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Enhanced depth penetration by dual-axis optical coherence tomography

Publication ,  Conference
Zhao, Y; Chu, KK; Wax, A
Published in: Progress in Biomedical Optics and Imaging Proceedings of SPIE
January 1, 2019

Optical imaging techniques generally offer shallow penetration depths due to high scattering in biological tissue. We have recently developed dual-axis optical coherence tomography (DA-OCT) for interferometric imaging at extended depths. By illuminating and collecting at oblique angles, multiply forward scattered photons from deeper penetration depths were favorably detected. A Monte Carlo study demonstrated a >12-fold increase in signal-to-background ratio (SBR) in skin tissue at 1 mm depth by DA-OCT. A 1300 nm DA-OCT system was designed and constructed, offering an imaging depth of up to 2 mm in skin tissue.

Duke Scholars

Published In

Progress in Biomedical Optics and Imaging Proceedings of SPIE

DOI

ISSN

1605-7422

Publication Date

January 1, 2019

Volume

10867
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Zhao, Y., Chu, K. K., & Wax, A. (2019). Enhanced depth penetration by dual-axis optical coherence tomography. In Progress in Biomedical Optics and Imaging Proceedings of SPIE (Vol. 10867). https://doi.org/10.1117/12.2507242
Zhao, Y., K. K. Chu, and A. Wax. “Enhanced depth penetration by dual-axis optical coherence tomography.” In Progress in Biomedical Optics and Imaging Proceedings of SPIE, Vol. 10867, 2019. https://doi.org/10.1117/12.2507242.
Zhao Y, Chu KK, Wax A. Enhanced depth penetration by dual-axis optical coherence tomography. In: Progress in Biomedical Optics and Imaging Proceedings of SPIE. 2019.
Zhao, Y., et al. “Enhanced depth penetration by dual-axis optical coherence tomography.” Progress in Biomedical Optics and Imaging Proceedings of SPIE, vol. 10867, 2019. Scopus, doi:10.1117/12.2507242.
Zhao Y, Chu KK, Wax A. Enhanced depth penetration by dual-axis optical coherence tomography. Progress in Biomedical Optics and Imaging Proceedings of SPIE. 2019.

Published In

Progress in Biomedical Optics and Imaging Proceedings of SPIE

DOI

ISSN

1605-7422

Publication Date

January 1, 2019

Volume

10867