Enhanced depth penetration by dual-axis optical coherence tomography
Publication
, Conference
Zhao, Y; Chu, KK; Wax, A
Published in: Progress in Biomedical Optics and Imaging - Proceedings of SPIE
January 1, 2019
Optical imaging techniques generally offer shallow penetration depths due to high scattering in biological tissue. We have recently developed dual-axis optical coherence tomography (DA-OCT) for interferometric imaging at extended depths. By illuminating and collecting at oblique angles, multiply forward scattered photons from deeper penetration depths were favorably detected. A Monte Carlo study demonstrated a >12-fold increase in signal-to-background ratio (SBR) in skin tissue at 1 mm depth by DA-OCT. A 1300 nm DA-OCT system was designed and constructed, offering an imaging depth of up to 2 mm in skin tissue.
Duke Scholars
Published In
Progress in Biomedical Optics and Imaging - Proceedings of SPIE
DOI
ISSN
1605-7422
Publication Date
January 1, 2019
Volume
10867
Citation
APA
Chicago
ICMJE
MLA
NLM
Zhao, Y., Chu, K. K., & Wax, A. (2019). Enhanced depth penetration by dual-axis optical coherence tomography. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE (Vol. 10867). https://doi.org/10.1117/12.2507242
Zhao, Y., K. K. Chu, and A. Wax. “Enhanced depth penetration by dual-axis optical coherence tomography.” In Progress in Biomedical Optics and Imaging - Proceedings of SPIE, Vol. 10867, 2019. https://doi.org/10.1117/12.2507242.
Zhao Y, Chu KK, Wax A. Enhanced depth penetration by dual-axis optical coherence tomography. In: Progress in Biomedical Optics and Imaging - Proceedings of SPIE. 2019.
Zhao, Y., et al. “Enhanced depth penetration by dual-axis optical coherence tomography.” Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 10867, 2019. Scopus, doi:10.1117/12.2507242.
Zhao Y, Chu KK, Wax A. Enhanced depth penetration by dual-axis optical coherence tomography. Progress in Biomedical Optics and Imaging - Proceedings of SPIE. 2019.
Published In
Progress in Biomedical Optics and Imaging - Proceedings of SPIE
DOI
ISSN
1605-7422
Publication Date
January 1, 2019
Volume
10867