Scholars@Duke
Victor Louis Roggli

Victor Louis Roggli

Professor of Pathology
Pathology
Roggl002@mc.duke.edu
Duke Box 3712, Durham, NC 27710
M255 Davison Bldg, 200 Trent Drive, Durham, NC 27710

Overview

My laboratory continues its interest in analyzing lung tissue for its asbestos content and correlating these results with pathologic diagnoses and with exposure histories. Both concentrations of asbestos fibers and types of fibers present are determined by a combination of light microscopy and scanning electron microscopy equipped with an energy dispersive spectrometer. Studies are also performed on lung tissue from individuals with other types of occupational exposures, such as coal dust and silica. This primarily involves in situ analysis of particulates in tissue sections using a combination of scanning electron microscopy, back scattered electron imaging, and energy dispersive x-ray analysis. Similar technology is used to analyze urinary calculi and xenobiotics within tissue samples, such as silicone in breast implant capsules.
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Current Appointments & Affiliations

Professor of Pathology · 1994 - Present Pathology, Clinical Science Departments

In the News

Published January 5, 2026
From Patient to Pathologist

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Recent Publications

Coal dust complexes host cell iron to impact metal homeostasis and pneumoconiosis.

Journal Article Am J Physiol Lung Cell Mol Physiol · April 1, 2026 Surface complexation of cell iron following particle exposure can be relevant to coal mine dust lung disease. We tested the postulate that 1) coal dust and humic substances (HS), a specific component of coal, complex intracellular iron from cultured cells ... Full text Link to item Cite

An Evaluation Into the Robustness of Grading of Pleural Mesothelioma Outside of Specialist Centres.

Journal Article APMIS · March 2025 The 2021 WHO classification of thoracic tumours recommends grading pleural mesothelioma to aid prognostication. Robustness of grading and morphological characterisation is key to its clinical utility, though validation of this grading system has largely be ... Full text Link to item Cite

Recent trends in the causation of peritoneal mesothelioma: fiber burden analysis of ten cases.

Journal Article Ultrastruct Pathol · 2025 Mesothelioma in the past has been strongly associated with a history of asbestos exposure. Studies have shown that, on average, a higher dose of asbestos exposure is required for the development of peritoneal mesothelioma, and a smaller percentage of cases ... Full text Link to item Cite
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Education

Baylor University · 1976 M.D.
Rice University · 1973 B.A.