Current Appointments & Affiliations
George Barth Geller Distinguished Professor of Molecular Biology
·
2023 - Present
Biochemistry,
Basic Science Departments
Professor of Biochemistry
·
2020 - Present
Biochemistry,
Basic Science Departments
Professor of Cell Biology
·
2022 - Present
Cell Biology,
Basic Science Departments
Professor in Neurobiology
·
2024 - Present
Neurobiology,
Basic Science Departments
Member of the Duke Cancer Institute
·
2012 - Present
Duke Cancer Institute,
Institutes and Centers
Recent Publications
Design, Synthesis, and Biological Evaluation of Lipid-Modified Derivatives of Tunicamycins.
Journal Article Chemistry · October 22, 2025 Naturally occurring antibiotic tunicamycin targets bacterial peptidoglycan biosynthesis by inhibiting bacterial phospho-N-acetylmuraminic acid (MurNAc)-pentapeptide translocase (MraY), but it also inhibits human UDP-N-acetylglucosamine (GlcNAc): polyprenol ... Full text Link to item CiteMolecular basis of the urate transporter URAT1 inhibition by gout drugs.
Journal Article Nat Commun · June 4, 2025 Hyperuricemia is a condition when uric acid, a waste product of purine metabolism, accumulates in the blood. Untreated hyperuricemia can lead to crystal formation of monosodium urate in the joints, causing a painful inflammatory disease known as gout. Thes ... Full text Link to item CiteMolecular basis of neurosteroid and anticonvulsant regulation of TRPM3.
Journal Article Nat Struct Mol Biol · May 2025 Transient receptor potential channel subfamily M member 3 (TRPM3) is a Ca2+-permeable cation channel activated by the neurosteroid pregnenolone sulfate (PregS) or heat, serving as a nociceptor in the peripheral sensory system. Recent discoveries of autosom ... Full text Link to item CiteRecent Grants
Structure, function, and pharmacology of sensory receptors
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2024 - 2032Neurobiology Training Program
Inst. Training Prgm or CMEMentor · Awarded by National Institute of Neurological Disorders and Stroke · 2024 - 2029TRPM8 in eye health and disease
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2020 - 2029View All Grants
Education, Training & Certifications
University of California, Berkeley ·
2003
Ph.D.
Yonsei University (South Korea) ·
1998
B.S.