Biomedical applications of RNA-based devices
Publication
, Journal Article
Kim, CM; Smolke, CD
Published in: Current Opinion in Biomedical Engineering
December 1, 2017
Emergent RNA technologies employ sequence and structural information to perform a diversity of biological functions. Synthetic RNA molecules have been developed for a wide array of applications, including genetic regulation, environmental sensing, and diagnostics devices. Recent advances in chemical synthesis and computational design of RNA have enhanced our ability to program novel functions and expand upon current biomedical applications for therapeutics and diagnostics. In this review, we highlight recent advances in synthetic RNA devices that have been engineered for biomedical systems, while addressing the current limitations and challenges of translating these engineered functional RNAs to clinical applications.
Duke Scholars
Published In
Current Opinion in Biomedical Engineering
DOI
EISSN
2468-4511
Publication Date
December 1, 2017
Volume
4
Start / End Page
106 / 115
Related Subject Headings
- 4003 Biomedical engineering
Citation
APA
Chicago
ICMJE
MLA
NLM
Kim, C. M., & Smolke, C. D. (2017). Biomedical applications of RNA-based devices. Current Opinion in Biomedical Engineering, 4, 106–115. https://doi.org/10.1016/j.cobme.2017.10.005
Kim, C. M., and C. D. Smolke. “Biomedical applications of RNA-based devices.” Current Opinion in Biomedical Engineering 4 (December 1, 2017): 106–15. https://doi.org/10.1016/j.cobme.2017.10.005.
Kim CM, Smolke CD. Biomedical applications of RNA-based devices. Current Opinion in Biomedical Engineering. 2017 Dec 1;4:106–15.
Kim, C. M., and C. D. Smolke. “Biomedical applications of RNA-based devices.” Current Opinion in Biomedical Engineering, vol. 4, Dec. 2017, pp. 106–15. Scopus, doi:10.1016/j.cobme.2017.10.005.
Kim CM, Smolke CD. Biomedical applications of RNA-based devices. Current Opinion in Biomedical Engineering. 2017 Dec 1;4:106–115.
Published In
Current Opinion in Biomedical Engineering
DOI
EISSN
2468-4511
Publication Date
December 1, 2017
Volume
4
Start / End Page
106 / 115
Related Subject Headings
- 4003 Biomedical engineering