https://orcid.org/0000-0002-0662-9921
Current Appointments & Affiliations
George Barth Geller Distinguished Professor of Molecular Biology
·
2023 - Present
Biochemistry,
Basic Science Departments
Professor of Biochemistry
·
2020 - Present
Biochemistry,
Basic Science Departments
Professor of Cell Biology
·
2022 - Present
Cell Biology,
Basic Science Departments
Professor in Neurobiology
·
2024 - Present
Neurobiology,
Basic Science Departments
Member of the Duke Cancer Institute
·
2012 - Present
Duke Cancer Institute,
Institutes and Centers
Recent Publications
Visualizing insecticide control of insect TRP channel function and assembly.
Journal Article Nat Commun · December 14, 2025 Insecticides are vital to combating world food shortages and transmission of vector-borne human diseases. Increasing insecticide resistance necessitates discovery of novel compounds against underutilized targets. Nanchung (Nan) and Inactive (Iav), the tran ... Full text Link to item CiteDesign, Synthesis, and Biological Evaluation of Lipid-Modified Derivatives of Tunicamycins.
Journal Article Chemistry · October 22, 2025 Naturally occurring antibiotic tunicamycin targets bacterial peptidoglycan biosynthesis by inhibiting bacterial phospho-N-acetylmuraminic acid (MurNAc)-pentapeptide translocase (MraY), but it also inhibits human UDP-N-acetylglucosamine (GlcNAc): polyprenol ... Full text Link to item CiteMolecular basis of the urate transporter URAT1 inhibition by gout drugs.
Journal Article Nat Commun · June 4, 2025 Hyperuricemia is a condition when uric acid, a waste product of purine metabolism, accumulates in the blood. Untreated hyperuricemia can lead to crystal formation of monosodium urate in the joints, causing a painful inflammatory disease known as gout. Thes ... Full text Link to item CiteRecent Grants
Structure, function, and pharmacology of sensory receptors
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2024 - 2032Neurobiology Training Program
Inst. Training Prgm or CMEMentor · Awarded by National Institute of Neurological Disorders and Stroke · 2024 - 2029TRPM8 in eye health and disease
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2020 - 2029View All Grants
Education
University of California, Berkeley ·
2003
Ph.D.
Yonsei University (South Korea) ·
1998
B.S.