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Anatoli I. Yashin

Research Professor in the Social Science Research Institute
Social Science Research Institute
Duke Box 90420, Durham, NC 27708-0408
2024 W. Main Street, Durham, NC 27705

Current Appointments & Affiliations


Research Professor in the Social Science Research Institute · 2011 - Present Social Science Research Institute, University Institutes and Centers
Member of the Duke Cancer Institute · 1992 - Present Duke Cancer Institute, Institutes and Centers
Faculty Research Scholar of DuPRI's Population Research Center · 2010 - Present Duke Population Research Center, Duke Population Research Institute
Faculty Research Scholar of DuPRI's Center for Population Health & Aging · 2011 - Present Center for Population Health & Aging, Duke Population Research Institute

Recent Publications


Evidence of a novel gene locus <i>ARHGAP44</i> for longitudinal change in hemoglobin A1c levels among subjects without diabetes from the Long Life Family Study.

Journal Article Physiological genomics · May 2025 Glycated hemoglobin A1c (HbA1c) indicates average glucose levels over 3 mo and is associated with insulin resistance and type 2 diabetes (T2D). Longitudinal change in circulating HbA1c (ΔHbA1c) is also associated with aging processes, cognitive performance ... Full text Cite

Basic Science and Pathogenesis

Journal Article Alzheimer's & dementia : the journal of the Alzheimer's Association · December 1, 2024 BACKGROUND: Results of recent analyses indicate that axon demyelination may play an important role in AD pathology. The MBP gene encodes a myelin basic protein involved in axon myelination in the nervous system including the central nervous system. Polymor ... Full text Cite

Whole genome-wide sequence analysis of long-lived families (Long-Life Family Study) identifies MTUS2 gene associated with late-onset Alzheimer's disease.

Journal Article Alzheimer's & dementia : the journal of the Alzheimer's Association · April 2024 IntroductionLate-onset Alzheimer's disease (LOAD) has a strong genetic component. Participants in Long-Life Family Study (LLFS) exhibit delayed onset of dementia, offering a unique opportunity to investigate LOAD genetics.MethodsWe conduc ... Full text Cite
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Recent Grants


Dissecting genetic and non-genetic heterogeneity in predisposition to Alzheimer's disease and vascular traits in pleiotropic context

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2020 - 2026

Project 1: The Long Life Family Study

ResearchPrincipal Investigator · Awarded by Washington University in St. Louis · 2019 - 2026

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Education, Training & Certifications


Moscow Institute of Physics and Technology (Russia) · 1970 Ph.D.
Moscow Institute of Physics and Technology (Russia) · 1967 M.S.