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Unwinding the Role of FACT in Cas9-based Genome Editing.

Publication ,  Journal Article
Cosgrove, BD; Gersbach, CA
Published in: Molecular cell
August 2020

In a recent issue of Molecular Cell, Wang et al. (2020) employ unbiased proteomics approaches and live-cell imaging to reveal a key role for the histone chaperone complex FACT (SPT16 and SSRP1) in governing Cas9 turnover at the DNA target site during genome and epigenome editing.

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Published In

Molecular cell

DOI

EISSN

1097-4164

ISSN

1097-2765

Publication Date

August 2020

Volume

79

Issue

3

Start / End Page

365 / 367

Related Subject Headings

  • RNA, Long Noncoding
  • Histones
  • Gene Editing
  • Developmental Biology
  • DNA-Binding Proteins
  • CRISPR-Cas Systems
  • 42 Health sciences
  • 32 Biomedical and clinical sciences
  • 31 Biological sciences
  • 11 Medical and Health Sciences
 

Citation

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Cosgrove, B. D., & Gersbach, C. A. (2020). Unwinding the Role of FACT in Cas9-based Genome Editing. Molecular Cell, 79(3), 365–367. https://doi.org/10.1016/j.molcel.2020.07.016
Cosgrove, Brian D., and Charles A. Gersbach. “Unwinding the Role of FACT in Cas9-based Genome Editing.Molecular Cell 79, no. 3 (August 2020): 365–67. https://doi.org/10.1016/j.molcel.2020.07.016.
Cosgrove BD, Gersbach CA. Unwinding the Role of FACT in Cas9-based Genome Editing. Molecular cell. 2020 Aug;79(3):365–7.
Cosgrove, Brian D., and Charles A. Gersbach. “Unwinding the Role of FACT in Cas9-based Genome Editing.Molecular Cell, vol. 79, no. 3, Aug. 2020, pp. 365–67. Epmc, doi:10.1016/j.molcel.2020.07.016.
Cosgrove BD, Gersbach CA. Unwinding the Role of FACT in Cas9-based Genome Editing. Molecular cell. 2020 Aug;79(3):365–367.
Journal cover image

Published In

Molecular cell

DOI

EISSN

1097-4164

ISSN

1097-2765

Publication Date

August 2020

Volume

79

Issue

3

Start / End Page

365 / 367

Related Subject Headings

  • RNA, Long Noncoding
  • Histones
  • Gene Editing
  • Developmental Biology
  • DNA-Binding Proteins
  • CRISPR-Cas Systems
  • 42 Health sciences
  • 32 Biomedical and clinical sciences
  • 31 Biological sciences
  • 11 Medical and Health Sciences