Current Appointments & Affiliations
John W. Strohbehn Distinguished Professor of Biomedical Engineering
·
2021 - Present
Biomedical Engineering,
Pratt School of Engineering
Professor of Biomedical Engineering
·
2021 - Present
Biomedical Engineering,
Pratt School of Engineering
Associate Professor of Surgery
·
2019 - Present
Surgery, Surgical Sciences,
Surgery
Associate Professor in Orthopaedic Surgery
·
2015 - Present
Orthopaedic Surgery,
Clinical Science Departments
Associate Professor in Cell Biology
·
2020 - Present
Cell Biology,
Basic Science Departments
Professor in Molecular Genetics and Microbiology
·
2025 - Present
Molecular Genetics and Microbiology,
Basic Science Departments
Member of the Duke Cancer Institute
·
2013 - Present
Duke Cancer Institute,
Institutes and Centers
Associate of the Duke Initiative for Science & Society
·
2017 - Present
Duke Science & Society,
University Initiatives & Academic Support Units
Affiliate of the Duke Regeneration Center
·
2021 - Present
Duke Regeneration Center,
Basic Science Departments
Recent Publications
A gene regulatory element modulates myosin expression and controls cardiomyocyte response to stress.
Journal Article Genome Res · October 22, 2025 A hallmark of heart disease is gene dysregulation and reactivation of fetal gene programs. Reactivation of these fetal programs has compensatory effects during heart failure, depending on the type and stage of the underlying cardiomyopathy. Thousands of pu ... Full text Link to item CiteMechanosensitive genomic enhancers potentiate the cellular response to matrix stiffness.
Journal Article Science · September 25, 2025 Epigenetic control of gene expression and cellular phenotype is influenced by changes in the local microenvironment, yet how mechanical cues precisely influence epigenetic state to regulate transcription remains largely unmapped. Here, we combine genome-wi ... Full text Link to item CiteA gene regulatory element modulates myosin expression and controls cardiomyocyte response to stress.
Journal Article bioRxiv · July 20, 2025 A hallmark of heart disease is gene dysregulation and reactivation of fetal gene programs. Reactivation of these fetal programs has compensatory effects during heart failure, depending on the type and stage of the underlying cardiomyopathy. Thousands of pu ... Full text Link to item CiteRecent Grants
Pharmacological Sciences Training Program
Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 2025 - 2030Chromatin dysregulation in neurodevelopmental disorders
ResearchCollaborator · Awarded by National Institute of Neurological Disorders and Stroke · 2024 - 2029Epigenetic Programming of T Cells for Enhanced Cellular Immunotherapy
ResearchPrincipal Investigator · Awarded by National Cancer Institute · 2024 - 2029View All Grants
Education, Training & Certifications
Georgia Institute of Technology ·
2006
Ph.D.
Georgia Institute of Technology ·
2001
B.S.