KEAP1 has a sweet spot: A new connection between intracellular glycosylation and redox stress signaling in cancer cells.
Publication
, Journal Article
Chen, P-H; Chi, J-T; Boyce, M
Published in: Mol Cell Oncol
2017
The KEAP1/NRF2 pathway is a master regulator of the redox stress response and is dysregulated in numerous human tumors. We discovered that NRF2 signaling is controlled by the site-specific glycosylation of KEAP1, revealing a potentially broad link among nutrient sensing, proteostasis and stress resistance in both normal and cancer cells.
Duke Scholars
Published In
Mol Cell Oncol
DOI
ISSN
2372-3556
Publication Date
2017
Volume
4
Issue
6
Start / End Page
e1361501
Location
United States
Related Subject Headings
- 3211 Oncology and carcinogenesis
- 3205 Medical biochemistry and metabolomics
Citation
APA
Chicago
ICMJE
MLA
NLM
Chen, P.-H., Chi, J.-T., & Boyce, M. (2017). KEAP1 has a sweet spot: A new connection between intracellular glycosylation and redox stress signaling in cancer cells. Mol Cell Oncol, 4(6), e1361501. https://doi.org/10.1080/23723556.2017.1361501
Chen, Po-Han, Jen-Tsan Chi, and Michael Boyce. “KEAP1 has a sweet spot: A new connection between intracellular glycosylation and redox stress signaling in cancer cells.” Mol Cell Oncol 4, no. 6 (2017): e1361501. https://doi.org/10.1080/23723556.2017.1361501.
Chen P-H, Chi J-T, Boyce M. KEAP1 has a sweet spot: A new connection between intracellular glycosylation and redox stress signaling in cancer cells. Mol Cell Oncol. 2017;4(6):e1361501.
Chen, Po-Han, et al. “KEAP1 has a sweet spot: A new connection between intracellular glycosylation and redox stress signaling in cancer cells.” Mol Cell Oncol, vol. 4, no. 6, 2017, p. e1361501. Pubmed, doi:10.1080/23723556.2017.1361501.
Chen P-H, Chi J-T, Boyce M. KEAP1 has a sweet spot: A new connection between intracellular glycosylation and redox stress signaling in cancer cells. Mol Cell Oncol. 2017;4(6):e1361501.
Published In
Mol Cell Oncol
DOI
ISSN
2372-3556
Publication Date
2017
Volume
4
Issue
6
Start / End Page
e1361501
Location
United States
Related Subject Headings
- 3211 Oncology and carcinogenesis
- 3205 Medical biochemistry and metabolomics