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Svati Hasmukh Shah

Ursula Geller Distinguished Professor of Research in Cardiovascular Diseases
Medicine, Cardiology
Duke Box 104775, Durham, NC 27701
DUMC Box 3445, Durham, NC 27710

Current Appointments & Affiliations


Ursula Geller Distinguished Professor of Research in Cardiovascular Diseases · 2023 - Present Medicine, Cardiology, Medicine
Professor of Medicine · 2019 - Present Medicine, Cardiology, Medicine
Associate Dean for Translational Research · 2024 - Present School of Medicine
Professor of Biostatistics and Bioinformatics · 2022 - Present Biostatistics & Bioinformatics, Division of Translational Biomedical, Biostatistics & Bioinformatics
Member in the Duke Clinical Research Institute · 2010 - Present Duke Clinical Research Institute, Institutes and Centers
Member of Duke Molecular Physiology Institute · 2013 - Present Duke Molecular Physiology Institute, Institutes and Centers

In the News


Published September 25, 2023
Heartfelt Gratitude: Duke Patient Contributes to OneDukeGen Study
Published September 12, 2023
New Center for Precision Health Aims to Transform Population Health, Patient Care
Published June 28, 2023
New, Early Marker for Heart Disease Discovered

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Recent Publications


Digital Strategies for Recruitment to Improve Diversity and Inclusion in Prospective Cardiovascular Clinical Research.

Journal Article Cardiol Ther · December 2025 INTRODUCTION: Cardiovascular trials often underrepresent non-White participants, women, and older individuals. METHODS: We evaluated the impact of digital recruitment on improving diversity in two large prospective cardiovascular studies: the Apple Heart S ... Full text Link to item Cite

Rationale and Design of the HeartShare/AMP-HF Deep Phenotyping Study to Improve Understanding of Heart Failure With Preserved Ejection Fraction.

Journal Article JACC Heart Fail · December 2025 Heart failure with preserved ejection fraction (HFpEF) has risen to become the most common form of heart failure (HF) worldwide. The pathophysiology of HFpEF is complex and intimately tied to cardiac-metabolic-kidney abnormalities, spanning cardiac, vascul ... Full text Link to item Cite

A gene regulatory element modulates myosin expression and controls cardiomyocyte response to stress.

Journal Article Genome Res · November 3, 2025 A hallmark of heart disease is gene dysregulation and reactivation of fetal gene programs. Reactivation of these fetal programs has compensatory effects during heart failure, depending on the type and stage of the underlying cardiomyopathy. Thousands of pu ... Full text Link to item Cite
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Recent Grants


1/3 CTSA UM1 at Duke University

ResearchCore Co-Lead · Awarded by National Institutes of Health · 2025 - 2032

iPediHeart: Interdisciplinary Research Training Program for Pediatric Heart Disease

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2025 - 2030

2/3 CTSA K12 Program at Duke University

ResearchMentor · Awarded by National Institutes of Health · 2025 - 2030

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Education, Training & Certifications


University of Washington · 1998 M.D.
Johns Hopkins University · 1994 M.H.S.