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Digital Strategies for Recruitment to Improve Diversity and Inclusion in Prospective Cardiovascular Clinical Research.

Publication ,  Journal Article
Jain, SS; Rodriguez, F; Perez, MV; Yu, J; Shashidhar, S; Swope, S; Nguyen, K; Desai, M; Hedlin, H; Shah, SH; Hernandez, AF; Turakhia, MP; Mahaffey, KW
Published in: Cardiol Ther
December 2025

INTRODUCTION: Cardiovascular trials often underrepresent non-White participants, women, and older individuals. METHODS: We evaluated the impact of digital recruitment on improving diversity in two large prospective cardiovascular studies: the Apple Heart Study (AHS) and the Project Baseline Health Study (PBHS). While both leveraged digital tools, their strategies differed-AHS used a passive, app-based approach followed by a direct-to-participant outreach effort, while PBHS implemented an enrollment model to reach a prespecified diversity goal. RESULTS: While both methods led to a cohort of participants who were comparably aligned with the US Census, we found that intentional, goal-driven digital outreach, and participant selection targeting demographic representation improved inclusion of historically underrepresented groups. CONCLUSIONS: These findings suggest that digital tools, when paired with intentional strategy, may help support more inclusive, representative cardiovascular research.

Duke Scholars

Published In

Cardiol Ther

DOI

ISSN

2193-8261

Publication Date

December 2025

Volume

14

Issue

4

Start / End Page

687 / 694

Location

England
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Jain, S. S., Rodriguez, F., Perez, M. V., Yu, J., Shashidhar, S., Swope, S., … Mahaffey, K. W. (2025). Digital Strategies for Recruitment to Improve Diversity and Inclusion in Prospective Cardiovascular Clinical Research. Cardiol Ther, 14(4), 687–694. https://doi.org/10.1007/s40119-025-00435-3
Jain, Sneha S., Fatima Rodriguez, Marco V. Perez, Jingzhi Yu, Sumana Shashidhar, Susan Swope, Kaylin Nguyen, et al. “Digital Strategies for Recruitment to Improve Diversity and Inclusion in Prospective Cardiovascular Clinical Research.Cardiol Ther 14, no. 4 (December 2025): 687–94. https://doi.org/10.1007/s40119-025-00435-3.
Jain SS, Rodriguez F, Perez MV, Yu J, Shashidhar S, Swope S, et al. Digital Strategies for Recruitment to Improve Diversity and Inclusion in Prospective Cardiovascular Clinical Research. Cardiol Ther. 2025 Dec;14(4):687–94.
Jain, Sneha S., et al. “Digital Strategies for Recruitment to Improve Diversity and Inclusion in Prospective Cardiovascular Clinical Research.Cardiol Ther, vol. 14, no. 4, Dec. 2025, pp. 687–94. Pubmed, doi:10.1007/s40119-025-00435-3.
Jain SS, Rodriguez F, Perez MV, Yu J, Shashidhar S, Swope S, Nguyen K, Desai M, Hedlin H, Shah SH, Hernandez AF, Turakhia MP, Mahaffey KW. Digital Strategies for Recruitment to Improve Diversity and Inclusion in Prospective Cardiovascular Clinical Research. Cardiol Ther. 2025 Dec;14(4):687–694.

Published In

Cardiol Ther

DOI

ISSN

2193-8261

Publication Date

December 2025

Volume

14

Issue

4

Start / End Page

687 / 694

Location

England