Structural and mechanical study of a self-assembling protein nanotube.
Publication
, Journal Article
Graveland-Bikker, JF; Schaap, IAT; Schmidt, CF; de Kruif, CG
Published in: Nano letters
April 2006
We report a structural characterization of self-assembling nanostructures. Using atomic force microscopy (AFM), we discovered that partially hydrolyzed alpha-lactalbumin organizes in a 10-start helix forming tubes with diameters of only 21 nm. We probed the mechanical strength of these nanotubes by locally indenting them with an AFM tip. To extract the material properties of the nanotubes, we modeled the experiment using finite element methods. Our study shows that artificial helical protein self-assembly can yield very stable, strong structures that can function either as a model system for artificial self-assembly or as a nanostructure with potential for practical applications.
Duke Scholars
Published In
Nano letters
DOI
EISSN
1530-6992
ISSN
1530-6984
Publication Date
April 2006
Volume
6
Issue
4
Start / End Page
616 / 621
Related Subject Headings
- Tensile Strength
- Stress, Mechanical
- Protein Conformation
- Protein Binding
- Particle Size
- Nanotubes
- Nanotechnology
- Nanoscience & Nanotechnology
- Multiprotein Complexes
- Models, Chemical
Citation
APA
Chicago
ICMJE
MLA
NLM
Graveland-Bikker, J. F., Schaap, I. A. T., Schmidt, C. F., & de Kruif, C. G. (2006). Structural and mechanical study of a self-assembling protein nanotube. Nano Letters, 6(4), 616–621. https://doi.org/10.1021/nl052205h
Graveland-Bikker, J. F., I. A. T. Schaap, C. F. Schmidt, and C. G. de Kruif. “Structural and mechanical study of a self-assembling protein nanotube.” Nano Letters 6, no. 4 (April 2006): 616–21. https://doi.org/10.1021/nl052205h.
Graveland-Bikker JF, Schaap IAT, Schmidt CF, de Kruif CG. Structural and mechanical study of a self-assembling protein nanotube. Nano letters. 2006 Apr;6(4):616–21.
Graveland-Bikker, J. F., et al. “Structural and mechanical study of a self-assembling protein nanotube.” Nano Letters, vol. 6, no. 4, Apr. 2006, pp. 616–21. Epmc, doi:10.1021/nl052205h.
Graveland-Bikker JF, Schaap IAT, Schmidt CF, de Kruif CG. Structural and mechanical study of a self-assembling protein nanotube. Nano letters. 2006 Apr;6(4):616–621.
Published In
Nano letters
DOI
EISSN
1530-6992
ISSN
1530-6984
Publication Date
April 2006
Volume
6
Issue
4
Start / End Page
616 / 621
Related Subject Headings
- Tensile Strength
- Stress, Mechanical
- Protein Conformation
- Protein Binding
- Particle Size
- Nanotubes
- Nanotechnology
- Nanoscience & Nanotechnology
- Multiprotein Complexes
- Models, Chemical