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Biomedical applications of RNA-based devices

Publication ,  Journal Article
Kim, CM; Smolke, CD
Published in: Current Opinion in Biomedical Engineering
December 1, 2017

Emergent RNA technologies employ sequence and structural information to perform a diversity of biological functions. Synthetic RNA molecules have been developed for a wide array of applications, including genetic regulation, environmental sensing, and diagnostics devices. Recent advances in chemical synthesis and computational design of RNA have enhanced our ability to program novel functions and expand upon current biomedical applications for therapeutics and diagnostics. In this review, we highlight recent advances in synthetic RNA devices that have been engineered for biomedical systems, while addressing the current limitations and challenges of translating these engineered functional RNAs to clinical applications.

Duke Scholars

Published In

Current Opinion in Biomedical Engineering

DOI

EISSN

2468-4511

Publication Date

December 1, 2017

Volume

4

Start / End Page

106 / 115

Related Subject Headings

  • 4003 Biomedical engineering
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Kim, C. M., & Smolke, C. D. (2017). Biomedical applications of RNA-based devices. Current Opinion in Biomedical Engineering, 4, 106–115. https://doi.org/10.1016/j.cobme.2017.10.005
Kim, C. M., and C. D. Smolke. “Biomedical applications of RNA-based devices.” Current Opinion in Biomedical Engineering 4 (December 1, 2017): 106–15. https://doi.org/10.1016/j.cobme.2017.10.005.
Kim CM, Smolke CD. Biomedical applications of RNA-based devices. Current Opinion in Biomedical Engineering. 2017 Dec 1;4:106–15.
Kim, C. M., and C. D. Smolke. “Biomedical applications of RNA-based devices.” Current Opinion in Biomedical Engineering, vol. 4, Dec. 2017, pp. 106–15. Scopus, doi:10.1016/j.cobme.2017.10.005.
Kim CM, Smolke CD. Biomedical applications of RNA-based devices. Current Opinion in Biomedical Engineering. 2017 Dec 1;4:106–115.
Journal cover image

Published In

Current Opinion in Biomedical Engineering

DOI

EISSN

2468-4511

Publication Date

December 1, 2017

Volume

4

Start / End Page

106 / 115

Related Subject Headings

  • 4003 Biomedical engineering