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Risk factors for exposure of glaucoma drainage devices: a retrospective observational study.

Publication ,  Journal Article
Muir, KW; Lim, A; Stinnett, S; Kuo, A; Tseng, H; Walsh, MM
Published in: BMJ Open
May 2, 2014

OBJECTIVES: The purpose of this study was to identify risk factors for exposure of glaucoma drainage devices (GDD). SETTING: This retrospective, observational study was conducted in the eye clinic of an academic medical centre. PARTICIPANTS: Participants included 1073 consecutive adults who underwent GDD surgery between 1 January 2005 and 1 January 2011. Participants were included if chart review indicated GDD surgery during the study period and excluded if at least 12 months of clinical follow-up was not available in the medical record. PRIMARY OUTCOME MEASURE: The primary outcome measure was exposure of the GDD occurring at least 1 month after implant surgery. The characteristics of participants who experienced exposure of the implant were compared to the characteristics of participants who did not experience exposure. RESULTS: Of the 1073 participants having undergone GDD surgery, 67 experienced exposure of the device. Neither the type of GDD, type of patch graft (eye bank sclera, Tutoplast sclera and Tutoplast pericardium), surgeon, location of GDD, number of GDD previously implanted into the eye, nor history of diabetes or uveitis were associated with likelihood of exposure. Women were more likely than men to experience exposure of the GDD (OR 2.004 (95% CI1.170 to 3.431)) in both univariable (p=0.011) and multivariable (p=0.013) analyses. In survival analysis, exposure of the GDD occurred earlier for women than for men (58 vs 61 months; p=0.024).White race (vs black) was also associated with increased risk of GDD exposure (OR 1.693 (95% CI 1.011 to 2.833)) in univariable (p=0.044) and multivariable (p=0.046) analyses. CONCLUSIONS: Women are two times more likely to experience GDD exposure than men, independent of age. White race is also a risk factor for exposure.

Duke Scholars

Published In

BMJ Open

DOI

ISSN

2044-6055

Publication Date

May 2, 2014

Volume

4

Issue

5

Start / End Page

e004560

Location

England

Related Subject Headings

  • Risk Factors
  • Retrospective Studies
  • Postoperative Complications
  • Middle Aged
  • Male
  • Humans
  • Glaucoma Drainage Implants
  • Female
  • Aged
  • 52 Psychology
 

Citation

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Muir, K. W., Lim, A., Stinnett, S., Kuo, A., Tseng, H., & Walsh, M. M. (2014). Risk factors for exposure of glaucoma drainage devices: a retrospective observational study. BMJ Open, 4(5), e004560. https://doi.org/10.1136/bmjopen-2013-004560
Muir, Kelly W., Annie Lim, Sandra Stinnett, Anthony Kuo, Henry Tseng, and Molly M. Walsh. “Risk factors for exposure of glaucoma drainage devices: a retrospective observational study.BMJ Open 4, no. 5 (May 2, 2014): e004560. https://doi.org/10.1136/bmjopen-2013-004560.
Muir KW, Lim A, Stinnett S, Kuo A, Tseng H, Walsh MM. Risk factors for exposure of glaucoma drainage devices: a retrospective observational study. BMJ Open. 2014 May 2;4(5):e004560.
Muir, Kelly W., et al. “Risk factors for exposure of glaucoma drainage devices: a retrospective observational study.BMJ Open, vol. 4, no. 5, May 2014, p. e004560. Pubmed, doi:10.1136/bmjopen-2013-004560.
Muir KW, Lim A, Stinnett S, Kuo A, Tseng H, Walsh MM. Risk factors for exposure of glaucoma drainage devices: a retrospective observational study. BMJ Open. 2014 May 2;4(5):e004560.

Published In

BMJ Open

DOI

ISSN

2044-6055

Publication Date

May 2, 2014

Volume

4

Issue

5

Start / End Page

e004560

Location

England

Related Subject Headings

  • Risk Factors
  • Retrospective Studies
  • Postoperative Complications
  • Middle Aged
  • Male
  • Humans
  • Glaucoma Drainage Implants
  • Female
  • Aged
  • 52 Psychology