Current Appointments & Affiliations
John W. Strohbehn Distinguished Professor of Biomedical Engineering
·
2021 - Present
Biomedical Engineering,
Pratt School of Engineering
Professor of Biomedical Engineering
·
2021 - Present
Biomedical Engineering,
Pratt School of Engineering
Associate Professor of Surgery
·
2019 - Present
Surgery, Surgical Sciences,
Surgery
Associate Professor in Orthopaedic Surgery
·
2015 - Present
Orthopaedic Surgery,
Clinical Science Departments
Associate Professor in Cell Biology
·
2020 - Present
Cell Biology,
Basic Science Departments
Professor in Molecular Genetics and Microbiology
·
2025 - Present
Molecular Genetics and Microbiology,
Basic Science Departments
Member of the Duke Cancer Institute
·
2013 - Present
Duke Cancer Institute,
Institutes and Centers
Associate of the Duke Initiative for Science & Society
·
2017 - Present
Duke Science & Society,
University Initiatives & Academic Support Units
Affiliate of the Duke Regeneration Center
·
2021 - Present
Duke Regeneration Center,
Basic Science Departments
Recent Publications
Monitoring biological effects of somatic cell genome editing.
Journal Article Nature reviews. Genetics · April 2026 CRISPR-based genome editing therapeutics are entering the clinic, offering transformative potential but also presenting potential risks. Preclinical-to-clinical toolkits are needed to assess the safety and efficacy of these new therapies and accelerate pro ... Full text CiteReprogramming of neuronal genome function and phenotype by astrocytes.
Journal Article bioRxiv · March 7, 2026 Heterotypic cell-cell interactions are critical to governing cellular physiology, disease progression, and responses to the environment and pharmacologic interventions. For example, neurons and astrocytes engage in intricate interactions that are essential ... Full text Link to item CitedHyperCas12a enables multiplexed CRISPRi screens.
Journal Article Nat Commun · February 12, 2026 Interactions between genes or cis-regulatory elements (CREs) underlie many biological processes. High-throughput CRISPR screens have allowed researchers to assess the impact of activation or repression of gene and regulatory elements on many phenotypes. Ho ... Full text Link to item CiteRecent Grants
Pharmacological Sciences Training Program
Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 2025 - 2030Chromatin dysregulation in neurodevelopmental disorders
ResearchCollaborator · Awarded by National Institute of Neurological Disorders and Stroke · 2024 - 2029Epigenetic Programming of T Cells for Enhanced Cellular Immunotherapy
ResearchPrincipal Investigator · Awarded by National Cancer Institute · 2024 - 2029View All Grants
Education
Georgia Institute of Technology ·
2006
Ph.D.
Georgia Institute of Technology ·
2001
B.S.