org/10.1054/bjoc.2001.1857
Tejpar, S., C. Li, C. Yu, R. Poon, H. Denys, R. Sciot, E. Van Cutsem, J. J. Cassiman, and B. A. Alman. “Tcf-3 expression and beta-catenin mediated transcriptional activation in aggressive fibromatosis (desmoid tumour).Br J Cancer 85, no. 1 (July 6, 2001): 98–101. https://doi.org/10.1054/bjoc.2001.1857.
Tejpar S, Li C, Yu C, Poon R, Denys H, Sciot R, et al. Tcf-3 expression and beta-catenin mediated transcriptional activation in aggressive fibromatosis (desmoid tumour). Br J Cancer. 2001 Jul 6;85(1):98–101.
Tejpar, S., et al. “Tcf-3 expression and beta-catenin mediated transcriptional activation in aggressive fibromatosis (desmoid tumour).Br J Cancer, vol. 85, no. 1, July 2001, pp. 98–101. Pubmed, doi:10.1054/bjoc.2001.1857.
Tejpar S, Li C, Yu C, Poon R, Denys H, Sciot R, Van Cutsem E, Cassiman JJ, Alman BA. Tcf-3 expression and beta-catenin mediated transcriptional activation in aggressive fibromatosis (desmoid tumour). Br J Cancer. 2001 Jul 6;85(1):98–101.

Published In

Br J Cancer

DOI

ISSN

0007-0920

Publication Date

July 6, 2001

Volume

85

Issue

1

Start / End Page

98 / 101

Location

England

Related Subject Headings

  • beta Catenin
  • Tumor Cells, Cultured
  • Transcriptional Activation
  • Transcription Factors
  • Transcription Factor 7-Like 1 Protein
  • Trans-Activators
  • TCF Transcription Factors
  • Precipitin Tests
  • Oncology & Carcinogenesis
  • Humans