Unwinding the Role of FACT in Cas9-based Genome Editing.
Publication
, Journal Article
Cosgrove, BD; Gersbach, CA
Published in: Molecular Cell
August 2020
In a recent issue of Molecular Cell, Wang et al. (2020) employ unbiased proteomics approaches and live-cell imaging to reveal a key role for the histone chaperone complex FACT (SPT16 and SSRP1) in governing Cas9 turnover at the DNA target site during genome and epigenome editing.
Duke Scholars
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Published In
Molecular Cell
DOI
EISSN
1097-4164
ISSN
1097-2765
Publication Date
August 2020
Volume
79
Issue
3
Start / End Page
365 / 367
Related Subject Headings
- RNA, Long Noncoding
- Histones
- Gene Editing
- Developmental Biology
- DNA-Binding Proteins
- CRISPR-Cas Systems
- 11 Medical and Health Sciences
- 06 Biological Sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Cosgrove, B. D., & Gersbach, C. A. (2020). Unwinding the Role of FACT in Cas9-based Genome Editing. Molecular Cell, 79(3), 365–367. https://doi.org/10.1016/j.molcel.2020.07.016
Cosgrove, Brian D., and Charles A. Gersbach. “Unwinding the Role of FACT in Cas9-based Genome Editing.” Molecular Cell 79, no. 3 (August 2020): 365–67. https://doi.org/10.1016/j.molcel.2020.07.016.
Cosgrove BD, Gersbach CA. Unwinding the Role of FACT in Cas9-based Genome Editing. Molecular Cell. 2020 Aug;79(3):365–7.
Cosgrove, Brian D., and Charles A. Gersbach. “Unwinding the Role of FACT in Cas9-based Genome Editing.” Molecular Cell, vol. 79, no. 3, Aug. 2020, pp. 365–67. Epmc, doi:10.1016/j.molcel.2020.07.016.
Cosgrove BD, Gersbach CA. Unwinding the Role of FACT in Cas9-based Genome Editing. Molecular Cell. 2020 Aug;79(3):365–367.
Published In
Molecular Cell
DOI
EISSN
1097-4164
ISSN
1097-2765
Publication Date
August 2020
Volume
79
Issue
3
Start / End Page
365 / 367
Related Subject Headings
- RNA, Long Noncoding
- Histones
- Gene Editing
- Developmental Biology
- DNA-Binding Proteins
- CRISPR-Cas Systems
- 11 Medical and Health Sciences
- 06 Biological Sciences