Victor Louis Roggli

My laboratory continues its interest in analyzing lung tissue for its asbestos content and correlating these results with pathologic diagnoses and with exposure histories. Both concentrations of asbestos fibers and types of fibers present are determined by a combination of light microscopy and scanning electron microscopy equipped with an energy dispersive spectrometer. Studies are also performed on lung tissue from individuals with other types of occupational exposures, such as coal dust and silica. This primarily involves in situ analysis of particulates in tissue sections using a combination of scanning electron microscopy, back scattered electron imaging, and energy dispersive x-ray analysis. Similar technology is used to analyze urinary calculi and xenobiotics within tissue samples, such as silicone in breast implant capsules.
.

Current Appointments & Affiliations

Professor of Pathology · 1994 - Present Pathology, Clinical Science Departments

Recent Publications

An Evaluation Into the Robustness of Grading of Pleural Mesothelioma Outside of Specialist Centres.

Journal Article APMIS · March 2025 The 2021 WHO classification of thoracic tumours recommends grading pleural mesothelioma to aid prognostication. Robustness of grading and morphological characterisation is key to its clinical utility, though validation of this grading system has largely be ... Full text Link to item Cite

Recent trends in the causation of peritoneal mesothelioma: fiber burden analysis of ten cases.

Journal Article Ultrastruct Pathol · 2025 Mesothelioma in the past has been strongly associated with a history of asbestos exposure. Studies have shown that, on average, a higher dose of asbestos exposure is required for the development of peritoneal mesothelioma, and a smaller percentage of cases ... Full text Link to item Cite

Cigarette smoking decreases macrophage-dependent clearance to impact the biological effects of occupational and environmental particle exposures.

Journal Article Front Public Health · 2025 The retention of occupational and environmental particles in the lung is a primary determinant of biological effects. In the distal respiratory tract, particle clearance includes phagocytosis by alveolar macrophages (AMs), migration to the terminal bronchi ... Full text Link to item Cite

View All Publications

Education, Training & Certifications

Baylor University · 1976 M.D.

Rice University · 1973 B.A.