Recovery and survival from aging-associated diseases.

Journal Article (Journal Article)

OBJECTIVES: Considering disease incidence to be a main contributor to healthy lifespan of the US elderly population may lead to erroneous conclusions when recovery/long-term remission factors are underestimated. Using two Medicare-based population datasets, we investigated the properties of recovery from eleven age-related diseases. METHODS: Cohorts of patients who stopped visiting doctors during a five-year follow-up since disease onset were analyzed non-parametrically and using the Cox proportional hazard model resulted in estimated recovery and survival rates and evaluated the health state of recovered individuals by comparing their survival with non-recovered patients and the general population. RESULTS: Recovered individuals had lower death rates than non-recovered patients, therefore, patients who stopped visiting doctors are a healthier subcohort. However, they had higher death rates than in general population for all considered diseases, therefore the complete recovery does not occur. CONCLUSION: Properties of recovery/long-term remission among the US population of older adults with chronic diseases were uncovered and evaluated. The results allow for a better quantifiable contribution of age-related diseases to healthy life expectancy and improving forecasts of health and mortality.

Full Text

Duke Authors

Cited Authors

  • Akushevich, I; Kravchenko, J; Ukraintseva, S; Arbeev, K; Yashin, AI

Published Date

  • August 2013

Published In

Volume / Issue

  • 48 / 8

Start / End Page

  • 824 - 830

PubMed ID

  • 23707929

Pubmed Central ID

  • PMC3723111

Electronic International Standard Serial Number (EISSN)

  • 1873-6815

Digital Object Identifier (DOI)

  • 10.1016/j.exger.2013.05.056


  • eng

Conference Location

  • England