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Charles Gersbach

John W. Strohbehn Distinguished Professor of Biomedical Engineering
Biomedical Engineering
Box 90281, 136 Hudson Hall, Durham, NC 27708
2123 CIEMAS, Durham, NC 27708

Current Appointments & Affiliations


John W. Strohbehn Distinguished Professor of Biomedical Engineering · 2021 - Present Biomedical Engineering, Pratt School of Engineering
Professor of Biomedical Engineering · 2021 - Present Biomedical Engineering, Pratt School of Engineering
Associate Professor of Surgery · 2019 - Present Surgery, Surgical Sciences, Surgery
Associate Professor in Orthopaedic Surgery · 2015 - Present Orthopaedic Surgery, Clinical Science Departments
Associate Professor in Cell Biology · 2020 - Present Cell Biology, Basic Science Departments
Member of the Duke Cancer Institute · 2013 - Present Duke Cancer Institute, Institutes and Centers
Associate of the Duke Initiative for Science & Society · 2017 - Present Duke Science & Society, University Initiatives & Academic Support Units
Core Faculty in Innovation & Entrepreneurship · 2019 - Present Duke Innovation & Entrepreneurship, University Initiatives & Academic Support Units
Affiliate of the Duke Regeneration Center · 2021 - Present Duke Regeneration Center, Basic Science Departments

In the News


Published February 13, 2025
Activating Complex Regions of the Genome to Treat Rare Diseases
Published November 8, 2024
Genomic Medicine, Beyond CRISPR
Published October 2, 2024
Duke 100 Trailblazer: Charles Gersbach

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Recent Publications


Gene regulation technologies for gene and cell therapy.

Journal Article Molecular therapy : the journal of the American Society of Gene Therapy · May 2025 Gene therapy stands at the forefront of medical innovation, offering unique potential to treat the underlying causes of genetic disorders and broadly enable regenerative medicine. However, unregulated production of therapeutic genes can lead to decreased c ... Full text Cite
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Recent Grants


Chromatin dysregulation in neurodevelopmental disorders

ResearchCollaborator · Awarded by National Institute of Neurological Disorders and Stroke · 2024 - 2029

Epigenetic Programming of T Cells for Enhanced Cellular Immunotherapy

ResearchPrincipal Investigator · Awarded by National Cancer Institute · 2024 - 2029

Optimizing Gene Therapy for Respiratory Insufficiency in Duchenne Muscular Dystrophy

ResearchCo Investigator · Awarded by National Institutes of Health · 2024 - 2028

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Education, Training & Certifications


Georgia Institute of Technology · 2006 Ph.D.
Georgia Institute of Technology · 2001 B.S.