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Christoph Paul Vincent Hornik

Samuel L. Katz Distinguished Professor of Pediatrics
Pediatrics, Critical Care Medicine
DCRI PO Box 17969, Durham, NC 27715
Dept of Pediatrics, Durham, NC 27710

Current Appointments & Affiliations


Samuel L. Katz Distinguished Professor of Pediatrics · 2024 - Present Pediatrics, Critical Care Medicine, Pediatrics
Professor of Pediatrics · 2023 - Present Pediatrics, Critical Care Medicine, Pediatrics
Chief, Division of Quantitative Sciences · 2018 - Present Pediatrics, Clinical Science Departments
Vice-Chair for Research in the Department of Pediatrics · 2022 - Present Pediatrics, Clinical Science Departments
Membership in the Duke Clinical Research Institute · 2013 - Present Duke Clinical Research Institute, Institutes and Centers

In the News


Published July 3, 2025
Better Health for Teens Starts with Going Places in the Neighborhood
Published March 19, 2024
Duke Awards 32 New Distinguished Professorships for 2024
Published October 7, 2022
New DCRI Center Targets Ending Opioid Addiction

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Recent Publications


A Bayesian re-analysis of the STRESS trial.

Journal Article Am Heart J · February 2026 BACKGROUND: Prophylactic steroids are often used to reduce the systemic inflammatory response to cardiopulmonary bypass in infants undergoing heart surgery. The STRESS trial found that the odds of a worse outcome did not differ between infants randomized t ... Full text Link to item Cite

Population Pharmacokinetics to Support Intravenous and Enteral Methadone Dosing in Children.

Journal Article J Clin Pharmacol · January 2026 Methadone is used in hospitalized children to treat pain and iatrogenic opiate withdrawal. Optimal pediatric dosing for both enteral and intravenous methadone is unknown. We conducted two prospective, multi-center, open-label studies to characterize the ph ... Full text Link to item Cite

Machine Learning Risk Prediction for Treated Retinopathy of Prematurity in Infants.

Journal Article Neonatology · November 18, 2025 INTRODUCTION: Retinopathy of prematurity (ROP) is a leading cause of childhood blindness. However, current screening guidelines may be overly broad, necessitating better models to detect high-risk infants. METHODS: From a multicenter cohort of 103,701 infa ... Full text Link to item Cite
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Recent Grants


iPediHeart: Interdisciplinary Research Training Program for Pediatric Heart Disease

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2025 - 2030

2/3 CTSA K12 Program at Duke University

ResearchMentor · Awarded by National Institutes of Health · 2025 - 2030

Teams Engaged in Accessible Mental Health Interventions for Lupus Erythematosus and Dermatomyositis Stress

ResearchCo-Mentor · Awarded by National Institutes of Health · 2025 - 2030

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Education, Training & Certifications


University of North Carolina, Chapel Hill · 2019 Ph.D.
University of North Carolina, Chapel Hill · 2012 M.P.H.
Albert Ludwigs University of Freiburg (Germany) · 2005 M.D.